No abstract available
Tue Apr 28, 2020 03:00
No abstract available
Tue Apr 28, 2020 03:00
Ganglion cell-containing pituitary adenomas that are neurofilament protein-positive are the exceedingly rare form of pituitary ganliocytomas. We report a case of a 23-year-old male patient who presented with a clinical picture of acromegaly in addition to raised prolactin level. Histopathology showed areas exhibiting pseudopapillary and solid proliferation of round and monotonous blue cells. The immunohistochemistry showed strong reactivity for synaptophysin and growth hormone and focal reactivity...
Wed Apr 29, 2020 19:35
Bread wheat (Triticum aestivum L.) is one of the world's most important crops. Maintaining wheat yield gains across all of its major production areas is a key target towards underpinning global food security. Brazil is a major wheat producer in South America, generating grain yields of around 6.8 million tonnes per year. Here, we establish and genotype a wheat association mapping resource relevant to contemporary Brazilian wheat breeding programmes. The panel of 558 wheat accessions was genotyped...
Wed Apr 29, 2020 23:13
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c03459
Wed Apr 29, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c02237
Wed Apr 29, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c00755
Wed Apr 29, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c00184
Wed Apr 29, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c02966
Wed Apr 29, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b13309
Wed Apr 29, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c00990
Wed Apr 29, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c02939
Wed Apr 29, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c02721
Wed Apr 29, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c03004
Wed Apr 29, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b13837
Wed Apr 29, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c01104
Wed Apr 29, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c02000
Wed Apr 29, 2020 07:00
Exp Clin Endocrinol DiabetesDOI: 10.1055/a-1105-6332 Context NCI-H295 cells are the most widely used model for adrenal steroidogenesis and adrenocortical carcinoma and have been used for decades in laboratories worldwide. However, reported steroidogenic properties differ considerably. Objective To evaluate heterogeneity of steroidogenesis among NCI-H295 cell strains, clarify...
Wed Apr 29, 2020 02:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00367
Wed Apr 29, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00830
Wed Apr 29, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00844
Wed Apr 29, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00915
Wed Apr 29, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00884
Wed Apr 29, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b05844
Wed Apr 29, 2020 07:00
Laryngo-Rhino-OtolDOI: 10.1055/a-1161-1658 Hintergrund Es wurden die Weiterbildungsassistenten im Fach HNO zur Situation der Weiterbildung und den Arbeitsbedingungen befragt. Die Weiterbildung ist der Schlüssel zur Ausbildung des Nachwuchses im Fachbereich. Methoden Vom 25.04.–01.08.2019 wurden alle 691 bei der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Halschirurgie (DGHNO-KHC) registrierten Ärzte in Weiterbildung in der HNO zur anonymen Teilnahme an einer Online-Umfrage...
Wed Apr 29, 2020 02:00
Laryngo-Rhino-OtolDOI: 10.1055/a-1157-9314 Hintergrund Im aufmerksamen Wachzustand verlängern angenehme Gerüche häufig die Einatmung, während unangenehme Gerüche häufig die Ausatmung verkürzen. Es soll überprüft werden, ob dieses induzierte Atemmuster auch im Schlaf erhalten bleibt. Methodik 23 gesunde normosmische Erwachsene wurden für 1 Nacht polysomnografisch untersucht und dabei entweder mit H2S, Phenylethylalkohol (PEA) oder CO2 über ein Fluss-Olfaktometer randomisiert...
Wed Apr 29, 2020 02:00
In December 2019, an outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was reported in Wuhan, China, and it subsequently spread in many countries around the world. Many efforts have been applied to control and prevent the spread of COVID-19, and many scientific studies have been conducted in a short period of time. Here we present an overview of the viral structure, pathogenesis, diagnosis, and clinical features of COVID-19 based...
Wed Apr 29, 2020 12:35
The number of global COVID-19 infected cases is increased rapidly to exceed 370 thousand. COVID-19 is transmitted between humans through direct contact and touching dirty surfaces. This paper aims to find the similarity between DNA sequences of COVID-19 in different countries, and to compare these sequences with three different diseases [HIV, Hand-Foot-Mouth disease (HFMD), and Cryptococcus]. The study used pairwise distance, maximum likelihood tree, and similarity between amino acid to find the...
Wed Apr 29, 2020 12:35
Cell-surface receptors are the inviters of many potent pathogens that can adjust to any kind of circumstance for their existence. Many of these organisms are highly resistant to the currently existing drugs and mutate to new strains with high levels of pathogenesis, posing life-threatening consequences. Owing to such concerns, antiviral strategies are being assessed based on host cell receptor targeting. Many natural compounds with a tendency to strip off the cell surface receptors are under evaluation....
Wed Apr 29, 2020 12:35
OBJECTIVE: Coronavirus disease 2019 (COVID-19) has officially been declared a pandemic by the World Health Organization (WHO). Radiological examinations, especially computed tomography (CT), play an important role in the fight against COVID-19. A comprehensive and timely review of radiological role in the fight against COVID-19 remains urgent and mandatory. Hence, the aim of this review is to summarize the radiological role in the fight against COVID-19. This review of current studies on COVID-19...
Wed Apr 29, 2020 12:35
At present, SARS-Cov-2 is spread all over the world, becoming a serious threat to people’s health. SARS-Cov-2 has a strong infection, and the mortality rate of severe patients after infection is high, but there is no effective treatment. Mesenchymal stem cells (MSCs) have anti-inflammatory and immunomodulatory functions, which can reduce the occurrence of cytokine storm syndrome and acute respiratory distress syndrome. At the same time, MSCs can reduce the level of pulmonary fibrosis and enhance...
Wed Apr 29, 2020 12:35
OBJECTIVE: Currently, Coronavirus COVID-19 is spreading worldwide very rapidly and its control is very difficult because there is no effective vaccine or drugs available in markets. This virus can infect both animals and people and cause illnesses of the respiratory tract. WHO has declared Coronavirus as pandemic and the whole world is fighting against Coronavirus. Globally, more than 199,478 people have been diagnosed with COVID-19. As of March 18, 2020, more than 167 countries have been affected...
Wed Apr 29, 2020 12:35
OBJECTIVE: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also called COVID-19, has caused a pandemic which has swiftly involved the entire world and raised great public health concerns. The scientific community is actively exploring treatments that would potentially be effective in combating COVID-19. Hydroxychloroquine has been demonstrated to limit the replication of SARS-CoV-2 virus in vitro. In malarial pandemic countries, chloroquine is widely used to treat malaria....
Wed Apr 29, 2020 12:35
On February 1, 2020, China announced a novel coronavirus CoVID-19 outbreak to the public. CoVID-19 was classified as an epidemic by the World Health Organization (WHO). Although the disease was discovered and concentrated in Hubei Province, China, it was exported to all of the other Chinese provinces and spread globally. As of this writing, all plans have failed to contain the novel coronavirus disease, and it has continued to spread to the rest of the world. This study aimed to explore and interpret...
Wed Apr 29, 2020 12:35
OBJECTIVE: The recent outbreak of SARS-CoV-2 greatly involves the resources of the global healthcare system, as it affects newborns, adults, and elders. This infection runs in three major stages: a mild cold-like illness, a moderate respiratory syndrome and a severe acute interstitial pneumonia. SARS-CoV-2 infection seems to have a more benign evolution in children. As a matter of fact, low susceptibility and minor aggressivity have been highlighted in most cases. There are currently no effective...
Wed Apr 29, 2020 12:35
OBJECTIVE: SARS-CoV-2 is responsible for the present coronavirus pandemic and some suggestions were made about its possible artificial origin. We, therefore, compared SARS-CoV-2 with such known viruses that were prepared in the laboratory and other relevant natural strains to estimate their genetic relatedness.MATERIALS AND METHODS: BLAST and clustalW were used to identify and align viral sequences of SARS-CoV-2 to other animal coronaviruses (human, bat, mouse, pangolin) and related artificial constructs....
Wed Apr 29, 2020 12:35
Coronavirus Disease-2019 (COVID-19) caused by SARS-CoV-2 infection has rapidly spread all over the world, in just two months. As of 27 March, globally, 509,164 cases confirmed included 23,335 deaths in approximately 150 countries. Recently, WHO has defined COVID-19 as a global pandemic, and considerable researches have focused on the identification and prevention of SARS-CoV-2. As a result, accumulated publications successively reported their early findings, leading to the constant updating of information,...
Wed Apr 29, 2020 12:35
Congenital pulmonary airway malformations (CPAMs) are abnormalities of the lung arising during development. At our institution the majority of type I infantile CPAMs contain mucinous cell clusters (MCCs). The overlapping histology of MCCs and adult in situ mucinous adenocarcinomas, as well as reports of metastatic mucinous adenocarcinoma arising in CPAMs resected later in childhood raise concerns about the malignant potential of these cells. However, after adequate surgical resection, malignant recurrence...
Tue Apr 28, 2020 03:00
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