Related ArticlesSIRT3 deficiency is resistant to autophagy-dependent ferroptosis by inhibiting the AMPK/mTOR pathway and promoting GPX4 levels. J Cell Physiol. 2020 Apr 24;: Authors: Han D, Jiang L, Gu X, Huang S, Pang J, Wu Y, Yin J, Wang J Abstract Ferroptosis, an autophagy-dependent cell death, is characterized by lipid peroxidation and iron accumulation, closely associated with pathogenesis of gestational diabetes mellitus (GDM). Sirtuin 3 (SIRT3)...
Related ArticlesTherapeutic effects of extracellular vesicles from human adipose-derived mesenchymal stem cells on chronic experimental autoimmune encephalomyelitis. J Cell Physiol. 2020 Apr 24;: Authors: Jafarinia M, Alsahebfosoul F, Salehi H, Eskandari N, Azimzadeh M, Mahmoodi M, Asgary S, Ganjalikhani Hakemi M Abstract Since in cell therapy, there are always concerns about immune rejection, genetic disability, and malignancies, special attention has...
Related ArticlesAno6 disruption impairs acinar cell regulatory volume decrease and protein secretion in murine submandibular salivary glands. J Cell Physiol. 2020 Apr 24;: Authors: Munemasa T, Gao X, Melvin JE, Mukaibo T Abstract The widely expressed Anoctamin 6 (Ano6) supports different Ca2+ -dependent functions, but little is known about its role in salivary glands. Mouse submandibular gland (SMG) acinar cells exhibited a robust regulatory volume decrease...
Related ArticlesGhrelin promotes midbrain neural stem cells differentiation to dopaminergic neurons through Wnt/β-catenin pathway. J Cell Physiol. 2020 Apr 24;: Authors: Gong B, Jiao L, Du X, Li Y, Bi M, Jiao Q, Jiang H Abstract Ghrelin plays a neuroprotective role in the process of dopaminergic (DAergic) neurons degeneration in Parkinson's disease (PD). However, it still largely unknown whether ghrelin could affect the midbrain neural stem cells (mbNSCs)...
Related Articlesl-Serine transport in growing and maturing mouse oocytes. J Cell Physiol. 2020 Apr 24;: Authors: Zhang H, McClatchie T, Baltz JM Abstract Serine has roles in cell metabolism besides protein synthesis including providing one-carbon units to the folate cycle. Since growing mouse oocytes undergo a burst of folate accumulation as they near full size, we have investigated whether oocytes transport serine. Substantial serine transport appeared...
Related ArticlesAssociation of C-reactive protein (CRP) rs1205 and rs2808630 variants and risk of cancer. J Cell Physiol. 2020 Apr 24;: Authors: Pan HY, Mi YY, Xu K, Zhang Z, Wu H, Zhang W, Yuan W, Shi L, Zhang LF, Zhu LJ, Zuo L Abstract The correlation between rs1205, rs2808630 variants of C-reactive protein (CRP) gene and susceptibility of cancer has been assessed previously, but with conflicting results. We adopted odds ratios (ORs) with 95% confidence...
Related ArticlesNuclear factor of activated T cells 1 and 2 are required for vertebral homeostasis. J Cell Physiol. 2020 Apr 24;: Authors: Canalis E, Schilling L, Eller T, Yu J Abstract The present study defines the function of nuclear factor of activated T cells (NFAT)c1 and NFATc2 in osteoblast function in vivo and in vitro. Nfatc1loxP/loxP , Nfatc2loxP/loxP , and Nfatc1loxP/loxP ;Nfatc2loxP/loxP conditional mice were mated with BGLAP-Cre transgenics...
Related ArticlesThe impact of acute stress disorder on gallbladder interstitial cells of Cajal. J Cell Physiol. 2020 Apr 24;: Authors: Huang ZP, Qiu H, Wang K, Chao WB, Zhu HB, Chen H, Liu Y, Yu BP Abstract Physical and psychological stress exerts a substantial effect on gastrointestinal motility disorders, where trauma enhances symptoms of digestive dysfunction. Interstitial cells of Cajal (ICCs) act as pacemakers for gastrointestinal motility regulation...
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Related ArticlesWhite-matter changes in early and late stages of mild cognitive impairment. J Clin Neurosci. 2020 Apr 22;: Authors: Femir-Gurtuna B, Kurt E, Ulasoglu-Yildiz C, Bayram A, Yildirim E, Soncu-Buyukiscan E, Bilgic B Abstract Mild Cognitive Impairment (MCI) is characterized by cognitive deficits that exceed age-related decline, but not interfering with daily living activities. Amnestic type of the disorder (aMCI) is known to have a high risk...
Related ArticlesDecompressive craniectomy in elderly patients with traumatic brain injury. J Clin Neurosci. 2020 Apr 22;: Authors: Paldor I, Peso D, Sviri GE PMID: 32334961 [PubMed - as supplied by publisher]
Related ArticlesDisability and quality of life in Guillain-Barré syndrome - Longitudinal study. J Clin Neurosci. 2020 Apr 22;: Authors: Berisavac I, Arsenijevic M, Bozovic I, Mladenovic B, Kacar A, Stojiljkovic Tamas O, Petrovic M, Stojanovic M, Vujovic B, Martic V, Jovanovic D, Lavrnic D, Basta I, Peric S Abstract Longitudinal health-related quality of life (QoL) data in Guillain-Barré (GBS) patients are still scarce. We, therefore, investigated health-...
Related ArticlesA transcranial magnetic stimulation study for the investigation of corticospinal motor pathways in children with cerebral palsy. J Clin Neurosci. 2020 Apr 22;: Authors: Tekgul H, Saz U, Yilmaz S, Polat M, Aktan G, Kose T, Kitis O, Gokben S Abstract The aim of this study is to perform transcranial magnetic stimulation (TMS)-based investigation of corticospinal motor pathways in children with cerebral palsy (CP) secondary to hypoxic-ischemic...
Related ArticlesLocally invasive giant spinal paraganglioma. J Clin Neurosci. 2020 Apr 22;: Authors: Yi Chen B, Jose Mizrahi C, Yang Y, Kavar B Abstract Cauda equina paragangliomas are neuroendocrine tumours rarely encountered in neurosurgical practice. Large cauda equina paragangliomas with an intradural and extradural component, dense adhesion to nerve roots and high vascularity are surgically challenging and mandate meticulous operative dissection....
Related ArticlesSmoking-cessation pharmacotherapy for patients with stroke and TIA: Systematic review. J Clin Neurosci. 2020 Apr 22;: Authors: Parikh NS, Salehi Omran S, Kamel H, Elkind MSV, Willey JZ Abstract Data regarding the efficacy and safety of smoking-cessation pharmacotherapy after stroke are lacking. We systematically reviewed data on this topic by searching Medline, Cochrane, and Clinicaltrials.gov to identify randomized clinical trials (RCT)...
Related ArticlesQuality of life in patients with multiple sclerosis and caregivers. Predictive factors: An observational study. J Clin Neurosci. 2020 Apr 22;: Authors: Di Cara M, Bonanno L, Rifici C, Sessa E, D'Aleo G, Corallo F, Lo Buono V, Venuti G, Bramanti P, Marino S Abstract PURPOSE: Multiple sclerosis (MS) is a neurodegenerative and autoimmune disease, which can significantly affect not only the quality of life (QoL) of affected people but also...
Related ArticlesReduced hippocampus and amygdala volumes in antisocial personality disorder. J Clin Neurosci. 2020 May;75:199-203 Authors: Kaya S, Yildirim H, Atmaca M Abstract In the present paper, we aimed to investigate hippocampus and amygdala volumes in a group of patients with antisocial personality disorder and hypothesized that hippocampus and amygdala volume alterations would be observed. It was measured hippocampus and amygdala volumes of twenty...
Related ArticlesDe novo thalamic arteriovenous malformation in a boy with a brainstem cavernous malformation. J Clin Neurosci. 2020 Apr 21;: Authors: Lopez-Rivera V, Sheriff FG, Sandberg DI, Blackburn S, Dannenbaum M, Sheth SA, Day AL, Chen PR Abstract Brain arteriovenous malformations (bAVMs) have long been considered to be congenital, developing between the third and eighth weeks of embryogenesis. However, cases reporting their de novo formation suggest...
Related ArticlesValidation of a new olfactory test for Chinese Parkinson's disease patients. J Clin Neurosci. 2020 Apr 21;: Authors: Cao M, Wang N, Zheng P, Gu Z, Chan P Abstract INTRODUCTION: Hyposmia is a common non-motor symptom in Parkinson's disease (PD) and has been used to assist PD diagnosis and early screening of prodromal patients. Although the Brief Smell Identification Test (B-SIT) is the most commonly used olfactory test, its utility was...
Related ArticlesInterpretation of lumbar cerebrospinal fluid leukocytosis after cranial surgery: The relevance of aseptic meningitis. J Clin Neurosci. 2020 Apr 21;: Authors: Craven CL, Asif H, Curtis C, Thompson SD, D'Antona L, Ramos J, Thorne L, Watkins LD, Toma AK Abstract Raised white cell count (WCC) in lumbar CSF is a commonly used marker of meningitis. The effect of cranial neurosurgery per se on lumbar WCC is not established. At this single centre,...
Related ArticlesCortical bone trajectory technique's outcomes and procedures for posterior lumbar fusion: A retrospective study. J Clin Neurosci. 2020 Apr 21;: Authors: Petrone S, Marengo N, Ajello M, Lavorato A, Penner F, Cofano F, Zenga F, Garbossa D Abstract Cortical Bone Trajectory screws allow a limited soft tissue dissection with mechanical properties comparable to traditional pedicle screws. However, clinical results are still reported on limited...
Related ArticlesThe role of opening CSF pressure in response to treatment for idiopathic intracranial hypertension (IIH). J Clin Neurosci. 2020 Apr 21;: Authors: Togha M, Martami F, Rahmanzadeh R, Ghorbani Z, Refaeian F, Behbahani S, Panahi P, Moghadam NB, Nafissi S, Shahbazi M Abstract The aim of the current study was to assess the risk factors, clinical symptoms and Cerebrospinal fluid (CSF) pressure of idiopathic intracranial hypertension (IIH) with...
Investigation the miRNA146a and miRNA155 gene expression levels in patients with multiple sclerosis.
Related ArticlesInvestigation the miRNA146a and miRNA155 gene expression levels in patients with multiple sclerosis. J Clin Neurosci. 2020 Apr 21;: Authors: Shademan B, Nourazarian A, Nikanfar M, Biray Avci C, Hasanpour M, Isazadeh A Abstract Multiple sclerosis (MS) is a chronic inflammatory disease and the most common neurodegenerative status. MicroRNAs play an important role in macrophage response to inflammatory processes, and alterations in miRNA...
Related ArticlesEmbolization of carotid-cavernous fistulas: A technical note on simultaneous balloon protection of the internal carotid artery. J Clin Neurosci. 2020 Apr 21;: Authors: Zeineddine HA, Lopez-Rivera V, Conner CR, Sheriff FG, Choi PA, Inam ME, Cochran J, Chen PR Abstract A carotid-cavernous fistula (CCF) is an abnormal connection between the carotid circulation and the cavernous sinus. Treatment of CCFs often consists of obliteration of the...
Related ArticlesThe effect of bioactive glasses on spinal fusion: A cross-disciplinary systematic review and meta-analysis of the preclinical and clinical data. J Clin Neurosci. 2020 Apr 21;: Authors: Cottrill E, Pennington Z, Lankipalle N, Ehresman J, Valencia C, Schilling A, Feghali J, Perdomo-Pantoja A, Theodore N, Sciubba DM, Witham T Abstract Pseudarthrosis following spinal fusion is correlated with poorer patient outcomes and consequently is an...
Related ArticlesIntracranial peripherally enhancing lesions in cardiac transplant recipients: A rare case series and literature review. J Clin Neurosci. 2020 Apr 21;: Authors: Kweh BTS, Lee HQ, Tee JW Abstract Intracranial peripherally enhancing lesions in immunosuppressed solid organ transplant recipients represent a unique diagnostic and management dilemma due to the vast array of differentials that demand consideration. Diagnosis of the underlying...
Related ArticlesHospital-acquired conditions occur more frequently in elective spine surgery than for other common elective surgical procedures. J Clin Neurosci. 2020 Apr 21;: Authors: Horn SR, Segreto FA, Alas H, Bortz C, Jackson-Fowl B, Brown AE, Pierce KE, Vasquez-Montes D, Egers MI, Line BG, Oh C, Moon J, De la Garza Ramos R, Vira S, Diebo BG, Frangella NJ, Stekas N, Shepard NA, Horowitz JA, Hassanzadeh H, Bendo JA, Lafage R, Lafage V, Passias PG Abstract...
Related ArticlesExploring eye movements of Parkinson's disease patients performing the Judgement of line orientation test. J Clin Neurosci. 2020 Apr 21;: Authors: Alamri Y, Dalrymple-Alford J, MacAskill M, Anderson TJ Abstract INTRODUCTION: Parkinson's disease (PD) patients are reported to score significantly lower on the Judgement of Line Orientation (JLO) test compared with controls. The traditional method of scoring JLO ignores potentially interesting...
Related ArticlesEPO treatment does not alter acute serum profiles of GFAP and S100B after TBI: A brief report on the Australian EPO-TBI clinical trial. J Clin Neurosci. 2020 Apr 21;: Authors: Hellewell SC, Conquest A, Little L, Vallance S, Board J, Bellomo R, Cooper DJ, Morganti-Kossmann MC Abstract PURPOSE: To determine the diagnostic and prognostic value of glial fibrillary acidic protein (GFAP) and S100B after traumatic brain injury (TBI) in an Erythropoietin...
Related ArticlesSerum alpha-1 antitrypsin in acute ischemic stroke: A prospective pilot study. J Clin Neurosci. 2020 Apr 20;: Authors: Mahta A, Yaghi S, Reznik ME, Thompson BB, Wendell LC, Rao S, Potter NS, Dakay KB, Cutting S, Mac Grory B, Burton T, Saad A, Sacchetti DC, Stretz C, El Jamal S, Mahmoud LN, Moody S, Murray K, Costa S, Sellke FW, Kamel H, Furie KL Abstract BACKGROUND: Alpha-1 antitrypsin (AAT) is a potent anti-protease enzyme which may...
Related ArticlesHybrid mechanical thrombectomy for acute ischemic stroke using an intermediate aspiration catheter and Trevo stent simultaneously. J Clin Neurosci. 2020 Apr 20;: Authors: Kim SH, Lee H, Kim SB, Kim ST, Baek JW, Heo YJ, Jeong HW, Kim HJ, Park JH, Kim JS, Jin SC Abstract PURPOSE: To overcome the limitations of traditional mechanical thrombectomy (MT), including catheter aspiration and stent retrievers, such as thrombus fragmentation or...
Related ArticlesGender differences in the 3-month utilization of nonoperative therapies prior to primary lumbar microdiscectomy. J Clin Neurosci. 2020 Apr 20;: Authors: Davison MA, Lilly DT, Moreno J, Bagley C, Adogwa O Abstract Patients with lumbar intervertebral disc herniation classically trial a brief course of conservative management prior to microdiscectomy surgery. Gender differences have previously been identified in the selection and symptomatic...
Related ArticlesCSF levels of a set of neurotrophic factors (brain-derived neurotrophic factor, nerve growth factor) and neuropeptides (neuropeptide Y, galanin) in epileptic children. J Clin Neurosci. 2020 Apr 20;: Authors: Tekgul H, Serin HM, Simsek E, Kanmaz S, Gazeteci H, Azarsiz E, Ozgur S, Yilmaz S, Aktan G, Gokben S Abstract This paper aims to investigate the possible roles of a set of neurotrophic factors (brain-derived neurotrophic factor-BDNF,...
Related ArticlesPosterior spinal fusion for severe kyphoscoliosis in a Loeys-Dietz syndrome patient with a large syringomyelia. J Clin Neurosci. 2020 Apr 20;: Authors: Uehara M, Ito K, Kosho T, Kuraishi S, Oba H, Hatakenaka T, Ikegami S, Takizawa T, Munakata R, Kubota M, Takahashi J Abstract Spinal deformity is a characteristic feature of Loeys-Dietz syndrome (LDS). Surgical correction in LDS is indicated when the deformity is progressive to avoid neurological...
Association between elevated cerebrospinal fluid D-dimer levels and delayed cerebral ischaemia after aneurysmal subarachnoid haemorrhage. J Clin Neurosci. 2020 Apr 19;: Authors: Jayamanoharan S, Mangum JE, Stylli S, Ziogas J, Adamides AA Abstract Delayed cerebral ischaemia (DCI) after aneurysmal subarachnoid haemorrhage (aSAH) is a major contributor to morbidity and mortality. It is currently not possible to reliably predict patients at risk of DCI after...
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Είναι αλήθεια πως η γνώση μίας ή περισσότερων ξένων γλωσσών, μπορεί να εξασφαλίσει πολλαπλά οφέλη σε επαγγελματικό επίπεδο, αναφορικά με το κοινωνικό κύρος και τον τρόπο ζωής συνολικά. Ωστόσο, μας κάνει εξυπνότερους; Το Ίδρυμα Brain and Mind του Πανεπιστημίου Western αποφάσισε να δώσει την απάντηση. Στη σχετική έρευνα, περισσότεροι από 11.000 συμμετέχοντες από όλο τον κόσμο κλήθηκαν να ολοκληρώσουν 12 διαδικτυακές δοκιμασίες γνώσεων που αξιολογούσαν τη λογική, τη μνήμη, την ικανότητα προγραμματισμού,...
Mon Apr 27, 2020 11:20
Νέα έρευνα που πρόκειται να παρουσιαστεί στο Πανευρωπαϊκό Συνέδριο Κλινικής Μικροβιολογίας και Λοιμώξεων (ECCMID), προσκομίζει σημαντικά ευρήματα σχετικά με τον καρκίνο του παχέος εντέρου και τον τρόπο που συνδέεται με βακτηριαιμίες από συγκεκριμένα αναερόβια βακτήρια. Αναερόβια είναι τα βακτήρια που δεν απαιτούν οξυγόνο για την ανάπτυξή τους και ευδοκιμούν σε διάφορα περιβάλλοντα, συμπεριλαμβανομένου του ανθρώπινου εντέρου, τα οποία συνήθως δεν προκαλούν άμεσα λοιμώξεις. Προηγούμενες μελέτες έχουν...
Mon Apr 27, 2020 08:15
Οι τύποι βακτηρίων στον κόλπο της εγκύου μπορεί να υποδείξει την πιθανότητα πρόωρου τοκετού, διατείνεται νέα μελέτη. Επιπλέον, τα ευρήματα έδειξαν πως γυναίκες που γέννησαν πρόωρα είχαν μεγαλύτερη ποικιλότητα στο μικροβίωμα του κόλπου τους σε σύγκριση με εκείνες που γέννησαν στους εννέα μήνες. Τα ευρήματα, που δημοσιεύτηκαν στο Frontiers in Microbiology, βασίστηκαν στη μελέτη περισσότερων από 3.000 δειγμάτων από 400 γυναίκες. Σύμφωνα με τη συγγραφέα της μελέτης, Marina Sirota, επίκουρη καθηγήτρια...
Fri Apr 24, 2020 14:11
Στην Ιατρική Βιβλιογραφία και στα μέσα μαζικής ενημέρωσης αναφέρεται συχνά ότι ο ιός SARS-CoV-2, που προκαλεί τη νόσο COVID-19, παρουσιάζει συχνά μεταλλάξεις. Προκειμένου να διευκρινιστεί όσο γίνεται περισσότερο το θέμα αυτό, οι Καθηγητές του Εθνικού και Καποδιστριακού Πανεπιστημίου Αθηνών Ιωάννης Τρουγκάκος, Ευστάθιος Καστρίτης, Δημήτρης Παρασκευής και Θάνος Δημόπουλος ανασκόπησαν τα μέχρι τώρα δεδομένα. Οι πρωτεΐνες είναι το κύριο δομικό-λειτουργικό στοιχείο όλων των οργανισμών της βιόσφαιρας....
Fri Apr 24, 2020 10:13
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