Related ArticlesWhole Exome Sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target. Haematologica. 2020 Apr 23;: Authors: Larose H, Prokoph N, Matthews JD, Schlederer M, Högler S, Alsulami AF, Ducray SP, Nuglozeh E, Fazaludeen FMS, Elmouna A, Ceccon M, Mologni L, Gambacorti-Passerini C, Hoefler G, Lobello C, Pospisilova S, Janikova A, Woessmann W, Damm-Welk C, Zimmermann M, Federova...
Sat Apr 25, 2020 14:41
Related ArticlesMolecular Targets Beyond the Big 3. Thorac Surg Clin. 2020 May;30(2):157-164 Authors: Reckamp KL Abstract Lung cancer is a heterogeneous genomic disease. Smoking remains the primary cause. Genetic susceptibility and environmental exposures are responsible for 10% to 15% of cases. Targeted therapies improve survival in patients with tumors with oncogenic drivers. It is critical to expand our understanding of genetic alterations in...
Sat Apr 25, 2020 14:41
Related ArticlesNeoadjuvant treatments in patients with high-risk resectable stage III/IV melanoma. Expert Rev Anticancer Ther. 2020 Apr 23;: Authors: Spagnolo F, Croce E, Boutros A, Tanda E, Cecchi F, Mascherini M, Solari N, Cafiero F, Queirolo P Abstract Introduction: In recent years, the introduction of targeted therapy and immunotherapy into clinical practice has radically changed the management of advanced melanoma. More recently, these treatments...
Sat Apr 25, 2020 14:41
Related ArticlesReal-world treatment patterns in patients with advanced (stage III-IV) ovarian cancer in the USA and Europe. Future Oncol. 2020 Apr 24;: Authors: Hall JP, Chang J, Moon R, Higson O, Byrne K, Doherty JP, Cappelleri JC Abstract Aim: To analyze real-world data relating to treatment decision-making in stage III-IV ovarian cancer (OC). Materials & methods: Real world data were collected from a survey of physicians and their patients...
Sat Apr 25, 2020 14:41
Related ArticlesDeep learning in fracture detection: a narrative review. Acta Orthop. 2020 04;91(2):215-220 Authors: Kalmet PHS, Sanduleanu S, Primakov S, Wu G, Jochems A, Refaee T, Ibrahim A, Hulst LV, Lambin P, Poeze M Abstract Artificial intelligence (AI) is a general term that implies the use of a computer to model intelligent behavior with minimal human intervention. AI, particularly deep learning, has recently made substantial strides in perception...
Sat Apr 25, 2020 13:40
Related ArticlesHuman Endometrial Microbiota at Term of Normal Pregnancies. Genes (Basel). 2019 11 26;10(12): Authors: Leoni C, Ceci O, Manzari C, Fosso B, Volpicella M, Ferrari A, Fiorella P, Pesole G, Cicinelli E, Ceci LR Abstract The endometrium is a challenging site for metagenomic analysis due to difficulties in obtaining uncontaminated samples and the limited abundance of the bacterial population. Indeed, solid correlations between endometrial...
Sat Apr 25, 2020 13:40
Related ArticlesSolitary fibrous tumor: a case series identifying pathological adverse factors-implications for risk stratification and classification. Virchows Arch. 2020 Apr;476(4):597-607 Authors: Machado I, Morales GN, Cruz J, Lavernia J, Giner F, Navarro S, Ferrandez A, Llombart-Bosch A Abstract Solitary fibrous tumors (SFTs) are a rare type of mesenchymal lesion in which specific clinicopathologic factors have been related to patient outcome....
Sat Apr 25, 2020 13:40
Pitfalls and novel experimental approaches to optimize microbial interventions for chemotherapy-induced gastrointestinal mucositis. Curr Opin Support Palliat Care. 2020 Apr 21;: Authors: da Silva Ferreira AR, Wardill HR, Tissing WJE, Harmsen HJM Abstract PURPOSE OF REVIEW: There is a growing number of studies implicating gut dysbiosis in mucositis development. However, few studies have shed light on the causal relationship limiting translational...
Fri Apr 24, 2020 13:15
Taboo Topics in Adolescent and Young Adult Oncology: Strategies for Managing Challenging but Important Conversations Central to Adolescent and Young Adult Cancer Survivorship. Am Soc Clin Oncol Educ Book. 2020 Mar;40:1-15 Authors: Perez GK, Salsman JM, Fladeboe K, Kirchhoff AC, Park ER, Rosenberg AR Abstract Research on adolescents and young adults (AYAs) with cancer has flourished over the past decade, underscoring the unique medical and psychosocial...
Fri Apr 24, 2020 13:15
DNA methylation‑regulated miR‑155‑5p depresses sensitivity of esophageal carcinoma cells to radiation and multiple chemotherapeutic drugs via suppression of MAP3K10. Oncol Rep. 2020 Mar 06;: Authors: Luo W, Zhang H, Liang X, Xia R, Deng H, Yi Q, Lv L, Qian L Abstract Radiotherapy and chemotherapy are two major treatment options for esophageal carcinoma, and heterogeneous treatment effects are observed in the clinical setting to provide an overall...
Fri Apr 24, 2020 13:15
The impact of the coronavirus pandemic on the management of cancer patients in Lebanon: a single institutional experience. Future Oncol. 2020 Apr 23;: Authors: Kattan C, Badreddine H, Rassy E, Kourie HR, Kattan J PMID: 32323581 [PubMed - as supplied by publisher]
Fri Apr 24, 2020 13:15
What the oncologist needs to know about COVID-19 infection in cancer patients. Future Oncol. 2020 Apr 23;: Authors: Rassy E, Khoury-Abboud RM, Ibrahim N, Kattan C, Assi T, Kattan J PMID: 32323577 [PubMed - as supplied by publisher]
Fri Apr 24, 2020 13:15
Patterns and Covariates of Benefit Finding in Young Black Breast Cancer Survivors: A Longitudinal, Observational Study. Psychooncology. 2020 Apr 22;: Authors: Conley CC, Small BJ, Christie J, Hoogland AI, Augusto BM, Garcia JD, Pal T, Vadaparampil ST Abstract OBJECTIVE: To examine the patterns and covariates of benefit finding over time among young Black breast cancer (BC) survivors. METHODS: Black women (N=305) with invasive BC diagnosed...
Fri Apr 24, 2020 13:15
Artificial Intelligence in radiotherapy: state of the art and future directions. Med Oncol. 2020 Apr 22;37(6):50 Authors: Francolini G, Desideri I, Stocchi G, Salvestrini V, Ciccone LP, Garlatti P, Loi M, Livi L Abstract Recent advances in computing capability allowed the development of sophisticated predictive models to assess complex relationships within observational data, described as Artificial Intelligence. Medicine is one of the several fields...
Fri Apr 24, 2020 13:15
Advances and perspectives of dendritic cell-based active immunotherapies in follicular lymphoma. Cancer Immunol Immunother. 2020 Apr 22;: Authors: Cox MC, Lapenta C, Santini SM Abstract Follicular lymphoma (FL) is a remarkably immune-responsive malignancy, which is still considered incurable. As, standard immunochemotherapy is complex, toxic and not curative, improvement in FL care is now a crucial topic in hemato-oncology. Recently, we and others...
Fri Apr 24, 2020 13:15
Glymphatic clearance of simulated silicon dispersion in mouse brain analyzed by laser induced breakdown spectroscopy. Heliyon. 2020 Apr;6(4):e03702 Authors: Khan MS, Kumar R, Manno SHC, Ahmed I, Lun Law AW, Cruces RR, Ma V, Cho WC, Cheng SH, Lau C Abstract Silicon-based devices, such as neural probes, are increasingly used as electrodes for receiving electrical signals from neural tissue. Neural probes used chronically have been known to induce inflammation...
Fri Apr 24, 2020 13:15
RBFOX1 Regulates the Permeability of the Blood-Tumor Barrier via the LINC00673/MAFF Pathway. Mol Ther Oncolytics. 2020 Jun 26;17:138-152 Authors: Shen S, Yang C, Liu X, Zheng J, Liu Y, Liu L, Ma J, Ma T, An P, Lin Y, Cai H, Wang D, Li Z, Zhao L, Xue Y Abstract The blood-tumor barrier limits the delivery of therapeutic drugs to brain tumor tissues. Selectively opening the blood-tumor barrier is considered crucial for effective chemotherapy of glioma....
Fri Apr 24, 2020 13:15
Real world outcomes in platinum sensitive relapsed ovarian, fallopian tube, or peritoneal cancer treated in routine clinical practice in the United Kingdom prior to poly-ADP ribose polymerase inhibitors. Int J Gynecol Cancer. 2020 Apr 21;: Authors: Lord R, Rauniyar J, Morris T, Condon O, Jones R, Miller R, Hall M, Lofts F, Glasspool RM, Hudson E Abstract INTRODUCTION: The introduction of poly-ADP ribose polymerase inhibitors in ovarian cancer has...
Fri Apr 24, 2020 13:15
Trends in place of death in a small developing country: a population-level study using death certificate data. J Epidemiol Community Health. 2020 Apr 22;: Authors: Jennings N, Chambaere K, Deliens L, Cohen J Abstract BACKGROUND: Valuable information for planning future end-of-life care (EOLC) services and care facilities can be gained by studying trends in place of death (POD). Scarce data exist on the POD in small developing countries. This study...
Fri Apr 24, 2020 13:15
Current radiotherapy techniques in NSCLC: challenges and potential solutions. Expert Rev Anticancer Ther. 2020 Apr 22;: Authors: Giaj-Levra N, Borghetti P, Bruni A, Ciammella P, Cuccia F, Fozza A, Franceschini D, Scotti V, Vagge S, Alongi F Abstract Introduction: Radiotherapy is an important therapeutic strategy in the management of non-small cell lung cancer (NSCLC). In recent decades, technological implementations and the introduction of image...
Fri Apr 24, 2020 13:15
Related ArticlesContraceptive utilization and counseling among breast cancer survivors. J Cancer Surviv. 2019 06;13(3):438-446 Authors: Mody SK, Gorman JR, Oakley LP, Layton T, Parker BA, Panelli D Abstract PURPOSE: To explore contraceptive counseling and utilization among breast cancer survivors. METHODS: We enrolled reproductive-aged women with a history of breast cancer for a cross-sectional study. Participants were recruited via the Athena...
Fri Apr 24, 2020 13:15
Related ArticlesHeterogeneous multiple kernel learning for breast cancer outcome evaluation. BMC Bioinformatics. 2020 Apr 23;21(1):155 Authors: Yu X, Gong X, Jiang H Abstract BACKGROUND: Breast cancer is one of the common kinds of cancer among women, and it ranks second among all cancers in terms of incidence, after lung cancer. Therefore, it is of great necessity to study the detection methods of breast cancer. Recent research has focused on using gene...
Sat Apr 25, 2020 15:34
Related ArticlesOn Sackin's original proposal: the variance of the leaves' depths as a phylogenetic balance index. BMC Bioinformatics. 2020 Apr 23;21(1):154 Authors: M Coronado T, Mir A, Rosselló F, Rotger L Abstract BACKGROUND: The Sackin indexS of a rooted phylogenetic tree, defined as the sum of its leaves' depths, is one of the most popular balance indices in phylogenetics, and Sackin's paper (Syst Zool 21:225-6, 1972) is usually cited as the source...
Sat Apr 25, 2020 15:34
DeepSuccinylSite: a deep learning based approach for protein succinylation site prediction. BMC Bioinformatics. 2020 Apr 23;21(Suppl 3):63 Authors: Thapa N, Chaudhari M, McManus S, Roy K, Newman RH, Saigo H, Kc DB Abstract BACKGROUND: Protein succinylation has recently emerged as an important and common post-translation modification (PTM) that occurs on lysine residues. Succinylation is notable both in its size (e.g., at 100 Da, it is one of the larger...
Fri Apr 24, 2020 14:58
Nanopore basecalling from a perspective of instance segmentation. BMC Bioinformatics. 2020 Apr 23;21(Suppl 3):136 Authors: Zhang YZ, Akdemir A, Tremmel G, Imoto S, Miyano S, Shibuya T, Yamaguchi R Abstract BACKGROUND: Nanopore sequencing is a rapidly developing third-generation sequencing technology, which can generate long nucleotide reads of molecules within a portable device in real-time. Through detecting the change of ion currency signals during...
Fri Apr 24, 2020 14:58
Dual graph convolutional neural network for predicting chemical networks. BMC Bioinformatics. 2020 Apr 23;21(Suppl 3):94 Authors: Harada S, Akita H, Tsubaki M, Baba Y, Takigawa I, Yamanishi Y, Kashima H Abstract BACKGROUND: Predicting of chemical compounds is one of the fundamental tasks in bioinformatics and chemoinformatics, because it contributes to various applications in metabolic engineering and drug discovery. The recent rapid growth of the amount...
Fri Apr 24, 2020 14:58
TooT-T: discrimination of transport proteins from non-transport proteins. BMC Bioinformatics. 2020 Apr 23;21(Suppl 3):25 Authors: Alballa M, Butler G Abstract BACKGROUND: Membrane transport proteins (transporters) play an essential role in every living cell by transporting hydrophilic molecules across the hydrophobic membranes. While the sequences of many membrane proteins are known, their structure and function is still not well characterized and understood,...
Fri Apr 24, 2020 14:58
119 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2020/04/25PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Apr 25, 2020 13:46
147 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2020/04/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri Apr 24, 2020 15:59
147 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2020/04/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri Apr 24, 2020 13:59
Metastatic Lung Cancer Presenting as Monocular Blindness and Panhypopituitarism Secondary to a Pituitary Metastasis. Am J Case Rep. 2020 Apr 23;21:e920948 Authors: Sheahan KH, Huffman GC, DeWitt JC, Gilbert MP Abstract BACKGROUND Sellar masses are most commonly pituitary adenomas, however, about 1% of surgical resected pituitary lesions are found to be metastatic disease. It is hard to distinguish pituitary adenomas from metastatic disease. The most...
Fri Apr 24, 2020 13:29
Related ArticlesVertebral Artery Sacrifice Versus Skeletonization in the Setting of Cervical Spine Tumor Resection: Case Series. World Neurosurg. 2020 Apr 21;: Authors: Westbroek EM, Pennington Z, Ehresman J, Ahmed AK, Gailloud P, Sciubba DM Abstract OBJECT: Tumors of the cervical spine often encase one or both vertebral arteries (VA), presenting the treating surgeon with the dilemma of whether to sacrifice or skeletonize the artery. Here we propose...
Sat Apr 25, 2020 15:21
Related ArticlesSevere radiation necrosis refractory to surgical resection in patients with melanoma and brain metastases managed with ipilimumab/nivolumab and brain-directed stereotactic radiation therapy. World Neurosurg. 2020 Apr 21;: Authors: Shi DD, Arnaout O, Bi WL, Buchbinder EI, Cagney DN, Insco ML, Liu D, Schoenfeld JD, Aizer AA Abstract BACKGROUND: The use of targeted therapies and immune checkpoint inhibitors has drastically changed the management...
Sat Apr 25, 2020 15:21
Related ArticlesEndoscopic Anterior Skull Base Reconstruction: A Meta-Analysis and Systematic Review of Graft Type. World Neurosurg. 2020 Apr 21;: Authors: Abiri A, Abiri P, Goshtasbi K, Lehrich BM, Sahyouni R, Hsu FP, Cadena G, Kuan EC Abstract OBJECTIVE: The influence of graft type (non-autologous versus autologous) on surgical outcomes in endoscopic anterior skull base (EASB) reconstruction is not well-understood. This review systematically evaluated...
Sat Apr 25, 2020 15:21
Related ArticlesIMPACT OF EARLY RE-OPERATION ON THE PROGNOSIS OF PATIENTS OPERATED ON FOR GLIOBLASTOMA. World Neurosurg. 2020 Apr 21;: Authors: Troya-Castilla M, Kaen A, Márquez-Rivas FJ, Cossio PI, Díaz FR, Narros Gimenez JL, Gonzalez-Pombo M, Cancela P, Fernández-Nogueras MS, Arráez MÁ Abstract INTRODUCTION: The prognosis for patients with glioblastoma depends particularly on the degree of tumour resection. Patients with tumour remnants in post-surgical...
Sat Apr 25, 2020 15:21
Related ArticlesSimultaneous Treatment of Petroclival Meningiomas and the Trigeminal Nerve with Gamma Knife Radiosurgery for Tumor-Related Trigeminal Neuralgia. World Neurosurg. 2020 Apr 21;: Authors: Mureb MC, Dastazirgada Y, Benjamin C, Golfinos JG, Kondziolka D Abstract BACKGROUND: Some petroclival meningiomas cause trigeminal nerve compression leading to disabling trigeminal neuralgia. Tumor resection and nerve decompression can offer pain relief...
Sat Apr 25, 2020 15:21
Related ArticlesPrimary brain stem angiosarcoma mimicking cavernous malformation. World Neurosurg. 2020 Apr 21;: Authors: Lee C, Shin YS, Choi JH Abstract BACKGROUND: Cerebral angiosarcoma is an extremely rare malignant tumor that originates from vascular endothelial cells of the brain or meninges. Especially, primary brain stem angiosarcoma has not been reported. CASE DESCRIPTION: A 64-year-old man presented with left subjective weakness, hypesthesia,...
Sat Apr 25, 2020 15:21
Related ArticlesSinus Pericranii Complicated by Hydrocephalus. Case Report and Literature Review. World Neurosurg. 2020 Apr 21;: Authors: Almujaiwel N, Alsager G, Almubarak A, Ajlan A PMID: 32330617 [PubMed - as supplied by publisher]
Sat Apr 25, 2020 15:21
Related ArticlesAcute-on-chronic vertex epidural hematoma with diastasis of the sagittal suture in an adult: a case report. World Neurosurg. 2020 Apr 21;: Authors: Klepinowski T, Kawalec P, Larysz M, Sagan L Abstract BACKGROUND: Vertex epidural hematoma (VEDH) is a rare intracranial mass constituting roughly 2,5% of all epidural hematomas. Bleeding usually derives from the superior sagittal sinus and presentation is often acute, seldom chronic. Fractures...
Sat Apr 25, 2020 15:21
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