Nutrients, Vol. 12, Pages 1092: Large Neutral Amino Acids (LNAAs) Supplementation Improves Neuropsychological Performances in Adult Patients with Phenylketonuria Nutrients doi: 10.3390/nu12041092 Authors: Iris Scala Maria Pia Riccio Maria Marino Carmela Bravaccio Giancarlo Parenti Pietro Strisciuglio Phenylketonuria is an inborn error of phenylalanine (Phe) metabolism diagnosed by newborn screening and treated early with diet. Although diet prevents intellectual disability,...
Wed Apr 15, 2020 03:00
Nutrients, Vol. 12, Pages 1094: Dietary Intake of Free Sugars is Associated with Disease Activity and Dyslipidemia in Systemic Lupus Erythematosus Patients Nutrients doi: 10.3390/nu12041094 Authors: María Correa-Rodríguez Gabriela Pocovi-Gerardino José-Luis Callejas-Rubio Raquel Ríos Fernández María Martín-Amada María-Gracia Cruz-Caparros Irene Medina-Martínez Norberto Ortego-Centeno Blanca Rueda-Medina Diet has been closely associated with inflammatory autoimmune...
Wed Apr 15, 2020 03:00
Nutrients, Vol. 12, Pages 1096: You Are What You Eat—The Relationship between Diet, Microbiota, and Metabolic Disorders—A Review Nutrients doi: 10.3390/nu12041096 Authors: Moszak Szulińska Bogdański The gut microbiota (GM) is defined as the community of microorganisms (bacteria, archaea, fungi, viruses) colonizing the gastrointestinal tract. GM regulates various metabolic pathways in the host, including those involved in energy homeostasis, glucose and lipid metabolism, and...
Wed Apr 15, 2020 03:00
Nutrients, Vol. 12, Pages 1091: Nutrition and Lifestyle Behavior Peer Support Program for Adults with Metabolic Syndrome: Outcomes and Lessons Learned from a Feasibility Trial Nutrients doi: 10.3390/nu12041091 Authors: Muhammad Daniel Azlan Mahadzir Kia Fatt Quek Amutha Ramadas Background: While peer support interventions have shown to benefit adults with certain chronic conditions, there is limited evidence on its feasibility and effectiveness among people with metabolic syndrome...
Wed Apr 15, 2020 03:00
Nutrients, Vol. 12, Pages 1095: Does Caesarean Section or Preterm Delivery Influence TGF-β2 Concentrations in Human Colostrum? Nutrients doi: 10.3390/nu12041095 Authors: Kociszewska-Najman Sibanda Radomska-Leśniewska Taradaj Kociołek Ginda Gruszfeld Jankowska-Steifer Pietrzak Wielgoś Malejczyk Human colostrum (HC) is a rich source of immune mediators that play a role in immune defences of a newly born infant. The mediators include transforming...
Wed Apr 15, 2020 03:00
Nutrients, Vol. 12, Pages 1090: Comparative Kinetics of Acetyl- and Butyryl-Cholinesterase Inhibition by Green Tea Catechins|Relevance to the Symptomatic Treatment of Alzheimer’s Disease Nutrients doi: 10.3390/nu12041090 Authors: Edward J. Okello Joshua Mather Alzheimer’s disease (AD) is characterised by the apoptosis of cholinergic neurons and the consequent attenuation of acetylcholine mediated neurotransmission, resulting in neurodegeneration. Acetyl-cholinesterase (AChE)...
Wed Apr 15, 2020 03:00
Nutrients, Vol. 12, Pages 1088: Dietary Factors and Risks of Cardiovascular Diseases: An Umbrella Review Nutrients doi: 10.3390/nu12041088 Authors: Kridsada Chareonrungrueangchai Keerati Wongkawinwoot Thunyarat Anothaisintawee Sirimon Reutrakul Unhealthy diet is a significant risk factor for cardiovascular diseases (CVD). Therefore, this umbrella review aims to comprehensively review the effects of dietary factors, including dietary patterns, food groups, and nutrients on CVD...
Wed Apr 15, 2020 03:00
Nutrients, Vol. 12, Pages 1089: Anti-Inflammatory and Antioxidant Effects of Anthocyanins of Trifolium pratense (Red Clover) in Lipopolysaccharide-Stimulated RAW-267.4 Macrophages Nutrients doi: 10.3390/nu12041089 Authors: Sang Gil Lee Cindi R. Brownmiller Sun-Ok Lee Hye Won Kang Red clover (Trifolium pratense) possesses various dietary compounds that improve human health. However, the functions of anthocyanins in red clover remain unclear. Here we examined anti-inflammatory...
Wed Apr 15, 2020 03:00
Nutrients, Vol. 12, Pages 1087: Inconsistency in the Ergogenic Effect of Caffeine in Athletes Who Regularly Consume Caffeine: Is It Due to the Disparity in the Criteria That Defines Habitual Caffeine Intake? Nutrients doi: 10.3390/nu12041087 Authors: Aleksandra Filip Michal Wilk Michal Krzysztofik Juan Del Coso Caffeine is the most popular psychoactive substance in the world, and data suggests that it is widely used by athletes before competition to enhance physical and mental...
Wed Apr 15, 2020 03:00
Pathogens, Vol. 9, Pages 288: Prevention of Intramammary Infections by Prepartum External Application of a Teat Dip Containing Lactic Acid Bacteria with Antimicrobial Properties in Dairy Heifers Pathogens doi: 10.3390/pathogens9040288 Authors: Jan-Hendrik Paduch Johanna Lücking Ellen Mansion-de Vries Claudia Zinke Nicole Wente Volker Krömker The aim of the current study was to investigate the effects of the prepartum external treatment of teats with a combination of four...
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Pathogens, Vol. 9, Pages 289: The Role of Long Noncoding RNAs in Human Papillomavirus-associated Pathogenesis Pathogens doi: 10.3390/pathogens9040289 Authors: Surendra Sharma Karl Munger Infections with high-risk human papillomaviruses cause ~5% of all human cancers. E6 and E7 are the only viral genes that are consistently expressed in cancers, and they are necessary for tumor initiation, progression, and maintenance. E6 and E7 encode small proteins that lack intrinsic enzymatic activities...
Wed Apr 15, 2020 03:00
Pathogens, Vol. 9, Pages 286: Legionella pneumophila and Protozoan Hosts: Implications for the Control of Hospital and Potable Water Systems Pathogens doi: 10.3390/pathogens9040286 Authors: Nisar Ross Brown Bentham Whiley Legionella pneumophila is an opportunistic waterborne pathogen of public health concern. It is the causative agent of Legionnaires’ disease (LD) and Pontiac fever and is ubiquitous in manufactured water systems, where protozoan hosts and complex...
Wed Apr 15, 2020 03:00
Pathogens, Vol. 9, Pages 287: The Complex Relationship between HTLV-1 and Nonsense-Mediated mRNA Decay (NMD) Pathogens doi: 10.3390/pathogens9040287 Authors: Prochasson Jalinot Mocquet Before the establishment of an adaptive immune response, retroviruses can be targeted by several cellular host factors at different stages of the viral replication cycle. This intrinsic immunity relies on a large diversity of antiviral processes. In the case of HTLV-1 infection, these active innate...
Wed Apr 15, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 68: In-Vitro Evaluation of Antioxidant, Antiproliferative and Photo-Protective Activities of Benzimidazolehydrazone Derivatives Pharmaceuticals doi: 10.3390/ph13040068 Authors: Baldisserotto Demurtas Lampronti Tacchini Moi Balboni Vertuani Manfredini Onnis In the search of multifunctional compounds we designed benzimidazole derivatives endowed with phenolic hydroxy groups and a hydrazone moiety as potential radical-scavenger...
Wed Apr 15, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 67: Oral l-Cysteine Supplementation Enhances the Long Term-Effect of Topical Basic Fibroblast Growth Factor (bFGF) in Reducing the Corneal Haze after Photorefractive Keratectomy in Myopic Patients Pharmaceuticals doi: 10.3390/ph13040067 Authors: Meduri Bergandi Perroni Silvagno Aragona We aimed at evaluating the long-term effects of l-cysteine oral supplementation to basic fibroblast growth factor (bFGF) eye-drops on corneal re-epithelization...
Wed Apr 15, 2020 03:00
Pharmaceutics, Vol. 12, Pages 361: “Smart” Antimicrobial Nanocomplexes with Potential to Decrease Surgical Site Infections (SSI) Pharmaceutics doi: 10.3390/pharmaceutics12040361 Authors: Edis Haj Bloukh Ibrahim Abu Sara The emergence of resistant pathogens is a burden on mankind and threatens the existence of our species. Natural and plant-derived antimicrobial agents need to be developed in the race against antibiotic resistance. Nanotechnology is a promising approach with...
Wed Apr 15, 2020 03:00
Pharmaceutics, Vol. 12, Pages 362: Development of 20(S)-Protopanaxadiol-Loaded SNEDDS Preconcentrate Using Comprehensive Phase Diagram for the Enhanced Dissolution and Oral Bioavailability Pharmaceutics doi: 10.3390/pharmaceutics12040362 Authors: Young Hoon Kim Yu Chul Kim Dong-Jin Jang Kyoung Ah Min Jenisha Karmacharya Thi-Thao-Linh Nguyen Han-Joo Maeng Kwan Hyung Cho In this study, we aimed to develop a 20(S)-protopanaxadiol (PPD)-loaded self-nanoemulsifying drug...
Wed Apr 15, 2020 03:00
Pharmaceutics, Vol. 12, Pages 360: In Situ Gelling Ophthalmic Drug Delivery System for the Optimization of Diagnostic and Preoperative Mydriasis: In Vitro Drug Release, Cytotoxicity and Mydriasis Pharmacodynamics Pharmaceutics doi: 10.3390/pharmaceutics12040360 Authors: Pierre-Louis Destruel Ni Zeng Françoise Brignole-Baudouin Sophie Douat Johanne Seguin Elodie Olivier Melody Dutot Patrice Rat Sophie Dufaÿ Amélie Dufaÿ-Wojcicki Marc Maury Nathalie Mignet Vincent...
Wed Apr 15, 2020 03:00
Pharmaceutics, Vol. 12, Pages 359: Application of 1-Hydroxy-4,5-Dimethyl-Imidazole 3-Oxide as Coformer in Formation of Pharmaceutical Cocrystals Pharmaceutics doi: 10.3390/pharmaceutics12040359 Authors: Aneta Wróblewska Justyna Śniechowska Sławomir Kaźmierski Ewelina Wielgus Grzegorz D. Bujacz Grzegorz Mlostoń Arkadiusz Chworos Justyna Suwara Marek J. Potrzebowski Two, well defined binary crystals with 1-Hydroxy-4,5-Dimethyl-Imidazole 3-Oxide (HIMO) as coformer...
Wed Apr 15, 2020 03:00
Pharmacy, Vol. 8, Pages 66: Embracing the Evolution of Pharmacy Practice by Empowering Pharmacy Technicians Pharmacy doi: 10.3390/pharmacy8020066 Authors: Burke While pharmacy technician roles in some practice settings are expanding beyond the traditional dispensing activities to include advanced or specialized tasks such as immunization administration, medication history collection, and final product verification, these practices are not yet widespread. There are apparent barriers...
Wed Apr 15, 2020 03:00
Pharmacy, Vol. 8, Pages 65: Impact of Up-Scheduling Medicines on Pharmacy Personnel, Using Codeine as an Example, with Possible Adaption to Complementary Medicines: A Scoping Review Pharmacy doi: 10.3390/pharmacy8020065 Authors: Kristenbella AYR Lee Joanna E. Harnett Carolina Oi Lam Ung Betty Chaar Within Australia, vitamins, minerals, nutritional supplements, essential oils, and homoeopathic and herbal preparations are collectively termed and regulated as Complementary Medicines...
Wed Apr 15, 2020 03:00
Philosophies, Vol. 5, Pages 7: Multiplicity of Research Programs in the Biological Systematics: A Case for Scientific Pluralism Philosophies doi: 10.3390/philosophies5020007 Authors: Igor Y. Pavlinov Biological diversity (BD) explored by biological systematics is a complex yet organized natural phenomenon and can be partitioned into several aspects, defined naturally with reference to various causal factors structuring biota. These BD aspects are studied by particular research programs...
Wed Apr 15, 2020 03:00
Plants, Vol. 9, Pages 510: Leaf Water Relations in Lime Trees Grown under Shade Netting and Open-Air
Plants, Vol. 9, Pages 510: Leaf Water Relations in Lime Trees Grown under Shade Netting and Open-Air Plants doi: 10.3390/plants9040510 Authors: Mira-García Conejero Vera Ruiz-Sánchez Physiological plant water status indicators are useful for managing precision irrigation in regions with limited water resources. The aim of this work was to evaluate the effect of shade netting on the diurnal and seasonal variations of several plant water status indicators in young lime trees...
Wed Apr 15, 2020 03:00
Plants, Vol. 9, Pages 508: Eco-Physiological Screening of Different Tomato Genotypes in Response to High Temperatures: A Combined Field-to-Laboratory Approach Plants doi: 10.3390/plants9040508 Authors: Arena Conti Francesca Melchionna Hájek Barták Barone Rigano High temperatures represent a limitation for growth and development of many crop species. Several studies have demonstrated that the yield reduction of tomato under high temperatures and drought...
Wed Apr 15, 2020 03:00
Plants, Vol. 9, Pages 509: Thrips as the Transmission Bottleneck for Mixed Infection of Two Orthotospoviruses Plants doi: 10.3390/plants9040509 Authors: Zhao Rosa Mixed infections provide opportunities for viruses to increase genetic diversity by facilitating genomic reassortment or recombination, and they may lead to the emergence of new virus species. Mixed infections of two economically important orthotospoviruses, Tomato spotted wilt orthotospovirus (TSWV) and Impatiens necrotic...
Wed Apr 15, 2020 03:00
Plants, Vol. 9, Pages 507: Spinach Plants Favor the Absorption of K+ over Na+ Regardless of Salinity, and May Benefit from Na+ When K+ is Deficient in the Soil Plants doi: 10.3390/plants9040507 Authors: Jorge F. S. Ferreira Jaime Barros da Silva Filho Xuan Liu Devinder Sandhu Two spinach (Spinacea oleracea L.) cultivars were evaluated for their response to deficient (0.25 mmolc L−1 or 0.25 K) and sufficient (5.0 mmolc L−1 or 5.0 K) potassium (K) levels combined...
Wed Apr 15, 2020 03:00
Proteomes, Vol. 8, Pages 7: Analysis of Reference Ranges of Total Serum Protein in Namibia: Clinical Implications Proteomes doi: 10.3390/proteomes8020007 Authors: Josephine N. Henok Benjamin I. Okeleye Elizabeth I. Omodanisi Seteno K. O. Ntwampe Yapo G. Aboua A reference range is an essential part of clinical laboratory test interpretation and patient care. The levels of total serum protein (TSP) are measured in sera to assess nutritional, liver, and kidney disorders. This...
Wed Apr 15, 2020 03:00
Religions, Vol. 11, Pages 192: Reimagining Christian Hope(lessness) in the Anthropocene Religions doi: 10.3390/rel11040192 Authors: Timothy Robinson Faith in the Anthropocene requires a re-imagined account of Christian hope. Research on the emergence of eco-anxiety disorder shows that climate crisis and ecological destruction have psychological and emotional effects on persons and communities, producing fear, despair, and hopelessness. Accounts of hope in recent environmental literature...
Wed Apr 15, 2020 03:00
Religions, Vol. 11, Pages 191: Dabo Swinney, Universal Whiteness, and a “Sin Problem” Religions doi: 10.3390/rel11040191 Authors: Jeffrey Scholes Clemson University head football coach Dabo Swinney was asked to respond to Colin Kaepernick’s protest of police killings of unarmed black men and women by kneeling for the national anthem. Swinney’s response was surprisingly comprehensive and illuminating into his stance on race, religion, and sport. He crystallizes his...
Wed Apr 15, 2020 03:00
Resources, Vol. 9, Pages 42: Systems Engineering Approach to Slope Stability Monitoring in the Digital Mine Resources doi: 10.3390/resources9040042 Authors: Marc Elmouttie Peter Dean Slope stability monitoring in open cut mining is increasingly based on the use of a variety of different sensors and associated analytics, each capable of providing part of the understanding required to manage complex geotechnical environments. Designing an integrated monitoring system that is both attainable...
Wed Apr 15, 2020 03:00
Social Sciences, Vol. 9, Pages 53: Big Data in Education: Perception of Training Advisors on Its Use in the Educational System Social Sciences doi: 10.3390/socsci9040053 Authors: Julio Ruiz-Palmero Ernesto Colomo-Magaña José Manuel Ríos-Ariza Melchor Gómez-García Big Data has revolutionized decision making in many fields, including education. The incorporation of information and communication technologies into education enables us to gather information about the teaching and...
Wed Apr 15, 2020 03:00
Societies, Vol. 10, Pages 35: Human–Nature Relationships in East Asian Animated Films Societies doi: 10.3390/soc10020035 Authors: Yuan Pan Our relationship with nature is complex and exploring this extends beyond academia. Animated films with powerful narratives can connect humans with nature in ways that science cannot. Narratives can be transformative and shape our opinions. Nevertheless, there is little research into non-Western films with strong conservation themes. Hayao Miyazaki...
Wed Apr 15, 2020 03:00
Technologies, Vol. 8, Pages 19: Recognition of Holoscopic 3D Video Hand Gesture Using Convolutional Neural Networks Technologies doi: 10.3390/technologies8020019 Authors: Norah Alnaim Maysam Abbod Rafiq Swash The convolutional neural network (CNN) algorithm is one of the efficient techniques to recognize hand gestures. In human–computer interaction, a human gesture is a non-verbal communication mode, as users communicate with a computer via input devices. In this article,...
Wed Apr 15, 2020 03:00
Toxics, Vol. 8, Pages 30: Theoretical Modeling of Oral Glucose Tolerance Tests Guides the Interpretation of the Impact of Perinatal Cadmium Exposure on the Offspring’s Glucose Homeostasis Toxics doi: 10.3390/toxics8020030 Authors: Alexandre Rocca Eric Fanchon Jean-Marc Moulis Oral glucose tolerance tests, in which the concentration of glucose is monitored in the circulation over 2 h after ingesting a bolus, probe diabetic or pre-diabetic conditions. The resulting glucose curves...
Wed Apr 15, 2020 03:00
Toxins, Vol. 12, Pages 256: Loxoscelism: Advances and Challenges in the Design of Antibody Fragments with Therapeutic Potential Toxins doi: 10.3390/toxins12040256 Authors: Sabrina Karim-Silva Alessandra Becker-Finco Isabella Gizzi Jiacomini Fanny Boursin Arnaud Leroy Magali Noiray Juliana de Moura Nicolas Aubrey Philippe Billiald Larissa M. Alvarenga Envenoming due to Loxosceles spider bites still remains a neglected disease of particular medical concern in...
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Toxins, Vol. 12, Pages 257: Blooms of Toxic Cyanobacterium Nodularia spumigena in Norwegian Fjords During Holocene Warm Periods Toxins doi: 10.3390/toxins12040257 Authors: Robert Konkel Anna Toruńska-Sitarz Marta Cegłowska Žilvinas Ežerinskis Justina Šapolaitė Jonas Mažeika Hanna Mazur-Marzec In paleoecological studies, molecular markers are being used increasingly often to reconstruct community structures, environmental conditions and ecosystem changes. In this work,...
Wed Apr 15, 2020 03:00
Toxins, Vol. 12, Pages 255: Hitchhiking with Nature: Snake Venom Peptides to Fight Cancer and Superbugs Toxins doi: 10.3390/toxins12040255 Authors: Pérez-Peinado Defaus Andreu For decades, natural products in general and snake venoms (SV) in particular have been a rich source of bioactive compounds for drug discovery, and they remain a promising substrate for therapeutic development. Currently, a handful of SV-based drugs for diagnosis and treatment of various cardiovascular...
Wed Apr 15, 2020 03:00
TropicalMed, Vol. 5, Pages 60: Small Session Size and Big Vial Size: Operational Research Assessing Open Vial Vaccine Wastage at the Service Delivery Points in the Mandalay Region of Myanmar During 2018 Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed5020060 Authors: Oo Thekkur Thar Htet Lin The World Health Organization (WHO) recommends immunization programmes to monitor vaccine wastage at storage and service delivery points. As there were no vaccine...
Wed Apr 15, 2020 03:00
TropicalMed, Vol. 5, Pages 59: Rickettsial Diseases: Not Uncommon Causes of Acute Febrile Illness in India Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed5020059 Authors: Manisha Biswal Sivanantham Krishnamoorthi Kamlesh Bisht Amit Sehgal Jasleen Kaur Navneet Sharma Vikas Suri Sunil Sethi Rickettsial diseases (RDs) are major under-diagnosed causes of arthropod borne acute febrile illness (AFI) presenting with a range of symptoms from mild self-limiting...
Wed Apr 15, 2020 03:00
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