Sat Apr 25, 2020 03:00
Abstract Purpose The aim of the present study was to evaluate the rheumatic profile in acromegalic patients to better characterize joint pain. Methods The immunological pattern (rheumatoid factor; antinuclear antibodies—ANA, extractable nuclear antigens—ENA-Ab; anti-citrullinated protein antibodies; erythrocyte sedimentation rate) was evaluated in...
Fri Apr 24, 2020 03:00
This protocol describes the method, materials, equipment and steps for bottom-up preparation of RNA and protein producing synthetic cells. The inner aqueous compartment of the synthetic cells contained the S30 bacterial lysate encapsulated within a lipid bilayer (i.e., stable liposomes), using a water-in-oil emulsion transfer method.
Mon Apr 27, 2020 20:03
This article describes a fast and simple manufacturing process of ionic electromechanically active composite materials for actuators in biomedical, biomimetic and soft robotics applications. The key fabrication steps, their importance for the actuators' final properties, and some of the main characterization techniques are described in detail.
Sat Apr 25, 2020 20:37
Here, we present a protocol to detach corneal endothelial cells (CEC) from Descemet’s membrane (DM) using a neodymium:YAG (Nd:YAG) laser as an ex vivo disease model for bullous keratopathy (BK).
Fri Apr 24, 2020 22:00
This method estimates the absorbed dose of different structures for peptide-receptor-radionuclide-therapy (PRRT) with the possibility of avoiding organ overlap on 2D-projections. Serial whole-body planar images permit estimation of mean absorbed doses along the whole body, while the hybrid approach, combining planar images and 3D-SPECT/CT image, overcomes the limitations of structure overlapping.
Fri Apr 24, 2020 21:27
Here, we present an automated plasma protein digestion method for mass spectrometry-based quantitative proteomic analysis. In this protocol, the liquid transferring and incubation steps for protein denaturation, reduction, alkylation, and trypsin digestion reactions are streamlined and automated. It takes approximately five hours to prepare a 96-well plate with desired precision.
Fri Apr 24, 2020 21:00
Objectives: The objective of this study was to develop and evaluate abbreviated versions of the Word Auditory Recognition and Recall Measure (WARRM) as part of an iterative process in the development of a feasible test for potential future clinical use. Design: The three original WARRM (O-WARRM) randomizations were modified by altering the presentation paradigm. Instead of presenting 5 trials per set size with set size increasing from 2 to 6 as in the O-WARRM (n = 100 words), the experimental...
Thu Apr 23, 2020 03:00
Objectives: According to the International Classification of Functioning, Disability and Health (ICF), functioning reflects the interplay between an individual’s body structures and functions, activities, participation, environmental, and personal factors. To be useful in clinical practice, these concepts need to be operationalized into a practical and integral instrument. The Brief ICF Core Set for Hearing Loss (CSHL) provides a minimum standard for the assessment of functioning in adults with...
Thu Apr 23, 2020 03:00
Objectives: In adult cochlear implant patients, conventional audiometry is used to measure postoperative residual hearing which requires active listening and patient feedback. However, audiological measurements in pediatric cochlear implant patients are both challenging as well as time consuming. Intracochlear electrocochleography (ECOG) offers an objective and a time-efficient method to measure frequency-specific cochlear microphonic or difference thresholds (CM/DIF) thresholds that closely approximate...
Thu Apr 23, 2020 03:00
Abstract Purpose The aim of this study was to evaluate the hard and soft tissue effects and differences of the Alt-RAMEC protocol to the facemask and conventional facemask protocols in patients with unilateral cleft lip and palate. Methods This prospective study was carried out with 30 patients with unilateral cleft lip and palate with...
Mon Apr 27, 2020 19:51
Zusammenfassung Die deutschen Universitätspathologien sind durch die Corona-Pandemie und die entsprechenden Maßnahmen in allen Bereichen betroffen. Hierzu wurde eine Umfrage unter den 36 Deutschen Universitätspathologien durchgeführt (Rücklauf 83 %) und ausgewertet. Die Ergebnisse sind zusammengestellt und erlauben eine Bewertung der aktuellen Situation; sie zeigen erhebliche Einschränkungen vor allem im wissenschaftlichen und diagnostischen Bereich und eine hohe Bereitschaft...
Mon Apr 27, 2020 03:00
Abstract Purpose To investigate the impact of menstrual cycle on patients undergoing gynecological endoscopic surgery. Patients and methods 220 patients scheduled for gynecological endoscopic surgery under general anesthesia were selected. The patients were divided into three groups based on 3 phases of menstrual cycle which are the follicular phase...
Mon Apr 27, 2020 03:00
BACKGROUND The incidence of reactions to epinephrine-containing local anesthetics in Mohs micrographic surgery (MMS) has not been established. OBJECTIVE To estimate the incidence of epinephrine-induced reactions from local anesthetics in patients who undergo MMS for the removal of cutaneous malignancies. METHODS From 2016 to 2018, 200 MMS patients were recruited from the authors' surgical center. Assessments were obtained throughout the entirety of the Mohs cases during a single visit. ...
Mon Apr 27, 2020 19:31
BACKGROUND The patient consent process traditionally relies on conversations between the physician and the patient and rarely utilizes supplemental multimedia aids. OBJECTIVE To determine whether the addition of an educational video on Mohs micrographic surgery (MMS) can improve patient satisfaction with the consent process. MATERIALS AND METHODS This prospective observational quality improvement study compared the outcomes of traditional patient consent alone versus standard consent...
Mon Apr 27, 2020 19:31
No abstract available
Mon Apr 27, 2020 19:31
BACKGROUND Multimedia educational materials have been found to improve aspects of informed consent, although data in the context of Mohs micrographic surgery (MMS) is limited. OBJECTIVE To assess whether a preoperative educational video decreases anxiety, increases comprehension, and improves overall satisfaction for patients undergoing same-day office consultation and MMS. MATERIALS AND METHODS This single-center randomized controlled trial included patients above the age of 18 years...
Mon Apr 27, 2020 19:31
No abstract available
Mon Apr 27, 2020 19:31
BACKGROUND Insurance companies have implemented new policies including excessive prior authorization (PA) requirements, high-deductible plans, and complicated billing structures in an effort to curb rising health care costs. Studies investigating the real-time impact on providers and patients are emerging, but few within the field of dermatology have been published. OBJECTIVE To assess the impact of cost-cutting policies on patients and physicians. METHODS A survey was electronically...
Mon Apr 27, 2020 19:31
No abstract available
Mon Apr 27, 2020 19:31
BACKGROUND Light-emitting diode (LED) has been used for wound healing because of its stimulatory effects on fibroblast proliferation, matrix synthesis, angiogenesis, and downmodulation of inflammatory reactions. OBJECTIVE The aim of the authors' study was to investigate the effects of red LED (wavelength 633 nm) photomodulation on lower extremity surgical defects left to heal by secondary intention. MATERIALS AND METHODS Fourteen subjects with surgical defects of the lower leg were irradiated...
Mon Apr 27, 2020 19:31
BACKGROUND Hidradenitis suppurativa (HS) is a chronic, inflammatory condition characterized by recurrent nodules, sinus tracts, comedones, and scarring. Hidradenitis suppurativa is often associated with pain and decreased quality of life. Limited clinical trial data exist regarding the management of acute HS lesions, but clinical experience and a prospective case series suggest that intralesional triamcinolone may be useful. OBJECTIVE To compare the efficacy of intralesional triamcinolone...
Mon Apr 27, 2020 19:31
BACKGROUND Mohs micrographic surgery, excisional surgery, and electrodessication and curettage (ED&C) are common dermatologic procedures that often use electrodessication through hyfrecators to achieve hemostasis. According to in vitro studies, electrodessication is considered safe in patients with implanted cardiac devices. To the authors' knowledge, there are no in vivo data to support this claim. OBJECTIVE In this study, the authors aim to describe the outcomes of hyfrecation during...
Mon Apr 27, 2020 19:31
No abstract available
Mon Apr 27, 2020 19:31
No abstract available
Mon Apr 27, 2020 19:31
No abstract available
Mon Apr 27, 2020 19:31
BACKGROUND Historically, garlic containing compounds have been used on wounds to improve healing and ward off infection. Researchers have tested many of these ancient ointments, discovering that garlic is a common ingredient in those that are effective. OBJECTIVE To determine the efficacy of topical garlic on surgical wounds compared with Vaseline by analysis of visual analog scales and digital photograph analysis. MATERIALS AND METHODS Seventeen patients with 2 skin excisions applied...
Mon Apr 27, 2020 19:31
No abstract available
Mon Apr 27, 2020 19:31
BACKGROUND Although the use of 2-octylcyanoacrylate (OCA) in cutaneous surgery offers increased efficiency, there is scant data comparing scar outcomes achieved with OCA versus 5-0 fast-absorbing gut suture (FG). OBJECTIVE To compare scar cosmesis achieved with OCA versus FG for surgical wound closure. MATERIALS AND METHODS A total of 44 patients with postoperative defects of at least 3 cm were included. Half of each wound was randomized to receive closure with either OCA or FG. At 3...
Mon Apr 27, 2020 19:31
BACKGROUND Vascular compromise and subsequent tissue necrosis is a rare but disfiguring complication of dermal filler injection that frequently occurs in regions of the lip and nasolabial fold supplied by the superior labial artery (SLA). OBJECTIVE The purpose of this study was to examine lumen diameter and other anatomical features of the SLA relevant to dermal filler injection in the clinical setting. MATERIALS AND METHODS Eighteen adult cadavers were dissected. Detailed measurements...
Mon Apr 27, 2020 19:31
BACKGROUND The opioid epidemic is a national emergency, and it is imperative that all physicians are engaged in reducing exposure. Among dermatologists, dermatologic surgeons prescribe most opioids with the highest rates of prescription occurring in Southern states. OBJECTIVE Implement a quality improvement intervention to decrease opioids prescribed and filled to
Mon Apr 27, 2020 19:31
BACKGROUND Orthonyxia is an effective, noninvasive treatment for transverse nail curvature deformity. OBJECTIVE To discover the factors influencing treatment results of superelastic wire orthonyxia (SEWO). MATERIAL AND METHODS A retrospective study was conducted using clinical records of patients treated with SEWO. A multiple linear regression model was used to explain the correlation between correction pace (% per week) and the other collected variables (patient age, sex, position of...
Mon Apr 27, 2020 19:31
BACKGROUND Submental fat (SMF) can negatively affect perceptions of health and attractiveness. The Condition of Submental Fullness and Treatment Outcomes Registry (CONTOUR) was designed to understand SMF treatment in clinical practice. OBJECTIVE To report efficacy, treatment characteristics, and safety associated with real-world use of ATX-101 (deoxycholic acid injection). METHODS CONTOUR enrolled adults considering treatment for SMF reduction. ATX-101–treated patients who completed...
Mon Apr 27, 2020 19:31
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