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Τετάρτη 29 Απριλίου 2020

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Increased Tissue Expression of Lectin-Like Oxidized LDL Receptor-1 (LOX-1) Is Associated with Disease Severity in Chronic Rhinosinusitis with Nasal Polyps.
Related ArticlesIncreased Tissue Expression of Lectin-Like Oxidized LDL Receptor-1 (LOX-1) Is Associated with Disease Severity in Chronic Rhinosinusitis with Nasal Polyps. Diagnostics (Basel). 2020 Apr 23;10(4): Authors: Nishida M, Takeno S, Takemoto K, Takahara D, Hamamoto T, Ishino T, Kawasumi T Abstract BACKGROUND: The oxidative stress, induced by both environmental and intrinsic stimuli, underlies the onset and persistency of chronic rhinosinusitis...
Head and Neck
Wed Apr 29, 2020 13:27
Enhancing Antitumor Efficacy of Heavily Vascularized Tumors by RAMBO Virus through Decreased Tumor Endothelial Cell Activation.
Related ArticlesEnhancing Antitumor Efficacy of Heavily Vascularized Tumors by RAMBO Virus through Decreased Tumor Endothelial Cell Activation. Cancers (Basel). 2020 Apr 23;12(4): Authors: Nair M, Khosla M, Otani Y, Yeh M, Park F, Shimizu T, Kang JM, Bolyard C, Yu JG, Kumar Banasavadi-Siddegowda Y, Lopez G, Kaur B, Pollock RE, Lee TJ, Old M, Yoo JY Abstract Vascularization is a common pathology for many solid tumors, and therefore anti-angiogenic...
Head and Neck
Wed Apr 29, 2020 13:27
Continuity of Care Is Associated with Medical Costs and Inpatient Days in Children with Cerebral Palsy.
Related ArticlesContinuity of Care Is Associated with Medical Costs and Inpatient Days in Children with Cerebral Palsy. Int J Environ Res Public Health. 2020 Apr 23;17(8): Authors: Yang KT, Yin CH, Hung YM, Huang SJ, Lee CC, Kuo TJ Abstract Background: Children with cerebral palsy (CP) place a considerable burden on medical costs and add to an increased number of inpatient days in Taiwan. Continuity of care (COC) has not been investigated in this...
Head and Neck
Wed Apr 29, 2020 13:27
Mastoid Cavity Myiasis: A Case Report and Review of the Literature.
Related ArticlesMastoid Cavity Myiasis: A Case Report and Review of the Literature. Otol Neurotol. 2019 07;40(6):e627-e630 Authors: Kahane J, Longworth C, Dickson C, Ng M Abstract OBJECTIVE: We report a case study of mastoid cavity aural myiasis in an urban developed setting and review the relevant literature. DATA SOURCE: Retrospective case report and review of the English literature via PubMed. DATA SELECTION: English-language articles...
Head and Neck
Wed Apr 29, 2020 13:27
Association of Intracranial Hypertension With Calvarial and Skull Base Thinning.
Related ArticlesAssociation of Intracranial Hypertension With Calvarial and Skull Base Thinning. Otol Neurotol. 2019 07;40(6):e619-e626 Authors: Rabbani CC, Patel JM, Nag A, Schueth E, Saltagi MZ, Kao R, Nelson RF Abstract OBJECTIVE: Determine if patients with increased opening pressure (OP) on lumbar puncture (LP) have thinner calvaria and skull bases. STUDY DESIGN: Retrospective cohort study. SETTING: Tertiary referral center. ...
Head and Neck
Wed Apr 29, 2020 13:27
Orbital Compartment Syndrome After Pterional Craniotomy for Removal of Meningioma of the Frontal Lobe Without Evidence of Orbital Mass or Ocular Compression: A Case Report and Literature Review.
Related ArticlesOrbital Compartment Syndrome After Pterional Craniotomy for Removal of Meningioma of the Frontal Lobe Without Evidence of Orbital Mass or Ocular Compression: A Case Report and Literature Review. World Neurosurg. 2020 Apr 25;: Authors: Dunford JM, Miller C Abstract A 76-year-old male whose brain MRI demonstrated an anterior right frontal broad dural based homogenously enhancing mass measuring 6.0x3.1x6.3cm. after presenting with a one...
pubmed: "world neurosurg"[jo...
Wed Apr 29, 2020 15:26
Initial report of an intradural extramedullary metastasis of a pancreatic neuroendocrine tumor to the cervical spine: a case report and review of literature.
Related ArticlesInitial report of an intradural extramedullary metastasis of a pancreatic neuroendocrine tumor to the cervical spine: a case report and review of literature. World Neurosurg. 2020 Apr 25;: Authors: Saway BF, Fayed I, Dowlati MSE, Derakhshandeh R, Sandhu FA PMID: 32344144 [PubMed - as supplied by publisher]
pubmed: "world neurosurg"[jo...
Wed Apr 29, 2020 15:26
Covid-19 patients and surgery: Guidelines and checklist proposal.
Related ArticlesCovid-19 patients and surgery: Guidelines and checklist proposal. World Neurosurg. 2020 Apr 25;: Authors: Grelat M, Pommier B, Portet S, Amelot A, Barrey C, Leroy HA, Madkouri R Abstract The management of patients with novel 2019 coronavirus (Covid-19) represents a new challenge for medical and surgical teams. Each operating room in the world should be prepared with thinking and the development of a protocol and patient route seems mandatory....
pubmed: "world neurosurg"[jo...
Wed Apr 29, 2020 15:26
A case of Cowden's syndrome with 15 spinal arteriovenous fistulas.
Related ArticlesA case of Cowden's syndrome with 15 spinal arteriovenous fistulas. World Neurosurg. 2020 Apr 25;: Authors: Hedjoudje A, Peng X, Gautam A, Pardo CA, Sciubba D, Gailloud P Abstract BACKGROUND: Spinal vascular malformations (SVM) are rarely multiple: less than 50 observations have so far been documented, with a maximum of 4 coexisting lesions per patient, always restricted to a single vertebral region (e.g., cervical or thoracic). ...
pubmed: "world neurosurg"[jo...
Wed Apr 29, 2020 15:26
How safe is minimally invasive TLIF for octogenarians? - A perioperative complication analysis.
Related ArticlesHow safe is minimally invasive TLIF for octogenarians? - A perioperative complication analysis. World Neurosurg. 2020 Apr 25;: Authors: Vasilikos I, Fistouris P, Krüger MT, Scholz C, Kogias E, Roelz R, Sircar R, Juergen Beck, Hubbe U, Klingler JH PMID: 32344141 [PubMed - as supplied by publisher]
pubmed: "world neurosurg"[jo...
Wed Apr 29, 2020 15:26
Atlanto-Occipital Transarticular Screw Fixation for the Treatment of Traumatic Occipito-Cervical Instability in the Pediatric Population.
Related ArticlesAtlanto-Occipital Transarticular Screw Fixation for the Treatment of Traumatic Occipito-Cervical Instability in the Pediatric Population. World Neurosurg. 2020 Apr 25;: Authors: Hassler KR, Jamshidi R, Vail SJ, Connell MJ, Chundu K, Lettieri SC, Feiz-Erfan I PMID: 32344140 [PubMed - as supplied by publisher]
pubmed: "world neurosurg"[jo...
Wed Apr 29, 2020 15:26
Development and Validation of Machine Learning Algorithms for Predicting Adverse Events Following Surgery for Lumbar Degenerative Spondylolisthesis.
Related ArticlesDevelopment and Validation of Machine Learning Algorithms for Predicting Adverse Events Following Surgery for Lumbar Degenerative Spondylolisthesis. World Neurosurg. 2020 Apr 25;: Authors: Fatima N, Zheng H, Massaad E, Hadzipasic M, Shankar GM, Shin JH Abstract INTRODUCTION: Preoperative prognostication of adverse events (AEs) for patients undergoing surgery for lumbar degenerative spondylolisthesis (LDS) can improve risk stratification...
pubmed: "world neurosurg"[jo...
Wed Apr 29, 2020 15:26
Ultrasonographic diagnosis of lipomatosis of nerve: a review of ultrasonographic finding for 8 cases.
Related ArticlesUltrasonographic diagnosis of lipomatosis of nerve: a review of ultrasonographic finding for 8 cases. World Neurosurg. 2020 Apr 25;: Authors: Xu P, Lu B, Deng HP, Mi YR, Yin CX, Ding Y, Shao XZ, Zhang GS, Xiu XF Abstract OBJECTIVE: Lipomatosis of nerve (LN) is a rare tumour-like condition with epineural and perineural infiltration by adipose and fibrous tissue. The purpose was to analyze the ultrasonographic findings of LN involving upper...
pubmed: "world neurosurg"[jo...
Wed Apr 29, 2020 15:26
Coil embolization of wide neck bifurcation aneurysms via 'shouldering' and 'framing': a safe alternative to conventional techniques.
Related ArticlesCoil embolization of wide neck bifurcation aneurysms via 'shouldering' and 'framing': a safe alternative to conventional techniques. World Neurosurg. 2020 Apr 25;: Authors: Weinberg JH, Sweid A, Asada A, Abbas R, Joffe D, El Naamani K, Gooch MR, Herial N, Tjoumakaris S, Rosenwasser RH, Jabbour P, Zarzour H Abstract INTRODUCTION: Double stent-assisted coiling of wide-neck bifurcation aneurysms (WNBA) can be technically challenging with...
pubmed: "world neurosurg"[jo...
Wed Apr 29, 2020 15:26
Glossopharyngeal Neuropathy / Neuralgia with Hemodynamic Instability and Associated Syncope Treated with Stereotactic Radiosurgery: Case Report.
Related ArticlesGlossopharyngeal Neuropathy / Neuralgia with Hemodynamic Instability and Associated Syncope Treated with Stereotactic Radiosurgery: Case Report. World Neurosurg. 2020 Apr 25;: Authors: Banerjee C, Viers A, Vender J Abstract The incidence of glossopharyngeal neuralgia (GPN)/neuropathy (GPNo) is rare, with approximately 0.4-0.8 cases per 100,000 person-years with less than 3 percent of those cases being associated with cardiac arrhythmias...
pubmed: "world neurosurg"[jo...
Wed Apr 29, 2020 15:26
Giant Tarlov cysts with rare pelvic extension: report of 3 cases and literature review.
Related ArticlesGiant Tarlov cysts with rare pelvic extension: report of 3 cases and literature review. World Neurosurg. 2020 Apr 25;: Authors: Zhu H, Shen L, Zheng C, Yang M, Zheng X Abstract BACKGROUND: Giant presacral Tarlov cysts (TCs) with pelvic extension were extremely rare and have many special features different from normal TCs in examination, diagnosis, symptoms and treatment. We report 3 rare cases of giant presacral Tarlov cysts with pelvic...
pubmed: "world neurosurg"[jo...
Wed Apr 29, 2020 15:26
Correlation Between the Oswestry Disability Index and the North American Spine Surgery Patient Satisfaction Index.
Related ArticlesCorrelation Between the Oswestry Disability Index and the North American Spine Surgery Patient Satisfaction Index. World Neurosurg. 2020 Apr 25;: Authors: Yee TJ, Fearer KJ, Oppenlander ME, Kashlan ON, Szerlip N, Buckingham MJ, Swong K, Chang V, Schwalb JM, Park P Abstract BACKGROUND: The Oswestry Disability Index (ODI) is a widely utilized patient-reported outcome instrument in lumbar spine surgery, but its relationship to the increasingly...
pubmed: "world neurosurg"[jo...
Wed Apr 29, 2020 15:26
Unilateral or bilateral percutaneous endoscopic debridement and lavage treatment for lumbar spinal tuberculosis.
Related ArticlesUnilateral or bilateral percutaneous endoscopic debridement and lavage treatment for lumbar spinal tuberculosis. World Neurosurg. 2020 Apr 25;: Authors: Wu D, Sun J, Fan W, Yuan F Abstract AIM: To compare the clinical outcome between bilateral percutaneous endoscopic debridement and lavage (PEDL) and unilateral PEDL treatment for lumbar spine tuberculosis (LST). METHODS: A total of 40 patients with LST who underwent either bilateral...
pubmed: "world neurosurg"[jo...
Wed Apr 29, 2020 15:26
Lessons from China when Performing Neurosurgical Procedures During the COVID-19 Pandemic.
Related ArticlesLessons from China when Performing Neurosurgical Procedures During the COVID-19 Pandemic. World Neurosurg. 2020 Apr 25;: Authors: Wen J, Qi X, Lyon KA, Liang B, Wang X, Feng D, Huang JH PMID: 32344132 [PubMed - as supplied by publisher]
pubmed: "world neurosurg"[jo...
Wed Apr 29, 2020 15:26
Spinal subdural hematoma due to the removal of cerebrospinal fluid drainage tube during thoracic endovascular aortic repair.
Related ArticlesSpinal subdural hematoma due to the removal of cerebrospinal fluid drainage tube during thoracic endovascular aortic repair. World Neurosurg. 2020 Apr 25;: Authors: Mitsuoka H, Orimoto Y, Hagihara M, Suzuki K, Arima T, Isaji T, Takayasu M, Ishibashi H Abstract BACKGROUND: Cerebrospinal fluid (CSF) drainage during the treatment of aortic disease is commonly performed to prevent spinal cord ischemia (SCI). Spinal subdural hematoma (SDH)...
pubmed: "world neurosurg"[jo...
Wed Apr 29, 2020 15:26
Incidence, Treatment and Survival in Primary Central Nervous System Neuroblastoma.
Related ArticlesIncidence, Treatment and Survival in Primary Central Nervous System Neuroblastoma. World Neurosurg. 2020 Apr 25;: Authors: Lu X, Zhang X, Deng X, Yang Z, Shen X, Sheng H, Yin B, Zhang N, Lin J Abstract BACKGROUND: Primary central nervous system neuroblastoma (PCNSN) is a rare disease, and its incidence, treatment modalities, and survival remain poorly understood. METHODS: The SEER database was used to identify patients diagnosed...
pubmed: "world neurosurg"[jo...
Wed Apr 29, 2020 15:26
Genetic mutational analysis of β-catenin gene affecting GSK-3β phosphorylation plays a role in gallbladder carcinogenesis: Results from a case control study.
Related ArticlesGenetic mutational analysis of β-catenin gene affecting GSK-3β phosphorylation plays a role in gallbladder carcinogenesis: Results from a case control study. Cancer Treat Res Commun. 2020 Apr 21;23:100173 Authors: Dixit R, Pandey M, Tripathi SK, Dwivedi AND, Shukla VK Abstract This manuscript has reported different mutations of β-catenin gene in gallbladder cancer patients which affect GSK-3β phosphorylation site. PURPOSE: Gallbladder...
Rare Cancers
Wed Apr 29, 2020 14:21
Ewing Sarcoma presenting as a gluteal mass in adult woman: Diagnostic approach and its challenges.
Related ArticlesEwing Sarcoma presenting as a gluteal mass in adult woman: Diagnostic approach and its challenges. Malays J Pathol. 2020 Apr;42(1):121-125 Authors: Tuan Sharif SE, Alzallal O, Wan Ismail WF, Md Zin RR Abstract INTRODUCTION: Sarcomas of the Ewing family of tumours are aggressive neoplasms occurring in bone and soft tissue of mostly children and young adults. It usually affects male more than female with peak incidence 10 to 15 years of...
Rare Cancers
Wed Apr 29, 2020 14:21
Epithelial-Myoepithelial Carcinoma of the Lacrimal Sac and Literature Review of the Lacrimal System.
Related ArticlesEpithelial-Myoepithelial Carcinoma of the Lacrimal Sac and Literature Review of the Lacrimal System. Allergy Rhinol (Providence). 2020 Jan-Dec;11:2152656720920600 Authors: Sharma D, Neiweem A, Davis K, Prendes M, Chundury R, Illing E Abstract Background: Epithelial-myoepithelial carcinomas make up less than 0.1% of head and neck malignancies and are regarded as rare, low-grade malignant neoplasms of the salivary gland. They are thought...
Rare Cancers
Wed Apr 29, 2020 13:21
A phase II study of axalimogene filolisbac for patients with previously treated, unresectable, persistent/recurrent loco-regional or metastatic anal cancer.
Related ArticlesA phase II study of axalimogene filolisbac for patients with previously treated, unresectable, persistent/recurrent loco-regional or metastatic anal cancer. Oncotarget. 2020 Apr 14;11(15):1334-1343 Authors: Eng C, Fakih M, Amin M, Morris V, Hochster HS, Boland PM, Uronis H Abstract Squamous cell carcinoma of the anorectal canal (SCCA) is a rare HPV-related malignancy that is steadily increasing in incidence. A high unmet need exists for...
Rare Cancers
Wed Apr 29, 2020 13:21
Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility.
Related ArticlesGenome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility. Nat Genet. 2020 Apr 27;: Authors: Landi MT, Bishop DT, MacGregor S, Machiela MJ, Stratigos AJ, Ghiorzo P, Brossard M, Calista D, Choi J, Fargnoli MC, Zhang T, Rodolfo M, Trower AJ, Menin C, Martinez J, Hadjisavvas A, Song L, Stefanaki I, Scolyer R, Yang R, Goldstein AM, Potrony M, Kypreou KP, Pastorino...
Rare Cancers
Wed Apr 29, 2020 13:21
p27 as a transcriptional regulator: New roles in development and cancer.
Related Articlesp27 as a transcriptional regulator: New roles in development and cancer. Cancer Res. 2020 Apr 27;: Authors: Slingerland JM, Razavipour SF, Harikumar KB Abstract p27 binds and inhibits cyclin-CDK to arrest the cell cycle. p27 also regulates other processes including migration and development independent of its CDK inhibitory action. p27 is an atypical tumor suppressor: deletion or mutational inactivation of the gene encoding p27, CDKN1B,...
Rare Cancers
Wed Apr 29, 2020 13:21
[Bone marrow serous degeneration complicating acute leukemia].
Related Articles[Bone marrow serous degeneration complicating acute leukemia]. Ann Pathol. 2020 Apr 24;: Authors: Malki S, Miry A, Karich N, Bennani A Abstract INTRODUCTION: Serous degeneration of bone marrow is a rare hematological complication, of multiple etiologies, which physiopathology is yet to be fully understood. It is described as a focal hypoplasia of the bone marrow and atrophy of its adipocytes coupled with an extracellular deposit of an...
Rare Cancers
Wed Apr 29, 2020 13:21
Effect of Transgene Location, Transcriptional Control Elements and Transgene Features in Armed Oncolytic Adenoviruses.
Related ArticlesEffect of Transgene Location, Transcriptional Control Elements and Transgene Features in Armed Oncolytic Adenoviruses. Cancers (Basel). 2020 Apr 23;12(4): Authors: Farrera-Sal M, Fillat C, Alemany R Abstract Clinical results with oncolytic adenoviruses (OAds) used as antitumor monotherapies show limited efficacy. To increase OAd potency, transgenes have been inserted into their genome, a strategy known as "arming OAds". Here, we review...
Rare Cancers
Wed Apr 29, 2020 13:21
Antitumor effects of Farnesol in optic nerve sheath meningioma cell line and its effects on cell cycle progression, autophagy, cell migration and invasion.
Related ArticlesAntitumor effects of Farnesol in optic nerve sheath meningioma cell line and its effects on cell cycle progression, autophagy, cell migration and invasion. J BUON. 2019 Sep-Oct;24(5):2168-2172 Authors: Zeng C, Guo B, Chen J, He W Abstract PURPOSE: Farnesol has been shown to exhibit important anticancer potential. However, its antiproliferative effects have not been examined against the optic nerve sheath meningioma cells. In this study...
Rare Cancers
Wed Apr 29, 2020 13:21
Multiple calcifying fibrous pseudotumors of the pleura: ultrastructural analysis provides insight on mechanism of dissemination.
Related ArticlesMultiple calcifying fibrous pseudotumors of the pleura: ultrastructural analysis provides insight on mechanism of dissemination. Ultrastruct Pathol. 2019;43(4-5):154-161 Authors: Massoth LR, Selig MK, Little BP, Chebib I, Kradin RL Abstract Calcifying fibrous pseudotumor (CFP) is a rare, benign soft tissue tumor that may uncommonly arise in the pleura. These tumors can show multifocal dissemination across the pleural surface, but the...
Rare Cancers
Wed Apr 29, 2020 13:21
Isolated lymphomatoid granulomatosis of the central nervous system: A case report and literature review.
Related ArticlesIsolated lymphomatoid granulomatosis of the central nervous system: A case report and literature review. Neuropathology. 2019 Dec;39(6):479-488 Authors: He C, Wang Y, Zhang L, Lu C, Ge W, Zhang Q, Gui Q, Liu R, Yu S Abstract Lymphomatoid granulomatosis (LYG) is an angiocentric and angiodestructive lymphoproliferative disease which can involve multiple organs of the body and is most common in the lungs. Its pathological features are proliferation...
Rare Cancers
Wed Apr 29, 2020 13:21
A rare case of intracranial extra-axial ependymoma.
Related ArticlesA rare case of intracranial extra-axial ependymoma. Ultrastruct Pathol. 2019;43(4-5):216-219 Authors: Fabbri VP, Papa V, Fioravanti A, Messia M, Tallini G, Asioli S, Cenacchi G Abstract Intracranial extra-axial ependymomas (IEAEs) are extremely uncommon tumors and they could have a wide spectrum of clinical and radiological features. Here we report morphological features of an extra-axial ependymoma (radiology, histology and ultrastructural...
Rare Cancers
Wed Apr 29, 2020 13:21
Analysis of PD-L1 expression and T cell infiltration in different molecular subgroups of diffuse midline gliomas.
Related ArticlesAnalysis of PD-L1 expression and T cell infiltration in different molecular subgroups of diffuse midline gliomas. Neuropathology. 2019 Dec;39(6):413-424 Authors: Jha P, Manjunath N, Singh J, Mani K, Garg A, Kaur K, Sharma MC, Raheja A, Suri A, Sarkar C, Suri V Abstract Diffuse midline gliomas (DMGs) are rare and devastating tumors with limited therapeutic options. Programmed death-ligand 1 (PD-L1) expression represents a potential predictive...
Rare Cancers
Wed Apr 29, 2020 13:21
Incidence and Risk Factors for Isolated Esophageal Cancer Recurrence to the Brain.
Related ArticlesIncidence and Risk Factors for Isolated Esophageal Cancer Recurrence to the Brain. Ann Thorac Surg. 2020 02;109(2):329-336 Authors: Nobel TB, Dave N, Eljalby M, Xing X, Barbetta A, Hsu M, Tan KS, Janjigian Y, Bains MS, Sihag S, Jones DR, Molena D Abstract BACKGROUND: Recurrence of esophageal cancer in the brain is rare but associated with a poor prognosis. Identification of risk factors for isolated brain metastasis of esophageal cancer...
Rare Cancers
Wed Apr 29, 2020 13:21
Chondroma of the falx cerebri: A case report and review of literature.
Related ArticlesChondroma of the falx cerebri: A case report and review of literature. Neuropathology. 2019 Dec;39(6):461-466 Authors: Elhakeem AAS, Essa AA, Soliman RK Abstract Chondroma is a benign cartilage-forming tumor which usually occurs in small bones of extremities but occasionally occurs in the brain. Usually, intracranial chondromas originate from skull base; however, chondroma of the falx cerebri is a very rare condition. We here report...
Rare Cancers
Wed Apr 29, 2020 13:21
Gastric cancer during pregnancy: A report on 13 cases and review of the literature with focus on chemotherapy during pregnancy.
Related ArticlesGastric cancer during pregnancy: A report on 13 cases and review of the literature with focus on chemotherapy during pregnancy. Acta Obstet Gynecol Scand. 2020 01;99(1):79-88 Authors: Maggen C, Lok CA, Cardonick E, van Gerwen M, Ottevanger PB, Boere IA, Koskas M, Halaska MJ, Fruscio R, Gziri MM, Witteveen PO, Van Calsteren K, Amant F, International Network on Cancer, Infertility and Pregnancy (INCIP) Abstract INTRODUCTION: Gastric cancer...
Rare Cancers
Wed Apr 29, 2020 13:21
Glioblastoma with tumor-to-tumor metastasis from lung adenocarcinoma.
Related ArticlesGlioblastoma with tumor-to-tumor metastasis from lung adenocarcinoma. Neuropathology. 2019 Dec;39(6):474-478 Authors: Fioravanzo A, Simbolo M, Giampiccolo D, Damante R, Pinna G, Scarpa A, Barresi V Abstract Glioblastoma is a tumor with widely variable morphology. It may rarely show pseudoepithelial components or true epithelial differentiation. Metastasis to glioblastomas have been previously reported, but were unsupported by immunohistochemical...
Rare Cancers
Wed Apr 29, 2020 13:21
Checkpoint kinase 1 is essential for fetal and adult hematopoiesis.
Related ArticlesCheckpoint kinase 1 is essential for fetal and adult hematopoiesis. EMBO Rep. 2019 08;20(8):e47026 Authors: Schuler F, Afreen S, Manzl C, Häcker G, Erlacher M, Villunger A Abstract Checkpoint kinase 1 (CHK1) is critical for S-phase fidelity and preventing premature mitotic entry in the presence of DNA damage. Tumor cells have developed a strong dependence on CHK1 for survival, and hence, this kinase has developed into a promising drug...
Rare Cancers
Wed Apr 29, 2020 13:21

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