Related ArticlesChild After Choking Episode. Ann Emerg Med. 2020 02;75(2):146-170 Authors: Cummins BF PMID: 31959307 [PubMed - indexed for MEDLINE]
Related ArticlesOutcomes of tracheoesophageal puncture in twice-radiated patients. Am J Otolaryngol. 2019 Nov - Dec;40(6):102272 Authors: Clancy K, Sozansky Lujan J, Xia T, Zender C, Maronian N Abstract OBJECTIVE: Previous research has demonstrated the safety of tracheoesophageal puncture voice prosthesis (TEP) placement in radiated patients; however, there is a growing population of twice-radiated patients with limited research on the outcomes of TEP-placement...
Related ArticlesA comparative morphological and histological study of the gastrointestinal tract of four insectivorous bat species: Asellia tridens, Chaerephon pumilus, Nycteris thebaica, Rhinopoma hardwickii. J Morphol. 2019 08;280(8):1106-1117 Authors: Aylward M, Beselaar LC, Alagaili AN, Amor NMS, Mohammed OB, Kotzé SH Abstract Various studies address the morphology of the gastrointestinal tracts (GITs) of insectivorous bat species. However, detailed...
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Abstract Embracing an inter-disciplinary approach grounded on Gärdenfors’ theory of conceptual spaces, we introduce a formal framework to analyse and compare selected theories about technical artefacts present in the literature. Our focus is on design-oriented approaches where both designing and manufacturing activities play a crucial role. Intentional theories, like Kroes’ dual nature thesis, are able to solve disparate problems concerning artefacts but they face both the philosophical...
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Related ArticlesHER2 intratumoral heterogeneity is independently associated with distal metastasis and overall survival in HER2-positive breast carcinomas. Breast Cancer Res Treat. 2020 Apr 25;: Authors: Shen T, Nitta H, Wei L, Parwani AV, Li Z Abstract PURPOSE: Human epidermal growth factor receptor 2 (HER2) intratumoral heterogeneity (ITH) occurs in a subset of breast cancers. Our recent study revealed it as an independent predictive factor for the...
Related ArticlesCorrelation between HER2 Expression and Clinicopathological Features of Breast Cancer: A Cross- Sectional Study in Vietnam. Asian Pac J Cancer Prev. 2020 Apr 01;21(4):1135-1142 Authors: Dang Cong T, Nguyen Thanh T, Nguyen Phan QA, Hoang Thi AP, Nguyen Tran BS, Nguyen Vu QH Abstract BACKGROUND: HER2 is the target of the therapeutic agents which are used to treat HER2-positive breast cancer. Reports have shown that the HER2 oncogene expression...
Related ArticlesIntratumoral CD103-positive tumor-infiltrating lymphocytes are associated with favorable prognosis in patients with triple-negative breast cancer. Histopathology. 2020 Apr 25;: Authors: Park MH, Kwon SY, Choi JE, Gong G, Bae YK Abstract AIMS: Cluster of differentiation 103 (CD103), a marker of tissue resident memory T cell, is expressed on subsets of CD8+ T lymphocytes. We investigated the prognostic significance of CD103+ intraepithelial...
Related ArticlesNanobody-targeted photodynamic therapy induces significant tumor regression of trastuzumab-resistant HER2-positive breast cancer, after a single treatment session. J Control Release. 2020 Apr 21;: Authors: Deken MM, Kijanka MM, Hernández IB, Slooter MD, de Bruijn HS, van Diest PJ, van Bergen En Henegouwen PMP, Lowik CWGM, Robinson DJ, Vahrmeijer AL, Oliveira S Abstract RATIONALE: A substantial number of breast cancer patients with an...
Related ArticlesHER3 targeting with an antibody-drug conjugate bypasses resistance to anti-HER2 therapies. EMBO Mol Med. 2020 Apr 24;:e11498 Authors: Gandullo-Sánchez L, Capone E, Ocaña A, Iacobelli S, Sala G, Pandiella A Abstract Despite impressive clinical benefit obtained with anti-HER2-targeted therapies, in advances stages, especially in the metastatic setting, HER2-positive tumors remain incurable. Therefore, it is important to develop novel strategies...
Related ArticlesPreclinical Targeted α- and β--Radionuclide Therapy in HER2-Positive Brain Metastasis Using Camelid Single-Domain Antibodies. Cancers (Basel). 2020 Apr 21;12(4): Authors: Puttemans J, Dekempeneer Y, Eersels JL, Hanssens H, Debie P, Keyaerts M, Windhorst AD, van der Aa F, Lecocq Q, Breckpot K, Morgenstern A, Bruchertseifer F, Lahoutte T, Devoogdt N, D'Huyvetter M Abstract HER2-targeted therapies have drastically improved the outcome for...
Related ArticlesNew ADC Shrinks HER2-Positive Tumors. Cancer Discov. 2019 09;9(9):1151-1152 Authors: Abstract A phase I trial reported positive results for an antibody-drug conjugate that targets HER2-positive tumors. Trastuzumab duocarmazine, which kills tumor cells by causing DNA damage, induced partial responses in 33% of patients whose tumors were resistant to the approved antibody-drug conjugate trastuzumab emtansine. The drug caused fatigue, neutropenia,...
The Multifaceted Nature of Tumor Microenvironment in Breast Carcinomas. Pathobiology. 2020 Apr 23;87(2):1-18 Authors: Annaratone L, Cascardi E, Vissio E, Sarotto I, Chmielik E, Sapino A, Berrino E, Marchiò C Abstract Heterogeneity in breast carcinomas can be appreciated at various levels, from morphology to molecular alterations, and there are well-known genotypic-phenotypic correlations. Clinical decision-making is strictly focused on the evaluation...
Evaluating Trastuzumab in the treatment of HER2 positive breast cancer. Histol Histopathol. 2020 Apr 23;:18221 Authors: Jaques R, Xu S, Matsakas A Abstract The transmembrane oncoprotein HER2 is encoded by ERBB2 gene and overexpressed in around 20% of invasive breast cancers. It can be specifically targeted by Trastuzumab (Herceptin®), a humanised IgG1 antibody. Trastuzumab has been regarded as one of the most effective therapeutic drugs targeted to HER2...
Prospective, randomized, single-blinded, multi-center phase II trial of two HER2 peptide vaccines, GP2 and AE37, in breast cancer patients to prevent recurrence. Breast Cancer Res Treat. 2020 Apr 22;: Authors: Brown TA, Mittendorf EA, Hale DF, Myers JW, Peace KM, Jackson DO, Greene JM, Vreeland TJ, Clifton GT, Ardavanis A, Litton JK, Shumway NM, Symanowski J, Murray JL, Ponniah S, Anastasopoulou EA, Pistamaltzian NF, Baxevanis CN, Perez SA, Papamichail M, Peoples GE ...
Development of a risk scoring system for evaluating the prognosis of patients with Her2-positive breast cancer. Cancer Cell Int. 2020;20:121 Authors: Gao C, Zhuang J, Li H, Liu C, Zhou C, Liu L, Feng F, Sun C, Wu J Abstract Background: As one of the many breast cancer subtypes, human epidermal growth factor receptor 2 (Her2)-positive breast cancer has higher invasiveness and poor prognosis, although the advent of anti-Her2 drugs has brought good news...
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Objective: Previous reports proposed prelemniscal radiations (Raprl) as a target to treat motor symptoms of Parkinson’s disease, and this was found particularly effective to control rest and postural tremor. However, tremor of other etiologies has been seldom treated with deep brain stimulation or ablation in this target. We present a series of such cases successfully treated by Raprl radiofrequency (RF) lesions. Material and Methods: Six patients with predominant unilateral tremor on the right arm:...
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22 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2020/04/27PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
63 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2020/04/26PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
130 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2020/04/25PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
130 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2020/04/25PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
109 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2020/04/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
109 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2020/04/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Related ArticlesConsensus on resectability in N3 head and neck squamous cell carcinomas: GETTEC recommendations. Oral Oncol. 2020 Apr 23;106:104733 Authors: Carsuzaa F, Gorphe P, Vergez S, Malard O, Fakhry N, Righini C, Philouze P, Lasne-Cardon A, Gallet P, Tonnerre D, Bozec A, de Mones E, Baujat B, Laccourreye L, Babin E, Dufour X, Thariat J Abstract BACKGROUND: Among patients with T0-2 N3 head and neck squamous cell carcinomas (HNSCC), those undergoing...
Related ArticlesCharacterization and implications of the lingual process of the sphenoid bone: a cadaveric and radiographic study. Int Forum Allergy Rhinol. 2020 Apr 25;: Authors: Li L, London NR, Chen X, Prevedello DM, Carrau RL Abstract BACKGROUND: The surgical significance of the lingual process of the sphenoid bone (LPSB) has not been sufficiently addressed. The purpose of this study was to describe the anatomical details of the LPSB in relation...
Related ArticlesHybrid antero-lateral transcondylar approach to the clivus: a laboratory investigation and case illustration. Acta Neurochir (Wien). 2020 Apr 25;: Authors: Di Carlo DT, Voormolen EH, Passeri T, Champagne PO, Penet N, Bernat AL, Froelich S Abstract BACKGROUND: Surgical treatment of lesions involving the ventral craniovertebral junction (CVJ) and the lower clivus, traditionally involved complex lateral or transoral approaches to the skull...
Related ArticlesTransmucosal Pterygomaxillary Separation in the Le Fort I Osteotomy. Plast Reconstr Surg. 2020 May;145(5):1262-1265 Authors: Susarla SM, Ettinger RE, Egbert MA Abstract The Le Fort I osteotomy is a versatile operation for correction of developmental, congenital, and posttraumatic deformities of the lower midface. One of the challenges of the osteotomy is pterygomaxillary separation, with the potential for unfavorable fractures to the...
Related ArticlesEndoscopic Anterior Skull Base Reconstruction: A Meta-Analysis and Systematic Review of Graft Type. World Neurosurg. 2020 Apr 21;: Authors: Abiri A, Abiri P, Goshtasbi K, Lehrich BM, Sahyouni R, Hsu FP, Cadena G, Kuan EC Abstract OBJECTIVE: The influence of graft type (non-autologous versus autologous) on surgical outcomes in endoscopic anterior skull base (EASB) reconstruction is not well-understood. This review systematically evaluated...
Related ArticlesMorbidity in the postoperative follow-up of endoscopic anterior skull base surgery. Braz J Otorhinolaryngol. 2020 Apr 11;: Authors: Rezende GL, Neto ORM, Kückelhaus SAS Abstract INTRODUCTION: Endoscopic access to the sellar region by videoendoscopy shows a low rate of surgical complications, with findings that indicate risk factors for reducing morbidities during and after the postoperative period. OBJECTIVE: To evaluate, over...
Related ArticlesThe Effects of Lateral Crural Tensioning with an Articulated Alar Rim Graft Versus Lateral Crural Strut Graft on Nasal Function. Facial Plast Surg Aesthet Med. 2020 Apr 23;: Authors: Kondo M, Orgain C, Alvarado R, Marcells GN, Harvey RJ Abstract Importance: Nasal valve dysfunction can be addressed by various valve reinforcement techniques. There is no consensus on which technique is most efficacious. Objective: To evaluate lateral crural...
Vertebrobasilar Artery Encasement by Skull Base Chordomas: Surgical Outcome and Management Strategies. Oper Neurosurg (Hagerstown). 2020 Apr 23;: Authors: Champagne PO, Passeri T, Jabre R, Bernat AL, Voormolen EH, Froelich S Abstract BACKGROUND: Vascular encasement by skull base chordomas can increase surgical risk and hinder completeness of resection. However, the evidence behind this remains anecdotic. OBJECTIVE: To give a better portrayal...
Surgical Management of Skull Base Osteoradionecrosis in the Cancer Population - Treatment Outcomes and Predictors of Recurrence: A Case Series. Oper Neurosurg (Hagerstown). 2020 Apr 23;: Authors: Habib A, Hanasono MM, DeMonte F, Haider A, Breshears JD, Nader ME, Gidley PW, Su SY, Hanna EY, Raza SM Abstract BACKGROUND: Skull base osteoradionecrosis (ORN) is a challenging treatment-related complication sometimes seen in patients with cancer. Although ORN...
In Reply: Precautions for Endoscopic Transnasal Skull Base Surgery During the COVID-19 Pandemic. Neurosurgery. 2020 Apr 23;: Authors: Patel ZM, Fernandez-Miranda J, Hwang PH, Nayak JV, Dodd RL, Sajjadi H, Jackler RK PMID: 32323725 [PubMed - as supplied by publisher]
Langerhan's cell Histiocytosis of Sphenoid Sinus causing Vision Loss: A Case Report. JNMA J Nepal Med Assoc. 2019 Jul-Aug;57(218):281-284 Authors: Mani S, Thomas R, Mathew R, Michael R Abstract Langerhan's cell histiocytosis is an uncontrolled proliferation of dendritic cells. The involvement of skull base is rare. Variable clinical presentation and multi organ involvement often warrant a multidisciplinary approach for a successful diagnosis. We are...
Analysis of anatomical variation of the inclination of lamellas attached to the skull base and its correlation with the anterior ethmoidal artery floating in the ethmoid sinus for use in endoscopic sinus surgery. Surg Radiol Anat. 2020 Apr 22;: Authors: Takeda T, Kajiwara R, Omura K, Otori N, Wada K Abstract PURPOSE: Attention to the inclination of lamellas attached to the skull base, including the basal lamella of the middle turbinate, facilitates the...
Microbiotyping the Sinonasal Microbiome. Front Cell Infect Microbiol. 2020;10:137 Authors: Bassiouni A, Paramasivan S, Shiffer A, Dillon MR, Cope EK, Cooksley C, Ramezanpour M, Moraitis S, Ali MJ, Bleier BS, Callejas C, Cornet ME, Douglas RG, Dutra D, Georgalas C, Harvey RJ, Hwang PH, Luong AU, Schlosser RJ, Tantilipikorn P, Tewfik MA, Vreugde S, Wormald PJ, Caporaso JG, Psaltis AJ Abstract This study offers a novel description of the sinonasal microbiome,...
A Case of Tuberculum Sellae Chordoid Meningioma Treated via Extended Endoscopic Endonasal Trans-sphenoidal Surgery. NMC Case Rep J. 2020 Apr;7(2):53-56 Authors: Yagi C, Yamamuro S, Ozawa Y, Yoshimura S, Sumi K, Yoshino A Abstract A 68-year-old female was admitted to our hospital with right-sided hemianopsia. Magnetic resonance imaging (MRI) demonstrated a well-enhanced tuberculum sellae region tumor. The patient underwent surgical tumor resection via...
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Related ArticlesOne-stage free transfer of latissimus dorsi-serratus anterior combined muscle flap with dual innervation for smile reanimation in established facial paralysis. J Plast Reconstr Aesthet Surg. 2020 Jan 31;: Authors: Watanabe Y, Yamamoto T, Hirai R, Sasaki R, Agawa K, Akizuki T Abstract Microneurovascular free muscle transfer is the gold-standard surgical procedure for the reanimation of established facial paralysis. However, the innervation...
Related ArticlesThe use of cadaveric fascia lata in single-stage implant-based breast reconstruction: A two-center experience. J Plast Reconstr Aesthet Surg. 2020 Apr 15;: Authors: Schettini AV, Servaes M, Berners A, Lafosse A, Fosseprez P PMID: 32327375 [PubMed - as supplied by publisher]
Related ArticlesEarly nasal reconstruction after skin-preserving excision of squamous cell carcinoma of the nasal vestibule. J Plast Reconstr Aesthet Surg. 2020 Mar 15;: Authors: Federspil PA, Plinkert PK, Zaoui K Abstract Surgery for early-stage squamous cell carcinoma of the nasal vestibule (SCCNV) may lead to facial disfigurement. We wanted to investigate if skin-preserving excision of SCCNV with reconstruction is oncologically, aesthetically, and...
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