Managing decisions of pancreatic neuroendocrine tumors (pNETs) can be challenging because of different clinical presentations and prognosis. A 31-year-old woman with multiple endocrine neoplasia type 1, including a suspicious pNET, was assessed with 68Ga-DOTATOC and 18F-FDG PET. A high 68Ga-DOTATOC uptake was visualized in the entire pNET, whereas a high 18F-FDG PET uptake was present only in the upper part of the tumor. After surgery, pathology confirmed the pNET with a double component: an upper...
Tue Apr 28, 2020 03:00
The chief medical officer (CMO) is a key member of the administration of most large health care systems. The CMO helps with communication between the medical staff and the nonphysician administrators. The CMO typically plays an important role in utilization review, ensuring compliance with laws and regulations, peer review, credentialing, and privileging. One of the most important roles of the CMO has been to improve quality and safety while keeping costs under control, although now many institutions...
Tue Apr 28, 2020 03:00
FuMeGA Criteria for Visual Assessment of Postoperative 18F-Fluorocholine PET in Patients With Glioma
Postoperative assessment is crucial in the imaging follow-up and prognosis in patients with glioma. Whereas grade of resection is defined attending to the gadolinium enhancement in early postoperative MRI, no metabolical criteria exist for postoperative PET interpretation. Based on our prospective and multicenter FuMeGA (Functional and Metabolic Glioma Analysis) ongoing study, we propose criteria for the visual interpretation of 18F-fluorocholine PET scans in patients undergoing brain tumor resection....
Tue Apr 28, 2020 03:00
The field of telehealth is growing thanks to the steady growth in supportive technology and the need for remote monitoring, assessment, diagnosis, and testing. Voice is unique to every individual due to people’s anatomical differences, which makes for a powerful tool when working remotely. Vocalis Health is a company that uses machine learning and artificial intelligence to identify biomarkers in voice recordings. The company’s technology has been successfully used to identify mortality...
Wed Apr 29, 2020 21:59
Because of the common expectation that ventilators would be in dire shortage during the ongoing COVID-19 pandemic, many teams around the world have developed simple ventilators that utilize bag valve masks (AmbuBags) to pump air in and out of the lungs. Most of these do not provide nuanced control of ventilation settings such as the inspiration and expiration ratio and pressure in the lungs. A Georgia Tech team has just unveiled a prototype, portable, emergency ventilator that provides clinicians...
Wed Apr 29, 2020 19:02
Researchers at the University of Western Australia have demonstrated that facial features captured from 3D photographs may be useful as a screening tool for sleep apnea. 400 individuals participated in the study, and the researchers found that they could predict which patients would have sleep apnea with up to 91% accuracy. 300 individuals with sleep apnea and 100 individuals without sleep apnea were enrolled in the study, which involved overnight sleep studies and 3D photography with...
Wed Apr 29, 2020 16:57
Researchers at the Korea Basic Science Institute, Korea Research Institute of Chemical Technology, and collaborators have published an article on the development of graphene-based test for SARS-CoV-2, the virus causing COVID-19, from nasopharyngeal swabs. They have determined it can detect SARS-CoV-2 in clinical samples at a concentration of 242 copies per mL. and greater, a significant achievement. Current diagnostic tests for COVID-19 utilize RT-PCR, amplifying the SARS-CoV-2 RNA from patient...
Wed Apr 29, 2020 16:46
Abstract Background Wolfram syndrome (WFS) is a rare, monogenic neurodegenerative syndrome characterised by insulin requiring non-autoimmune diabetes mellitus (DM) and optic atrophy which are usually the earliest and commonest manifestations. However, there are other features which are under-recognized, adding to morbidity and premature mortality in these patients. Methods...
Wed Apr 29, 2020 03:00
AbstractCholecystitis is a rare sequela of colonoscopy, the relationship between which has not yet been defined. This case study reviews a rural elderly patient who developed right upper quadrant pain following routine colonoscopy. He developed emphysematous cholecystitis, which required laparoscopy with conversion to open via Kocher’s incision and underwent a subtotal cholecystectomy due to the severity of necrosis and inflammation. He had an uncomplicated recovery. Colonoscopy is an important diagnostic...
Wed Apr 29, 2020 03:00
AbstractThymolipoma is a rare benign slow-growing encapsulated tumor of anterior mediastinum that accounts for 2–9% of all thymic neoplasms. About 30–50% of them are asymptomatic and found incidentally. Less than 200 cases have been published in the world literature so far. Here we report a case of thymolipoma of an adult female presented with progressive dyspnea, chest tightness and non-productive chough for 2-month duration. All blood investigations were normal. Radiological examinations suggested...
Wed Apr 29, 2020 03:00
AbstractPrimary infection of the sternomanubrial joint (SMJ) is extremely rare. We present four consecutive cases who were all treated with SMJ resection (partial sternectomy), bilateral partial 2nd rib resection and immediate placement of temporary wound vacuum therapy followed by pectoralis major muscle flap closure. Average patient age was 35.5 years with male predominance (75%). All patients had intravenous drug use as underlying risk factor along with concomitant viral infections Hep C (75%)...
Wed Apr 29, 2020 03:00
AbstractAutologous chondrocyte implantation (ACI) is an important operative option when repairing cartilage defects of the knee. This report introduces a new product development with one-stage ACI using a Reveille Cartilage Processor (Reveille CP) as well as the assessment of MRI and clinical results at a 1-year follow-up. The report compared cases between a 42-year-old female who underwent ACI surgery using Reveille CP and a 51-year old female who received treatment with two-stage ACI of tissue-engineered...
Wed Apr 29, 2020 03:00
Publication date: Available online 28 April 2020Source: Allergologia et ImmunopathologiaAuthor(s): M.H. Celiksoy, C. Dogan, B. Erturk, E. Keskin, B.S. Ada
Wed Apr 29, 2020 21:28
Publication date: Available online 28 April 2020Source: Allergologia et ImmunopathologiaAuthor(s): Xiaobo Xuan, Ziyan Sun, Chenhuan Yu, Jian Chen, Mei Chen, Qili Wang, Lan Li
Wed Apr 29, 2020 21:28
The goal of this protocol is to quantify binding of the eukaryotic pathogen human norovirus to bacteria. After performing an initial virus-bacterium attachment assay, flow cytometry is used to detect virally-bound bacteria within the population.
Wed Apr 29, 2020 21:25
Presented here is a protocol to evaluate the inhibition efficacy of chemical compounds against in vitro intracellular growth of Toxoplasma gondii using a luciferase-based growth assay. The technique is used to confirm inhibition specificity by genetic deletion of the corresponding target gene. The inhibition of LHVS against TgCPL protease is evaluated as an example.
Wed Apr 29, 2020 21:00
We report the application of quantitative chromosome conformation capture followed by high-throughput sequencing in embryoid bodies generated from embryonic stem cells. This technique allows to identify and quantitate the contacts between putative enhancers and promoter regions of a given gene during embryonic stem cell differentiation.
Wed Apr 29, 2020 20:25
Publication date: Available online 28 April 2020Source: Behavioural Brain ResearchAuthor(s): Marika Berchicci, Yuri Russo, Valentina Bianco, Federico Quinzi, Lorenzo Rum, Andrea Macaluso, Giorgia Committeri, Giuseppe Vannozzi, Francesco Di Russo
Wed Apr 29, 2020 21:05
Publication date: Available online 28 April 2020Source: Behavioural Brain ResearchAuthor(s): Xiang Li, Xianan Sun, Jing Sun, Yi Zu, Shulei Zhao, Xiao Sun, Lu Li, Xinjing Zhang, Wei Wang, Yuezhu Liang, Wenyao Wang, Xuankai Liang, Chi Sun, Xue Guan, Man Tang
Wed Apr 29, 2020 21:05
Publication date: Available online 29 April 2020Source: Allergology InternationalAuthor(s): Motohiro Ebisawa, Komei Ito, Takao Fujisawa, Motohiro Ebisawa, Komei Ito, Takao Fujisawa, Yukoh Aihara, Setsuko Ito, Takanori Imai, Yusei Ohshima, Yukihiro Ohya, Hideo Kaneko, Yasuto Kondo, Naoki Shimojo, Mizuho Nagao, Yasunori Ito, Yuzaburo Inoue, Ikuo Okafuji, Sakura Sato, Yoichi Nakajima
Wed Apr 29, 2020 20:31
Abstract Purpose This consensus statement from the Breast Cancer Working Group of the German Society for Radiation Oncology (DEGRO) aims to define practical guidelines for accelerated partial-breast irradiation (APBI). Methods Recent recommendations for relevant aspects of APBI were summarized and a panel of experts reviewed all the relevant literature....
Wed Apr 29, 2020 03:00
Publication date: May–June 2020Source: Brachytherapy, Volume 19, Issue 3Author(s):
Wed Apr 29, 2020 19:49
Publication date: May–June 2020Source: Brachytherapy, Volume 19, Issue 3Author(s): Ashwini Budrukkar, Tejshri Telkhade, Tabassum Wadasadawala, Tanuja Shet, Ritu Raj Upreti, Rakesh Jalali, Rajendra Badwe, Sudeep Gupta, Rajiv Sarin
Wed Apr 29, 2020 19:49
Publication date: May–June 2020Source: Brachytherapy, Volume 19, Issue 3Author(s):
Wed Apr 29, 2020 19:49
Publication date: May–June 2020Source: Brachytherapy, Volume 19, Issue 3Author(s):
Wed Apr 29, 2020 19:49
Publication date: Available online 29 April 2020Source: BrachytherapyAuthor(s): Daniel G. Petereit
Wed Apr 29, 2020 19:49
Food has always been a way my family has defined itself. When my sons reminisce about my parents’ farm, they might mention Grandma’s apple pie served New England style with cheese and Grandpa’s Southern breakfast of sausage, grits, and redeye gravy, eaten before watching Cisco Kid on their 1960s-era black-and-white TV. My daughter Kharran loved exploring different cuisines. “In a week,” her daughter Madrid told me, “Mom could cook the family dinner every night featuring a dish from a different...
Wed Apr 29, 2020 19:30
This piece is part of the SEAA series “An Anthropology of Ethics in East Asia.” The articles highlight different aspects of moral values and ethical practices in a range of Asian regions. They examine how individuals cope with societal changes such as environmental crises, nationalism, economic development, and mobility through lens of everyday ethics. “I chose to not worry about radiation anymore, for as long as I stay living here; to live normally again for my children and my family,” said Kazumi,...
Wed Apr 29, 2020 16:30
Publication date: Available online 28 April 2020Source: Revue des Maladies RespiratoiresAuthor(s): P. Castan, G. Maigne, J. Boutemy, N. Martin Silva, H. De Boysson, A. Aouba, A. Audemard-Verger
Wed Apr 29, 2020 19:31
Publication date: Available online 28 April 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Pretty Sara Idiculla, Raghav Govindarajan
Wed Apr 29, 2020 19:19
Publication date: Available online 28 April 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Arash Ghaffari-Rafi, Rachel Gorenflo, Huanli Hu, Jason Viereck, Kore Liow
Wed Apr 29, 2020 19:19
Radiothérapie avec modulation d’intensité préopératoire des cancers rectaux : intérêt et application
Publication date: Available online 28 April 2020Source: Cancer/RadiothérapieAuthor(s): V. Randrian, J. Biau, C. Benoît, D. Pezet, M. Lapeyre, J. Moreau
Wed Apr 29, 2020 19:18
Publication date: Available online 28 April 2020Source: Cancer/RadiothérapieAuthor(s): L.S. Fournier, A.-S. Bats, C. Durdux
Wed Apr 29, 2020 19:18
Publication date: April 2020Source: Cancer/Radiothérapie, Volume 24, Issue 2Author(s):
Wed Apr 29, 2020 19:18
Publication date: April 2020Source: Cancer/Radiothérapie, Volume 24, Issue 2Author(s):
Wed Apr 29, 2020 19:18
Publication date: Available online 28 April 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Liang Hu, Jing-Sheng Zhao, Cong Xing, Xiao-Ling Xue, Xiao-Li Sun, Rong-Fang Dang, Wen-Zhi Chen, Zhi-Biao Wang, Jin-Yun Chen
Wed Apr 29, 2020 19:11
Publication date: Available online 28 April 2020Source: Journal of ProteomicsAuthor(s): Cabiddu Gianluigi, Maes Pauline, Hyvrier Franck, Olianas Alessandra, Manconi Barbara, Brignot Hélène, Canon Francis, Cabras Tiziana, Morzel Martine
Wed Apr 29, 2020 19:09
Publication date: Available online 29 April 2020Source: Archives of Oral BiologyAuthor(s): Caroline Sousa Ribeiro Adeodato, Gutemberg Gomes Alves, Ana Maria Nunes Botelho, Isleine Portal Caldas, Fabiano Palmeira Gonçalves, Luis Felipe Ribeiro Pinto, Sheila Coelho Soares Pinto, Marina Chianello Nicolau Fagundes, Daniele Masterson, Pantaleo Scelza, Miriam Fátima Zaccaro Scelza
Wed Apr 29, 2020 18:55
Abstract Salivary duct carcinoma (SDC) commonly expresses androgen receptor (AR) and HER2, giving rise to treatment implications. SDC may also express programmed-death-ligand-1 (PD-L1), a predictive marker of response to checkpoint inhibitors. PD-L1 can be associated with genomic instability and high density of tumor infiltrating lymphocytes (TILs). Evaluation of HER2 immunohistochemistry (IHC) in SDC is not standardized, and relationships between ERBB2 copy numbers, PD-L1 expression...
Wed Apr 29, 2020 03:00
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