Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Breast cancer has been a worldwide burden of women’s health. Although concerns have been raised for early diagnosis and timely treatment, the efforts are still needed for precision medicine and individualized treatment. Radiomics is a new technology with immense potential to obtain mineable data to provide rich information about the diagnosis and prognosis of breast cancer. In our study, we introduced the workflow...
Wed Apr 29, 2020 13:36
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Objective:This study aimed to explore whether eukaryotic translation elongation factor 1 alpha 2 affected cell proliferation, migration, and apoptosis via regulating the dimethylation of eukaryotic translation elongation factor 1 alpha at lysine 55 in acute myeloid leukemia.Methods:The expressions of eukaryotic translation elongation factor 1 alpha 2 and dimethylation of eukaryotic translation elongation factor...
Wed Apr 29, 2020 13:33
Related ArticlesImpact of adjuvant therapy on survival in patients with myoepithelial carcinoma: A systematic review and individual patient data analysis of 691 patients. Radiother Oncol. 2019 11;140:125-130 Authors: Giridhar P, Gupta P, Mallick S, Upadhyay AD, Rath GK Abstract INTRODUCTION: Myoepithelial carcinoma (MEC) is an extremely rare low grade salivary gland neoplasm [1-4]. A surgical resection is considered as corner stone of therapy. Role...
Wed Apr 29, 2020 13:21
Related ArticlesPancreatic Ductal Adenocarcinoma in Remnant Pancreas after Pancreaticoduodenectomy for Acinar Cell Carcinoma: A Case Report. J Nippon Med Sch. 2019 Dec 03;86(5):279-283 Authors: Nishimura S, Utsumi M, Aoki H, Une Y, Kashima H, Kimura Y, Taniguchi F, Arata T, Katsuda K, Tanakaya K, Sato Y Abstract We report a case of a pancreatic ductal adenocarcinoma (PDAC) in the remnant pancreas of a 78-year-old man after pancreaticoduodenectomy for...
Wed Apr 29, 2020 13:21
Related ArticlesA rare case of multiple and huge simple bone cysts in Wilson's disease. J Orthop Surg (Hong Kong). 2019 May-Aug;27(2):2309499019843141 Authors: Ji JH, Hwang WH, Lee YS, Kim JO Abstract A simple bone cyst is a tumor-like lesion that is not a true neoplasm. It usually presents as a solitary lesion within the proximal humerus and proximal femur. The etiology of simple bone cysts is still to be elucidated. We describe our experience in...
Wed Apr 29, 2020 13:21
Related ArticlesA novel splicing mutation of PTCH1 in a Chinese family with nevoid basal cell carcinoma syndrome. Med Mol Morphol. 2019 Dec;52(4):235-237 Authors: Zhou J, Zhang G, Shi M, Liu Z, Xiao M, Fu S, Gong X, Shi X Abstract Nevoid basal cell carcinoma syndrome (NBCCS) is a rare autosomal dominant disease characterized by the development of multiple jaw keratocysts and basal cell carcinomas (BCC) and accompanied by diverse phenotypes. The establishment...
Wed Apr 29, 2020 13:21
Page 4, Figure 1:
Wed Apr 29, 2020 03:00
Related ArticlesOptical Biopsy: Automated Classification of Airway Endoscopic Findings Using a Convolutional Neural Network. Laryngoscope. 2020 Apr 28;: Authors: Dunham ME, Kong KA, McWhorter AJ, Adkins LK Abstract OBJECTIVES/HYPOTHESIS: Create an autonomous computational system to classify endoscopy findings. STUDY DESIGN: Computational analysis of vocal fold images at an academic, tertiary-care laryngology practice. METHODS: A series...
Wed Apr 29, 2020 17:19
Related ArticlesIsolated Adrenocorticotropic Hormone Deficiency and Primary Hypothyroidism in a Patient Undergoing Long-Term Hemodialysis: A Case Report and Literature Review. Am J Case Rep. 2020 Apr 28;21:e922376 Authors: Ohara N, Kobayashi M, Tuchida M, Koda R, Yoneoka Y, Iino N Abstract BACKGROUND Patients with end-stage renal disease undergoing long-term maintenance hemodialysis are more likely than the general population to exhibit primary hypothyroidism....
Wed Apr 29, 2020 15:21
Related ArticlesIntracranial Gorgon: Surgical Case Report of a Large Calcified Brain Arteriovenous Malformation. Am J Case Rep. 2020 Apr 28;21:e922872 Authors: Florian IA, Popovici L, Timis TL, Florian IS, Berindan-Neagoe I Abstract BACKGROUND Brain arteriovenous malformations (AVMs) are benign intracranial vascular anomalies that, under certain circumstances, may become life-threatening. Diffuse calcifications found in the vessel walls, interposing...
Wed Apr 29, 2020 13:16
Oral administration of bovine lactoferrin accelerates the healing of fracture in ovariectomized rats
Abstract Introduction Lactoferrin has recently been reported for its potent bone growth effects. However, the effects of lactoferrin on the healing process of fragility fracture have not yet been studied, so the purpose of this study is to investigate whether oral administration of lactoferrin can promote the fracture healing in an OVX animal model. Materials and methods...
Wed Apr 29, 2020 03:00
Publication date: May–June 2020Source: Practical Radiation Oncology, Volume 10, Issue 3Author(s):
Wed Apr 29, 2020 13:13
Publication date: May–June 2020Source: Practical Radiation Oncology, Volume 10, Issue 3Author(s):
Wed Apr 29, 2020 13:13
Publication date: May–June 2020Source: Practical Radiation Oncology, Volume 10, Issue 3Author(s):
Wed Apr 29, 2020 13:13
Related ArticlesA retrospective study on comparing the surgery and microneedles radiofrequency and microwaves treatment in axillary osmidrosis. J Dermatolog Treat. 2020 Apr 28;:1-29 Authors: Li Y, Huang Z, Ran L, Wang W, Yu X, Wang R Abstract Objective: To compare the traditional treatment of minimally invasion surgery with the evolving treatments of microneedles radiofrequency and microwaves, this study mainly focused on the clinical efficacy and the...
Wed Apr 29, 2020 15:07
Related ArticlesConducting Clinical Trials During the COVID-19 Pandemic. J Dermatolog Treat. 2020 Apr 28;:1-8 Authors: Collier EK, Hsiao JL, Shi VY Abstract The COVID-19 pandemic has greatly impacted dermatology clinical trial operations due to mandated governmental and institutional shut-downs and newly implemented restrictions. During this unprecedented time, measures should be taken to maintain research conduct compliance while also ensuring the safety...
Wed Apr 29, 2020 15:07
Related ArticlesDegeneration of the Ipsilateral Substantia Nigra and Red Nucleus as Well as Contralateral Dentate Nucleus after Middle Cerebral Artery Infarction. Radiology. 2020 Apr 28;:201009 Authors: Slavova N, Wiest R PMID: 32343214 [PubMed - as supplied by publisher]
Wed Apr 29, 2020 15:09
Related ArticlesComplications Following Percutaneous Image-guided Radiofrequency Ablation of Bone Tumors: A 10-year Dual-Center Experience. Radiology. 2020 Apr 28;:191905 Authors: Cazzato RL, Palussière J, Auloge P, Rousseau C, Koch G, Dalili D, Buy X, Garnon J, De Marini P, Gangi A Abstract Background Percutaneous radiofrequency ablation (RFA) is effective in the management of bone tumors. However, knowledge of the complication rate and risk factors...
Wed Apr 29, 2020 15:09
Related ArticlesThree-dimensional Ultrashort Echo Time MRI for Functional Lung Imaging in Cystic Fibrosis. Radiology. 2020 Apr 28;:192251 Authors: Heidenreich JF, Weng AM, Metz C, Benkert T, Pfeuffer J, Hebestreit H, Bley TA, Köstler H, Veldhoen S Abstract Background In cystic fibrosis (CF), recurrent imaging and pulmonary function tests (PFTs) are needed for the assessment of lung function during disease management. Purpose To assess the clinical...
Wed Apr 29, 2020 15:09
Related ArticlesUS Evaluation of Bone Age in Rural Ecuadorian Children: Association with Anthropometry and Nutrition. Radiology. 2020 Apr 28;:190606 Authors: Nicholas JL, Douglas KE, Waters W, Gallegos Riofrío CA, Chapnick M, Habif DV, True S, Musonza C, Iannotti L Abstract Background Stunted growth and development is a serious global public health problem. A limited number of field measures exist that can be used to evaluate stunting and its underlying...
Wed Apr 29, 2020 15:09
Related ArticlesDentate Nucleus Signal Intensity Increases Following Repeated Gadobenate Dimeglumine Administrations: A Retrospective Analysis. Radiology. 2020 Apr 28;:190246 Authors: Nguyen NC, Molnar TT, Cummin LG, Kanal E Abstract Background Increased cerebral signal intensity (SI) has been reported in patients undergoing MRI with gadolinium-based contrast agents (GBCAs). Published data on gadobenate dimeglumine have been somewhat contradictory....
Wed Apr 29, 2020 15:09
Related ArticlesAdvanced MRI of Liver Fibrosis and Treatment Response in a Rat Model of Nonalcoholic Steatohepatitis. Radiology. 2020 Apr 28;:192118 Authors: Zhou IY, Clavijo Jordan V, Rotile NJ, Akam E, Krishnan S, Arora G, Krishnan H, Slattery H, Warner N, Mercaldo N, Farrar CT, Wellen J, Martinez R, Schlerman F, Tanabe KK, Fuchs BC, Caravan P Abstract Background Liver biopsy is the reference standard to diagnose nonalcoholic steatohepatitis (NASH)...
Wed Apr 29, 2020 15:09
Related ArticlesIn Depth: Determining Optimal Central Venous Catheter Length During Insertion. World J Surg. 2020 Apr 27;: Authors: Hatton GE, Kao LS PMID: 32342132 [PubMed - as supplied by publisher]
Wed Apr 29, 2020 13:08
Related ArticlesThe Effect of High-Frequency Repetitive Transcranial Magnetic Stimulation on Advancing Parkinson's Disease With Dysphagia: Double Blind Randomized Clinical Trial. Neurorehabil Neural Repair. 2019 06;33(6):442-452 Authors: Khedr EM, Mohamed KO, Soliman RK, Hassan AMM, Rothwell JC Abstract We investigate if rTMS has a therapeutic role in the treatment of dysphagia in patients with Parkinson's disease (PD). Material and Methods. Thirty-three...
Wed Apr 29, 2020 13:08
Related ArticlesTemporal Bone Encephaloceles: Utility of Preoperative Imaging. Otolaryngol Head Neck Surg. 2020 Apr 28;:194599820918566 Authors: Worrall DM, Pai A, Garneau JC, Perez ER, Cosetti MK, Smouha EE, Wanna GB Abstract OBJECTIVE: To determine the diagnostic efficacy and clinical value of preoperative computed tomography (CT) and magnetic resonance imaging (MRI) among patients with suspected temporal bone encephaloceles (TBE). STUDY DESIGN:...
Wed Apr 29, 2020 14:06
Related ArticlesInsight into the molecular evidence supporting the remarkable chemotherapeutic potential of Hibiscus sabdariffa L. Biomed Pharmacother. 2020 Apr 25;127:110153 Authors: Laskar YB, Mazumder PB Abstract Hibiscus sabdariffa or roselle tea is popular around the globe for its antioxidant capability along with various other health benefits. Besides, it has uses in Ayurvedic and Chinese herbal medicines for the treatment of several diseases....
Wed Apr 29, 2020 14:55
Related ArticlesThe coordinate actions of calcineurin and Hog1 mediate the stress response through multiple nodes of the cell cycle network. PLoS Genet. 2020 Apr 28;16(4):e1008600 Authors: Leech CM, Flynn MJ, Arsenault HE, Ou J, Liu H, Zhu LJ, Benanti JA Abstract Upon exposure to environmental stressors, cells transiently arrest the cell cycle while they adapt and restore homeostasis. A challenge for all cells is to distinguish between stress signals...
Wed Apr 29, 2020 14:55
Related ArticlesNaringin induces endoplasmic reticulum stress-mediated apoptosis, inhibits β-catenin pathway and arrests cell cycle in cervical cancer cells. Acta Biochim Pol. 2020 Apr 28;: Authors: Chen S, Lin R, Hu X, Shi Q, Chen H Abstract Naringin is a promising anticancer bioflavonoid phytochemical, mainly extracted from citrus fruits. This study evaluates the antiproliferative effect and the cell death mechanism induced by naringin on cervical...
Wed Apr 29, 2020 14:55
Related ArticlesKnockdown of A-kinase anchor protein 4 inhibits proliferation of triple-negative breast cancer cells in vitro and in vivo. Tumour Biol. 2020 Apr;42(4):1010428320914477 Authors: Jagadish N, Devi S, Gupta N, Suri V, Suri A Abstract Triple-negative breast cancers are the most aggressive subtypes with poor prognosis due to lack of targeted cancer therapy. Recently, we reported an association of A-kinase anchor protein 4 expression with...
Wed Apr 29, 2020 14:55
Related ArticlesKIF15 promotes the evolution of gastric cancer cells through inhibition of reactive oxygen species-mediated apoptosis. J Cell Physiol. 2020 Apr 27;: Authors: Tao J, Sun G, Li Q, Zhi X, Li Z, He Z, Chen H, Zhou A, Ye J, Xu G, Guan W, Zhang W Abstract Kinesin family member 15 (KIF15) is a member of the kinesin superfamily of proteins, which promotes cell mitosis, participates in the transport of intracellular materials, and helps structural...
Wed Apr 29, 2020 13:05
Related ArticlesScreening of Long Noncoding RNAs Induced by Radiation Using Microarray. Dose Response. 2020 Apr-Jun;18(2):1559325820916304 Authors: Wang Y, Wang Q, Chen S, Hu Y, Yu C, Liu R, Wang Z Abstract DNA damage repair and G2/M arrest are the key factors regulating the survival of cancer cells exposed to radiation. Recent studies have shown that long noncoding RNAs (lncRNAs) play important roles in a variety of biological processes, including...
Wed Apr 29, 2020 13:05
Related ArticlesR-spondin2 signaling is required for oocyte-driven intercellular communication and follicular growth. Cell Death Differ. 2020 Apr 27;: Authors: De Cian MC, Gregoire EP, Le Rolle M, Lachambre S, Mondin M, Bell S, Guigon CJ, Chassot AA, Chaboissier MC Abstract R-spondin2 (RSPO2) is a member of the R-spondin family, which are secreted activators of the WNT/β-catenin (CTNNB1) signaling pathway. In the mouse postnatal ovary, WNT/CTNNB1...
Wed Apr 29, 2020 13:05
Related ArticlesElimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice. Cell Res. 2020 Apr 27;: Authors: Cai Y, Zhou H, Zhu Y, Sun Q, Ji Y, Xue A, Wang Y, Chen W, Yu X, Wang L, Chen H, Li C, Luo T, Deng H Abstract Cellular senescence, a persistent state of cell cycle arrest, accumulates in aged organisms, contributes to tissue dysfunction, and drives age-related phenotypes....
Wed Apr 29, 2020 13:05
Related ArticlesActive replication checkpoint drives genome instability in fission yeast mcm4 mutant. Mol Cell Biol. 2020 Apr 27;: Authors: Kim SM, Forsburg SL Abstract Upon replication fork arrest, the replication checkpoint kinase Cds1 is stimulated to preserve genome integrity. Robust activation of Cds1 in response to hydroxyurea prevents endonuclease Mus81 from cleaving the stalled replication fork inappropriately. However, we find that the response...
Wed Apr 29, 2020 13:05
Related Articlesp27 as a transcriptional regulator: New roles in development and cancer. Cancer Res. 2020 Apr 27;: Authors: Slingerland JM, Razavipour SF, Harikumar KB Abstract p27 binds and inhibits cyclin-CDK to arrest the cell cycle. p27 also regulates other processes including migration and development independent of its CDK inhibitory action. p27 is an atypical tumor suppressor: deletion or mutational inactivation of the gene encoding p27, CDKN1B,...
Wed Apr 29, 2020 13:05
Related ArticlesCheckpoint kinase 1 is essential for fetal and adult hematopoiesis. EMBO Rep. 2019 08;20(8):e47026 Authors: Schuler F, Afreen S, Manzl C, Häcker G, Erlacher M, Villunger A Abstract Checkpoint kinase 1 (CHK1) is critical for S-phase fidelity and preventing premature mitotic entry in the presence of DNA damage. Tumor cells have developed a strong dependence on CHK1 for survival, and hence, this kinase has developed into a promising drug...
Wed Apr 29, 2020 13:05
OBJECTIVE: The aim of this study was to explore the association between the expression of mitogen-activated protein kinase (MAPK)/extracellular regulated protein kinase (ERK) pathway and neuronal apoptosis in rats with white matter lesions (WML).MATERIALS AND METHODS: Sprague-Dawley (SD) rats were selected as the research objects. Rat models of ischemic WML were established by bilateral common carotid artery ligation. Subsequently, brain tissues were collected from rats in sham operation group and...
Wed Apr 29, 2020 12:35
OBJECTIVE: To investigate the expression of circ_0072309 in patients with ischemic stroke (IS) and in LIFR humanized mice with middle cerebral artery occlusion (MCAO). Further, we explored the underlying mechanism of circ-0072309 in IS.MATERIALS AND METHODS: The content of circ-0072309 in serum of patients with IS (n = 70) was measured by qRT-PCR, and the ROC curve was analyzed. LIFR humanized mice were used to measure the content of circ-0072309 in ischemic hemisphere by qRT-PCR and the protein...
Wed Apr 29, 2020 12:35
Related ArticlesTargeted alpha therapy using astatine (211At)-labeled phenylalanine: A preclinical study in glioma bearing mice. Oncotarget. 2020 Apr 14;11(15):1388-1398 Authors: Watabe T, Kaneda-Nakashima K, Shirakami Y, Liu Y, Ooe K, Teramoto T, Toyoshima A, Shimosegawa E, Nakano T, Kanai Y, Shinohara A, Hatazawa J Abstract Phenylalanine derivatives, which target tumors especially through L-type amino acid transporter-1 (LAT1), have elicited considerable...
Wed Apr 29, 2020 13:03
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου