Related ArticlesTargeting isocitrate dehydrogenase mutations (IDH) in AML: wielding the double-edged sword of differentiation. Curr Cancer Drug Targets. 2020 Apr 24;: Authors: Becker JS, Fathi AT Abstract The genomic characterization of acute myeloid leukemia (AML) by DNA sequencing has illuminated subclasses of the disease, with distinct driver mutations, that might be responsive to targeted therapies. Approximately 15-23% of AML genomes harbor mutations...
Sat Apr 25, 2020 15:57
Related ArticlesOverexpression of p62 Induces Autophagy and Promotes Proliferation, Migration and Invasion of Nasopharyngeal Carcinoma Cells through Promoting ERK Signaling Pathway. Curr Cancer Drug Targets. 2020 Apr 24;: Authors: Wu Q, Xiang M, Wang K, Chen Z, Long L, Tao Y, Liang Y, Yan Y, Xiao Z, Qiu S, Yi B Abstract BACKGROUND: Increasing evidence has shown that p62 plays an important role in tumorigenesis. However, relatively little is known about...
Sat Apr 25, 2020 15:57
Related ArticlesThe Therapeutic Potential of MEK1/2 inhibitors in the treatment of gynecological cancers: Rational Strategies and Recent Progress. Curr Cancer Drug Targets. 2020 Apr 24;: Authors: Ghanaatgar-Kasbi S, Khazaei M, Rastgar-Moghadam A, Ferns GA, Hassanian SM, Avan A Abstract The mitogen-activated protein kinase (MAPK) pathwayis among the key factors in numerous cellular processes involved in tumorigenesis, suggesting it as a potential therapeutic...
Sat Apr 25, 2020 15:57
The rapid spread of SARS-CoV-2, a novel coronavirus that emerged in late 2019, and the resulting Covid-19 disease has been labeled a Public Health Emergency of International Concern by the World Health Organization. What physicians need to know about transmission, diagnosis, and treatment is the…
Thu Apr 23, 2020 03:00
119 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2020/04/25PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Apr 25, 2020 15:45
3052 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/04/25PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Apr 25, 2020 15:44
To rapidly communicate short reports of innovative responses to Covid-19 around the world, along with a range of current thinking on policy and strategy relevant to the pandemic, the Journal has initiated the Covid-19 Notes series. Treating patients in New York City, the global epicenter of the…
Fri Apr 24, 2020 03:00
Related ArticlesIntraparotid and cervical lymph nodes metastasis in primary parotid gland carcinoma-impact on clinical outcome. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Apr 21;: Authors: Schneider S, Kotowski U, Kadletz L, Brunner M, Stanisz I, Heiduschka G, Lill C Abstract OBJECTIVE: The aim of this study was to investigate the prognostic value of evaluation of intraparotid and cervical lymph node metastases in primary parotid cancer. ...
Sat Apr 25, 2020 15:34
ABSTRACT Acral lentiginous melanoma is a histological subtype of cutaneous melanoma that occurs in the glabrous skin of the palms, soles and in the nail unit. Although in some countries, particularly in Latin America, Africa and Asia, it represents the most frequently diagnosed subtype of the disease, it only represents a small proportion of melanoma cases in European‐descent populations, which is partially why it has not been studied to the same extent as other forms of melanoma. As a result, its...
Fri Apr 24, 2020 22:20
38 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/04/25PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Apr 25, 2020 15:16
Related ArticlesLight activation of cyclometalated ruthenium complexes drives towards caspase 3 dependent apoptosis in gastric cancer cells. J Inorg Biochem. 2020 Mar 28;208:111080 Authors: Solís-Ruiz JA, Barthe A, Riegel G, Saavedra-Díaz RO, Gaiddon C, Le Lagadec R Abstract Polypyridyl ruthenium complexes have been intensively investigated for their remarkable antiproliferative properties and some are currently being tested in clinical trials. Here,...
Sat Apr 25, 2020 15:10
Related ArticlesEfficacy of quality improvement and patient safety workshops for students: a pilot study. BMC Med Educ. 2020 Apr 23;20(1):126 Authors: Shah KP, Goyal S, Ramachandran V, Kohn JR, Go JA, Wiley Z, Moturu A, Namireddy MK, Kumar A, Jacobs RC, Stampfl M, Shah JR, Fu J, Lin WV, Ho B, Wey G, Lin SY, Caruso AC, Gay LJ, Stewart DE, Andrabi S Abstract BACKGROUND: While the Association of American Medical Colleges encourages medical schools to incorporate...
Sat Apr 25, 2020 14:55
Related ArticlesIs individual practice in an immersive and interactive virtual reality application non-inferior to practicing with traditional equipment in learning systematic clinical observation? A randomized controlled trial. BMC Med Educ. 2020 Apr 22;20(1):123 Authors: Berg H, Steinsbekk A Abstract BACKGROUND: The aim was to investigate if individual self-practice of the ABCDE approach (Airways, Breathing, Circulation, Disability, Exposure) in an...
Sat Apr 25, 2020 14:55
Related ArticlesWhen investigating depression and anxiety in undergraduate medical students timing of assessment is an important factor - a multicentre cross-sectional study. BMC Med Educ. 2020 Apr 23;20(1):125 Authors: Thiemann P, Brimicombe J, Benson J, Quince T Abstract BACKGROUND: Symptoms of depression and anxiety experienced by undergraduate medical students have become a prominent concern. Evidence about students' depression and anxiety including...
Sat Apr 25, 2020 14:55
148 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/04/25PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Apr 25, 2020 14:54
Related ArticlesPrevalence of Allergic Rhinitis and Associated Risk Factors in 6 to 12 Years Schoolchildren From Wuhan in Central China: A Cross-sectional Study. Am J Rhinol Allergy. 2020 Apr 23;:1945892420920499 Authors: Tong H, Gao L, Deng Y, Kong Y, Xiang R, Tan L, Tao Z, Xu Y PMID: 32326719 [PubMed - as supplied by publisher]
Sat Apr 25, 2020 14:52
Related ArticlesMedical Liability in Sinus Surgery: A Westlaw Database Analysis From 2000 to 2017. Am J Rhinol Allergy. 2020 Apr 23;:1945892420920479 Authors: Shah SN, Ramirez AV, Haroun KB, Chaaban MR PMID: 32326718 [PubMed - as supplied by publisher]
Sat Apr 25, 2020 14:52
Related ArticlesPrevention of Intra-abdominal Adhesions by Electrical Stimulation. World J Surg. 2020 Apr 23;: Authors: Fakhradiyev IR, Ydyrys A, Timur S, Aygul A, Baimakhan T, Maral Y, Zhandos S, Feril LB Abstract The study investigated the ability of transdermal electric stimulation to prevent the formation of intra-abdominal adhesions in the combination with Seprafilm® (anti-adhesive agent). One hundred and twenty-eight (128) rabbits were subjected...
Sat Apr 25, 2020 14:50
Related ArticlesMajor Variation in the Incidence of Appendicitis Before, During and After Pregnancy: A Population-Based Cohort Study. World J Surg. 2020 Apr 23;: Authors: Moltubak E, Landerholm K, Blomberg M, Redéen S, Andersson RE Abstract BACKGROUND: Previous studies indicate a low incidence of appendicitis in third-trimester pregnancy, suggesting a protecting effect of pregnancy. This large population-based cohort study analyzes the association of...
Sat Apr 25, 2020 14:50
Related ArticlesShould We Consider the Resected Lung Volume in Primary Spontaneous Pneumothorax? World J Surg. 2020 Apr 23;: Authors: Jeon HW, Kim YD, Sim SB Abstract BACKGROUND: Although bullectomy is the most curative treatment in primary spontaneous pneumothorax (PSP), postoperative recurrence is not uncommon. New bulla formation at the staple line is the most common cause of recurrence. However, the mechanism is not known. We believe that the pressure...
Sat Apr 25, 2020 14:50
Related ArticlesComparison of Lobectomy and Total Thyroidectomy in Unilateral Papillary Thyroid Microcarcinoma Patients with Ipsilateral Lateral Lymph Node Metastasis Without Gross Extrathyroidal Extension. World J Surg. 2020 Apr 23;: Authors: Song J, Qiu W, Yan T, Wu B, Guo M, Fan Y, Yang Z Abstract BACKGROUND: Lateral lymph node metastasis (LLNM) occurs in a few of papillary thyroid microcarcinoma (PTMC) cases by the time of diagnosis. Total thyroidectomy...
Sat Apr 25, 2020 14:50
Related ArticlesEarly and Midterm Outcomes of Open and Endovascular Revascularization of Chronic Mesenteric Ischemia. World J Surg. 2020 Apr 23;: Authors: Menges AL, Reutersberg B, Busch A, Salvermoser M, Feith M, Trenner M, Kallmayer M, Zimmermann A, Eckstein HH Abstract BACKGROUND: Revascularization strategies for chronic mesenteric ischemia (CMI) include open (OR) and endovascular (ER) modalities. The primary objective of this study was to analyze...
Sat Apr 25, 2020 14:50
Related ArticlesInvited Commentary: Extrathyroidal Extension on Preoperative Ultrasonography of Thyroid Lesions. World J Surg. 2020 Apr 23;: Authors: Carneiro-Pla D, Javid M PMID: 32328780 [PubMed - as supplied by publisher]
Sat Apr 25, 2020 14:50
Related ArticlesAn ideal biodegradable material for repairing the tympanic membrane perforations following ventilation tube. Int J Pediatr Otorhinolaryngol. 2020 Apr 15;134:110050 Authors: Lou Z PMID: 32330772 [PubMed - as supplied by publisher]
Sat Apr 25, 2020 14:45
Related ArticlesPrevalence and Features of Thyroglossal Duct Cyst on Ultrasonography, According to Radioactive Iodine Therapy: A Single-Center Study. Front Endocrinol (Lausanne). 2020;11:188 Authors: Park JS, Kim DW, Shin GW, Park JY, Lee YJ, Choo HJ, Park HK, Ha TK, Kim DH, Jung SJ, Moon SH, Ahn KJ, Baek HJ Abstract Objective: The relationship between radioactive iodine therapy (RIT) and prevalence of thyroglossal duct cysts (TGDC) on ultrasonography...
Sat Apr 25, 2020 14:39
Related ArticlesUpdates on Thyroid Disease in Rabbits and Guinea Pigs. Vet Clin North Am Exot Anim Pract. 2020 May;23(2):373-381 Authors: DiGeronimo PM, Brandão J Abstract Hyperthyroidism seems to be a rare, but likely underdiagnosed disease of guinea pigs (Cavia porcellus) and rabbits (Oryctolagus cuniculus). Diagnosis is confounded by nonspecific clinical signs, lack of validated assays, and species-specific reference intervals. With increasing...
Sat Apr 25, 2020 14:39
Related ArticlesRisk stratification using a novel genetic classifier including <i>PLEKHS1</i> promoter mutations for differentiated thyroid cancer with distant metastasis. Thyroid. 2020 Apr 23;: Authors: Jung CK, Jung SH, Jeon S, Jeong YM, Kim Y, Lee S, Bae JS, Chung YJ Abstract BACKGROUND: Although most differentiated thyroid cancers (DTCs) have indolent behavior, DTCs with distant metastasis have a poor prognosis. However, there are...
Sat Apr 25, 2020 14:39
Related ArticlesThyroid eye disease with choroidal folds. Orbit. 2020 Apr 23;:1-9 Authors: Tran AQ, Zhang-Nunes SX, Cahill K, Alabiad CR, Shriver EM, Ho T, Weinberg DA, Couch SM, Schlachter DM, Nguyen J, Wester ST Abstract Purpose: To determine the clinical course of patients with chorioretinal folds (CRF) in thyroid eye disease (TED).Methods: A multi-center retrospective case series of patients with TED who developed CRF.Results: Ten patients (17 eyes)...
Sat Apr 25, 2020 14:39
Related ArticlesAssociation of time to initial clinic visit with prolonged recovery in pediatric patients with concussion. J Neurosurg Pediatr. 2020 Apr 24;:1-6 Authors: Eagle SR, Puligilla A, Fazio-Sumrok V, Kegel N, Collins MW, Kontos AP Abstract OBJECTIVE: No studies to date have investigated the role of early clinical care in time to recovery from concussion in a pediatric population. The purpose of this study was to investigate the role of clinic...
Sat Apr 25, 2020 14:38
Related ArticlesResidual thoracolumbar/lumbar curve is related to self-image after posterior spinal fusion for Lenke 1 and 2 curves in adolescent idiopathic scoliosis patients. J Neurosurg Pediatr. 2020 Apr 24;:1-6 Authors: Mimura T, Ikegami S, Kuraishi S, Uehara M, Oba H, Takizawa T, Munakata R, Hatakenaka T, Koseki M, Takahashi J Abstract OBJECTIVE: Although it is well known that major curve severity in adolescent idiopathic scoliosis (AIS) is inversely...
Sat Apr 25, 2020 14:38
Related ArticlesLetter to the Editor. Abdominal pseudocysts and ventriculoperitoneal shunts. J Neurosurg Pediatr. 2020 Apr 24;:1-2 Authors: James HE PMID: 32330893 [PubMed - as supplied by publisher]
Sat Apr 25, 2020 14:38
Related ArticlesLong-term outcomes after surgery for catastrophic epilepsy in infants: institutional experience and review of the literature. J Neurosurg Pediatr. 2020 Apr 24;:1-8 Authors: Ye VC, Shah AH, Sur S, Achua JK, Wang S, Ibrahim GM, Bhatia S, Ragheb J Abstract OBJECTIVE: Uncontrolled epilepsy is associated with serious deleterious effects on the neurological development of infants and has been described as "catastrophic epilepsy." Recently,...
Sat Apr 25, 2020 14:38
Related ArticlesTiming of syrinx reduction and stabilization after posterior fossa decompression for pediatric Chiari malformation type I. J Neurosurg Pediatr. 2020 Apr 24;:1-7 Authors: Chotai S, Chan EW, Ladner TR, Hale AT, Gannon SR, Shannon CN, Bonfield CM, Naftel RP, Wellons JC Abstract OBJECTIVE: The aim of this study was to determine the timeline of syrinx regression and to identify factors mitigating syrinx resolution in pediatric patients with...
Sat Apr 25, 2020 14:38
Related ArticlesThe evolving indications of KD therapy. Epilepsy Res. 2020 Apr 14;163:106340 Authors: Armeno M, Caraballo R Abstract Despite the rapid increase of clinical and basic-science knowledge on ketogenic diet therapies over the past years, it has not always been easy to determine the adequate indications of this treatment. Over the nearly 100 years of use, from being a last resource in the therapeutic algorithm, the diet has become one of the...
Sat Apr 25, 2020 14:38
Related ArticlesNeurocritical care and target immunotherapy for febrile infection-related epilepsy syndrome. Biomed J. 2020 Apr 21;: Authors: Sakuma H, Horino A, Kuki I Abstract Febrile infection-related epilepsy syndrome (FIRES) is an intractable neurological disease characterized by an unexplained refractory status epilepticus triggered by febrile infection. A Consensus definition of FIRES was proposed in 2018, and its clinical features and prognosis...
Sat Apr 25, 2020 14:38
Related ArticlesNeuronal Ceroid Lipofuscinosis type 2: an Australian case series. J Paediatr Child Health. 2020 Apr 24;: Authors: Johnson AM, Mandelstam S, Andrews I, Boysen K, Yaplito-Lee J, Fietz M, Nagarajan L, Rodriguez-Casero V, Ryan MM, Smith N, Scheffer IE, Ellaway C Abstract AIM: Late infantile neuronal ceroid lipofuscinosis type 2 (CLN2) disease is a rare neurodegenerative disorder presenting in children aged 2-4 years with seizures and loss...
Sat Apr 25, 2020 14:38
Related ArticlesEffectiveness and tolerability of lacosamide as add-on therapy in patients with brain tumor-related epilepsy: Results from a prospective, noninterventional study in European clinical practice (VIBES). Epilepsia. 2020 Apr;61(4):647-656 Authors: Rudà R, Houillier C, Maschio M, Reijneveld JC, Hellot S, De Backer M, Chan J, Joeres L, Leunikava I, Glas M, Grant R Abstract OBJECTIVE: To evaluate the effectiveness and tolerability of lacosamide...
Sat Apr 25, 2020 14:38
Related ArticlesEpilepsy Treatment Outcome and Its Predictors among Ambulatory Patients with Epilepsy at Mizan-Tepi University Teaching Hospital, Southwest Ethiopia. Neurol Res Int. 2020;2020:8109858 Authors: Zewudie A, Mamo Y, Feyissa D, Yimam M, Mekonen G, Abdela A Abstract Background: Epilepsy is among the most common neurological disorders which is highly treatable with currently available antiepileptic drugs at a reasonable price. In Ethiopia, despite...
Sat Apr 25, 2020 14:38
Related ArticlesKeeping people with epilepsy safe during the Covid-19 pandemic. Neurology. 2020 Apr 23;: Authors: French JA, Brodie MJ, Caraballo R, Devinsky O, Ding D, Jehi L, Jette N, Kanner A, Modi AC, Newton CR, Patel AA, Pennell PB, Perucca E, Sander JW, Scheffer IE, Singh G, Williams E, Wilmshurst J, Cross JH Abstract OBJECTIVES: To provide information on the impact of the COVID-19 pandemic on people with epilepsy and provide consensus recommendations...
Sat Apr 25, 2020 14:38
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