Cells, Vol. 9, Pages 982: Necroptosis in Cholangiocarcinoma Cells doi: 10.3390/cells9040982 Authors: Samantha Sarcognato Iris E. M. de Jong Luca Fabris Massimiliano Cadamuro Maria Guido Necroptosis is a type of regulated cell death that is increasingly being recognized as a relevant pathway in different pathological conditions. Necroptosis can occur in response to multiple stimuli, is triggered by the activation of death receptors, and is regulated by receptor-interacting...
Cells, Vol. 9, Pages 971: Chromosome Dynamics Regulating Genomic Dispersion and Alteration of Nucleolus Organizer Regions (NORs) Cells doi: 10.3390/cells9040971 Authors: Hirohisa Hirai The nucleolus organizer regions (NORs) demonstrate differences in genomic dispersion and transcriptional activity among all organisms. I postulate that such differences stem from distinct genomic structures and their interactions from chromosome observations using fluorescence in situ hybridization and...
Cells, Vol. 9, Pages 973: Older Adults with Physical Frailty and Sarcopenia Show Increased Levels of Circulating Small Extracellular Vesicles with a Specific Mitochondrial Signature Cells doi: 10.3390/cells9040973 Authors: Anna Picca Raffaella Beli Riccardo Calvani Hélio José Coelho-Júnior Francesco Landi Roberto Bernabei Cecilia Bucci Flora Guerra Emanuele Marzetti Mitochondrial dysfunction and systemic inflammation are major factors in the development of sarcopenia,...
Cells, Vol. 9, Pages 981: Oxidized Phospholipids in Healthy and Diseased Lung Endothelium Cells doi: 10.3390/cells9040981 Authors: Pratap Karki Konstantin G. Birukov Circulating and cell membrane phospholipids undergo oxidation caused by enzymatic and non-enzymatic mechanisms. As a result, a diverse group of bioactive oxidized phospholipids generated in these conditions have both beneficial and harmful effects on the human body. Increased production of oxidized phospholipid products...
Cells, Vol. 9, Pages 976: The Osteosarcoma Microenvironment: A Complex But Targetable Ecosystem Cells doi: 10.3390/cells9040976 Authors: Isabelle Corre Franck Verrecchia Vincent Crenn Francoise Redini Valérie Trichet Osteosarcomas are the most frequent primary bone sarcomas, affecting mainly children, adolescents, and young adults, and with a second peak of incidence in elderly individuals. The current therapeutic management, a combined regimen of poly-chemotherapy and surgery,...
Cells, Vol. 9, Pages 974: The Essential Role of anxA2 in Langerhans Cell Birbeck Granules Formation Cells doi: 10.3390/cells9040974 Authors: Shantae M. Thornton Varsha D. Samararatne Joseph G. Skeate Christopher Buser Kim P. Lühen Julia R. Taylor Diane M. Da Da Silva W. Martin Kast Langerhans cells (LC) are the resident antigen presenting cells of the mucosal epithelium and play an essential role in initiating immune responses. LC are the only cells in the body to...
Cells, Vol. 9, Pages 977: Circulating Brain Injury Exosomal Proteins following Moderate-To-Severe Traumatic Brain Injury: Temporal Profile, Outcome Prediction and Therapy Implications Cells doi: 10.3390/cells9040977 Authors: Stefania Mondello Vivian Guedes Chen Lai Endre Czeiter Krisztina Amrein Firas Kobeissy Yehia Mechref Andreas Jeromin Sara Mithani Carina Martin Chelsea Wagner Andras Czigler Luca Tóth Bálint Fazekas Andras Buki Jessica Gill...
Cells, Vol. 9, Pages 972: The YAP/TAZ Pathway in Osteogenesis and Bone Sarcoma Pathogenesis Cells doi: 10.3390/cells9040972 Authors: Heinrich Kovar Lisa Bierbaumer Branka Radic-Sarikas YAP and TAZ are intracellular messengers communicating multiple interacting extracellular biophysical and biochemical cues to the transcription apparatus in the nucleus and back to the cell/tissue microenvironment interface through the regulation of cytoskeletal and extracellular matrix components....
Cells, Vol. 9, Pages 970: Activation of the PI3K-AKT Pathway by Old World Alphaviruses Cells doi: 10.3390/cells9040970 Authors: Eline Van Huizen Gerald M. McInerney Alphaviruses can infect a broad range of vertebrate hosts, including birds, horses, primates, and humans, in which infection can lead to rash, fever, encephalitis, and arthralgia or arthritis. They are most often transmitted by mosquitoes in which they establish persistent, asymptomatic infections. Currently, there are...
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Chemosensors, Vol. 8, Pages 28: Electrochemical Aptasensor for Detection of Dopamine Chemosensors doi: 10.3390/chemosensors8020028 Authors: Hisham Abu-Ali Cansu Ozkaya Frank Davis Nik Walch Alexei Nabok This work presents a proof of concept of a novel, simple, and sensitive method of detection of dopamine, a neurotransmitter within the human brain. We propose a simple electrochemical method for the detection of dopamine using a dopamine-specific aptamer labeled with an electrochemically...
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Clocks & Sleep, Vol. 2, Pages 153-171: Psychological Screening for Exceptional Environments: Laboratory Circadian Rhythm and Sleep Research Clocks & Sleep doi: 10.3390/clockssleep2020013 Authors: Amira Bressler Lee Czeisler Duffy Selecting participants who constitute a representative sample while protecting them from potential adverse outcomes is a concern for clinical researchers. Our research group conducts deep phenotyping studies of the circadian timing system...
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Diagnostics, Vol. 10, Pages 223: Comparative Study Regarding the Properties of Methylene Blue and Proflavine and Their Optimal Concentrations for In Vitro and In Vivo Applications Diagnostics doi: 10.3390/diagnostics10040223 Authors: Nedu Tertis Cristea Georgescu Methylene blue and proflavine are fluorescent dyes used to stain nucleic acid from the molecular level to the tissue level. Already clinically used for sentinel node mapping, detection of neuroendocrine tumors,...
Diagnostics, Vol. 10, Pages 221: Benign Biliary Strictures: A Systematic Review on Endoscopic Treatment Options Diagnostics doi: 10.3390/diagnostics10040221 Authors: Wong Saxena Kaffes Benign biliary strictures can be difficult to manage. Untreated biliary strictures can lead to complications, such as chronic cholestasis, jaundice, recurrent sepsis, and secondary biliary cirrhosis, which can have severe ramifications. The management landscape is constantly evolving, with the...
Diagnostics, Vol. 10, Pages 222: Salivary Cytokines and Airways Disease Severity in Patients with Cystic Fibrosis Diagnostics doi: 10.3390/diagnostics10040222 Authors: Alice Castaldo Paola Iacotucci Vincenzo Carnovale Roberta Cimino Renato Liguori Marika Comegna Valeria Raia Gaetano Corso Giuseppe Castaldo Monica Gelzo About 50% of patients with cystic fibrosis (CF) have sinonasal complications, which include inferior turbinate hypertrophy (NTH) and/or nasal...
Diagnostics, Vol. 10, Pages 220: Diagnosis of Dizziness Due to a Core Vestibular Projection Injury in a Patient with Intracerebral Hemorrhage Diagnostics doi: 10.3390/diagnostics10040220 Authors: Hyeok Gyu Kwon Chul Hoon Chang Sung Ho Jang Herein, we present a patient diagnosed with dizziness due to a core vestibular projection injury following intracerebral hemorrhage (ICH). A 51-year-old female patient underwent conservative management for a spontaneous ICH in the left hemisphere...
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Diseases, Vol. 8, Pages 9: From Donor to Patient: Collection, Preparation and Cryopreservation of Fecal Samples for Fecal Microbiota Transplantation Diseases doi: 10.3390/diseases8020009 Authors: Carole Nicco Armelle Paule Peter Konturek Marvin Edeas Fecal Microbiota Transplantation (FMT) is suggested as an efficacious therapeutic strategy for restoring intestinal microbial balance, and thus for treating disease associated with alteration of gut microbiota. FMT consists of the...
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Environments, Vol. 7, Pages 32: Macromolecular Structure of a Commercial Humic Acid Sample Environments doi: 10.3390/environments7040032 Authors: Sante Capasso Simeone Chianese Dino Musmarra Pasquale Iovino The molecular structure of a commercial sample of humic acids (HA) was investigated by membrane dialysis experiments (MD) and low-pressure size-exclusion chromatography (LP-SEC). MD showed that HA molecules were retained by dialysis membrane with a cut-off of 6–8...
Environments, Vol. 7, Pages 33: The Spatial and Temporal Variability of the Effects of Agricultural Practices on the Environment Environments doi: 10.3390/environments7040033 Authors: Rosa Maria Fanelli It is widely known that agricultural practices can alter natural ecosystems, both from a qualitative and quantitative point of view. Indeed, over the years, the intensification of production through excessive or inappropriate use of pesticides and fertilisers in the agricultural sector...
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EJIHPE, Vol. 10, Pages 579-594: The Development of a BMI-Guided Shape Morphing Technique and the Effects of an Individualized Figure Rating Scale on Self-Perception of Body Size European Journal of Investigation in Health, Psychology and Education doi: 10.3390/ejihpe10020043 Authors: Hudson Lu Zhang Hahn Zabal Latif Philbeck The creation of personalized avatars that may be morphed to simulate realistic changes in body size is useful when studying self-perception...
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Foods, Vol. 9, Pages 500: Integration of Partial Least Squares Regression and Hyperspectral Data Processing for the Nondestructive Detection of the Scaling Rate of Carp (Cyprinus carpio) Foods doi: 10.3390/foods9040500 Authors: Huihui Wang Kunlun Wang Xinyu Zhu Peng Zhang Jixin Yang Mingqian Tan The scaling rate of carp is one of the most important factors restricting the automation and intelligence level of carp processing. In order to solve the shortcomings of the commonly-used...
Foods, Vol. 9, Pages 499: Pinot Blanc: Impact of the Winemaking Variables on the Evolution of the Phenolic, Volatile and Sensory Profiles Foods doi: 10.3390/foods9040499 Authors: Amanda Dupas de Matos Edoardo Longo Danila Chiotti Ulrich Pedri Daniela Eisenstecken Christof Sanoll Peter Robatscher Emanuele Boselli The impact of two different winemaking practices on the chemical and sensory complexity of Pinot Blanc wines from South Tyrol (Italy), from grape pressing...
Foods, Vol. 9, Pages 498: The First Identification of the Uniqueness and Authentication of Maltese Extra Virgin Olive Oil Using 3D-Fluorescence Spectroscopy Coupled with Multi-Way Data Analysis Foods doi: 10.3390/foods9040498 Authors: Frederick Lia Jean Paul Formosa Marion Zammit-Mangion Claude Farrugia The potential application of multivariate three-way data analysis techniques, namely parallel factor analysis (PARAFAC) and discriminant multi-way partial least squares regression...
Foods, Vol. 9, Pages 497: How to Formulate for Structure and Texture via Medium of Additive Manufacturing-A Review Foods doi: 10.3390/foods9040497 Authors: Azarmidokht Gholamipour-Shirazi Michael-Alex Kamlow Ian T. Norton Tom Mills Additive manufacturing, which is also known as 3D printing, is an emerging and growing technology. It is providing significant innovations and improvements in many areas such as engineering, production, medicine, and more. 3D food printing is an area...
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Healthcare, Vol. 8, Pages 99: Epidemiology of Coronavirus COVID-19: Forecasting the Future Incidence in Different Countries Healthcare doi: 10.3390/healthcare8020099 Authors: Johannes Stübinger Lucas Schneider This paper forecasts the future spread of COVID-19 by exploiting the identified lead-lag effects between different countries. Specifically, we first determine the past relation among nations with the aid of dynamic time warping. This procedure allows an elastic adjustment of...
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Heritage, Vol. 3, Pages 243-274: Authenticity or Continuity in the Implementation of the UNESCO World Heritage Convention? Scrutinizing Statements of Outstanding Universal Value, 1978–2019 Heritage doi: 10.3390/heritage3020015 Authors: Roha W. Khalaf Continuity is a key theme in conservation and one that appears in the text of the UNESCO World Heritage Convention, which requests States Parties to continue to protect, conserve and present properties situated on their territories (Article...
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IJERPH, Vol. 17, Pages 2731: Moral Obligation, Public Leadership, and Collective Action for Epidemic Prevention and Control: Evidence from the Corona Virus Disease 2019 (COVID-19) Emergency International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082731 Authors: Liu Yang Yang Ren To investigate the effect of villagers’ moral obligation and village cadres’ public leadership on villagers’ collective action for epidemic prevention...
IJERPH, Vol. 17, Pages 2726: Neurocognitive Inhibitory Control Ability Performance and Correlations with Biochemical Markers in Obese Women International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082726 Authors: Huei-Jhen Wen Chia-Liang Tsai Inhibitory control, the ability to suppress prepotent responses and resist irrelevant stimuli, is thought to play a critical role in the maintenance of obesity. However, electrophysiological performance related to...
IJERPH, Vol. 17, Pages 2733: Risk Attitude, Contract Arrangements and Enforcement in Food Safety Governance: A China’s Agri-Food Supply Chain Scenario International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082733 Authors: Jing Hou Linhai Wu Bo Hou Frequent food safety problems in recent years have seriously affected China’s public health. The complexity, diversity, and technicality of food safety problems are intertwined, which constantly...
IJERPH, Vol. 17, Pages 2736: Association between Working Hours and Self-Rated Health International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082736 Authors: Jeon Lee Choi Ham Kang This study compared the association between working hours and self-rated health (SRH) according to sex, socioeconomic status, and working conditions. In all, 25,144 participants were selected from the Korea National Health and Nutrition Examination Survey (KNHANES),...
IJERPH, Vol. 17, Pages 2732: The Investigation of Gender Differences in Subjective Wellbeing in Children and Adolescents: The UP&DOWN Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082732 Authors: Sara Esteban-Gonzalo Laura Esteban-Gonzalo Verónica Cabanas-Sánchez Marta Miret Oscar L. Veiga Objective: Based on a three-factor model of subjective wellbeing (evaluative, hedonic and eudemonic), the purpose of this study was to...
IJERPH, Vol. 17, Pages 2734: Review: Sex-Specific Aspects in the Bariatric Treatment of Severely Obese Women International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082734 Authors: Jäger Wolicki Spohnholz Senkal This systematic literature review aims to point out sex-specific special features that are important in the bariatric treatment of women suffering from severe obesity. A systematic literature search was carried out according to Cochrane...
IJERPH, Vol. 17, Pages 2722: Beyond Mistreatment at the Relationship Level: Abusive Supervision and Illegitimate Tasks International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082722 Authors: Maie Stein Sylvie Vincent-Höper Marlies Schümann Sabine Gregersen According to the concept of abusive supervision, abusive supervisors display hostility towards their employees by humiliating and ridiculing them, giving them the silent treatment, and breaking...
IJERPH, Vol. 17, Pages 2721: Active Commuting and Physical Fitness: A Systematic Review International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082721 Authors: Duarte Henriques-Neto Miguel Peralta Susana Garradas Andreia Pelegrini André Araújo Pinto Pedro António Sánchez-Miguel Adilson Marques Physical fitness (PF) is considered an excellent biomarker of health. One possible strategy to improve PF levels is active commuting. This review,...
IJERPH, Vol. 17, Pages 2735: Fetuin-A and Fetuin-B in Non-Alcoholic Fatty Liver Disease: A Meta-Analysis and Meta-Regression International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082735 Authors: Xiongfeng Pan Atipatsa C. Kaminga Jihua Chen Miyang Luo Jiayou Luo The magnitude of the effect of fetuin-A and fetuin-B on non-alcoholic fatty liver disease (NAFLD) remains undefined. Therefore, the aim of this study was to synthesize previous findings...
IJERPH, Vol. 17, Pages 2717: Development and Evaluation of the Psychometric Properties of a Brief Wisdom Development Scale International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082717 Authors: Sai-fu Fung Esther Oi-wah Chow Chau-kiu Cheung This study was to develop an 18-item Brief Wisdom Development Scale, based on the original 66-item Wisdom Development Scale, and evaluate the psychometric properties of the proposed scale using a sample of older...
IJERPH, Vol. 17, Pages 2718: Low-Risk Planned Out-of-Hospital Births: Characteristics and Perinatal Outcomes in Different Italian Birth Settings International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082718 Authors: Marta Campiotti Rita Campi Michele Zanetti Paola Olivieri Alice Faggianelli Maurizio Bonati Background: The present observational study aimed to describe women and delivery characteristics and early birth outcomes according to...
IJERPH, Vol. 17, Pages 2728: Dynamics and Distribution of the Invasive Mosquito Aedes koreicus in a Temperate European City International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082728 Authors: Kurucz Manica Delucchi Kemenesi Marini Aedes koreicus is a mosquito species native to Asia that has recently successfully invaded new areas in several European countries. Here, we provide important data on Ae. koreicus establishment in Pécs...
IJERPH, Vol. 17, Pages 2727: Exploring the Environmental Exposure to Methoxychlor, α-HCH and Endosulfan–sulfate Residues in Lake Naivasha (Kenya) Using a Multimedia Fate Modeling Approach International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082727 Authors: Yasser Abbasi Chris M. Mannaerts Distribution of pesticide residues in the environment and their transport to surface water bodies is one of the most important environmental challenges. Fate of...
IJERPH, Vol. 17, Pages 2716: The Effects of Family Financial Stress and Primary Caregivers’ Levels of Acculturation on Children’s Emotional and Behavioral Problems among Humanitarian Refugees in Australia International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082716 Authors: Linlin Yu Andre M.N. Renzaho Lishuo Shi Li Ling Wen Chen The present study evaluated the application of the basic and extended (incorporated primary caregivers’...
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