Related ArticlesLeukocyte-mimicking nanovesicles for effective doxorubicin delivery to treat breast cancer and melanoma. Biomater Sci. 2020 Jan 01;8(1):333-341 Authors: Molinaro R, Martinez JO, Zinger A, De Vita A, Storci G, Arrighetti N, De Rosa E, Hartman KA, Basu N, Taghipour N, Corbo C, Tasciotti E Abstract In the last decades, several approaches were developed to design drug delivery systems to address the multiple biological barriers encountered...
Sat Apr 18, 2020 13:09
Related ArticlesThe incidence and relative risk of PD-1/PD-L1 inhibitors-related colitis in non-small cell lung cancer: A meta-analysis of randomized controlled trials. Int Immunopharmacol. 2019 Dec;77:105975 Authors: Lin LL, Lin GF, Luo Q, Chen XQ Abstract BACKGROUND: The programmed cell death-1 (PD-1)/programmed cell death ligand-1 (PD-L1) inhibitors have shown encouraging merits in non-small cell lung cancer (NSCLC) patients, however, they are often...
Sat Apr 18, 2020 13:09
Related ArticlesParathyroid hormone related protein (PTHrP)-mediated hypercalcemia in malignancy associated with anti-PD-1 immune checkpoint inhibitor treatment and related inflammatory reactions. Int Immunopharmacol. 2019 Dec;77:105942 Authors: Deligiorgi MV, Panayiotidis MI, Trafalis DT Abstract Over the last decade, the breakthrough of immune checkpoint inhibitors has revolutionized cancer therapeutics, an enterprise not devoid of a novel constellation...
Sat Apr 18, 2020 13:09
Related ArticlesSurgical and radiosurgical treatment strategies for Cushing's disease. J Neurooncol. 2019 Dec;145(3):403-413 Authors: Bunevicius A, Laws ER, Vance ML, Iuliano S, Sheehan J Abstract INTRODUCTION: Cushing's disease (CD) is rare disorder that should be adequately managed to optimize long-term prognosis. Treatment of CD is multidisciplinary and often includes surgical resection, adjuvant stereotactic radiosurgery (SRS), and medical treatment....
Sat Apr 18, 2020 13:09
Related ArticlesEvaluating pediatric spinal low-grade gliomas: a 30-year retrospective analysis. J Neurooncol. 2019 Dec;145(3):519-529 Authors: Carey SS, Sadighi Z, Wu S, Chiang J, Robinson GW, Ghazwani Y, Liu APY, Acharya S, Merchant TE, Boop FA, Gajjar A, Qaddoumi I Abstract PURPOSE: Most pediatric spinal tumors are low-grade gliomas (LGGs). Characterization of these tumors has been difficult given their heterogeneity and rare incidence. The objective...
Sat Apr 18, 2020 13:09
Related ArticlesAssociation between extent of resection on survival in adult brainstem high-grade glioma patients. J Neurooncol. 2019 Dec;145(3):479-486 Authors: Doyle J, Khalafallah AM, Yang W, Sun Y, Bettegowda C, Mukherjee D Abstract BACKGROUND: Brainstem high-grade gliomas (HGG) are rare lesions with aggressive behavior that pose significant treatment challenges. The operative use of brainstem safe entry zones has made such lesions surgically accessible,...
Sat Apr 18, 2020 13:09
Related ArticlesMalignant Peritoneal Mesothelioma: Patterns of Care and Survival in the Netherlands: A Population-Based Study. Ann Surg Oncol. 2019 Dec;26(13):4222-4228 Authors: de Boer NL, van Kooten JP, Damhuis RAM, Aerts JGJV, Verhoef C, Madsen EVE Abstract BACKGROUND: Malignant peritoneal mesothelioma (MPM) is a rare and aggressive disease. Recently, focus has shifted toward a more aggressive and multimodal treatment approach. This study aimed...
Sat Apr 18, 2020 13:09
Related ArticlesLaser for vascular anomalies: successful outcomes in children. Clin Exp Dermatol. 2020 Mar;45(2):141-146 Authors: Rinaldi G, Batul Syed S Abstract Vascular anomalies can cause both emotional and physical distress to patients, particularly children. The paediatric laser service at Great Ormond Street Hospital (GOSH) treats a range of dermatological conditions including a variety of vascular anomalies, excess hair growth and disfiguring...
Sat Apr 18, 2020 13:09
Related ArticlesTXNDC9 regulates oxidative stress-induced androgen receptor signaling to promote prostate cancer progression. Oncogene. 2020 01;39(2):356-367 Authors: Feng T, Zhao R, Sun F, Lu Q, Wang X, Hu J, Wang S, Gao L, Zhou Q, Xiong X, Dong X, Wang L, Han B Abstract Reactive oxygen species (ROS) and ROS-induced oxidative stress are associated with prostate cancer (PCa) development and castrate-resistant tumor progression. This is in part through...
Sat Apr 18, 2020 13:09
Related ArticlesThin vulvar melanoma: a challenging diagnosis. Dermoscopic features of a case series. Clin Exp Dermatol. 2020 Mar;45(2):187-193 Authors: Vaccari S, Barisani A, Salvini C, Pirola S, Preti EP, Pennacchioli E, Iacobone AD, Patrizi A, Tosti G Abstract BACKGROUND: Vulvar melanoma (VM) is rare and is often diagnosed late. Dermoscopy may aid in its recognition, differentiating VM from other more common vulvar lesions, such as melanosis and...
Sat Apr 18, 2020 13:09
Related ArticlesDyskeratosis Congenita and Oral Cavity Squamous Cell Carcinoma: Report of a Case and Literature Review. J Pediatr Hematol Oncol. 2019 08;41(6):501-503 Authors: Trott KE, Briddell JW, Corao-Uribe D, Powell J, Seecof OM, Levy C, Miller EG, Shah UK Abstract Dyskeratosis congenita is a rare genetic condition of telomerase dysfunction in which patients are at an increased risk of squamous cell carcinoma (SCCa) of the oral cavity. We present...
Sat Apr 18, 2020 13:09
Related ArticlesOverall survival and tumor recurrence after surgical resection for primary malignant chest wall tumors: a single-center, single-surgeon experience. J Orthop Surg (Hong Kong). 2019 May-Aug;27(2):2309499019838296 Authors: Shah AC, Komperda KW, Mavanur AA, Thorpe SW, Weiss KR, Goodman MA Abstract BACKGROUND AND OBJECTIVES: Malignant primary chest wall tumors (PCWTs) comprise a rare group of thoracic tumors with unique anatomical considerations,...
Sat Apr 18, 2020 13:09
Related ArticlesHypopharyngeal Skin Cancer Following Total Laryngectomy and Pectoralis Flap Reconstruction: Case Report and Literature Review. Head Neck Pathol. 2019 Dec;13(4):643-647 Authors: Amin SN, Shinn JR, Tang A, Lewis JS, Mannion K Abstract Although early complications of microvascular free flaps and regional pedicled flaps of the head and neck are well described in the literature, there is relatively limited knowledge regarding their long-term...
Sat Apr 18, 2020 13:09
Related ArticlesCalcifying Epithelial Odontogenic (Pindborg) Tumor in a Child: A Case Report and Literature Review. Head Neck Pathol. 2019 Dec;13(4):580-586 Authors: Fazeli SR, Giglou KR, Soliman ML, Ezzat WH, Salama A, Zhao Q Abstract Calcifying epithelial odontogenic tumor (CEOT) is a rare neoplasm, which accounts for < 1% of all odontogenic tumors. CEOT occurs more frequently in adults with a peak incidence in the 5th decade of life and is extremely...
Sat Apr 18, 2020 13:09
Related ArticlesPrimary Tonsillar Epithelioid Follicular Dendritic Cell Sarcoma: Report of a Rare Case Mimicking Undifferentiated Carcinoma and a Brief Review of the Literature. Head Neck Pathol. 2019 Dec;13(4):606-612 Authors: Wu B, Lim CM, Petersson F Abstract We present a 52 years old male with a left tonsillar follicular dendritic cell sarcoma with prominent epithelioid features that on light microscopical examination bore a striking resemblance...
Sat Apr 18, 2020 13:09
Related ArticlesAdamantinoma-Like Ewing Sarcoma of the Thyroid: A Case Report and Review of the Literature. Head Neck Pathol. 2019 Dec;13(4):618-623 Authors: Morlote D, Harada S, Lindeman B, Stevens TM Abstract Currently considered a variant of Ewing sarcoma, adamantinoma-like Ewing sarcoma is a rare malignancy that shows classic Ewing sarcoma-associated gene fusions but also epithelial differentiation. Here we present the 6th reported case of adamantinoma-like...
Sat Apr 18, 2020 13:09
Related ArticlesPediatric Subcutaneous Panniculitis-like T-Cell Lymphoma With Hemophagocytosis Showing Complete Resolution With the BFM90 Protocol: Case Report and Review of Literature. J Pediatr Hematol Oncol. 2019 08;41(6):478-481 Authors: Singh S, Philip CC, John MJ Abstract Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a distinct subtype of peripheral T-cell lymphoma associated with aggressive clinical behavior. Since its original description,...
Sat Apr 18, 2020 13:09
Related ArticlesSecretory Carcinoma of the Thyroid Gland: Report of a Highly Aggressive Case Clinically Mimicking Undifferentiated Carcinoma and Review of the Literature. Head Neck Pathol. 2019 Dec;13(4):562-572 Authors: Desai MA, Mehrad M, Ely KA, Bishop JA, Netterville J, Aulino JM, Lewis JS Abstract After being described in the salivary glands as a malignancy with features essentially identical to those of the breast, secretory carcinoma (SC) (formerly...
Sat Apr 18, 2020 13:09
Related ArticlesOncocytic Sialolipoma of Parotid Gland: Case Report and Literature Review. Head Neck Pathol. 2019 Dec;13(4):548-553 Authors: Ruangritchankul K, Connor S, Oakley R Abstract Oncocytic sialolipoma is a very rare tumor of which only three cases have been reported. This entity is considered to be a variant of sialolipoma which harbours oncocytic nodules within a well-circumscribed lipomatous mass. We report a parotid mass in 73-year-old...
Sat Apr 18, 2020 13:09
Related ArticlesCiliated HPV-Related Carcinoma: A Diagnostic Challenge on Frozen Section. Head Neck Pathol. 2019 Dec;13(4):727-730 Authors: Navale P, Genden EM, Beasley MB Abstract Oropharyngeal squamous cell carcinomas associated with high risk HPV show a wide morphological spectrum, including papillary, adenosquamous, lymphoepithelioma-like and sarcomatoid. We report an interesting case of ciliated HPV-related carcinoma arising from tonsillar tissue...
Sat Apr 18, 2020 13:09
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