Microorganisms, Vol. 8, Pages 648: Microbial Screening Based on the Mizoroki–Heck Reaction Permits Exploration of Hydroxyhexylitaconic-Acid-Producing Fungi in Soils Microorganisms doi: 10.3390/microorganisms8050648 Authors: Sano Yada Nomura Kusukawa Ando Matsumoto Wada Tanaka Ohara Aso Recently, we developed a unique microbial screening method based on the Mizoroki–Heck reaction for itaconic acid (IA)-producing fungi. This method revealed...
Wed Apr 29, 2020 03:00
Microorganisms, Vol. 8, Pages 650: Recombinant Filamentous Bacteriophages Encapsulated in Biodegradable Polymeric Microparticles for Stimulation of Innate and Adaptive Immune Responses Microorganisms doi: 10.3390/microorganisms8050650 Authors: Jamaledin Sartorius Di Natale Vecchione De Berardinis Netti Escherichia coli filamentous bacteriophages (M13, f1, or fd) have attracted tremendous attention from vaccinologists as a promising immunogenic carrier and vaccine...
Wed Apr 29, 2020 03:00
Microorganisms, Vol. 8, Pages 651: Current State of Anthrax Vaccines and Key R&D Gaps Moving Forward
Microorganisms, Vol. 8, Pages 651: Current State of Anthrax Vaccines and Key R&D Gaps Moving Forward Microorganisms doi: 10.3390/microorganisms8050651 Authors: Clark Wolfe A licensed anthrax vaccine has been available for pre-exposure prophylaxis in the United States since 1970, and it was approved for use as a post-exposure prophylaxis, in combination with antibiotic treatment, in 2015. A variety of other vaccines are available in other nations, approved under various regulatory...
Wed Apr 29, 2020 03:00
Microorganisms, Vol. 8, Pages 649: Molecular Identification of Borrelia afzelii from Ticks Parasitizing Domestic and Wild Animals in South Korea Microorganisms doi: 10.3390/microorganisms8050649 Authors: Seo Kwon Kwak Lyme borreliosis is one of the most prevalent tick-borne infectious zoonotic diseases caused by spirochetes of the Borrelia burgdorferi sensu lato group. The present study assessed the risk factors and prevalence of Lyme borreliosis in ticks parasitizing domestic...
Wed Apr 29, 2020 03:00
Microorganisms, Vol. 8, Pages 647: Biocontrol of Rice Seedling Rot Disease Caused by Curvularia lunata and Helminthosporium oryzae by Epiphytic Yeasts from Plant Leaves Microorganisms doi: 10.3390/microorganisms8050647 Authors: Savitree Limtong Parichat Into Panchapond Attarat Seedling rot disease in rice leads to significant loss in the production of seedlings. This research was conducted to explore yeasts that could be used as biological control agents against rice seedling rot...
Wed Apr 29, 2020 03:00
Microorganisms, Vol. 8, Pages 646: Lipocalin2 Induced by Bacterial Flagellin Protects Mice against Cyclophosphamide Mediated Neutropenic Sepsis Microorganisms doi: 10.3390/microorganisms8050646 Authors: Daejin Lim Hee Kyung Kim Jae-Ho Jeong Yoon Seok Jung Shee Eun Lee Hee-Chang Jang Sook-In Jung Hueng-Sik Choi Joon Haeng Rhee Sung-Gwon Lee Chungoo Park Miryoung Song Hyon E. Choy Neutropenic sepsis is a fatal consequence of chemotherapy, and septic...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2091: Ulva intestinalis Protein Extracts Promote In Vitro Collagen and Hyaluronic Acid Production by Human Dermal Fibroblasts Molecules doi: 10.3390/molecules25092091 Authors: Justine Bodin Amandine Adrien Pierre-Edouard Bodet Delphine Dufour Stanislas Baudouin Thierry Maugard Nicolas Bridiau With the increase in life expectancy, reducing the visible signs of skin aging has become a major issue. A reduction in collagen and hyaluronic acid synthesis...
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Molecules, Vol. 25, Pages 2090: Polydopamine Nanosphere with In-Situ Loaded Gentamicin and Its Antimicrobial Activity Molecules doi: 10.3390/molecules25092090 Authors: Rahila Batul Mrinal Bhave Peter J. Mahon Aimin Yu The mussel inspired polydopamine has acquired great relevance in the field of nanomedicines, owing to its incredible physicochemical properties. Polydopamine nanoparticles (PDA NPs) due to their low cytotoxicity, high biocompatibility and ready biodegradation have...
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Molecules, Vol. 25, Pages 2089: Recent Advances in Luminescence Imaging of Biological Systems Using Lanthanide(III) Luminescent Complexes Molecules doi: 10.3390/molecules25092089 Authors: Monteiro The use of luminescence in biological systems allows one to diagnose diseases and understand cellular processes. Molecular systems, particularly lanthanide(III) complexes, have emerged as an attractive system for application in cellular luminescence imaging due to their long emission lifetimes,...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2084: Tricin Isolated from Enzyme-Treated Zizania latifolia Extract Inhibits IgE-Mediated Allergic Reactions in RBL-2H3 Cells by Targeting the Lyn/Syk Pathway Molecules doi: 10.3390/molecules25092084 Authors: Lee Park Jhee Yang Tricin, a flavone present in rice bran, is confirmed as the major efficacious compound present in the enzyme-treated Zizania latifolia extract (ETZL), which protects against UVB-induced skin-aging. However, the suppressive...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2087: Mechanistic Understanding of Peptide Analogues, DALDA, [Dmt1]DALDA, and KGOP01, Binding to the mu Opioid Receptor Molecules doi: 10.3390/molecules25092087 Authors: Maria Dumitrascuta Marcel Bermudez Steven Ballet Gerhard Wolber Mariana Spetea The mu opioid receptor (MOR) is the primary target for analgesia of endogenous opioid peptides, alkaloids, synthetic small molecules with diverse scaffolds, and peptidomimetics. Peptide-based opioids are...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2086: Development of Chitosan/Mannitol Microparticles as Delivery System for the Oral Administration of a Spirulina Bioactive Peptide Extract Molecules doi: 10.3390/molecules25092086 Authors: Aquino Auriemma Conte Esposito Sommella Campiglia Sansone Spirulina platensis contains several compounds showing nutritional and therapeutic benefits. Recently, a series of peptides able to reduce the blood pressure level and to enhance the endothelial...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2088: Lactobacillus-Derived Bioactive Metabolites for the Regulation of Periodontal Health: Evidences to Clinical Setting Molecules doi: 10.3390/molecules25092088 Authors: Benso Sulijaya Naoki Takahashi Kazuhisa Yamazaki Background: Gut microbiota plays a pivotal role in regulating host metabolism that affects the systemic health. To date, several studies have confirmed the fact that microbiota interacts with host, modulating immunity, controlling the...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2083: Diverse Terpenoids and Their Associated Antifungal Properties from Roots of Different Cultivars of Chrysanthemum morifolium Ramat Molecules doi: 10.3390/molecules25092083 Authors: Kaige Zhang Yifan Jiang Hongwei Zhao Tobias G. Köllner Sumei Chen Fadi Chen Feng Chen Roots provide anchorage and enable the absorption of water and micronutrients from the soil for plants. Besides these essential functions, roots are increasingly being recognized...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2082: Leek or Garlic? A Chemical Evaluation of Elephant Garlic Volatiles Molecules doi: 10.3390/molecules25092082 Authors: Roberta Ascrizzi Guido Flamini “Aglione della Valdichiana” is listed among the Traditional Agronomic and Edible Products of Italy, as it is a typical product of the Chiana Valley (Tuscany, Italy). It is also known as “elephant garlic”, due to the dimension of its cloves, and, other than in the Italian...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2081: Mangiferin Rich Products from Aphloia theiformis (Vahl) Benn Leaves: Extraction, Fractionation, Phytochemical Characterization, and Antioxidant Properties Molecules doi: 10.3390/molecules25092081 Authors: Grauzdytė Pukalskas Kalamouni Venskutonis Aphloia theiformis is traditionally used in Mauritius, Madagascar, and Reunion Island for treating several diseases. In this study, various extraction solvents and schemes were applied for the recovery...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2085: Computational NMR Spectroscopy of Ionic Liquids: [C4C1im]Cl/Water Mixtures Molecules doi: 10.3390/molecules25092085 Authors: Giacomo Saielli In this work, I have analyzed the structure of binary mixtures of 1-butyl-3-methylimidazolium chloride ionic liquid, [C4C1im]Cl, and water, using computational NMR spectroscopy. The structure of the complex fluid phase, where the ionic and hydrophobic nature of ionic liquids is further complicated by the addition...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2080: Porphyrin Derivative Nanoformulations for Therapy and Antiparasitic Agents Molecules doi: 10.3390/molecules25092080 Authors: Daiana K. Deda Bernardo A. Iglesias Eduardo Alves Koiti Araki Celia R. S. Garcia Porphyrins and analogous macrocycles exhibit interesting photochemical, catalytic, and luminescence properties demonstrating high potential in the treatment of several diseases. Among them can be highlighted the possibility of application...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2079: Fourier Transform Infrared Spectroscopy Based Complimentary Diagnosis Tool for Autism Spectrum Disorder in Children and Adolescents Molecules doi: 10.3390/molecules25092079 Authors: Gulce Ogruc Ildiz Sevgi Bayari Ahmet Karadag Ersin Kaygisiz Rui Fausto Autism spectrum disorder (ASD) is a neurodevelopmental disorder that begins early in life and continues lifelong with strong personal and societal implications. It affects about 1%–2% of the...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2077: New 8-C-p-Hydroxylbenzylflavonol Glycosides from Pumpkin (Cucurbita moschata Duch.) Tendril and Their Osteoclast Differentiation Inhibitory Activities Molecules doi: 10.3390/molecules25092077 Authors: Kiok Kim Joo-Hee Choi Jisu Oh Ji-Yeon Park Young-Min Kim Jae-Hak Moon Jong-Hwan Park Jeong-Yong Cho Six new 8-C-p-hydroxybenzylflavonol glycosides were isolated from a hot water extract of pumpkin (Cucurbita moschata Duch.) tendril and...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2078: Practical Synthesis of Quinoline-Protected Morpholino Oligomers for Light-Triggered Regulation of Gene Function Molecules doi: 10.3390/molecules25092078 Authors: Davide Deodato Timothy M. Dore Photoactivatable cyclic caged morpholino oligomers (ccMOs) represent a promising tool to selectively regulate gene expression with spatiotemporal control. Nevertheless, some challenges associated with the preparation of these reagents have limited their broader...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2072: Stability Evaluation of DMT and Harmala Alkaloids in Ayahuasca Tea Samples Molecules doi: 10.3390/molecules25092072 Authors: Gabriela de Oliveira Silveira Rafael Guimarães dos Santos Felipe Rebello Lourenço Giordano Novak Rossi Jaime Hallak Mauricio Yonamine Ayahuasca tea is a hallucinogenic beverage used for religious purposes in Brazil and many other countries that has therapeutic potential in the treatment of some mental health disorders....
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2075: Phenolic Compounds of Soybean Seeds from Two European Countries and Their Antioxidant Properties Molecules doi: 10.3390/molecules25092075 Authors: Angelika Król-Grzymała Ryszard Amarowicz There is only a small acreage of planted soybeans in northern Europe, as the global production of this crop is mainly dictated by the warmer temperatures needed for bountiful yields. The defense response of soybean plants to a cold climate entails the secretion of...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2074: The Influence of Plant Material Enzymatic Hydrolysis and Extraction Conditions on the Polyphenolic Profiles and Antioxidant Activity of Extracts: A Green and Efficient Approach Molecules doi: 10.3390/molecules25092074 Authors: Aneta Krakowska-Sieprawska Katarzyna Rafińska Justyna Walczak-Skierska Bogusław Buszewski The aim of this study was to develop a new comprehensive extraction protocol based on green technology for the enhanced release of...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2073: A Hybrid Nanomaterial Based on Single Walled Carbon Nanotubes Cross-Linked via Axially Substituted Silicon (IV) Phthalocyanine for Chemiresistive Sensors Molecules doi: 10.3390/molecules25092073 Authors: Maxim Polyakov Victoria Ivanova Darya Klyamer Baybars Köksoy Ahmet Şenocak Erhan Demirbaş Mahmut Durmuş Tamara Basova In this work, the novel hybrid nanomaterial SWCNT/SiPc made of single walled carbon nanotubes (SWCNT) cross-linked...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2076: Pharmacological (or Synthetic) and Nutritional Agonists of PPAR-γ as Candidates for Cytokine Storm Modulation in COVID-19 Disease Molecules doi: 10.3390/molecules25092076 Authors: Carmen Ciavarella Ilenia Motta Sabrina Valente Gianandrea Pasquinelli The cytokine storm is an abnormal production of inflammatory cytokines, due to the over-activation of the innate immune response. This mechanism has been recognized as a critical mediator of influenza-induced...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2070: Structure-Activity-Relationship and Mechanistic Insights for Anti-HIV Natural Products Molecules doi: 10.3390/molecules25092070 Authors: Ramandeep Kaur Pooja Sharma Girish K. Gupta Fidele Ntie-Kang Dinesh Kumar Acquired Immunodeficiency Syndrome (AIDS), which chiefly originatesfroma retrovirus named Human Immunodeficiency Virus (HIV), has impacted about 70 million people worldwide. Even though several advances have been made in the field of...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2071: Study of Caspase 8 Inhibition for the Management of Alzheimer’s Disease: A Molecular Docking and Dynamics Simulation Molecules doi: 10.3390/molecules25092071 Authors: Syed Sayeed Ahmad Meetali Sinha Khurshid Ahmad Mohammad Khalid Inho Choi Alzheimer's disease (AD) is the most common type of dementia and usually manifests as diminished episodic memory and cognitive functions. Caspases are crucial mediators of neuronal death in a number of neurodegenerative...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2068: Inhibition of Programmed Death Receptor-1/Programmed Death Ligand-1 Interactions by Ginsenoside Metabolites Molecules doi: 10.3390/molecules25092068 Authors: Nam-Hui Yim Young Soo Kim Hwan-Suck Chung Evidence suggests that programmed death receptor-1/programmed death ligand-1 (PD-1/PD-L1) targeted inhibitors act as an immune checkpoint blockade, indicating that these compounds may be useful in cancer immunotherapy by inhibiting the immune response...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2069: Mustard Seed (Brassica nigra) Extract Exhibits Antiproliferative Effect against Human Lung Cancer Cells through Differential Regulation of Apoptosis, Cell Cycle, Migration, and Invasion Molecules doi: 10.3390/molecules25092069 Authors: Asmaa Gamal Ahmed Usama Khamis Hussein Amr E. Ahmed Kyoung Min Kim Hamada M. Mahmoud Ola Hammouda Kyu Yun Jang Anupam Bishayee Lung cancer is the primary cause of cancer-related death worldwide, and...
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2067: Antioxidant Effects, Antiproliferative Effects, and Molecular Docking of Clinacanthus nutans Leaf Extracts Molecules doi: 10.3390/molecules25092067 Authors: Noor Zafirah Ismail Zaleha Md Toha Musthahimah Muhamad Nik Nur Syazni Nik Mohamed Kamal Nur Nadhirah Mohamad Zain Hasni Arsad Clinacanthus nutans is a well-known herb that has been used as an alternative and therapeutic medicine, however more selective C. nutans extracts are needed....
Wed Apr 29, 2020 03:00
Molecules, Vol. 25, Pages 2066: Flavonoids Distinctly Stabilize Lymph Endothelial- or Blood Endothelial Disintegration Induced by Colon Cancer Spheroids SW620 Molecules doi: 10.3390/molecules25092066 Authors: Julia Berenda Claudia Smöch Christa Stadlbauer Eva Mittermair Karin Taxauer Nicole Huttary Georg Krupitza Liselotte Krenn The health effects of plant phenolics in vegetables and other food and the increasing evidence of the preventive potential of flavonoids...
Wed Apr 29, 2020 03:00
MTI, Vol. 4, Pages 15: Generation of Head Movements of a Robot Using Multimodal Features of Peer Participants in Group Discussion Conversation Multimodal Technologies and Interaction doi: 10.3390/mti4020015 Authors: Hung-Hsuan Huang Seiya Kimura Kazuhiro Kuwabara Toyoaki Nishida In recent years, companies have been seeking communication skills from their employees. Increasingly more companies have adopted group discussions during their recruitment process to evaluate the applicants’...
Wed Apr 29, 2020 03:00
Nanomaterials, Vol. 10, Pages 841: Mechanical Characterization on Solvent Treated Cellulose Nanofiber Preforms Using Solution Dipping–Hot Press Technique Nanomaterials doi: 10.3390/nano10050841 Authors: Devendran Thirunavukarasu Yoshinobu Shimamura Keiichiro Tohgo Tomoyuki Fujii Nanocomposites films were prepared by impregnating the solvent treated cellulose nanofiber (SCNF) preforms with epoxy resin using a solution dipping–hot press technique. We investigated the...
Wed Apr 29, 2020 03:00
Nanomaterials, Vol. 10, Pages 860: The Terahertz Dynamics of an Aqueous Nanoparticle Suspension: An Inelastic X-ray Scattering Study Nanomaterials doi: 10.3390/nano10050860 Authors: Alessio De Francesco Luisa Scaccia Ferdinando Formisano Eleonora Guarini Ubaldo Bafile Marco Maccarini Ahmet Alatas Yong Q. Cai Alessandro Cunsolo We used the high-resolution Inelastic X-ray Scattering beamline of the Advanced Photon Source at Argonne National Laboratory to measure...
Wed Apr 29, 2020 03:00
Nanomaterials, Vol. 10, Pages 861: Ag2S QDs/Si Heterostructure-Based Ultrasensitive SWIR Range Detector Nanomaterials doi: 10.3390/nano10050861 Authors: Tretyakov Svyatodukh Perepelitsa Ryabchun Kaurova Shurakov Smirnov Ovchinnikov Goltsman In the 20th century, microelectronics was revolutionized by silicon—its semiconducting properties finally made it possible to reduce the size of electronic components to a few nanometers. The ability to...
Wed Apr 29, 2020 03:00
Nanomaterials, Vol. 10, Pages 857: Photoluminescence of ZnO Nanowires: A review Nanomaterials doi: 10.3390/nano10050857 Authors: Galdámez-Martinez Santana Güell Martínez-Alanis Dutt One-dimensional ZnO nanostructures (nanowires/nanorods) are attractive materials for applications such as gas sensors, biosensors, solar cells, and photocatalysts. This is due to the relatively easy production process of these kinds of nanostructures with excellent charge carrier transport...
Wed Apr 29, 2020 03:00
Nanomaterials, Vol. 10, Pages 858: Polyvinyl Alcohol-Few Layer Graphene Composite Films Prepared from Aqueous Colloids. Investigations of Mechanical, Conductive and Gas Barrier Properties Nanomaterials doi: 10.3390/nano10050858 Authors: Van der Schueren Marouazi Mohanty Lévêque Sutter Romero Janowska Quasi all water soluble composites use graphene oxide (GO) or reduced graphene oxide (rGO) as graphene based additives despite the long and harsh conditions required...
Wed Apr 29, 2020 03:00
Nanomaterials, Vol. 10, Pages 859: Polyelectrolyte Multilayer Films Modification with Ag and rGO Influences Platelets Activation and Aggregate Formation under In Vitro Blood Flow Nanomaterials doi: 10.3390/nano10050859 Authors: Imbir Mzyk Trembecka-Wójciga Jasek-Gajda Plutecka Schirhagl Major Surface functionalization of materials to improve their hemocompatibility is a challenging problem in the field of blood-contacting devices and implants. Polyelectrolyte...
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