Journal of Clinical Sleep Medicine, Ahead of Print.
Fri Apr 24, 2020 10:00
Journal of Clinical Sleep Medicine, Ahead of Print.
Fri Apr 24, 2020 10:00
Journal of Clinical Sleep Medicine, Ahead of Print.
Fri Apr 24, 2020 10:00
Journal of Clinical Sleep Medicine, Ahead of Print.
Fri Apr 24, 2020 10:00
ABSTRACT Introduction Supine positioning during late pregnancy causes dramatic compression of maternal abdominal vasculature and is a risk factor for stillbirth. The azygos vein has been shown to provide collateral circulation in this scenario. There are many well‐known anatomical differences in abdominal vasculature between the left and right sides of the body. However, the effect of left and right positioning in pregnancy has not been well studied. Materials and Methods After obtaining...
Thu Apr 23, 2020 18:18
To have oropharyngeal cancer once and be cured without radiation therapy is more than luck. It is the sign of...
Thu Apr 23, 2020 05:49
Otolaryngologist Fernando Gomez-Rivera, MD, has joined the Department of Otorhinolaryngology-Head and Neck Surgery at McGovern Medical School at UTHealth. Dr....
Thu Apr 23, 2020 05:46
The Houston medical community attended an open house last December to celebrate the move of the Texas Center for Facial...
Thu Apr 23, 2020 05:43
Abstract Introduction To evaluate the differences in the associations of combinations of co-existent osteopenia, obesity, and/or sarcopenia with insulin resistance (IR) according to different criteria of obesity. Materials and methods Among 4500 Korean men and postmenopausal women who were aged ≥ 50 years and did not have diabetes mellitus, osteopenia,...
Sat Apr 25, 2020 03:00
Traditional infection-control and public health strategies rely heavily on early detection of disease to contain spread. When Covid-19 burst onto the global scene, public health officials initially deployed interventions that were used to control severe acute respiratory syndrome (SARS) in 2003,…
Fri Apr 24, 2020 03:00
It’s a sunny Sunday in San Francisco as I tackle overdue clinic notes and Covid-19 sweeps the planet. I am scheduled to speak in 10 other states over the coming weeks, and as a healthy, middle-aged physician from a region with growing numbers of infections, I’m as likely to be a vector as a victim.…
Tue Apr 07, 2020 03:00
"Doctor, should we activate the sepsis protocol?" my medical assistant asked with obvious concern. I triaged the patient in question. The metrics that had caused alarm at intake were tachycardia and tachypnea, but there was no fever or hypotension in this middle-aged woman. On exam, she was indeed…
Tue Apr 07, 2020 03:00
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Aim:Keratin 6A is a type II cytokeratin which is important in forming nail bed, filiform papillae, the epithelial lining of oral mucosa, and esophagus; recently, keratin 6A was found hyperexpressed in different types of cancer. But, the biological function of keratin 6A in lung adenocarcinoma still remains unclear. Therefore, in current study, we investigated the biological role of keratin 6A in lung adenocarcinoma.Methods:By...
Fri Apr 24, 2020 12:52
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Background:Lower-dose cone-beam computed tomography protocols for image-guided radiotherapy may permit target localization while minimizing radiation exposure. We prospectively evaluated a lower-dose cone-beam protocol for central nervous system image-guided radiotherapy across a multinational pediatrics consortium.Methods:Seven institutions prospectively employed a lower-dose cone-beam computed tomography central...
Fri Apr 24, 2020 12:50
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Radiotherapy is one of the most important cancer treatments, but its response varies greatly among individual patients. Therefore, the prediction of radiosensitivity, identification of potential signature genes, and inference of their regulatory networks are important for clinical and oncological reasons. Here, we proposed a novel multiple genomic fused partial least squares deep regression method to simultaneously...
Fri Apr 24, 2020 12:47
Journal of Cutaneous Medicine and Surgery, Ahead of Print.
Fri Apr 24, 2020 15:51
Thyroid, Ahead of Print.
Fri Apr 24, 2020 10:00
Thyroid, Ahead of Print.
Fri Apr 24, 2020 10:00
Thyroid, Ahead of Print.
Fri Apr 24, 2020 10:00
I stand in the parking lot of our emergency department and watch three men on horseback trot up the shoulder of the highway. They wear bandanas over their faces, a traditional accessory here in northwest New Mexico, where spring is wind-and-dust season. Normally, this spot is where we peek out of…
Fri Apr 24, 2020 03:00
To the Editor: Kidney-transplant recipients appear to be at particularly high risk for critical Covid-19 illness due to chronic immunosuppression and coexisting conditions. At Montefiore Medical Center, we identified 36 consecutive adult kidney-transplant recipients who tested positive for Covid-19…
Fri Apr 24, 2020 03:00
This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors’ clinical recommendations. A 73-year-old man with…
Fri Apr 24, 2020 03:00
The first reported case of coronavirus disease 2019 (Covid-19) in the United States was diagnosed in a resident of Snohomish County, Washington, on January 20, 2020. In late February, an outbreak was identified in a skilled nursing facility in neighboring King County; morbidity and mortality among…
Fri Apr 24, 2020 03:00
To rapidly communicate short reports of innovative responses to Covid-19 around the world, along with a range of current thinking on policy and strategy relevant to the pandemic, the Journal has initiated the Covid-19 Notes series. Treating patients in New York City, the global epicenter of the…
Fri Apr 24, 2020 03:00
The rapid spread of SARS-CoV-2, a novel coronavirus that emerged in late 2019, and the resulting Covid-19 disease has been labeled a Public Health Emergency of International Concern by the World Health Organization. What physicians need to know about transmission, diagnosis, and treatment is the…
Thu Apr 23, 2020 03:00
Programming a Cochlear Implant for Tinnitus Suppression. J Am Acad Audiol. 2020 Apr;31(4):302-308 Authors: Perreau A, Tyler R, Mancini PC Abstract BACKGROUND: Electrical stimulation of the cochlea to treat tinnitus has been explored for decades. However, few studies have investigated the most salient programming parameters for tinnitus suppression in cochlear implant (CI) patients. PURPOSE: The purpose of this study was to review the...
Sat Apr 25, 2020 05:55
Quantifying the "Meaning of Life". J Am Acad Audiol. 2020 Apr;31(4):245 Authors: Jacobson GP PMID: 32323290 [PubMed - in process]
Sat Apr 25, 2020 05:55
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused clusters of severe respiratory illness in Wuhan, China, in late 2019. By January 2020, the virus had been isolated and sequenced, which revealed close relationships to coronaviruses such as SARS-CoV-1 and MERS-CoV. As of March 31,…
Tue Apr 14, 2020 03:00
Fibroblast activation protein (FAP) has emerged as an interesting molecular target used in the imaging and therapy of various types of cancers. Gallium-68–labeled chelator-linked FAP inhibitors (FAPIs) have been successfully applied to positron emission tomography (PET) imaging of various tumor types. To broaden the spectrum of applicable PET tracers for extended imaging studies of FAP-dependent diseases, we herein report the radiosynthesis and preclinical evaluation of an 18F–labeled glycosylated...
Sat Apr 25, 2020 00:33
Purpose: We aimed to conduct a systematic review and meta-analysis of studies reporting the performance of radioactive iodine therapy (131-I therapy) in differentiating thyroid cancer (DTC) patients requiring a completion treatment following lobectomy. We also evaluated the response to 131-I therapy according to 2015ATA guidelines and the adverse events. Methods: A specific search strategy was designed to find articles evaluating the use of I-131 in patients with evidence of DTC after lobectomy....
Sat Apr 25, 2020 00:33
Introduction: Gastrin Releasing peptide receptors (GRPRs) are potential molecular imaging targets in a variety of tumors. Recently, a 68Ga-labelled antagonist to GRPRs, NeoBOMB1, was developed for PET. We report on the outcome of a Phase I/IIa clinical trial (EudraCT 2016-002053-38) within the EU-FP7 project Closed-loop Molecular Environment for Minimally Invasive Treatment of Patients with Metastatic Gastrointestinal Stromal Tumours (‘MITIGATE’) (grant agreement number 602306) in patients with oligometastatic...
Sat Apr 25, 2020 00:33
Prostate specific membrane antigen (PSMA) targeting Positron Emission Tomography (PET) imaging is becoming the reference standard for prostate cancer (PC) staging, especially in advanced disease. Yet, the implications of PSMA-PET derived whole-body tumor volume for overall survival are poorly elucidated to date. This might be due to the fact that (semi-) automated quantification of whole-body tumor volume as PSMA-PET biomarker is an unmet clinical challenge. Therefore, a novel semi-automated software...
Sat Apr 25, 2020 00:33
C-X-C chemokine receptor 4 is a transmembrane chemokine receptor involved in growth, survival, and dissemination of cancer, including aggressive B-cell lymphoma. Magnetic resonance imaging (MRI) is the standard imaging technology for central nervous system involvement of B-cell lymphoma and provides high sensitivity but moderate specificity. Therefore, novel molecular and functional imaging strategies are urgently required. Methods: In this proof-of-concept study, 11 patients with lymphoma of...
Sat Apr 25, 2020 00:33
Exp Clin Endocrinol DiabetesDOI: 10.1055/a-1088-1187Thyroid hormone (TH) is essential for the regulation of many physiological processes, especially growth, organ development, energy metabolism and cardiovascular effects. TH acts via the TH receptors (TR) α and β. By binding to thyroid hormone responsive elements (TREs) on the DNA, TRs regulate expression of TH target genes. Thus, TRs are mainly characterized ...
Fri Apr 24, 2020 02:00
Fri Apr 24, 2020 03:00
Abstract Latino adolescent and young adult (AYA) cancer survivors represent a growing population given the changing demographics in the USA. They experience significant healthcare disparities and barriers that warrant age-specific and culturally appropriate interventions to improve their clinical and psychosocial outcomes. This single-arm pilot study evaluated a novel intervention – a photonovela – on its ability to educate Latino AYA survivors and their family members and engage...
Fri Apr 24, 2020 03:00
Objectives: The brain is a rare site for sarcoma metastases. Sarcoma’s radioresistance also makes standard whole-brain radiotherapy less appealing. We hypothesize that stereotactic radiation techniques (stereotactic radiosurgery [SRS]/stereotactic fractionated radiotherapy [FSRT]) may provide effective local control. Materials and Methods: This single-institution retrospective analysis evaluated our experience with linear acceleator-based SRS/FSRT for sarcoma brain metastases. Time to event...
Sat Apr 25, 2020 01:45
Objectives: Although current guidelines continue to recommend trimodality therapy for stage II to III rectal cancers, a lower incidence of local recurrence has been observed in patients with upper rectal tumors, including those in the rectosigmoid. In practice, patients with upper rectal tumors may not be receiving all 3 modalities of therapy. Patterns of care for patients with rectosigmoid cancers have not previously been described. Methods: The National Cancer Database (NCDB) was used to...
Sat Apr 25, 2020 01:45
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