We present a case of inflammatory abdominal arterial aneurysms, which demonstrates the potential usefulness of PET/CT with 18F-FDG in long-term monitoring of this disease, but also demonstrates potential pitfalls in abdominal arterial aneurysm imaging with PET/CT. Imaging may be challenged as the initial presentation prior to therapy may mimic an infected aneurysm. Follow-up images may be mistaken for vascular graft infection or persistent disease. Received for publication September 17, 2019;...
An 80-year-old man developed high-risk prostate cancer after 7 years of active surveillance. For staging and treatment planning, a 68Ga-PSMA PET/MRI was performed. Besides the PSMA-positive primary tumor and a solitary bone metastasis in the fifth thoracic vertebral body, an intensive intrahepatic PSMA expression (SUVmax, 16.3) was suspicious for a liver metastasis. The results of a previously performed contrast-enhanced CT, a consecutively performed contrast-enhanced ultrasound, and a follow-up...
Yolk sac tumor is a rare and highly malignant germ cell tumor. We report a case of yolk sac tumor primarily in the pancreas in a 32-year-old man. He presented with pancreatitis at presentation with significantly increased serum alpha-fetoprotein (AFP). 18F-FDG PET/CT revealed diffuse enlargement of the pancreas in the neck, body, and tail portion with homogeneously increased FDG uptake, similar to the change of pancreatitis. The lesion progressively developed to a huge pancreatic mass in the follow-up...
A 51-year-old man with 30-year neurofibromatosis and 2-month elevated prostate-specific antigen and back pain underwent a 68Ga–prostate-specific membrane antigen (PSMA) PET/CT scan for possible prostate cancer. Prostate-specific membrane antigen PET/CT imaging showed no abnormal uptake of the prostate. However, in addition to PSMA uptake in his left lung, thorax, and right ilium, which was confirmed being a lung squamous cell carcinoma by a lung biopsy, widespread uptake was also observed in his...
Neurological symptoms and gastrointestinal symptoms were rare at onset in COVID-19. Here we report a 37-year-old man with vertigo, fever, and diarrhea symptoms as the first manifestation. 18F-FDG PET/CT spotted multiple ground glass opacity (GGO) lesions in the lungs, with increased tracer uptake in both lung GGOs and the whole colon. Serial CT examinations showed the emersion and dissipation of lung GGOs. We illustrate the symptoms initiation, the laboratory test results, the imaging examination,...
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It is estimated that half of the adult population older than 60 years snores. This article discusses the many aspects of snoring, including impacts on bed partners, the individual who snores, and when and how to appropriately evaluate, diagnose, and treat the perpetrator. The goal is for clinicians to expand their knowledge regarding diagnosis and treatment of the phenomenon of snoring.It is estimated that half of the adult population over the age of 60 years of age snores. This chapter discusses...
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Allergen immunotherapy (AIT) is the only treatment option available for allergic patients with disease-modifying intention. Both efficacy and safety has been demonstrated for multiple trials in children, adole...
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A residual bone defect at the distal aspect of the adjacent second molar may occur after total removal of the lower third molar. Lower third molar coronectomy has been proved to be a safe alternative to total removal, but the extent of bone regeneration at the adjacent tooth after coronectomy is not well reported. The aim of this prospective study was to investigate the long-term bone regeneration at the distal aspect of the adjacent second molar after lower third molar coronectomy. Preoperative...
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To the Editor: Aerosols and droplets generated during speech have been implicated in the person-to-person transmission of viruses, and there is current interest in understanding the mechanisms responsible for the spread of Covid-19 by these means. The act of speaking generates oral fluid droplets…
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Publication date: Available online 23 April 2020Source: Reports of Practical Oncology & RadiotherapyAuthor(s): Shearwood McClelland, Tim Lautenschlaeger, Yong Zang, Nasser H. Hanna, Kevin Shiue, Aaron P. Kamer, Namita Agrawal, Susannah G. Ellsworth, Ryan M. Rhome, Gordon A. Watson
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COVID-19 pandemics is a challenge for public health and infectious diseases clinicians, especially for the therapeutical approach that is not yet adequately defined. Amid this situation, investigational agents...
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Abstract Objectives The aim of the present study was to assess macroscopically the time-related dimensional pattern of excisional palatal mucoperiosteal wound closure in rats, concomitantly with microscopic analysis of the density of inflammatory infiltrate and myofibroblasts. Materials and methods Excisional palatal wounds, 4.2 mm in diameter, were made...
Abstract Objectives To compare the pulp volume of individuals with altered and normal systemic blood pressure (BP) in order to verify if high BP promotes dimensional modifications in the pulp space. Materials and methods Cone beam computed tomography scans of 91 patients (49 females and 42 males, mean age 31.7 ± 6.38 years) who had a healthy maxillary canine...
Abstract Objectives This study determined the quantity of periodontopathic bacteria in saliva, subgingival plaque, and placenta on the threatened preterm labor (TPL) and preterm low birth weight (PLBW) subjects in order to identify specific periodontal pathogens with high association to adverse pregnancy outcomes. Methods We used real-time PCR with TaqMan...
Abstract Objective This study was aimed to delineate the prevalence, clinical, and 3-dimentional radiographic characteristics of adult supernumerary teeth (ST found) in a Chinese non-syndromic, dental population. Materials and methods Medical records and cone beam computed tomography (CBCT) images were utilized to identify adult patients with ST in a tertiary...
Abstract Objective To verify the photobiomodulation effect on angiogenic proteins produced and released by dental human pulpal fibroblasts (HPFs). Material and methods HPFs were irradiated with 660-nm low-level laser at fluences of 2.5 J/cm2 and 3.7 J/cm2. The control group was not irradiated. MTT, crystal violet, and ELISA assays respectively verified viability,...
Abstract Objectives The aim of this study was to evaluate the stress distribution on different thicknesses of mineral trioxide aggregate (MTA) placed on various widths of pulp perforations during the condensation of the composite resin material. Materials and methods The mandibular molar tooth was modeled by COSMOSWorks program (SolidWorks, Waltham, MA)....
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Evaluation of Mismatch Negativity as a Biomarker for Language Impairment in Autism Spectrum Disorder
Publication date: Available online 24 April 2020Source: Journal of Communication DisordersAuthor(s): Heather L. Green, Lauren Shuffrey, Lisa Levinson, Guannan Shen, Trey Avery, Melissa Randazzo Wagner, Dayna Moya Sepulveda, Paula Garcia, Chaille Maddox, Felicidad Garcia, Sommer Hassan, Karen Froud
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ObjectivesTo examine the impact of workplace injury on opioid dependence, abuse and overdose (opioid-related morbidity) and if severity of injury increases the hazard of these health effects.MethodsWe used MarketScan databases to follow injured and propensity score matched non-injured workers, both without prior opioid-related diagnoses. Using a Cox proportional hazard model, we examined the impact of workplace injury on opioid-related morbidity.ResultsThe hazard of opioid-related morbidity for injured...
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I stand in the parking lot of our emergency department and watch three men on horseback trot up the shoulder of the highway. They wear bandanas over their faces, a traditional accessory here in northwest New Mexico, where spring is wind-and-dust season. Normally, this spot is where we peek out of…
Fri Apr 24, 2020 03:00
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused clusters of severe respiratory illness in Wuhan, China, in late 2019. By January 2020, the virus had been isolated and sequenced, which revealed close relationships to coronaviruses such as SARS-CoV-1 and MERS-CoV. As of March 31,…
Tue Apr 14, 2020 03:00
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Abstract Mutations can occur throughout the virus genome and may be beneficial, neutral or deleterious. We are interested in mutations that yield a C next to a G, producing CpG sites. CpG sites are rare in eukaryotic and viral genomes. For the eukaryotes, it is thought that CpG sites are rare because they are prone to mutation when methylated. In viruses, we know less about why CpG sites are rare. A previous study in HIV suggested that CpG-creating transition mutations are more...
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Publication date: Available online 23 April 2020Source: Medical Image AnalysisAuthor(s): Biao Jie, Mingxia Liu, Chunfeng Lian, Feng Shi, Dinggang Shen
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Abstract Arm swing movement is coordinated with movement of the legs during walking, where the frequency of coordination depends on walking speed. At typical speeds, arm and leg movements, respectively, are frequency locked in a 1:1 ratio but at slow speeds this changes to a 2:1 ratio. It is unknown if the changes in interlimb ratio that accompany slow walking speeds alters regulation of somatosensory feedback. To probe the neural interactions between the arms and legs, somatosensory...
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Publication date: Available online 23 April 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Jens Kleffmann, Roman Pahl, Andreas Ferbert, Christian Roth
Publication date: Available online 23 April 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Mitchell P Wilson, Andrew S Jack
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Abstract Because the human brain is considerably larger than those of other primates, it is not surprising that its energy requirements would far exceed that of any of the species within the order. Recently, the development of stem cell technologies and single‐cell transcriptomics provides novel ways to address the question of what specific genomic changes underlie the human brain's unique phenotype. In this review, we consider what is currently known about human brain metabolism using a variety...
Fri Apr 24, 2020 17:46
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Fri Apr 24, 2020 16:09
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Publication date: Available online 24 April 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Jessica Lo, Leighton Chan, Spencer Flynn
Publication date: Available online 23 April 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Flora M. Hammond, Mark A. Hirsch, Christine S. Davis, Julia Nelson Snow, Martha Kropf, Jason Karlawish
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Correlation of Proposed Surgical Volume Standards for Complex Cancer Surgery with Hospital Mortality
Publication date: Available online 23 April 2020Source: Journal of the American College of SurgeonsAuthor(s): Nabil Wasif, David A. Etzioni, Elizabeth Habermann, Amit Mathur, Yu-Hui Chang
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Abstract Sepsis is a lethal syndrome with multiple organ failure caused by an inappropriate host response to infection. Cardiac dysfunction is one of the important complications of sepsis, termed sepsis-induced myocardial dysfunction (SIMD), which is characterized by systolic and diastolic dysfunction of both sides of the heart. Mechanisms that contribute to SIMD include an excessive inflammatory response, altered circulatory, microvascular status, nitric oxide (NO) synthesis...
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Publication date: Available online 24 April 2020Source: Journal of VoiceAuthor(s): Sujitha P S, Gopi Kishore Pebbili
Publication date: Available online 24 April 2020Source: Journal of VoiceAuthor(s): Young Ae Kang, Jae Won Chang, Ho-Ryun Won, Bon Seok Koo
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Weight-based vancomycin loading strategy may not improve achievement of optimal vancomycin concentration in patients with preserved renal function. J Chemother. 2020 Apr 23;:1-6 Authors: Kim SH, Kang CI, Lee SH, Choi JS, Huh K, Cho SY, Chung DR, Park HJ, Lee SY, Kim YJ, Peck KR Abstract We performed a retrospective study to evaluate clinical effectiveness of vancomycin loading strategy and factors associated with achieving optimal Cmin. Patients administered...
Five-year surveillance and correlation of antibiotic consumption and resistance of Gram-negative bacteria at an intensive care unit in Serbia. J Chemother. 2020 Apr 23;:1-10 Authors: Popović R, Tomić Z, Tomas A, Anđelić N, Vicković S, Jovanović G, Bukumirić D, Horvat O, Sabo A Abstract A surveillance study was performed in an intensive care unit in the largest tertiary health care center in Vojvodina, Serbia from 2014 to 2018. Antibiotic prescription...
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Publication date: Available online 23 April 2020Source: Journal of ProteomicsAuthor(s): Robert Starke, Kaitlyn Oliphant, Nico Jehmlich, Stephanie Serena Schäpe, Timo Sachsenberg, Oliver Kohlbacher, Emma Allen-Vercoe, Martin von Bergen
Publication date: Available online 23 April 2020Source: Journal of ProteomicsAuthor(s): E. Ferlizza, G. Isani, F. Dondi, G. Andreani, K. Vasylyeva, E. Bellei, A.M. Almeida, M. Matzapetakis
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