Medicina, Vol. 56, Pages 192: The Role of VEGFA, COX2, HUR and CUGBP2 in Predicting the Response to Neoadjuvant Therapy in Rectal Cancer Patients Medicina doi: 10.3390/medicina56040192 Authors: Pauzas Gyvyte Latkauskas Kairevice Lizdenis Svagzdys Birgiolaite Kuliaviene Kupcinskas Tamelis Background and objectives: The effectiveness of neoadjuvant therapy, which is commonly used for stage II-III rectal cancer (RC) treatment, is limited. Genes associated...
Wed Apr 22, 2020 03:00
Medicines, Vol. 7, Pages 22: A Double-Blind Randomized Placebo-Controlled Study Assessing the Safety, Tolerability and Efficacy of a Herbal Medicine Containing Pycnogenol Combined with Papain and Aloe vera in the Prevention and Management of Pre-Diabetes Medicines doi: 10.3390/medicines7040022 Authors: Luis Vitetta Belinda Butcher Serena Dal Forno Gemma Vitetta Tessa Nikov Sean Hall Elizabeth Steels Background: Herbal medicines present attractive options to patients...
Wed Apr 22, 2020 03:00
Medicines, Vol. 7, Pages 21: Limited Utility of Serology and Heterophile Test in the Early Diagnosis of Epstein–Barr Virus Mononucleosis in a Child after Renal Transplantation Medicines doi: 10.3390/medicines7040021 Authors: Alexandra Byrne Rachel Bush Felicia Johns Kiran Upadhyay Background: Epstein–Barr virus (EBV) infection is associated with significant morbidity and mortality in renal transplant (RT) recipients. The spectrum of illness ranges from infectious mononucleosis...
Wed Apr 22, 2020 03:00
Membranes, Vol. 10, Pages 78: Optimization of Air Backwash Frequency during the Ultrafiltration of Seawater Membranes doi: 10.3390/membranes10040078 Authors: Clemence Cordier Tarik Eljaddi Nadjim Ibouroihim Christophe Stavrakakis Patrick Sauvade Franz Coelho Philippe Moulin The main objective of this paper is to study the effect of new air backwash on dead-end ultrafiltration of seawater with a pilot at semi-industrial scale (20 m3/day). To control membrane fouling,...
Wed Apr 22, 2020 03:00
Metabolites, Vol. 10, Pages 162: A Data Set of 255,000 Randomly Selected and Manually Classified Extracted Ion Chromatograms for Evaluation of Peak Detection Methods Metabolites doi: 10.3390/metabo10040162 Authors: Erik Müller Carolin Huber Liza-Marie Beckers Werner Brack Martin Krauss Tobias Schulze Non-targeted mass spectrometry (MS) has become an important method over recent years in the fields of metabolomics and environmental research. While more and more algorithms...
Wed Apr 22, 2020 03:00
Microorganisms, Vol. 8, Pages 606: Butyrate Conversion by Sulfate-Reducing and Methanogenic Communities from Anoxic Sediments of Aarhus Bay, Denmark Microorganisms doi: 10.3390/microorganisms8040606 Authors: Derya Ozuolmez Elisha K. Moore Ellen C. Hopmans Jaap S. Sinninghe Damsté Alfons J. M. Stams Caroline M. Plugge The conventional perception that the zone of sulfate reduction and methanogenesis are separated in high- and low-sulfate-containing marine sediments has recently...
Wed Apr 22, 2020 03:00
Microorganisms, Vol. 8, Pages 607: Expression of Bacillus cereus Virulence-Related Genes in an Ocular Infection-Related Environment Microorganisms doi: 10.3390/microorganisms8040607 Authors: Phillip S. Coburn Frederick C. Miller Morgan A. Enty Craig Land Austin L. LaGrow Md Huzzatul Mursalin Michelle C. Callegan Bacillus cereus produces many factors linked to pathogenesis and is recognized for causing gastrointestinal toxemia and infections. B. cereus also causes a...
Wed Apr 22, 2020 03:00
Microorganisms, Vol. 8, Pages 608: Isolation, Identification and Characterization of Endophytic Bacterium Rhizobium oryzihabitans sp. nov., from Rice Root with Biotechnological Potential in Agriculture Microorganisms doi: 10.3390/microorganisms8040608 Authors: Juanjuan Zhao Xia Zhao Junru Wang Qi Gong Xiaoxia Zhang Guishan Zhang A flagellate, rod–shaped bacterium designated strain M15T was isolated from rice roots. Phylogenetic analysis based on the sequences...
Wed Apr 22, 2020 03:00
Molecules, Vol. 25, Pages 1951: Depolarization Ratios of Methane Raman Bands as a Function of Pressure Molecules doi: 10.3390/molecules25081951 Authors: Petrov In this work, we measured the intensities of Q-branches of the ν1, ν2 and ν3 bands in the polarized and depolarized methane Raman spectra in the pressure range of 1–60 atm. It was established that the pressure dependence of depolarization ratios of the ν2 and ν3 bands are negligible....
Wed Apr 22, 2020 03:00
Molecules, Vol. 25, Pages 1953: Conversion and Hydrothermal Decomposition of Major Components of Mint Essential Oil by Small-Scale Subcritical Water Treatment Molecules doi: 10.3390/molecules25081953 Authors: Chiou Nomura Konishi Liao Shimotori Murata Ohtsu Kohari Lee Tsai Nagata Saitoh Thermal stabilities of four major components (l-menthol, l-menthone, piperitone, and l-menthyl acetate) of Japanese mint essential oil were evaluated via subcritical...
Wed Apr 22, 2020 03:00
Molecules, Vol. 25, Pages 1952: Computer-Driven Development of an in Silico Tool for Finding Selective Histone Deacetylase 1 Inhibitors Molecules doi: 10.3390/molecules25081952 Authors: Sirous Campiani Brogi Calderone Chemi Histone deacetylases (HDACs) are a class of epigenetic modulators overexpressed in numerous types of cancers. Consequently, HDAC inhibitors (HDACIs) have emerged as promising antineoplastic agents. Unfortunately, the most developed HDACIs suffer from...
Wed Apr 22, 2020 03:00
Molecules, Vol. 25, Pages 1950: Palladium-Catalysed Coupling Reactions En Route to Molecular Machines: Sterically Hindered Indenyl and Ferrocenyl Anthracenes and Triptycenes, and Biindenyls Molecules doi: 10.3390/molecules25081950 Authors: McGlinchey Nikitin Pd-catalysed Stille and Suzuki cross-couplings were used to prepare 9-(3-indenyl)-, 6, and 9-(2-indenyl)-anthracene, 7; addition of benzyne led to the 9-Indenyl-triptycenes, 8 and 9. In 6, [4 + 2] addition also occurred to the...
Wed Apr 22, 2020 03:00
Molecules, Vol. 25, Pages 1954: Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees Molecules doi: 10.3390/molecules25081954 Authors: Yaremenko Syromyatnikov Radulov Belyakova Fomenkov Popov Terent’ev In recent years, the number of pollinators in the world has significantly decreased. A possible reason for this is the toxic effects of agrochemicals reducing the immunity of insects that leads...
Wed Apr 22, 2020 03:00
Molecules, Vol. 25, Pages 1947: The Synergistic Antitumor Effect of 5-Fluorouracil Combined with Allicin against Lung and Colorectal Carcinoma Cells Molecules doi: 10.3390/molecules25081947 Authors: Adrian Bogdan Țigu Vlad-Alexandru Toma Augustin Cătălin Moț Ancuța Jurj Cristian Silviu Moldovan Eva Fischer-Fodor Ioana Berindan-Neagoe Marcel Pârvu 5-fluorouracil (5-FU) is an anticancer drug used to inhibit the proliferation of many different tumor cells. Since severe...
Wed Apr 22, 2020 03:00
Molecules, Vol. 25, Pages 1938: Simultaneous Analysis of Fenthion and Its Five Metabolites in Produce Using Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry Molecules doi: 10.3390/molecules25081938 Authors: Jonghwa Lee Jeong-Han Kim A simultaneous analytical method for the organophosphorus insecticide fenthion and its five metabolites (fenthion oxon, fenthion oxon sulfoxide, fenthion oxon sulfone, fenthion sulfoxide, and fenthion sulfone) was developed based on...
Wed Apr 22, 2020 03:00
Molecules, Vol. 25, Pages 1949: Biodegradable Cell Microcarriers Based on Chitosan/Polyester Graft-Copolymers Molecules doi: 10.3390/molecules25081949 Authors: Tatiana S. Demina Maria G. Drozdova Chantal Sevrin Philippe Compère Tatiana A. Akopova Elena Markvicheva Christian Grandfils Self-stabilizing biodegradable microcarriers were produced via an oil/water solvent evaporation technique using amphiphilic chitosan-g-polyester copolymers as a core material in oil phase...
Wed Apr 22, 2020 03:00
Molecules, Vol. 25, Pages 1946: Structure-Dependent Activity of Plant-Derived Sweeteners Molecules doi: 10.3390/molecules25081946 Authors: Serhat Sezai Ҫiçek Human sensation for sweet tastes and the thus resulting over-consumption of sugar in recent decades has led to an increasing number of people suffering from caries, diabetes, and obesity. Therefore, a demand for sugar substitutes has arisen, which increasingly has turned towards natural sweeteners over the last 20 years. In the...
Wed Apr 22, 2020 03:00
Molecules, Vol. 25, Pages 1944: Microwave-Assisted Heating Reactions of N-Acetylglucosamine (GlcNAc) in Sulfolane as a Method Generating 1,6-Anhydrosugars Consisting of Amino Monosaccharide Backbones Molecules doi: 10.3390/molecules25081944 Authors: Harumi Kaga Masaru Enomoto Hiroki Shimizu Izuru Nagashima Keigo Matsuda Seigou Kawaguchi Atsushi Narumi The microwave-assisted heating reaction of N-acetyl glucosamine (GlcNAc) in sulfolane is described. The reaction produces...
Wed Apr 22, 2020 03:00
Molecules, Vol. 25, Pages 1941: The Toxicological Aspects of the Heat-Borne Toxicant 5-Hydroxymethylfurfural in Animals: A Review Molecules doi: 10.3390/molecules25081941 Authors: Mayada R. Farag Mahmoud Alagawany May Bin-Jumah Sarah I. Othman Asmaa F. Khafaga Hazem M. Shaheen Dalia Samak Abdelrazeq M. Shehata Ahmed A. Allam Mohamed E. Abd El-Hack The incidence of adverse reactions in food is very low, however, some food products contain toxins formed naturally...
Wed Apr 22, 2020 03:00
Molecules, Vol. 25, Pages 1945: Testing for Ketoprofen Binding to HSA Coated Magnetic Nanoparticles under Normal Conditions and after Oxidative Stress Molecules doi: 10.3390/molecules25081945 Authors: Marta Ziegler-Borowska Kinga Mylkie Pawel Nowak Patryk Rybczynski Adam Sikora Dorota Chelminiak-Dudkiewicz Anna Kaczmarek-Kedziera Binding and transport of ligands is one of the most important functions of human blood serum proteins. Human serum albumin is found in plasma...
Wed Apr 22, 2020 03:00
Molecules, Vol. 25, Pages 1942: Palmitoylation of Metazoan Carotenoid Oxygenases Molecules doi: 10.3390/molecules25081942 Authors: Sheetal Uppal Igor B. Rogozin T.Michael Redmond Eugenia Poliakov Abundant in nature, carotenoids are a class of fat-soluble pigments with a polyene tetraterpenoid structure. They possess antioxidant properties and their consumption leads to certain health benefits in humans. Carotenoid cleavage oxygenases (CCOs) are a superfamily of enzymes which...
Wed Apr 22, 2020 03:00
Molecules, Vol. 25, Pages 1943: Phase Transformations and Photocatalytic Activity of Nanostructured Y2O3/TiO2-Y2TiO5 Ceramic Such as Doped with Carbon Nanotubes Molecules doi: 10.3390/molecules25081943 Authors: Artem L. Kozlovskiy Inesh Z. Zhumatayeva Dina Mustahieva Maxim V. Zdorovets This work is devoted to the study of phase transition processes in nanostructured ceramics of the Y2O3/TiO2-Y2TiO5 type doped with carbon nanotubes as a result of thermal annealing, as well as...
Wed Apr 22, 2020 03:00
Molecules, Vol. 25, Pages 1939: Higher Gene Expression Related to Wound Healing by Fibroblasts on Silk Fibroin Biomaterial than on Collagen Molecules doi: 10.3390/molecules25081939 Authors: Hashimoto Kojima Tamada Silk fibroin (SF), which offers the benefits of biosafety, biocompatibility, and mechanical strength, has potential for use as a good biomedical material, especially in the tissue engineering field. This study investigated the use of SF biomaterials as a wound dressing...
Wed Apr 22, 2020 03:00
Molecules, Vol. 25, Pages 1940: Structural and Functional Characterization of NadR from Lactococcus lactis Molecules doi: 10.3390/molecules25081940 Authors: Artem Stetsenko Rajkumar Singh Michael Jaehme Albert Guskov Dirk Jan Slotboom NadR is a bifunctional enzyme that converts nicotinamide riboside (NR) into nicotinamide mononucleotide (NMN), which is then converted into nicotinamide adenine dinucleotide (NAD). Although a crystal structure of the enzyme from the Gram-negative...
Wed Apr 22, 2020 03:00
Molecules, Vol. 25, Pages 1934: Synthesis and Structure Insights of Two Novel Broad-Spectrum Antibacterial Candidates Based on (E)-N′-[(Heteroaryl)methylene]adamantane-1-carbohydrazides Molecules doi: 10.3390/molecules25081934 Authors: Lamya H. Al-Wahaibi Natalia Alvarez Olivier Blacque Nicolás Veiga Aamal A. Al-Mutairi Ali A. El-Emam Two new N′-heteroarylidene-1-carbohydrazide derivatives, namely; E-N′-[(pyridine-3-yl)methylidene]adamantane-1-carbohydrazide...
Wed Apr 22, 2020 03:00
Molecules, Vol. 25, Pages 1936: Potential Decontamination of Drinking Water Pathogens through K-Carrageenan Integrated Green Bottle Fly Bio-Synthesized Silver Nanoparticles Molecules doi: 10.3390/molecules25081936 Authors: M. A. Abu-Saied Mohamed Elnouby Tarek Taha Muhammad El-shafeey Ali G. Alshehri Saad Alamri Huda Alghamdi Ali Shati Sulaiman Alrumman Mohamed Al-Kahtani Mahmoud Moustafa The wide distribution of infections-related pathogenic microbes is...
Wed Apr 22, 2020 03:00
Molecules, Vol. 25, Pages 1935: Traps and Pitfalls—Unspecific Reactions in Metabolic Engineering of Sesquiterpenoid Pathways Molecules doi: 10.3390/molecules25081935 Authors: Maximilian Frey The characterization of plant enzymes by expression in prokaryotic and eukaryotic (yeast and plants) heterologous hosts has widely been used in recent decades to elucidate metabolic pathways in plant secondary metabolism. Yeast and plant systems provide the cellular environment of a eukaryotic cell...
Wed Apr 22, 2020 03:00
Molecules, Vol. 25, Pages 1917: Aesculus hippocastanum L. Extract Does Not Induce Fibroblast to Myofibroblast Conversion but Increases Extracellular Matrix Production In Vitro Leading to Increased Wound Tensile Strength in Rats Molecules doi: 10.3390/molecules25081917 Authors: Ivan Kováč Nikola Melegová Matúš Čoma Peter Takáč Katarína Kováčová Martin Hollý Ján Ďurkáč Lukáš Urban Miriam Gurbáľová Emil Švajdlenka Gabriela Mojžišová Robert Zajíček Pavol Szabo...
Wed Apr 22, 2020 03:00
Molecules, Vol. 25, Pages 1937: Metabolic-Hydroxy and Carboxy Functionalization of Alkyl Moieties in Drug Molecules: Prediction of Structure Influence and Pharmacologic Activity Molecules doi: 10.3390/molecules25081937 Authors: Babiker M. El-Haj Samrein B.M. Ahmed Alkyl moieties—open chain or cyclic, linear, or branched—are common in drug molecules. The hydrophobicity of alkyl moieties in drug molecules is modified by metabolic hydroxy functionalization via free-radical...
Wed Apr 22, 2020 03:00
MTI, Vol. 4, Pages 13: PERSEL, a Ready-to-Use PERsonality-Based User SELection Tool to Maximize User Experience Redesign Effectiveness Multimodal Technologies and Interaction doi: 10.3390/mti4020013 Authors: Stefano Filippi Some literature has already demonstrated the widespread influence of human personality on product design. Nevertheless, most of the existing user experience (UX) design methods and tools do not fully exploit knowledge about user personality in selecting the best participants...
Wed Apr 22, 2020 03:00
Nanomaterials, Vol. 10, Pages 804: A Nano-Rattle SnO2@carbon Composite Anode Material for High-Energy Li-ion Batteries by Melt Diffusion Impregnation Nanomaterials doi: 10.3390/nano10040804 Authors: Maharajan Kwon Brodard Fromm The huge volume expansion in Sn-based alloy anode materials (up to 360%) leads to a dramatic mechanical stress and breaking of particles, resulting in the loss of conductivity and thereby capacity fading. To overcome this issue, SnO2@C nano-rattle...
Wed Apr 22, 2020 03:00
Nanomaterials, Vol. 10, Pages 803: Conductive Atomic Force Microscopy of Semiconducting Transition Metal Dichalcogenides and Heterostructures Nanomaterials doi: 10.3390/nano10040803 Authors: Giannazzo Schilirò Greco Roccaforte Semiconducting transition metal dichalcogenides (TMDs) are promising materials for future electronic and optoelectronic applications. However, their electronic properties are strongly affected by peculiar nanoscale defects/inhomogeneities (point or...
Wed Apr 22, 2020 03:00
Nutrients, Vol. 12, Pages 1178: Retraction: Nassef, Y. et al. The Impact of Aerobic Exercise and Badminton on HDL Cholesterol Levels in Adult Taiwanese. Nutrients 2019, 11, 515 Nutrients doi: 10.3390/nu12041178 Authors: Nutrients Editorial Office Nutrients Editorial Office The published article [...]
Wed Apr 22, 2020 03:00
Nutrients, Vol. 12, Pages 1176: Acute Ingestion of A Novel Nitrate-Rich Dietary Supplement Significantly Increases Plasma Nitrate/Nitrite in Physically Active Men and Women Nutrients doi: 10.3390/nu12041176 Authors: Bloomer Butawan Pigg Martin Background: Dietary supplements purported to increase circulating nitric oxide are very popular among consumers. We determined the acute impact of two novel dietary supplements on plasma nitrate/nitrite (NOx) and nitrite alone. Methods:...
Wed Apr 22, 2020 03:00
Nutrients, Vol. 12, Pages 1177: Acute Effect of the Timing of Resistance Exercise and Nutrient Intake on Muscle Protein Breakdown Nutrients doi: 10.3390/nu12041177 Authors: Kume Yasuda Hashimoto Background: Combining resistance exercise (RE) with nutrient intake stimulates muscle protein net balance. However, it is still unclear whether the optimal timing of nutrient intake is before or after RE, especially on muscle protein breakdown (MPB) for an augmented muscle anabolic response....
Wed Apr 22, 2020 03:00
Nutrients, Vol. 12, Pages 1175: Glycomacropeptide Prevents Iron/Ascorbate-Induced Oxidative Stress, Inflammation and Insulin Sensitivity with an Impact on Lipoprotein Production in Intestinal Caco-2/15 Cells Nutrients doi: 10.3390/nu12041175 Authors: Foisy-Sauvé Ahmarani Delvin Sané Spahis Levy Background. Metabolic Syndrome (MetS), a major worldwide concern for the public health system, refers to a cluster of key metabolic components, and represents a risk factor...
Wed Apr 22, 2020 03:00
Nutrients, Vol. 12, Pages 1179: Omega-3 Fatty Acids and Eye Health: Opinions and Self-Reported Practice Behaviors of Optometrists in Australia and New Zealand Nutrients doi: 10.3390/nu12041179 Authors: Zhang Singh Craig Downie This study investigated optometrists’ attitudes and self-reported practice behaviors towards omega-3 fatty acids for eye health, and knowledge and understanding of their potential risks and benefits. An anonymous online survey was distributed...
Wed Apr 22, 2020 03:00
Nutrients, Vol. 12, Pages 1174: Facial EMG Correlates of Subjective Hedonic Responses During Food Consumption Nutrients doi: 10.3390/nu12041174 Authors: Wataru Sato Kazusa Minemoto Akira Ikegami Makoto Nakauma Takahiro Funami Tohru Fushiki An exploration of physiological correlates of subjective hedonic responses while eating food has practical and theoretical significance. Previous psychophysiological studies have suggested that some physiological measures, including...
Wed Apr 22, 2020 03:00
Nutrients, Vol. 12, Pages 1173: Lysophosphatidylcholine Containing Anisic Acid Is Able to Stimulate Insulin Secretion Targeting G Protein Coupled Receptors Nutrients doi: 10.3390/nu12041173 Authors: Anna Drzazga Marta Okulus Magdalena Rychlicka Łukasz Biegała Anna Gliszczyńska Edyta Gendaszewska-Darmach Diabetes mellitus is a worldwide health problem with high rates of mortality and morbidity. Management of diabetes mellitus by dietary components is achievable especially...
Wed Apr 22, 2020 03:00
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