Related ArticlesThe Effect of NNK, A Tobacco Smoke Carcinogen, on the miRNA and Mismatch DNA Repair Expression Profiles in Lung and Head and Neck Squamous Cancer Cells. Cells. 2020 Apr 21;9(4): Authors: Doukas SG, Vageli DP, Lazopoulos G, Spandidos DA, Sasaki CT, Tsatsakis A Abstract Tobacco smoking is a common risk factor for lung cancer and head and neck cancer. Molecular changes such as deregulation of miRNA expression have been linked to tobacco...
Sat Apr 25, 2020 14:31
Related ArticlesMulticlass classification of autofluorescence images of oral cavity lesions based on quantitative analysis. PLoS One. 2020;15(2):e0228132 Authors: Jeng MJ, Sharma M, Chao TY, Li YC, Huang SF, Chang LB, Chow L Abstract BACKGROUND: Oral cancer is one of the most common diseases globally. Conventional oral examination and histopathological examination are the two main clinical methods for diagnosing oral cancer early. VELscope is an oral...
Sat Apr 25, 2020 13:00
Related ArticlesDesigning artificial senses: steps from physiology to clinical implementation. Swiss Med Wkly. 2019 May 20;149:w20061 Authors: Pérez Fornos A, Van de Berg R, Sommerhalder J, Guinand N Abstract Our senses are the main information channels through which we perceive and interact with the world. Consequently, the physical and social functioning of patients suffering from severe sensory disabilities is limited on several levels. This has...
Sat Apr 25, 2020 13:00
Penalized maximum-likelihood reconstruction for improving limited-angle artifacts in a dedicated head and neck PET system. Phys Med Biol. 2020 Apr 23;: Authors: Zhang H, Wang Y, Qi J, Abbaszadeh S Abstract Positron emission tomography (PET) suffers from limited spatial resolution in current head and neck cancer management. We are building a dual-panel high-resolution PET system to aid the detection of tumor involvement in small lymph nodes (<...
Fri Apr 24, 2020 13:22
SmartProbe: a bioimpedance sensing system for head and neck cancer tissue detection. Physiol Meas. 2020 Apr 23;: Authors: Cheng Z, Carobbio ALC, Soggiu L, Migliorini M, Guastini L, Mora F, Fragale M, Ascoli A, Africano S, Caldwell D, Canevari FRM, Parrinello G, Peretti G, Mattos LS Abstract This study presents SmartProbe, an electrical bioimpedance (EBI) sensing system based on a concentric needle electrode (CNE). The system allows the use commercial...
Fri Apr 24, 2020 13:22
CD44 and associated markers in oral rinses and tissues from oral and oropharyngeal cancer patients. Oral Oncol. 2020 Apr 20;106:104720 Authors: Cohen ER, Reis IM, Gomez-Fernandez C, Smith D, Pereira L, Freiser ME, Marotta G, Thomas GR, Sargi ZB, Franzmann EJ Abstract OBJECTIVES: Oral and oropharyngeal squamous cell carcinoma (OOPSCC) is a debilitating disease. Salivary rinses contain soluble tumor markers including CD44 (solCD44) and total protein...
Fri Apr 24, 2020 13:22
Endoscopic laryngopharyngeal surgery for hypopharyngeal lesions. Oral Oncol. 2020 Apr 20;106:104655 Authors: Kishimoto Y, Tateya I, Funakoshi M, Miyamoto SI, Muto M, Omori K Abstract OBJECTIVES: Transoral approaches for laryngeal/pharyngeal malignancies have been widely accepted as minimally invasive treatment options; however, hypopharyngeal lesions treated by transoral surgery have rarely been reported due to the difficulties in visualizing the...
Fri Apr 24, 2020 13:22
Placebo effects in allergen immunotherapy - an EAACI Task Force Position Paper. Allergy. 2020 Apr 23;: Authors: Pfaar O, Agache I, Bergmann KC, Bindslev-Jensen C, Bousquet J, Creticos PS, Devillier P, Durham SR, Hellings P, Kaul S, Kleine-Tebbe J, Klimek L, Jacobsen L, Jutel M, Muraro A, Papadopoulos NG, Rief W, Scadding GK, Schedlowski M, Shamji MH, Sturm G, van Ree R, Vidal C, Vieths S, Wedi B, Gerth van Wijk R, Frew AJ Abstract The placebo (Latin...
Fri Apr 24, 2020 13:22
Surgical Management of Skull Base Osteoradionecrosis in the Cancer Population - Treatment Outcomes and Predictors of Recurrence: A Case Series. Oper Neurosurg (Hagerstown). 2020 Apr 23;: Authors: Habib A, Hanasono MM, DeMonte F, Haider A, Breshears JD, Nader ME, Gidley PW, Su SY, Hanna EY, Raza SM Abstract BACKGROUND: Skull base osteoradionecrosis (ORN) is a challenging treatment-related complication sometimes seen in patients with cancer. Although...
Fri Apr 24, 2020 13:22
National representative analysis of unilateral hearing loss and hearing aid usage in South Korea. PLoS One. 2020;15(4):e0232112 Authors: Lee SA, Kang HT, Lee YJ, Lee JD, Kim BG Abstract A definitive study on the prevalence of adult unilateral hearing loss and hearing aid rehabilitation is lacking in Korea. The purpose of our study was to investigate the prevalence of adult unilateral hearing loss and the factors associated with hearing aid use in...
Fri Apr 24, 2020 13:22
Associations among smoking, MGMT hypermethylation, TP53-mutations, and relapse in head and neck squamous cell carcinoma. PLoS One. 2020;15(4):e0231932 Authors: Matsuda S, Mafune A, Kohda N, Hama T, Urashima M Abstract BACKGROUND: Epigenetic silencing of the O6-methylguanine-DNA methyltransferase (MGMT) DNA repair enzyme via promoter hypermethylation (hmMGMT) may increase mutations in the TP53 oncosuppressor gene and contribute to carcinogenesis....
Fri Apr 24, 2020 13:22
Masking Effects in the Perception of Multiple Simultaneous Talkers in Normal-Hearing and Cochlear Implant Listeners. Trends Hear. 2020 Jan-Dec;24:2331216520916106 Authors: Chen B, Shi Y, Zhang L, Sun Z, Li Y, Gopen Q, Fu QJ PMID: 32324486 [PubMed - as supplied by publisher]
Fri Apr 24, 2020 13:22
Diagnosis and Management of Squamous Cell Carcinoma of Unknown Primary in the Head and Neck: ASCO Guideline. J Clin Oncol. 2020 Apr 23;:JCO2000275 Authors: Maghami E, Ismaila N, Alvarez A, Chernock R, Duvvuri U, Geiger J, Gross N, Haughey B, Paul D, Rodriguez C, Sher D, Stambuk HE, Waldron J, Witek M, Caudell J Abstract PURPOSE: To provide evidence-based recommendations to practicing physicians and other health care providers on the diagnosis and...
Fri Apr 24, 2020 13:22
[New information for the clinical detection of COVID-19 virus infection and options for protection of healthcare workers in the head and neck region]. Orv Hetil. 2020 Apr 01;161(17):660-666 Authors: Antal M, Szabó RM, Juhász Z, Vereb T, Piffkó J Abstract The coronavirus disease (COVID-19), which presumably started in China at the end of 2019 and became a pandemic, affects all segments of the health care system worldwide, including Hungary. As healthcare...
Fri Apr 24, 2020 13:22
[Eccrine carcinoma: a diagnostic pitfall]. Ned Tijdschr Geneeskd. 2020 Mar 19;164: Authors: Moonen HPFX, Koot RAC, Hoven-Gondrie ML Abstract BACKGROUND: The eccrine carcinoma is a rare form of skin adnexal malignancy, usually presenting as a locally invasive, solitary lesion in the head and neck region. Histopathologically and immunohistochemically, eccrine carcinomas are difficult to differentiate from cutaneous metastases of breast carcinomas....
Fri Apr 24, 2020 13:22
Combination of RERG and ZNF671 methylation rates in ccfDNA: a novel biomarker for screening of nasopharyngeal carcinoma. Cancer Sci. 2020 Apr 23;: Authors: Xu Y, Zhao W, Mo Y, Ma N, Midorikawa K, Kobayashi H, Hiraku Y, Oikawa S, Zhang Z, Huang G, Takeuchi K, Murata M Abstract Nasopharyngeal carcinoma (NPC) is a prevalent malignancy in Southeast Asia, hence, identifying easily detectable biomarkers for NPC screening is essential for better diagnosis...
Fri Apr 24, 2020 13:22
Study of Rocuronium-Sugammadex as an Alternative to Succinylcholine-Cisatracurium in Microlaryngeal Surgery. Laryngoscope. 2020 Apr 23;: Authors: Aragón-Benedí C, Visiedo-Sánchez S, Pascual-Bellosta A, Ortega-Lucea S, Fernández-Liesa R, Martínez-Ubieto J, Research Group in Anesthesia, Resuscitation AND Perioperative Medicine of Aragón Health Research Institute (IIS Aragón) Abstract Microlaryngeal surgery (ML) is a short procedure that requires a...
Fri Apr 24, 2020 13:22
What is the Optimal Timing of Computed Tomography Imaging to Objectively Confirm Chronic Rhinosinusitis? Laryngoscope. 2020 Apr 23;: Authors: Yim MT, Tan BK, Nathan CO, Orlandi RR PMID: 32324291 [PubMed - as supplied by publisher]
Fri Apr 24, 2020 13:22
The Nasal Swell Body and Septal Perforation Repair. Laryngoscope. 2020 Apr 23;: Authors: Ghorab S, Taylor CM, Bansberg SF Abstract OBJECTIVES: To review our experience with secondary surgery for persistent nasal obstruction following successful septal perforation repair and describe the potential contribution of the nasal swell body (NSB) to obstruction. STUDY DESIGN: Retrospective chart review. METHODS: IRB-approved retrospective...
Fri Apr 24, 2020 13:22
The Importance of Including Otolaryngologists With Geriatric-Specific Training in Research on Older Patients Undergoing Head and Neck Surgery-Reply. JAMA Otolaryngol Head Neck Surg. 2020 Apr 23;: Authors: Rich JT, Fancy T PMID: 32324232 [PubMed - as supplied by publisher]
Fri Apr 24, 2020 13:22
Association Between Hearing Loss and Postural Instability in Older Korean Adults. JAMA Otolaryngol Head Neck Surg. 2020 Apr 23;: Authors: Bang SH, Jeon JM, Lee JG, Choi J, Song JJ, Chae SW Abstract Importance: Hearing loss is one of the most frequently occurring sensory disabilities worldwide. The association between hearing loss and postural instability in an older population remains to be studied. Objective: To determine whether the odds...
Fri Apr 24, 2020 13:22
The Importance of Including Otolaryngologists With Geriatric-Specific Training in Research on Older Patients Undergoing Head and Neck Surgery. JAMA Otolaryngol Head Neck Surg. 2020 Apr 23;: Authors: Parham K PMID: 32324225 [PubMed - as supplied by publisher]
Fri Apr 24, 2020 13:22
Aerosol or droplet: critical definitions in the COVID-19 era. Int Forum Allergy Rhinol. 2020 Apr 23;: Authors: Kohanski MA, Palmer JN, Cohen NA PMID: 32323923 [PubMed - as supplied by publisher]
Fri Apr 24, 2020 13:22
Proton and photon radiosensitization effects of niraparib, a PARP-1/-2 inhibitor, on human head and neck cancer cells. Head Neck. 2020 Apr 23;: Authors: Wang L, Cao J, Wang X, Lin E, Wang Z, Li Y, Li Y, Chen M, Wang X, Jiang B, Zhang R, Sahoo N, Zhang X, Zhu XR, Myers JN, Frank SJ Abstract BACKGROUND: Combining photon or proton radiotherapy with targeted therapy shows promise for head and neck cancer (HNSCC). The poly (adenosine diphosphate [ADP]-ribose)...
Fri Apr 24, 2020 13:22
Clinical significance of circulating tumor cells in patients with locally advanced head and neck squamous cell carcinoma. Oncol Rep. 2020 Mar 09;: Authors: Liu K, Chen N, Wei J, Ma L, Yang S, Zhang X Abstract The present study aimed to investigate the clinical relevance of circulating tumor cells (CTCs) in patients with locally advanced head and neck squamous cell carcinoma (LA‑HNSCC), particularly in patients with nasopharyngeal and hypopharyngeal...
Fri Apr 24, 2020 13:22
Comprehensive circular RNA expression profiling with associated ceRNA network reveals their therapeutic potential in cholesteatoma. Oncol Rep. 2020 Feb 12;: Authors: Gao J, Tang Q, Xue R, Zhu X, Wang S, Zhang Y, Liu W, Gao Z, Yang H Abstract Cholesteatoma is a chronic disease that pathologically displays a benign tumor with excessive squamous epithelial cell proliferation in the middle ear. Clinically, however, it can manifest malignant behavior...
Fri Apr 24, 2020 13:22
The role of cytokines in head and neck squamous cell carcinoma: A review. Clin Ter. 2020 May-Jun;171(3):e268-e274 Authors: Ralli M, Grasso M, Gilardi A, Ceccanti M, Messina MP, Tirassa P, Fiore M, Altissimi G, A Salzano F, De Vincentiis M, Greco A Abstract Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide, accounting for approximately 6% of all cancer cases and responsible for an estimated 1-2% of all cancer...
Fri Apr 24, 2020 13:22
Dental Monitoring Application: it is a valid innovation in the Orthodontics Practice? Clin Ter. 2020 May-Jun;171(3):e260-e267 Authors: Impellizzeri A, Horodinsky M, Barbato E, Polimeni A, Philippe S, Galluccio G Abstract AIM: The aim of research is to show the effectiveness of 0.014X0.025 CuNiTi wires in self-ligating straight-wire appliance in the working time of 10 weeks, the treatments are monitored with the Dental Monitoring® Applications. A...
Fri Apr 24, 2020 13:22
The common marmoset as suitable non-human alternative for the analysis of primate cochlear development. FEBS J. 2020 Apr 23;: Authors: Hosoya M, Fujioka M, Murayama AY, Okano H, Ogawa K Abstract Cochlear development is a complex process with precise spatiotemporal patterns. A detailed understanding of this process is important for studies of congenital hearing loss and regenerative medicine. However, much of our understanding of cochlear development...
Fri Apr 24, 2020 13:22
Programming a Cochlear Implant for Tinnitus Suppression. J Am Acad Audiol. 2020 Apr;31(4):302-308 Authors: Perreau A, Tyler R, Mancini PC Abstract BACKGROUND: Electrical stimulation of the cochlea to treat tinnitus has been explored for decades. However, few studies have investigated the most salient programming parameters for tinnitus suppression in cochlear implant (CI) patients. PURPOSE: The purpose of this study was to review the...
Fri Apr 24, 2020 13:22
MRI-based static and functional assessment of complex hip deformities in comparison with CT: a validation study. MAGMA. 2020 Apr 22;: Authors: Blum S, Franken L, Hartmann A, Thielemann F, Plodeck V, Danowski D, Kühn JP, Hoffmann RT, Günther KP, Goronzy J Abstract OBJECTIVE: This study aimed at investigating the agreement between predefined quantitative parameters of hip morphology derived from magnetic resonance imaging (MRI) and virtual range of...
Fri Apr 24, 2020 13:22
Older age is a risk factor associated with poor prognosis of patients with squamous cell carcinoma of the oral cavity. Eur Arch Otorhinolaryngol. 2020 Apr 22;: Authors: Chen S, Lin Z, Chen J, Yang A, Zhang Q, Xie C, Zhang X, Yang Z, Chen W, Song M Abstract PURPOSE: Whether or not young patients with squamous cell carcinoma of oral cavity (OC-SCC) have a difference in prognosis remains a controversy. This study aimed to analyze the clinical characteristics...
Fri Apr 24, 2020 13:22
Tracheostomy in the COVID-19 pandemic. Eur Arch Otorhinolaryngol. 2020 Apr 22;: Authors: Mattioli F, Fermi M, Ghirelli M, Molteni G, Sgarbi N, Bertellini E, Girardis M, Presutti L, Marudi A Abstract PURPOSE: The role of tracheostomy in COVID-19-related ARDS is unknown. Nowadays, there is no clear indication regarding the timing of tracheostomy in these patients. METHODS: We describe our synergic experience between ENT and ICU Departments...
Fri Apr 24, 2020 13:22
A Novel Rat Model to Test Intra-Abdominal Anti-adhesive Therapy. Front Surg. 2020;7:12 Authors: Vediappan RS, Bennett C, Bassiouni A, Smith M, Finnie J, Trochsler M, Psaltis AJ, Vreugde S, Wormald PJ Abstract Background: Adhesion formation after abdominal surgery is considered almost inevitable and a major cause of morbidity. Novel treatments have been proposed, however there is a lack of suitable small animal models for pre-clinical evaluation,...
Fri Apr 24, 2020 13:22
Human Papilloma Virus Increases ΔNp63α Expression in Head and Neck Squamous Cell Carcinoma. Front Cell Infect Microbiol. 2020;10:143 Authors: Citro S, Bellini A, Medda A, Sabatini ME, Tagliabue M, Chu F, Chiocca S Abstract P63, and in particular the most expressed ΔNp63α isoform, seems to have a critical role in the outcome of head and neck cancer. Many studies have been conducted to assess the possible use of p63 as a prognostic marker in squamous...
Fri Apr 24, 2020 13:22
Microbiotyping the Sinonasal Microbiome. Front Cell Infect Microbiol. 2020;10:137 Authors: Bassiouni A, Paramasivan S, Shiffer A, Dillon MR, Cope EK, Cooksley C, Ramezanpour M, Moraitis S, Ali MJ, Bleier BS, Callejas C, Cornet ME, Douglas RG, Dutra D, Georgalas C, Harvey RJ, Hwang PH, Luong AU, Schlosser RJ, Tantilipikorn P, Tewfik MA, Vreugde S, Wormald PJ, Caporaso JG, Psaltis AJ Abstract This study offers a novel description of the sinonasal microbiome,...
Fri Apr 24, 2020 13:22
Neck emphysema in a HNSCC cancer patient undergoing concurrent radiotherapy and cetuximab. Rep Pract Oncol Radiother. 2020 May-Jun;25(3):396-398 Authors: Nardone V, Calvanese MG, D'Onofrio I, Di Stasio M, Vitale C, Silvestri A, Daniele B, Correale P, Fierro P, Tortoriello G, Reginelli A, Cappabianca S, Guida C Abstract Background: Lung toxicity in patients undergoing cetuximab and radiotherapy (Cetux-RT) for head and neck squamous cell carcinoma...
Fri Apr 24, 2020 13:22
A comparative study between open-face and closed-face masks for head and neck cancer (HNC) in radiation therapy. Rep Pract Oncol Radiother. 2020 May-Jun;25(3):382-388 Authors: Mulla Z, Alwassia RK, Senan EM, Soaida S, Mohamed AAMA, Almerdhemah H, Iqbal HA, Muamenah HM Abstract Aim: To determine the setup reproducibility in the radiation treatment of Head and Neck (HN) patients using open face head and shoulder masks (OHSM) with customized headrest...
Fri Apr 24, 2020 13:22
The Supernatant of Tonsil-Derived Mesenchymal Stem Cell Has Antiallergic Effects in Allergic Rhinitis Mouse Model. Mediators Inflamm. 2020;2020:6982438 Authors: Park IS, Kim JH, Bae JS, Kim DK, Mo JH Abstract Methods: We isolated T-MSCs from human palatine tonsil and evaluated the ingredients of T-MSCs-CM. The effect of T-MSCs-CM was evaluated in the AR mouse model that was randomly divided into five groups (negative control, positive control, and...
Fri Apr 24, 2020 13:22
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