Cancers, Vol. 12, Pages 1065: Nelfinavir Inhibits the TCF11/Nrf1-Mediated Proteasome Recovery Pathway in Multiple Myeloma Cancers doi: 10.3390/cancers12051065 Authors: Fassmannová Sedlák Sedláček Špička Grantz Šašková Proteasome inhibitors are the backbone of multiple myeloma therapy. However, disease progression or early relapse occur due to development of resistance to the therapy. One important cause of resistance to proteasome inhibition is the so-called...
Sat Apr 25, 2020 03:00
Cancers, Vol. 12, Pages 1071: Role of Calcium Signaling in Prostate Cancer Progression: Effects on Cancer Hallmarks and Bone Metastatic Mechanisms Cancers doi: 10.3390/cancers12051071 Authors: Juan A. Ardura Luis Álvarez-Carrión Irene Gutiérrez-Rojas Verónica Alonso Advanced prostate cancers that progress to tumor metastases are often considered incurable or difficult to treat. The etiology of prostate cancers is multi-factorial. Among other factors, de-regulation of...
Sat Apr 25, 2020 03:00
Cancers, Vol. 12, Pages 1067: Prognostic Value of SDF-1α Expression in Patients with Esophageal Squamous Cell Carcinoma Receiving Esophagectomy Cancers doi: 10.3390/cancers12051067 Authors: Yen-Hao Chen Shau-Hsuan Li Hung-I Lu Chien-Ming Lo Stromal cell-derived factor-1α (SDF-1α) is a chemokine that has been reported to be involved in tumor progression in several malignancies. This study aimed to evaluate the crucial role of SDF-1α in patients...
Sat Apr 25, 2020 03:00
Cancers, Vol. 12, Pages 1069: Post-Treatment HPV Surface Brushings and Risk of Relapse in Oropharyngeal Carcinoma Cancers doi: 10.3390/cancers12051069 Authors: Kofler Borena Dudas Innerhofer Dejaco Steinbichler Widmann von Laer Riechelmann Human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC) is a distinct subtype of head and neck cancer. Here, we investigated how frequently brushing remained high-risk (hr)-HPV...
Sat Apr 25, 2020 03:00
Cancers, Vol. 12, Pages 1070: Novel Oncolytic Virus Armed with Cancer Suicide Gene and Normal Vasculogenic Gene for Improved Anti-Tumor Activity Cancers doi: 10.3390/cancers12051070 Authors: Jeong Yoo Here, we developed a novel oncolytic vaccinia virus (NOV) with the dual advantages of cancer selectivity and normal vessel reconstructive activity by replacing the viral thymidine kinase (vTk) and vaccinia growth factor (VGF) genes with genes encoding TNF-related apoptosis-inducing...
Sat Apr 25, 2020 03:00
Cancers, Vol. 12, Pages 1066: Sirtuins’ Deregulation in Bladder Cancer: SIRT7 Is Implicated in Tumor Progression through Epithelial to Mesenchymal Transition Promotion Cancers doi: 10.3390/cancers12051066 Authors: Sara Monteiro-Reis Ana Lameirinhas Vera Miranda-Gonçalves Diana Felizardo Paula C. Dias Jorge Oliveira Inês Graça Céline S. Gonçalves Bruno M. Costa Rui Henrique Carmen Jerónimo Sirtuins are emerging players in cancer biology and...
Sat Apr 25, 2020 03:00
Cancers, Vol. 12, Pages 1068: Oncobiosis and Microbial Metabolite Signaling in Pancreatic Adenocarcinoma Cancers doi: 10.3390/cancers12051068 Authors: Borbála Kiss Edit Mikó Éva Sebő Judit Toth Gyula Ujlaki Judit Szabó Karen Uray Péter Bai Péter Árkosy Pancreatic adenocarcinoma is one of the most lethal cancers in both men and women, with a median five-year survival of around 5%. Therefore, pancreatic adenocarcinoma represents an unmet medical need....
Sat Apr 25, 2020 03:00
Cancers, Vol. 12, Pages 1064: The Progressive Mutagenic Effects of Acidic Bile Refluxate in Hypopharyngeal Squamous Cell Carcinogenesis: New Insights Cancers doi: 10.3390/cancers12051064 Authors: Sasaki Doukas Costa Vageli Cancers of the laryngopharynx represent the most devastating of the head and neck malignancies and additional risk factors are now epidemiologically linked to this disease. Using an in vivo model (Mus musculus C57Bl/6J), we provide novel evidence...
Sat Apr 25, 2020 03:00
Cancers, Vol. 12, Pages 1072: Solving the Time- and Frequency-Multiplexed Problem of Constrained Radiofrequency Induced Hyperthermia Cancers doi: 10.3390/cancers12051072 Authors: Kuehne Oberacker Waiczies Niendorf Targeted radiofrequency (RF) heating induced hyperthermia has a wide range of applications, ranging from adjunct anti-cancer treatment to localized release of drugs. Focal RF heating is usually approached using time-consuming nonconvex optimization procedures...
Sat Apr 25, 2020 03:00
Cancers, Vol. 12, Pages 1063: Endogenously-Activated Ultrasmall-in-Nano Therapeutics: Assessment on 3D Head and Neck Squamous Cell Carcinomas Cancers doi: 10.3390/cancers12051063 Authors: Melissa Santi Ana Katrina Mapanao Domenico Cassano Ylea Vlamidis Valentina Cappello Valerio Voliani Negative or positive HPV-associated Head and Neck Squamous Cell Carcinomas (HNSCCs) are high recurrence neoplasms usually resulting in a poor prognosis, mainly due to metastasis...
Sat Apr 25, 2020 03:00
Cancers, Vol. 12, Pages 1062: FGF2 Induces Resistance to Nilotinib through MAPK Pathway Activation in KIT Mutated Melanoma Cancers doi: 10.3390/cancers12051062 Authors: Pauline Tétu Julie Delyon Jocelyne André Coralie Reger de Moura Malak Sabbah Ghanem E Ghanem Maxime Battistella Samia Mourah Céleste Lebbé Nicolas Dumaz KIT is a bona fide oncogene in a subset of melanoma and, ex vivo, KIT inhibitors are very efficient at killing KIT-mutant melanoma...
Sat Apr 25, 2020 03:00
Cancers, Vol. 12, Pages 1061: The Clinical Impact of Low-Volume Lymph Nodal Metastases in Early-Stage Cervical Cancer: The Senticol 1 and Senticol 2 Trials Cancers doi: 10.3390/cancers12051061 Authors: Benedetta Guani Vincent Balaya Laurent Magaud Fabrice Lecuru Patrice Mathevet Background: With the development of the sentinel node technique in early-stage cervical cancer, it is imperative to define the clinical significance of micrometastases (MICs) and isolated...
Sat Apr 25, 2020 03:00
Cancers, Vol. 12, Pages 1060: HPV Involvement in the Tumor Microenvironment and Immune Treatment in Head and Neck Squamous Cell Carcinomas Cancers doi: 10.3390/cancers12051060 Authors: Jérôme R. Lechien Géraldine Descamps Imelda Seminerio Sonia Furgiuele Didier Dequanter Francois Mouawad Cécile Badoual Fabrice Journe Sven Saussez Head and neck squamous cell carcinomas (HNSCC) are one of the most prevalent cancers worldwide. Active human papillomavirus...
Sat Apr 25, 2020 03:00
Cancers, Vol. 12, Pages 1058: The Prognostic Value of the Detection of Microbial Translocation in the Blood of Colorectal Cancer Patients Cancers doi: 10.3390/cancers12041058 Authors: Ippokratis Messaritakis Konstantinos Vogiatzoglou Konstantina Tsantaki Agapi Ntretaki Maria Sfakianaki Asimina Koulouridi John Tsiaoussis Dimitrios Mavroudis John Souglakos Dysbiosis has been associated with various diseases and is of major health importance. Dysbiosis...
Fri Apr 24, 2020 03:00
Cancers, Vol. 12, Pages 1057: Unique Role of Histone Methyltransferase PRDM8 in the Tumorigenesis of Virus-Negative Merkel Cell Carcinoma Cancers doi: 10.3390/cancers12041057 Authors: Elias Orouji Wiebke K. Peitsch Azadeh Orouji Roland Houben Jochen Utikal Merkel cell carcinoma (MCC) is a deadly skin cancer, and about 80% of its cases have been shown to harbor integrated Merkel polyomavirus in the tumor cell genome. Viral oncoproteins expressed in the tumor cells...
Fri Apr 24, 2020 03:00
Cancers, Vol. 12, Pages 1056: Reduced Tumorigenicity of Mouse ES Cells and the Augmented Anti-Tumor Therapeutic Effects under Parg Deficiency Cancers doi: 10.3390/cancers12041056 Authors: Yuki Sonoda Yuka Sasaki Akemi Gunji Hidenori Shirai Tomonori Araki Shoji Imamichi Takae Onodera Anna-Margareta Rydén Masatoshi Watanabe Jun Itami Takuya Honda Kazuto Ashizawa Kazuhiko Nakao Mitsuko Masutani PolyADP-ribosylation is a post-translational...
Fri Apr 24, 2020 03:00
Cancers, Vol. 12, Pages 1059: Incidence of Occult Lymph Node Metastasis in Primary Larynx Squamous Cell Carcinoma, by Subsite, T Classification and Neck Level: A Systematic Review Cancers doi: 10.3390/cancers12041059 Authors: Alvaro Sanabria Jatin P. Shah Jesus E. Medina Kerry D. Olsen K. Thomas Robbins Carl E. Silver Juan P. Rodrigo Carlos Suárez Andrés Coca-Pelaz Ashok R. Shaha Antti A. Mäkitie Alessandra Rinaldo Remco de Bree Primož...
Fri Apr 24, 2020 03:00
Cancers, Vol. 12, Pages 1055: Cut-Off Analysis of CTC Change under Systemic Therapy for Defining Early Therapy Response in Metastatic Breast Cancer Cancers doi: 10.3390/cancers12041055 Authors: Thomas M. Deutsch Stefan Stefanovic Manuel Feisst Chiara Fischer Fabian Riedel Carlo Fremd Christoph Domschke Klaus Pantel Andreas D. Hartkopf Marc Sutterlin Sara Y. Brucker Andreas Schneeweiss Markus Wallwiener Detection of circulating tumor...
Fri Apr 24, 2020 03:00
Cancers, Vol. 12, Pages 1054: ALK Inhibitors-Induced M Phase Delay Contributes to the Suppression of Cell Proliferation Cancers doi: 10.3390/cancers12041054 Authors: Sirajam Munira Ryuzaburo Yuki Youhei Saito Yuji Nakayama Anaplastic lymphoma kinase (ALK), a receptor-type tyrosine kinase, is involved in the pathogenesis of several cancers. ALK has been targeted with small molecule inhibitors for the treatment of different cancers, but absolute success remains elusive....
Fri Apr 24, 2020 03:00
Cancers, Vol. 12, Pages 1052: Overexpression of Canonical Prefoldin Associates with the Risk of Mortality and Metastasis in Non-Small Cell Lung Cancer Cancers doi: 10.3390/cancers12041052 Authors: Xenia Peñate Juan Manuel Praena-Fernández Pedro Romero Pareja María del Valle Enguix-Riego Laura Payán-Bravo Begoña Vieites Lourdes Gomez-Izquierdo Javier Jaen Olasolo Eleonor Rivin del Campo Jose Carlos Reyes Sebastián Chávez Jose Luis Lopez Guerra...
Fri Apr 24, 2020 03:00
Cancers, Vol. 12, Pages 1053: Self-Collection for Cervical Screening Programs: From Research to Reality Cancers doi: 10.3390/cancers12041053 Authors: David Hawkes Marco H. T. Keung Yanping Huang Tracey L. McDermott Joanne Romano Marion Saville Julia M. L. Brotherton In 2018, there were an estimated 570,000 new cases of cervical cancer globally, with most of them occurring in women who either had no access to cervical screening, or had not participated in...
Fri Apr 24, 2020 03:00
Cancers, Vol. 12, Pages 1051: Radiomics-Based Outcome Prediction for Pancreatic Cancer Following Stereotactic Body Radiotherapy Cancers doi: 10.3390/cancers12041051 Authors: Elsa Parr Qian Du Chi Zhang Chi Lin Ahsan Kamal Josiah McAlister Xiaoying Liang Kyle Bavitz Gerard Rux Michael Hollingsworth Michael Baine Dandan Zheng (1) Background: Radiomics use high-throughput mining of medical imaging data to extract unique information and predict...
Fri Apr 24, 2020 03:00
The 2019 Consultation Conference on the molecular pathology of urogenital cancers was organized by the International Society of Urological Pathology (ISUP) to have an understanding of the current use of molecular-genetic markers and to make recommendations on their application in prostate, bladder, renal, testicular, and penile cancer. This brief introductory article describes the organization of this conference and provides its rationale and main findings. Conflicts of Interest and Source of...
Tue Mar 31, 2020 03:00
No abstract available
Tue Mar 31, 2020 03:00
Publication date: Available online 27 April 2020Source: Academic RadiologyAuthor(s): Shantanu Warhadpande, Minhaj S. Khaja, Saher S. Sabri
Mon Apr 27, 2020 18:22
Publication date: Available online 24 April 2020Source: Academic RadiologyAuthor(s): Liping Yang, Shaodong Cao, Wei Liu, Tianzuo Wang, Hanshan Xu, Chao Gao, Lingbo Zhang, Kezheng Wang
Sat Apr 25, 2020 18:30
Publication date: Available online 24 April 2020Source: Academic RadiologyAuthor(s): Christopher J Burke, Soterios Gyftopoulos
Fri Apr 24, 2020 18:19
Publication date: Available online 25 April 2020Source: Brain Research BulletinAuthor(s): Nandkishor Kotagale, Rupali Deshmukh, Madhura Dixit, Rajshree Fating, Milind Umekar, Brijesh Taksande
Mon Apr 27, 2020 18:20
Publication date: June 2020Source: Photodiagnosis and Photodynamic Therapy, Volume 30Author(s): Thamer Almohareb, Nawaf Alhamoudi, Modhi Al Deeb, Mohammed S. Bin-Shuwaish, Sameer A Mokeem, Syed Saad Shafqat, Fahim Vohra, Tariq Abduljabbar
Mon Apr 27, 2020 18:18
Publication date: Available online 25 April 2020Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Julia J. Shen, Gregor B.E. Jemec, Maiken C. Arendrup, Ditte Marie L. Saunte
Sat Apr 25, 2020 13:49
Publication date: Available online 23 April 2020Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Mohamed Hashem, Ahmed A. El-Hejazi, Muhammad Omar Niaz, Omar Alsadon, Bader M. Alolayani, Hassan Fouad
Fri Apr 24, 2020 17:34
Publication date: Available online 23 April 2020Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Gnanatheepam Einstein, Kanniyappan Udayakumar, Dornadula Koteeswaran, Prakasarao Aruna, Singaravelu Ganesan
Fri Apr 24, 2020 17:34
Publication date: Available online 23 April 2020Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Márcia Braz, Diana Salvador, Ana T.P.C. Gomes, Mariana Q. Mesquita, M. Amparo F. Faustino, M. Graça P.M.S. Neves, Adelaide Almeida
Fri Apr 24, 2020 17:34
Abstract There are a number of psychophysical and electrophysiological measures that are correlated with SGN density in animal models, and these same measures can be performed in humans with cochlear implants (CIs). Thus, these measures are potentially applicable in humans for estimating the condition of the neural population (so called “neural health” or “cochlear health”) at individual sites along the electrode array and possibly adjusting the stimulation strategy in the CI...
Mon Apr 27, 2020 03:00
Publication date: Available online 25 April 2020Source: Revista Española de Medicina Nuclear e Imagen MolecularAuthor(s): A. Niñerola-Baizán, P. Aguiar, M.N. Cabrera-Martín, C. Vigil, A. Gómez-Grande, C. Lorenzo, S. Rubí, P. Sopena, V. Camacho, por el Grupo de Neuroimagen SEMNIM
Mon Apr 27, 2020 18:15
Publication date: Available online 25 April 2020Source: Acta Otorrinolaringológica EspañolaAuthor(s): Davide Soloperto, Andrea Sacchetto, Luca Gazzini, Daniele Marchioni
Mon Apr 27, 2020 18:15
Background. Acute pancreatitis (AP) is a life-threatening disease caused by a variety of factors, and once it progresses to severe acute pancreatitis, the prognosis is poor. The purpose of this study was to investigate the diagnostic value of the neutrophil-lymphocyte ratio (NLR) for predicting the severity of acute pancreatitis. Materials and Methods. We searched the databases of PubMed, EMBASE, Web of Science, and Cochrane Library to identify eligible studies using the NLR to predict the severity...
Mon Apr 27, 2020 09:35
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου