IJERPH, Vol. 17, Pages 2894: Evidence Supports PA Prescription for Parkinson’s Disease: Motor Symptoms and Non-Motor Features: A Scoping Review International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082894 Authors: Yi-Chen Cheng Chun-Hsien Su Parkinson’s disease (PD) is a prevalent neurodegenerative disorder, which relates to not only motor symptoms, but also cognitive, autonomic, and mood impairments. The literature suggests that pharmacological...
Wed Apr 22, 2020 03:00
IJERPH, Vol. 17, Pages 2882: Environmental and Occupational Risk Factors of Amyotrophic Lateral Sclerosis: A Population-Based Case-Control Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082882 Authors: Tommaso Filippini Marina Tesauro Maria Fiore Carlotta Malagoli Michela Consonni Federica Violi Laura Iacuzio Elisa Arcolin Gea Oliveri Conti Antonio Cristaldi Pietro Zuccarello Elisabetta Zucchi Letizia Mazzini...
Wed Apr 22, 2020 03:00
IJERPH, Vol. 17, Pages 2887: Heavy Metal Uptake of Lettuce and Ryegrass from Urban Waste Composts International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082887 Authors: Remigio Paradelo Antía Villada María Teresa Barral Interest in using urban waste composts as amendments in urban agriculture is growing nowadays. However, concerns about the potential transference of pollutants present in urban waste to the food chain are very relevant when they are...
Wed Apr 22, 2020 03:00
IJERPH, Vol. 17, Pages 2889: The Spatial Distribution Characteristics of Soil Organic Carbon and Its Effects on Topsoil under Different Karst Landforms International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082889 Authors: Xingfu Wang Xianfei Huang Jiwei Hu Zhenming Zhang Karst landforms are widely distributed in Guizhou Province, and the karst terrain is complex. To investigate the spatial distribution characteristics of soil organic carbon (SOC)...
Wed Apr 22, 2020 03:00
IJERPH, Vol. 17, Pages 2880: Noise Exposure and Hearing Loss among Brewery Workers in Lagos, Nigeria
IJERPH, Vol. 17, Pages 2880: Noise Exposure and Hearing Loss among Brewery Workers in Lagos, Nigeria International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082880 Authors: Nino L. Wouters Charlotte I. Kaanen Petronella J. den Ouden Herbert Schilthuis Stefan Böhringer Bas Sorgdrager Richard Ajayi Jan A. P. M. de Laat The health risks of exposure to loud noises are a well-established fact and are widely addressed in modern industries....
Wed Apr 22, 2020 03:00
IJERPH, Vol. 17, Pages 2885: Special Issue on E-Health Services International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082885 Authors: Rolf Wynn Elia Gabarron Jan-Are K. Johnsen Vicente Traver The importance of e-health to citizens, patients, health providers, governments, and other stakeholders is rapidly increasing. E-health services have a range of advantages. For instance, e-health may improve access to services, reduce costs, and improve...
Wed Apr 22, 2020 03:00
IJERPH, Vol. 17, Pages 2879: What Is New about the Exposome? Exploring Scientific Change in Contemporary Epidemiology International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082879 Authors: Stefano Canali In this commentary, I discuss the scientific changes brought by the exposome, asking what is new about this approach and line of research. I place the exposome in a historical perspective, by analyzing the conditions under which the exposome has been conceived,...
Wed Apr 22, 2020 03:00
IJERPH, Vol. 17, Pages 2888: Change in the Mindset of a Paediatric Exercise Physiologist: A Review of Fifty Years Research International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082888 Authors: Kemper In this review, the career of a pediatric exercise physiologist (HCGK) is given over a period of almost 50 years. His research was concentrated on the relationship of physical activity (physical education, sport, and daily physical activity) with health...
Wed Apr 22, 2020 03:00
IJERPH, Vol. 17, Pages 2883: Sleep and Wellbeing, Now and in the Future International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082883 Authors: Chin Moi Chow The processes of sleeping, eating and moving, in concert with cognition and learning, support health and life [...]
Wed Apr 22, 2020 03:00
IJERPH, Vol. 17, Pages 2884: Validity and Reliability of a New Inertial Device for Monitoring Range of Motion at the Pelvis during Sexual Intercourse International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082884 Authors: José M. Oliva-Lozano Isabel Martín-Fuentes José M. Muyor To understand the physical demands of sexual intercourse, it is necessary to monitor the kinematic parameters of this activity using relatively non-invasive technology. The...
Wed Apr 22, 2020 03:00
IJERPH, Vol. 17, Pages 2881: The Effects of Cyanobacterial Bloom Extracts on the Biomass, Chl-a, MC and Other Oligopeptides Contents in a Natural Planktothrix agardhii Population International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082881 Authors: Magdalena Toporowska Hanna Mazur-Marzec Barbara Pawlik-Skowrońska Blooms of the cyanobacterium Planktothrix agardhii are common in shallow, eutrophic freshwaters. P. agardhii may produce hepatotoxic microcystins...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2963: Probing Hexaminolevulinate Mediated PpIX Fluorescence in Cancer Cell Suspensions in the Presence of Chemical Adjuvants International Journal of Molecular Sciences doi: 10.3390/ijms21082963 Authors: Chan Gleadle Vasilev MacGregor Exogenous administration of hexaminolevulinate (HAL) induces fluorescent protoporphyrin IX (PpIX) accumulation preferentially in cancer cells. However, the PpIX fluorescence intensities between noncancer and cancer cells...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2962: Cholesterol Transport in Wild-Type NPC1 and P691S: Molecular Dynamics Simulations Reveal Changes in Dynamical Behavior International Journal of Molecular Sciences doi: 10.3390/ijms21082962 Authors: Nadia Elghobashi-Meinhardt The Niemann–Pick C1 (NPC1) protein is the main protein involved in NPC disease, a fatal lysosomal lipid storage disease. NPC1, containing 1278 amino acids, is comprised of three lumenal domains (N-terminal, middle lumenal, C-terminal)...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2945: Resveratrol in Cancer Patients: From Bench to Bedside International Journal of Molecular Sciences doi: 10.3390/ijms21082945 Authors: Massimiliano Berretta Alessia Bignucolo Raffaele Di Francia Francesco Comello Gaetano Facchini Manuela Ceccarelli Rosario Vincenzo Iaffaioli Vincenzo Quagliariello Nicola Maurea Resveratrol (3,5,4′-trihydroxystilbene) is a natural phytoalexin that accumulates in several vegetables and fruits like...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2964: Gender Predilection in Sporadic Parathyroid Adenomas International Journal of Molecular Sciences doi: 10.3390/ijms21082964 Authors: Yavropoulou Anastasilakis Panagiotakou Kassi Makras Primary hyperparathyroidism is a common endocrinopathy that is mainly caused by benign parathyroid adenomas. The frequency, clinical presentation and complications of the disease show significant differences between genders, with the majority of cases being reported...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2959: O-Vanillin Attenuates the TLR2 Mediated Tumor-Promoting Phenotype of Microglia International Journal of Molecular Sciences doi: 10.3390/ijms21082959 Authors: Triller Bachorz Synowitz Kettenmann Markovic Malignant gliomas are primary brain tumors with poor prognoses. These tumors are infiltrated by brain intrinsic microglia and peripheral monocytes which promote glioma cell invasion. In our previous studies, we discovered that the activation...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2960: Development of Thiazolidinones as Fungal Carbonic Anhydrase Inhibitors International Journal of Molecular Sciences doi: 10.3390/ijms21082960 Authors: Güzel-Akdemir Carradori Grande Demir-Yazıcı Angeli Supuran Akdemir In our efforts to find new and selective thiazolidinone-based anti-Candida agents, we synthesized and tested 26 thiazolidinones against several Candida spp. and Gram-positive and Gram-negative bacteria. The compounds showed...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2921: G2M Cell Cycle Pathway Score as a Prognostic Biomarker of Metastasis in Estrogen Receptor (ER)-Positive Breast Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21082921 Authors: Masanori Oshi Hideo Takahashi Yoshihisa Tokumaru Li Yan Omar M. Rashid Ryusei Matsuyama Itaru Endo Kazuaki Takabe The vast majority of breast cancer death is a result of metastasis. Thus, accurate identification of patients who are likely to have...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2958: Kisspeptin and Testicular Function—Is it Necessary? International Journal of Molecular Sciences doi: 10.3390/ijms21082958 Authors: Sharma Thaventhiran Minhas Dhillo Jayasena The role of kisspeptin in stimulating hypothalamic GnRH is undisputed. However, the role of kisspeptin signaling in testicular function is less clear. The testes are essential for male reproduction through their functions of spermatogenesis and steroidogenesis. Our review...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2954: ERGO: Breaking Down the Wall between Human Health and Environmental Testing of Endocrine Disrupters International Journal of Molecular Sciences doi: 10.3390/ijms21082954 Authors: Henrik Holbech Peter Matthiessen Martin Hansen Gerrit Schüürmann Dries Knapen Marieke Reuver Frédéric Flamant Laurent Sachs Werner Kloas Klara Hilscherova Marc Leonard Jürgen Arning Volker Strauss Taisen Iguchi Lisa Baumann ERGO (EndocRine...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2955: The Sodium Channel B4-Subunits are Dysregulated in Temporal Lobe Epilepsy Drug-Resistant Patients International Journal of Molecular Sciences doi: 10.3390/ijms21082955 Authors: Mariam A. Sheilabi Louise Y. Takeshita Edward J. Sims Francesco Falciani Alessandra P. Princivalle Temporal lobe epilepsy (TLE) is the most common type of partial epilepsy referred for surgery due to antiepileptic drug (AED) resistance. A common molecular target for many...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2957: Graphene Oxide–Based Nanomaterials: An Insight into Retinal Prosthesis International Journal of Molecular Sciences doi: 10.3390/ijms21082957 Authors: Yang Yu Cheng Chung Liu Wu Lin Chen Retinal prosthesis has recently emerged as a treatment strategy for retinopathies, providing excellent assistance in the treatment of age-related macular degeneration (AMD) and retinitis pigmentosa. The potential application of graphene oxide (GO),...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2956: Cutaneous Squamous Cell Carcinoma: From Biology to Therapy International Journal of Molecular Sciences doi: 10.3390/ijms21082956 Authors: Roberto Corchado-Cobos Natalia García-Sancha Rogelio González-Sarmiento Jesús Pérez-Losada Javier Cañueto Cutaneous squamous cell carcinoma (CSCC) is the second most frequent cancer in humans and its incidence continues to rise. Although CSCC usually display a benign clinical behavior, it can be both locally invasive...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2942: The Separation and Characterization of Extracellular Vesicles from Medium Conditioned by Bovine Embryos International Journal of Molecular Sciences doi: 10.3390/ijms21082942 Authors: Krishna Chaitanya Pavani Xiaoyuan Lin Joachim Hamacher Wim Van Den Broeck Liesbeth Couck Luc Peelman An Hendrix Ann Van Soom Extracellular vesicles (EVs) have been identified as one of the communication mechanisms amongst embryos. They are secreted into the...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2937: Endocrine Disrupting Chemicals and Type 1 Diabetes International Journal of Molecular Sciences doi: 10.3390/ijms21082937 Authors: Barbara Predieri Patrizia Bruzzi Elena Bigi Silvia Ciancia Simona F. Madeo Laura Lucaccioni Lorenzo Iughetti Type 1 diabetes (T1D) is the most common chronic metabolic disease in children and adolescents. The etiology of T1D is not fully understood but it seems multifactorial. The genetic background determines the...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2935: Kv1.1 Channelopathies: Pathophysiological Mechanisms and Therapeutic Approaches International Journal of Molecular Sciences doi: 10.3390/ijms21082935 Authors: Maria Cristina D’Adamo Antonella Liantonio Jean-Francois Rolland Mauro Pessia Paola Imbrici Kv1.1 belongs to the Shaker subfamily of voltage-gated potassium channels and acts as a critical regulator of neuronal excitability in the central and peripheral nervous systems. KCNA1 is the only gene...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2953: Interleukin-17 Reduces βENaC via MAPK Signaling in Vascular Smooth Muscle Cells International Journal of Molecular Sciences doi: 10.3390/ijms21082953 Authors: Jeremy W. Duncan Joey P. Granger Michael J. Ryan Heather A. Drummond Degenerin proteins, such as the beta epithelial Na+ channel (βENaC), are essential in the intracellular signaling of pressure-induced constriction, an important vascular smooth muscle cell (VSMC) function. While certain...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2952: Low-Frequency Magnetic Fields (LF-MFs) Inhibit Proliferation by Triggering Apoptosis and Altering Cell Cycle Distribution in Breast Cancer Cells International Journal of Molecular Sciences doi: 10.3390/ijms21082952 Authors: Aoshu Xu Qian Wang Tingting Lin Breast cancer is a common malignancy threatening women’s health around the world. Despite improved treatments for different subtypes of breast tumors that have been put forward, there still...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2947: Crosstalk of lncRNA and Cellular Metabolism and Their Regulatory Mechanism in Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21082947 Authors: Yang-Hsiang Lin The imbalanced regulation of metabolic homeostasis and energy production is highly associated with inflammation, tumor growth, metastasis and cancer progression. Both glycolysis and oxidative phosphorylation maintain metabolic homeostasis and energy production in cells. Long noncoding...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2948: Sex-Specific SARS-CoV-2 Mortality: Among Hormone-Modulated ACE2 Expression, Risk of Venous Thromboembolism and Hypovitaminosis D International Journal of Molecular Sciences doi: 10.3390/ijms21082948 Authors: Sandro La Vignera Rossella Cannarella Rosita A. Condorelli Francesco Torre Antonio Aversa Aldo E. Calogero Severe acute respiratory syndrome coronavirus (SARS-CoV-2) disease (COVID-19) appears to have a higher mortality rate in presence of...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2946: Hydroxyapatite Formation Coexists with Amyloid-like Self-Assembly of Human Amelogenin International Journal of Molecular Sciences doi: 10.3390/ijms21082946 Authors: Jing Zhang Jian Wang Chengwei Ma Junxia Lu Tooth enamel is formed in an extracellular environment. Amelogenin, the major component in the protein matrix of tooth enamel during the developing stage, could assemble into high molecular weight structures, regulating enamel formation. However,...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2944: Aedes albopictus Autophagy-Related Gene 8 (AaAtg8) Is Required to Confer Anti-Bacterial Gut Immunity International Journal of Molecular Sciences doi: 10.3390/ijms21082944 Authors: Chang Eun Kim Ki Beom Park Hye Jin Ko Maryam Keshavarz Young Min Bae BoBae Kim Bharat Bhusan Patnaik Ho Am Jang Yong Seok Lee Yeon Soo Han Yong Hun Jo Autophagy is an important process by which pathogens and damaged or unused organelles are eliminated....
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2949: Crocetin Prevents RPE Cells from Oxidative Stress through Protection of Cellular Metabolic Function and Activation of ERK1/2 International Journal of Molecular Sciences doi: 10.3390/ijms21082949 Authors: Padideh Karimi Ali Gheisari Sylvia J Gasparini Hossein Baharvand Faezeh Shekari Leila Satarian Marius Ader Age-related macular degeneration (AMD) is a leading cause for visual impairment in aging populations with limited established therapeutic...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2950: Multiple Sclerosis Treatment and Melanoma Development International Journal of Molecular Sciences doi: 10.3390/ijms21082950 Authors: Carbone Lacal Messinese De Giglio Pozzilli Persechino Mazzanti Failla Pagnanelli Therapy of multiple sclerosis (MS) with disease-modifying agents such as natalizumab or fingolimod has been associated with the development of cutaneous melanoma. Here we briefly revise literature data and report of...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2943: PACAP Modulates the Autophagy Process in an In Vitro Model of Amyotrophic Lateral Sclerosis International Journal of Molecular Sciences doi: 10.3390/ijms21082943 Authors: D’Amico Maugeri Saccone Federico Cavallaro Reglodi D’Agata Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease of complex etiology leading to motor neuron degeneration. Many gene alterations cause this pathology, including mutation in Cu,...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2951: Roles of Nrf2 in Protecting the Kidney from Oxidative Damage International Journal of Molecular Sciences doi: 10.3390/ijms21082951 Authors: Masahiro Nezu Norio Suzuki Over 10% of the global population suffers from kidney disease. However, only kidney replacement therapies, which burden medical expenses, are currently effective in treating kidney disease. Therefore, elucidating the complicated molecular pathology of kidney disease is an urgent priority for...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2940: Cannabis and Canabidinoids on the Inflammatory Bowel Diseases: Going Beyond Misuse International Journal of Molecular Sciences doi: 10.3390/ijms21082940 Authors: Antonelly Cassio Alves de Carvalho Gabriela Achete de Souza Samylla Vaz de Marqui Élen Landgraf Guiguer Adriano Cressoni Araújo Claudio José Rubira Ricardo de Alvares Goulart Uri Adrian Prync Flato Patricia Cincotto dos Santos Bueno Rogério Leone Buchaim Sandra M. Barbalho ...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2939: Amino-Functionalized Nitrogen-Doped Graphene-Quantum-Dot-Based Nanomaterials with Nitrogen and Amino-Functionalized Group Content Dependence for Highly Efficient Two-Photon Bioimaging International Journal of Molecular Sciences doi: 10.3390/ijms21082939 Authors: Wen-Shuo Kuo Chia-Yuan Chang Keng-Shiang Huang Jui-Chang Liu Yu-Ting Shao Chih-Hui Yang Ping-Ching Wu We fabricated nanomaterials comprising amino-functionalized and nitrogen-doped...
Wed Apr 22, 2020 03:00
IJMS, Vol. 21, Pages 2938: Hemokinin-1 Gene Expression Is Upregulated in Trigeminal Ganglia in an Inflammatory Orofacial Pain Model: Potential Role in Peripheral Sensitization International Journal of Molecular Sciences doi: 10.3390/ijms21082938 Authors: Timea Aczél Angéla Kecskés József Kun Kálmán Szenthe Ferenc Bánáti Susan Szathmary Róbert Herczeg Péter Urbán Attila Gyenesei Balázs Gaszner Zsuzsanna Helyes Kata Bölcskei A large percentage of primary...
Wed Apr 22, 2020 03:00
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