Abstract The proper development and function of skin and hair is dependent on proteolytic activities. Specifically, the matriptase‐prostasin cascade is a series of proteolytic reactions in the epidermis integral to normal regulation of desquamation. An increasing amount of research describing this pathway has recently become available, and the importance of this pathway is exhibited by the association of genetic defects in this pathway with human diseases of the skin and hair. Given the relevance...
Wed Apr 29, 2020 11:30
26 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Proc Natl Acad Sci U S A"[jour] These pubmed results were generated on 2020/04/29PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Apr 29, 2020 15:12
26 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Proc Natl Acad Sci U S A"[jour] These pubmed results were generated on 2020/04/29PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Apr 29, 2020 13:15
Publication date: Available online 29 April 2020Source: Computer Speech & LanguageAuthor(s): Blaž Škrlj, Matej Martinc, Jan Kralj, Nada Lavrač, Senja Pollak
Wed Apr 29, 2020 15:08
Related ArticlesMycosis Fungoides of the True Vocal Folds: A Case Report. Ann Otol Rhinol Laryngol. 2020 Apr 27;:3489420916213 Authors: Qualliotine JR, Ahluwalia R, Tzachanis D, Sanghvi P, Weissbrod PA Abstract OBJECTIVES: To report a case of laryngeal involvement of mycosis fungoides and its symptomatic treatment with laser-assisted surgical ablation. METHODS: Case report and literature review. RESULTS: A 76-year-old woman with...
Wed Apr 29, 2020 15:04
Related ArticlesTemporal Bone Encephaloceles: Utility of Preoperative Imaging. Otolaryngol Head Neck Surg. 2020 Apr 28;:194599820918566 Authors: Worrall DM, Pai A, Garneau JC, Perez ER, Cosetti MK, Smouha EE, Wanna GB Abstract OBJECTIVE: To determine the diagnostic efficacy and clinical value of preoperative computed tomography (CT) and magnetic resonance imaging (MRI) among patients with suspected temporal bone encephaloceles (TBE). STUDY DESIGN:...
Wed Apr 29, 2020 15:03
Related ArticlesAssociation of Intracranial Hypertension With Calvarial and Skull Base Thinning. Otol Neurotol. 2019 07;40(6):e619-e626 Authors: Rabbani CC, Patel JM, Nag A, Schueth E, Saltagi MZ, Kao R, Nelson RF Abstract OBJECTIVE: Determine if patients with increased opening pressure (OP) on lumbar puncture (LP) have thinner calvaria and skull bases. STUDY DESIGN: Retrospective cohort study. SETTING: Tertiary referral center. ...
Wed Apr 29, 2020 15:03
Related ArticlesCorrection to Photoactivatable Prolyl Hydroxylase 2 Inhibitors for Stabilizing the Hypoxia-Inducible Factor with Light. J Med Chem. 2020 Apr 28;: Authors: Li Z, Su K, Jiang Z, Yu Y, You Q, Zhang X PMID: 32343575 [PubMed - as supplied by publisher]
Wed Apr 29, 2020 14:57
Publication date: Available online 28 April 2020Source: Pathology - Research and PracticeAuthor(s): Jing Zhang, Min Zhou, Xixia Zhao, Guoqing Wang, Jieqiong Li
Wed Apr 29, 2020 14:53
Related ArticlesKIF15 promotes the evolution of gastric cancer cells through inhibition of reactive oxygen species-mediated apoptosis. J Cell Physiol. 2020 Apr 27;: Authors: Tao J, Sun G, Li Q, Zhi X, Li Z, He Z, Chen H, Zhou A, Ye J, Xu G, Guan W, Zhang W Abstract Kinesin family member 15 (KIF15) is a member of the kinesin superfamily of proteins, which promotes cell mitosis, participates in the transport of intracellular materials, and helps structural...
Wed Apr 29, 2020 14:48
Related ArticlesThe roles of GRP81 as a metabolic sensor and inflammatory mediator. J Cell Physiol. 2020 Apr 28;: Authors: Hu J, Cai M, Liu Y, Liu B, Xue X, Ji R, Bian X, Lou S Abstract GPR81 (also named as HCA1) is a member of a subfamily of orphan G-protein coupled receptors (GPCRs), coupled to Gi -type G proteins. GPR81 was discovered in 2001 and identified as the only known endogenous receptor of lactate under physiological conditions in 2008, which...
Wed Apr 29, 2020 14:48
Related ArticlesA novel role of VEPH1 in regulating AoSMC phenotypic switching. J Cell Physiol. 2020 Apr 27;: Authors: Shi X, Xu C, Li Y, Wang H, Ma W, Tian Y, Yang H, Li L Abstract Abdominal aortic aneurysm (AAA) is a potentially lethal disease featured by focal dilatation in the aorta. The transition of vascular smooth muscle cells (SMCs) from a contractile/differentiated to a synthetic/dedifferentiated phenotype is considered to contribute to AAA...
Wed Apr 29, 2020 14:48
Related ArticlesA robust six-miRNA prognostic signature for head and neck squamous cell carcinoma. J Cell Physiol. 2020 Apr 28;: Authors: Zhao X, Cui L Abstract Head and neck squamous cell carcinoma (HNSCC) remains a major health problem worldwide. We aimed to identify a robust microRNA (miRNA)-based signature for predicting HNSCC prognosis. The miRNA expression profiles of HNSCC were obtained from The Cancer Genome Atlas (TCGA) database. The TCGA HNSCC...
Wed Apr 29, 2020 14:48
Abstract This study examined sensitivity of eye tracking measures to hyperphagia severity in Prader‐Willi syndrome (PWS). Gaze data were collected in 57 children with PWS, age 3–11 years, and 47 typically developing peers at two study sites during free visual exploration of complex stimulus arrays that included images of food, animals, and household objects. Analysis of the number and duration of fixations as well as gaze perseverations revealed that food items are not exceptionally salient for...
Tue Apr 28, 2020 14:58
Abstract Adults with Down syndrome (DS) represent a unique population who are in need of clinical guidelines to address their medical care. Many of these conditions are of public health importance with the potential to develop screening recommendations to improve clinical care for this population. Our workgroup previously identified and prioritized co‐occurring medical conditions in adults with DS. In this study, we again performed detailed literature searches on an additional six medical conditions...
Mon Apr 27, 2020 11:14
Related ArticlesAutophagy driven extracellular vesicles in the leukaemic microenvironment. Curr Cancer Drug Targets. 2020 Apr 28;: Authors: Horton R, Wileman T, Rushworth SA Abstract The leukaemias are a heterogenous group of blood cancers which, together, caused 310,000 deaths in 2016. Despite significant research into their biology and therapeutics leukaemia is predicted to account for an increased 470,000 deaths in 2040. Many subtypes remain without...
Wed Apr 29, 2020 14:44
Related ArticlesRetro-psoas muscle vermiform appendix: an unusual location. Surg Radiol Anat. 2020 Apr 27;: Authors: Rousan LA, Jibril MI Abstract The vermiform appendix is considered the most mobile organ in the human body. Due to its various positions in the abdomen and pelvis, it may result in confusion in diagnosis to the surgeons when it becomes inflamed. Atypical locations of the appendix have been reported previously in the literature. We...
Wed Apr 29, 2020 14:44
Related ArticlesCorrection: Transcultural mediation programme in a paediatric hospital in France: qualitative and quantitative study of participants' experience and impact on hospital costs. BMJ Open. 2020 Apr 26;10(4):e032498corr1 Authors: PMID: 32341048 [PubMed - in process]
Wed Apr 29, 2020 14:44
Related ArticlesText messages for primary prevention of cardiovascular disease: the TextMe2 randomised controlled trial protocol. BMJ Open. 2020 Apr 26;10(4):e036767 Authors: Klimis H, Thiagalingam A, Chow CK Abstract INTRODUCTION: Mobile health may be an effective means of delivering customised individually directed health promotion interventions for cardiovascular disease (CVD) primary prevention. The aim of this study is to evaluate the effectiveness...
Wed Apr 29, 2020 14:44
Related ArticlesProtocol for a systematic review of health promotion interventions for African Americans delivered in US barbershops and hair salons. BMJ Open. 2020 Apr 26;10(4):e035940 Authors: Palmer K, Rivers P, Melton F, McClelland J, Hatcher J, Marrero DG, Thomson C, Garcia DO Abstract INTRODUCTION: African American adults are disproportionately burdened by chronic diseases, particularly at younger ages. Developing culturally appropriate interventions...
Wed Apr 29, 2020 14:44
Related ArticlesCoronary artery disease prediction in women and men using chest pain characteristics and risk factors: an observational study in outpatient clinics. BMJ Open. 2020 Apr 26;10(4):e035928 Authors: Groepenhoff F, Eikendal ALM, Onland-Moret NC, Bots SH, Menken R, Tulevski II, Somsen AG, Hofstra L, den Ruijter HM Abstract OBJECTIVES: To assess the diagnostic value of non-acute chest pain characteristics for coronary artery disease in women...
Wed Apr 29, 2020 14:44
Related Articles(Cost-)effectiveness of lower extremity nerve decompression surgery in subjects with diabetes: the DeCompression (DECO) trial-study protocol for a randomised controlled trial. BMJ Open. 2020 Apr 26;10(4):e035644 Authors: Rinkel WD, Fakkel TM, Castro Cabezas M, Birnie E, Coert JH Abstract INTRODUCTION: The peripheral nerves of patients with diabetes are often pathologically swollen, which results in entrapment at places of anatomical narrowing....
Wed Apr 29, 2020 14:44
Related ArticlesPrevalence of mental health conditions, sensory impairments and physical disability in people with co-occurring intellectual disabilities and autism compared with other people: a cross-sectional total population study in Scotland. BMJ Open. 2020 Apr 26;10(4):e035280 Authors: Dunn K, Rydzewska E, Fleming M, Cooper SA Abstract OBJECTIVES: To investigate prevalence of mental health conditions, sensory impairments and physical disability...
Wed Apr 29, 2020 14:44
Related ArticlesHuman resources and curricula content for early child development implementation: multicountry mixed methods evaluation. BMJ Open. 2020 Apr 26;10(4):e032134 Authors: Kohli-Lynch M, Ponce Hardy V, Bernal Salazar R, Bhopal SS, Brentani A, Cavallera V, Goh E, Hamadani JD, Hughes R, Manji K, Milner KM, Radner J, Sharma S, Silver KL, Lawn JE, Tann CJ Abstract OBJECTIVE: The WHO recommends responsive caregiving and early learning (RCEL) interventions...
Wed Apr 29, 2020 14:44
Related ArticlesPaediatricians' attitudes and beliefs towards transgender people: a cross-sectional survey in Israel. BMJ Open. 2020 Apr 26;10(4):e031569 Authors: Landau N, Hamiel U, Tokatly Latzer I, Mauda E, Levek N, Tripto-Shkolnik L, Pinhas-Hamiel O Abstract OBJECTIVE: The number of transgender and gender non-conforming children is on the rise. For these children, the timing of medical intervention is crucial, yet transgender children report poorer...
Wed Apr 29, 2020 14:44
Related ArticlesHIV and opiates dysregulate K+-Cl- cotransporter 2 (KCC2) to cause GABAergic dysfunction in primary human neurons and Tat-transgenic mice. Neurobiol Dis. 2020 Apr 25;:104878 Authors: Barbour AJ, Hauser KF, McQuiston AR, Knapp PE Abstract Approximately half of people infected with HIV (PWH) exhibit HIV-associated neuropathology (neuroHIV), even when receiving combined antiretroviral therapy. Opiate use is widespread in PWH and exacerbates...
Wed Apr 29, 2020 14:42
Related ArticlesA Case of Scabies Presenting as Chronic Urticaria. Mil Med. 2020 Apr 28;: Authors: Muller I, Brinker A Abstract Scabies outbreaks are relatively common worldwide, particularly in communal living settings such as military barracks. The infestation is caused by the parasite Sarcoptes Scabiei and is easily treated once properly diagnosed. Classic symptoms include pruritus around the waist, wrists, and ankles.1 On physical examination, linear...
Wed Apr 29, 2020 14:42
Publication date: Available online 29 April 2020Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Jake D. Rosenblum, Stacy Nassau, Luz Fonacier, Stephanie L. Mawhirt
Wed Apr 29, 2020 14:41
Publication date: Available online 29 April 2020Source: TalantaAuthor(s): Abolghasem Jouyban, Elaheh Rahimpour
Wed Apr 29, 2020 14:39
Objective: The aim of this study was to determine the utility of dynamic-ventilatory digital radiography (DR) for pulmonary function assessment in patients with airflow limitation. Methods: One hundred and eighteen patients with airflow limitation (72 patients with lung cancer before surgery, 35 patients with chronic obstructive pulmonary disease [COPD], 6 patients with asthma, and 5 patients with asthma-COPD overlap syndrome) were assessed with dynamic-ventilatory DR. The patients were instructed...
Wed Apr 29, 2020 12:39
Related ArticlesEpileptic seizures triggered by eating in dogs. J Vet Intern Med. 2020 Apr 28;: Authors: Brocal J, Lowrie M, Wamsley G, Cauduro A, Mandigers P, Gutierrez-Quintana R, Stalin C Abstract BACKGROUND: Seizures triggered by eating (STE) behavior are very rare in humans and have not been documented previously in dogs. OBJECTIVES: To document the occurrence of STE in dogs and describe their clinical features. ANIMALS: Ten client-owned...
Wed Apr 29, 2020 14:24
Related ArticlesPrevalence and treatment of neurological and psychiatric disorders among tertiary hospitals in Pakistan; findings and implications. Hosp Pract (1995). 2020 Apr 28;: Authors: Khan TA, Hussain S, Ikram A, Mahmood S, Riaz H, Jamil A, Amin A, Haider YG, Sandhu M, Mushtaq A, Barbui C, Johnson CF, Godman B Abstract Introduction: Mental health and neurological disorders are prevalent in Pakistan. However, there are considerable concerns with...
Wed Apr 29, 2020 14:24
Related ArticlesAntiepileptic drugs as prophylaxis for postcraniotomy seizures. Cochrane Database Syst Rev. 2020 Apr 28;4:CD007286 Authors: Greenhalgh J, Weston J, Dundar Y, Nevitt SJ, Marson AG Abstract BACKGROUND: This is an updated version of the Cochrane Review previously published in 2018. The incidence of seizures following supratentorial craniotomy for non-traumatic pathology has been estimated to be between 15% to 20%; however, the risk of experiencing...
Wed Apr 29, 2020 14:24
Related ArticlesCaspase-1 inhibition prevents neuronal death by targeting the canonical inflammasome pathway of pyroptosis in a murine model of cerebral ischemia. CNS Neurosci Ther. 2020 Apr 28;: Authors: Li J, Hao JH, Yao D, Li R, Li XF, Yu ZY, Luo X, Liu XH, Wang MH, Wang W Abstract AIMS: The involvement of pyroptosis in ischemic stroke remains to be established. Therefore, we used the specific pyroptosis inhibitor Vx765 as an experimental intervention...
Wed Apr 29, 2020 14:24
Related ArticlesNovel variant in CHRNA4 with benign childhood epilepsy with centrotemporal spikes and contribution to precise medicine. Mol Genet Genomic Med. 2020 Apr 28;:e1264 Authors: Neng X, Xiao M, Yuanlu C, Qinyan L, Li S, Zhanyi S Abstract BACKGROUND: Benign childhood epilepsy with centrotemporal spikes (BECTS) or benign rolandic epilepsy is the most common epileptic syndrome in school-age children. Genetics is an important factor in BECTS pathogenesis,...
Wed Apr 29, 2020 14:24
Related ArticlesCadmium activates AMPA and NMDA receptors with M3 helix cysteine substitutions. J Gen Physiol. 2020 Jul 06;152(7): Authors: Wilding TJ, Huettner JE Abstract AMPA and NMDA receptors are ligand-gated ion channels that depolarize postsynaptic neurons when activated by the neurotransmitter L-glutamate. Changes in the distribution and activity of these receptors underlie learning and memory, but excessive change is associated with an array...
Wed Apr 29, 2020 14:24
Related ArticlesThe effect of pretreatment with hydroalcoholic extract of Alpinia officinarum rhizome on seizure severity and memory impairment in pentylenetetrazol-induced kindling model of seizure in rat. AIMS Neurosci. 2019;6(3):128-145 Authors: Solati K, Rabiei Z, Asgharzade S, Amini-Khoei H, Hassanpour A, Abbasiyan Z, Anjomshoa M, Rafieian-Kopaei M Abstract The aim of present study is to investigate pretreatment with hydroalcoholic extract of Alpinia...
Wed Apr 29, 2020 14:24
Related ArticlesThe Role of Quantitative EEG in the Diagnosis of Neuropsychiatric Disorders. J Med Life. 2020 Jan-Mar;13(1):8-15 Authors: Livint Popa L, Dragos H, Pantelemon C, Verisezan Rosu O, Strilciuc S Abstract Quantitative electroencephalography (QEEG) is a modern type of electroencephalography (EEG) analysis that involves recording digital EEG signals which are processed, transformed, and analyzed using complex mathematical algorithms. QEEG has...
Wed Apr 29, 2020 14:24
Related ArticlesSeizures during treatment of childhood acute lymphoblastic leukemia: A population-based cohort study. Eur J Paediatr Neurol. 2020 Apr 18;: Authors: Anastasopoulou S, Heyman M, Eriksson MA, Niinimäki R, Taskinen M, Mikkel S, Vaitkeviciene GE, Johannsdottir IM, Myrberg IH, Jonsson OG, Als-Nielsen B, Schmiegelow K, Banerjee J, Ranta S, Harila-Saari A Abstract BACKGROUND: Seizures are common in children with acute lymphoblastic leukemia (ALL)....
Wed Apr 29, 2020 14:24
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