This is an ongoing project, so you can use the weekend to grab your supplies as part of your bi-weekly grocery shopping trip. Then, check back Monday for the first project!It's time to do some science. (Gustavo Fring/Pexels/)Throughout elementary, middle, and high school, science class was always the place we could count on having a little fun. Where else would we get the chance to build a volcano with vinegar and baking soda, conjure electricity from a pickle, or launch potatoes out of an air cannon?Right...
Mon Apr 27, 2020 20:58
Keep it tight with a trim. (Amazon/)Those of you who keep your facial hair from getting too scruffy know that it takes some effort—and a good trimmer makes all the difference. No one wants irritated skin or uneven edges. Surprisingly, there are a lot of beard trimmers that will make you feel like it’s not worth the upkeep. We’ve rounded up three of our favorites that will make your life easy. Take your look up a notch.Get grooming. (Amazon/)This beard trimmer is on the pricier side, but there is...
Fri Apr 24, 2020 18:45
Brazil has hosted some of the largest concert events in history. Back on December 31, 1994, Rod Stewart played to an estimated crowd of more than 3.5 million people to ring in the new year. Last night, however, more than 12 million people attended a performance by rapper Travis Scott. It wasn’t in a park or on a beach, however—it all happened inside the video game world of Fortnite.Typically, Fortnite is a battle royale-style game in which players drop simultaneously onto an island, compete to find...
Fri Apr 24, 2020 18:26
All the free seltzer and coffee in the world won't make up for a bad office chair. (Raj Rana via Unsplash/)With all the time we spend on our computers, it’s easy to subject your back and neck to rigid, uncompromising office chairs. If you’re doing to buckle down and get to work, you can at least have all the support and comfort that you need.We’ve planted down in a wide variety of office chairs to pinpoint those that meet both the needs of individuals and the vibe of office cultures. Here are some...
Fri Apr 24, 2020 17:18
You choose how short you want to go. (Jonathan Weiss via Unsplash/)Spring cleaning can take many forms. One classic way to wash away the woes of winter is to buzz your head. There are few things more satisfying than taking a shaver to the cranium and giving your hair the old heave-ho. You’ll feel brand new—lighter, cooler, and smoother to the touch. You won’t have to check your hair in the mirror, because...you’ll barely have any. But one shouldn’t shave their head with just any electric shaver....
Fri Apr 24, 2020 15:48
Since post-treatment PSA values were first introduced into clinical practice in the 1980s, clinicians have grappled with interpretation of these values. Two consensus conferences, ASTRO in 1996 [1] and Phoenix in 2005 [2], defined biochemical failure after external beam radiotherapy (EBRT), but neither included data from patients treated with androgen deprivation therapy (ADT) or brachytherapy [3]. Neither consensus conference attempted to define cure and neither definition is readily comparable...
Mon Apr 27, 2020 03:00
In 2019, approximately 174,650 men will be diagnosed with prostate cancer in the United States.[1] Recent estimates have demonstrated that number to be more than twofold higher in Europe.[2] The Prostate Testing for Cancer and Treatment (ProtecT) trial suggested that conventionally fractionated radiation therapy (CFRT) (1.8-2 Gy, 5 days per week, for 8-9 weeks to a total dose of 70-81 Gy) offers similar oncologic outcomes with improved quality of life when compared to radical prostatectomy.[3,4]...
Mon Apr 27, 2020 03:00
Although we previously reported that weekly prostate SABR had better bowel and urinary QOL compared to EOD, the updated results show no difference in late toxicity, QOL, BF, or PSA kinetics. Patients should be counselled that QW SABR reduces short-term toxicity compared to QW SABR.
Mon Apr 27, 2020 03:00
With the current Covid 19 pandemic, healthcare systems are severely strained1–3. So far, infection and severe complications have been less common in children4. Nevertheless the pandemic is expected to have an impact on the capacity to deliver paediatric radiotherapy, particularly where general anaesthesia is required, due toshortages ofpersonnel,protective equipment, ventilatorsand machine time, as well as coping infected children and families5,6. Sudden shortage of resources may also occur during...
Sun Apr 26, 2020 03:00
The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-COVID 19 has rapidly taken on pandemic proportions, with nearly 2.400.000 people infected and 165.000 dead, at the time writing (https://www.ecdc.europa.eu/).
Sat Apr 25, 2020 03:00
As the COVID-19 pandemic surges, concerns grow over serious health conditions. Since the healthcare resources are highly stretched taking care of the COVID-19 patients, other parts of the Iranian healthcare system are critically influenced. Cancer care is specifically facing innumerable challenges in our country, putting the clinical decision-makers in a parlous risk of mismanagement, ranging from the risk of the exposure to COVID-19 to the harm caused by the delayed treatment. Regarding the therapies,...
Sat Apr 25, 2020 03:00
The use of chemotherapy (CHT) concomitant with (radiotherapy) RT in locally advanced non-small cell lung cancer (NSCLC) has been demonstrated to prolong overall survival (OS) compared with sequential RT–CHT or with RT alone [1,2]. In one study, radiation dose escalation up to 74 Gy/37 fractions in concomitant RT–CHT was detrimental for OS compared with the standard 60 Gy /30 fractions [3]. A combination of several factors may explain the counterintuitive harmful effects of the higher radiation dose...
Fri Apr 24, 2020 03:00
Volumetric modulated arc therapy (VMAT) is an advanced technique that can deliver highly conformal radiation dose and reduce overall treatment time. However, due to high degree of complexity and dose gradients, the requirement of delivery accuracy has increased for VMAT. Pre-treatment quality assurance (QA) and image guidance can detect certain errors [1–4], but they are not sufficient to detect intra-fractional movement of the patient, change of patient’s anatomy or the errors during VMAT, and image...
Fri Apr 24, 2020 03:00
With great interest we read the recommendations by Guckenberger and colleagues [1] on radiation treatment of lung cancer patients in times of COVID-19, which were endorsed by ESTRO and ASTRO. The authors should be applauded for their timely and constructive guidance. Such recommendations are highly needed in these unprecedented times and we strongly support their initiative.
Fri Apr 24, 2020 03:00
The recent outbreak of the novel Coronavirus SARS-CoV-2 has dramatically hit many hospitals, involving an overwhelming number of patients. Most of them suffered a change in their diagnostic and therapeutic program. Cancer patients represent one of the most fragile groups due to their compromised clinical conditions exasperated by age, comorbidities, immunosuppression status and by the number of hospital visits requested for the radiation therapy course.
Fri Apr 24, 2020 03:00
Background:Biomarker accuracy for Alzheimer disease (AD) is uncertain.Purpose:To summarize evidence on biomarker accuracy for classifying AD in older adults with dementia.Data Sources:Electronic bibliographic databases (searched from January 2012 to November 2019 for brain imaging and cerebrospinal fluid [CSF] tests and from inception to November 2019 for blood tests), ClinicalTrials.gov (to November 2019), and systematic review bibliographies.Study Selection:English-language studies evaluating the...
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In this issue, 3 systematic reviews summarize the evidence on brief cognitive tests to distinguish Alzheimer's dementia from mild cognitive impairment or normal cognition, biomarker testing for neuropathologic Alzheimer's, and prescription drugs and supplements in the treatment of Alzheimer's dementia. The editorialists discuss the findings and hope for more options for preventing, diagnosing, treating, and Alzheimer's dementia.
00:49
Background:Studies have reported that natriuretic peptides provide prognostic information for emergency department (ED) syncope.Objective:To evaluate whether adding N-terminal pro–B-type natriuretic peptide (NT-proBNP) to the Canadian Syncope Risk Score (CSRS) improves prediction of 30-day serious adverse events (SAEs).Design:Prospective cohort study.Setting:6 EDs in 2 Canadian provinces.Participants:1452 adult ED patients with syncope.Intervention:Serum NT-proBNP was measured locally at 1 site and...
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Background:Effects of drug treatment of clinical Alzheimer-type dementia (CATD) are uncertain.Purpose:To summarize evidence on the effects of prescription drugs and supplements for CATD treatment.Data Sources:Electronic bibliographic databases (inception to November 2019), ClinicalTrials.gov (to November 2019), and systematic review bibliographies.Study Selection:English-language trials of prescription drug and supplement treatment in older adults with CATD that report cognition, function, global...
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Background:The accuracy and harms of brief cognitive tests for identifying clinical Alzheimer-type dementia (CATD) are uncertain.Purpose:To summarize evidence on accuracy and harms of brief cognitive tests for CATD in older adults with suspected cognitive impairment.Data Sources:Electronic bibliographic databases (from inception to November 2019) and systematic review bibliographies.Study Selection:English-language, controlled observational studies in older adults that evaluated the accuracy of brief...
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Background:The coronavirus disease 2019 pandemic has or threatens to overwhelm health care systems. Many institutions are developing ventilator triage policies.Objective:To characterize the development of ventilator triage policies and compare policy content.Design:Survey and mixed-methods content analysis.Setting:North American hospitals associated with members of the Association of Bioethics Program Directors.Participants:Program directors.Measurements:Characteristics of institutions and policies,...
Fri Apr 24, 2020 03:00
These authors share thoughts about discriminatory approaches to the allocation of resources during health care catastrophes, such as the COVID-19 pandemic. They argue that, although prioritization of resources is critical, fairness requires giving each patient his or her due based on clinical criteria applied to the individual rather than assumptions that favor or disfavor groups.
Fri Apr 24, 2020 03:00
Abstract Purpose of Review This review overviews perioperative stroke as it pertains to specific surgical procedures. Recent Findings As awareness of perioperative stroke increases, so does the opportunity to potentially improve outcomes for these patients by early stroke recognition and intervention. ...
Mon Apr 27, 2020 03:00
Writing-up statistical results is as important as selecting the correct statistical test to apply to your data. To convey the message to the readers, statistics need to be reported clearly and in a comprehensible way. Individual academic journals may have slightly different formats and guidelines for how results should be reported. To facilitate the review and editorial process for publication in the British Journal Oral and Maxillofacial Surgery (BJOMS) – and bearing in mind that most submissions...
Mon Apr 27, 2020 03:00
The standard of care for head and neck reconstruction is microvascular free-tissue transfer. Various techniques of soft tissue, free-flap design have previously been described. Patient-specific planning and 3D printing have changed practice in bony reconstruction, but are not currently used in soft tissue head and neck reconstruction. We present the first report of Personalised pAtient-specific plaNning of SOFt tissue recOnStruction, the “PANSOFOS” flap, and aim to prove that the technique has a...
Sun Apr 26, 2020 03:00
Chronic mucocutaneous candidiasis is a rare disorder that is characterised by chronic or recurrent superficial candida infection of skin, nails, and mucous membranes. We describe such a case in a young boy who failed to respond to conventional therapy. It highlights the important role of the dental team in assessment, treatment, and onwards referral.
Sun Apr 26, 2020 03:00
Intermaxillary fixation (IMF) is an integral part of the management of facial fractures. A properly achieved IMF will provide a perfect occlusion in the postoperative period. There are various techniques already published for achieving IMF, showing their merits and demerits. The aim of this letter is to add a quick and unique technique of achieving of IMF by simply using two 24-gauge wires (Fig. 1).
Sun Apr 26, 2020 03:00
There are several techniques for arthroscopic discopexy reported in the literature. The most widespread is the McCain technique,1 which is technically simple but has some disadvantages. Zhang et al2 proposed modifications to it, which improved the technique, but made it extremely complex and therefore not a feasible option for most surgeons. We aim to describe a new technique that allows for repositioning of the disc, is similar to the modified technique,2 but technically simpler than the original.
Sat Apr 25, 2020 03:00
At the end of 2019, a novel severe acute respiratory syndrome (SARS) coronavirus (CoV), named SARS-CoV-2, was identified. Since then, the spread of coronavirus disease 2019 (COVID-19) has progressively involved countries worldwide, with the World Health Organization (WHO) stating that it had reached pandemic status.1,2 Older adults and patients with pre-existing comorbidities including cancer, particularly those on treatments that cause immunosuppression, have a higher risk of life-threatening consequences.
Fri Apr 24, 2020 03:00
11 Health, a medtech company based in the UK and California, has offered 12 weeks of free access to the Alfred SmartCare Platform, which allows for virtual peer and nursing support for patients with severe chronic digestive disorders, such as inflammatory bowel disease, Crohn’s disease, and colorectal cancer. The offer is the company’s response to the COVID-19 pandemic. The pandemic has meant that many patients are self-isolating and now have to focus more on managing their conditions at home. ...
Mon Apr 27, 2020 23:46
As the current COVID-19 pandemic continues to rage, there is movement toward restarting life under a “new normal”. The virus may be with us for a long time, but widespread, rapid, and accurate testing may be a way forward. Knowing which individuals have to quarantine themselves and which are free of the virus would go a long way toward a rapid recovery of economic and social activities. Researchers at the University of Illinois at Urbana-Champaign have now developed a cheap, sensitive, and accurate...
Mon Apr 27, 2020 19:13
Lungpacer Medical, based in Vancouver, Canada, announced that its Diaphragm Pacing Therapy (DPT) System received FDA Emergency Use Authorization for use in weaning COVID-19 patients off of ventilators. Patients on prolonged mechanical ventilation may experience diaphragm disuse atrophy and ventilator-induced diaphragmatic dysfunction (VIDD), which makes it harder for patients to breathe on their own and increases the amount of time required on ventilation. The Lungpacer DPT System...
Mon Apr 27, 2020 17:57
Add the National Aeronautics and Space Administration (NASA) to the list of groups that have re-focused their efforts to help combat the global coronavirus pandemic. The same organization that put men on the moon has now developed a prototype ventilator that passed simulated human testing last week at the Icahn School of Medicine at Mount Sinai in New York City, an epicenter of COVID-19 in the U.S. According to NASA, the high-pressure ventilator, named VITAL (Ventilator Intervention Technology...
Mon Apr 27, 2020 16:18
All sorts of medical procedures have to wait to be performed due to the ongoing COVID-19 pandemic. Since some procedures are done in several steps, often separated by weeks or months, there are patients out there that cannot complete the next steps of their therapies. Cochlear implants, which stimulate the auditory nerve to produce hearing in people with profound hearing loss, have to first be implanted in a surgical procedure and then switched on and fine tuned during a separate visit to an audiologist....
Fri Apr 24, 2020 19:42
MIT engineers have developed a way of creating shirts and other clothing items that are embedded with tiny electronic sensors capable of measuring the heart and respiration rates, temperature, and movement. Other vital signs can be added by utilizing additional sensor types. The technology will allow physicians to monitor their patients closely throughout the day, potentially including 12-lead ECG capabilities that can comprehensively detect a wide variety of cardiovascular conditions. Of course,...
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