Antibiotics, Vol. 9, Pages 183: Evaluation of Oxytetracycline Metabolites Cross-Reactivity with Oxytetracycline Enzyme-Linked Immunosorbent Assay (ELISA) Antibiotics doi: 10.3390/antibiotics9040183 Authors: Faraj Hijaz Nabil Killiny Antibiotics have been successfully used for the control of several plant diseases for many years. Recently, streptomycin and oxytetracycline have been approved for the treatment of Huanglongbing (HLB) in Florida. The enzyme-linked immunosorbent assay (ELISA)...
Wed Apr 15, 2020 03:00
Antibiotics, Vol. 9, Pages 181: Antimicrobial Activity of Silver-Treated Bacteria against other Multi-Drug Resistant Pathogens in Their Environment Antibiotics doi: 10.3390/antibiotics9040181 Authors: Doaa Safwat Mohamed Rehab Mahmoud Abd El-Baky Tim Sandle Sahar A. Mandour Eman Farouk Ahmed Silver is a potent antimicrobial agent against a variety of microorganisms and once the element has entered the bacterial cell, it accumulates as silver nanoparticles with large surface...
Wed Apr 15, 2020 03:00
Antibiotics, Vol. 9, Pages 182: Selective Modification of Streptozotocin at the C3 Position to Improve Its Bioactivity as Antibiotic and Reduce Its Cytotoxicity towards Insulin-Producing β Cells Antibiotics doi: 10.3390/antibiotics9040182 Authors: Ji Zhang Liubov Yakovlieva Bart J. de Haan Paul de Vos Adriaan J. Minnaard Martin D. Witte Marthe T. C. Walvoort With the increasing resistance of bacteria to current antibiotics, novel compounds are urgently needed to treat...
Wed Apr 15, 2020 03:00
Antibodies, Vol. 9, Pages 9: Exploration and Modulation of Antibody Fragment Biophysical Properties by Replacing the Framework Region Sequences Antibodies doi: 10.3390/antib9020009 Authors: Thomas Cnudde Zineb Lakhrif Justine Bourgoin Fanny Boursin Catherine Horiot Corinne Henriquet Anne di Tommaso Matthieu Olivier Juste Isabella Gizzi Jiacomini Isabelle Dimier-Poisson Martine Pugnière Marie-Nöelle Mévélec Nicolas Aubrey In order to increase the successful...
Wed Apr 15, 2020 03:00
Antioxidants, Vol. 9, Pages 318: Transcriptome Analyses of lncRNAs in A2E-Stressed Retinal Epithelial Cells Unveil Advanced Links between Metabolic Impairments Related to Oxidative Stress and Retinitis Pigmentosa Antioxidants doi: 10.3390/antiox9040318 Authors: Donato Scimone Alibrandi Rinaldi Sidoti D’Angelo : Long non-coding RNAs (lncRNAs) are untranslated transcripts which regulate many biological processes. Changes in lncRNA expression pattern are well-known...
Wed Apr 15, 2020 03:00
Antioxidants, Vol. 9, Pages 314: Wild and Cultivated Centaurea raphanina subsp. mixta: A Valuable Source of Bioactive Compounds Antioxidants doi: 10.3390/antiox9040314 Authors: Petropoulos Fernandes Dias Pereira Calhelha Gioia Tzortzakis Ivanov Sokovic Barros Ferreira Centaurea raphanina subsp. mixta (DC.) Runemark is a wild edible species endemic to Greece. This study evaluated the chemical composition and bioactive properties of wild and cultivated...
Wed Apr 15, 2020 03:00
Antioxidants, Vol. 9, Pages 317: Regular Intake of Pistachio Mitigates the Deleterious Effects of a High Fat-Diet in the Brain of Obese Mice Antioxidants doi: 10.3390/antiox9040317 Authors: Nuzzo Galizzi Amato Terzo Picone Cristaldi Mulè Di Carlo ：Obesity has been associated with neurodegeneration and cognitive dysfunctions. Recent data showed that pistachio consumption is able to prevent and ameliorate dyslipidemia, hepatic steatosis, systemic and adipose...
Wed Apr 15, 2020 03:00
Antioxidants, Vol. 9, Pages 315: Immunological Techniques to Assess Protein Thiol Redox State: Opportunities, Challenges and Solutions Antioxidants doi: 10.3390/antiox9040315 Authors: Cobley Husi To understand oxidative stress, antioxidant defense, and redox signaling in health and disease it is essential to assess protein thiol redox state. Protein thiol redox state is seldom assessed immunologically because of the inability to distinguish reduced and reversibly oxidized thiols...
Wed Apr 15, 2020 03:00
Antioxidants, Vol. 9, Pages 316: Improving Mental Performance in an Athletic Population with the Use of Ārepa®, a Blackcurrant Based Nootropic Drink: A Randomized Control Trial Antioxidants doi: 10.3390/antiox9040316 Authors: Natalie Gibson Dane Baker Alice Sharples Andrea Braakhuis A range of dietary bioactive ingredients have claimed to improve mental clarity and reduce fatigue, including blackcurrant, pine bark, and l-theanine. These active ingredients provide a good source...
Wed Apr 15, 2020 03:00
Antioxidants, Vol. 9, Pages 319: Increasing the Magnesium Concentration in Various Dialysate Solutions Differentially Modulates Oxidative Stress in a Human Monocyte Cell Line Antioxidants doi: 10.3390/antiox9040319 Authors: Vida Carracedo Sequera Bodega Pérez Alique Ramírez Oxidative stress is exacerbated in hemodialysis patients by several factors, including the uremic environment and the use of dialysis fluids (DFs). Since magnesium (Mg) plays a key role in...
Wed Apr 15, 2020 03:00
Antioxidants, Vol. 9, Pages 313: Oxidative Stress, a Crossroad Between Rare Diseases and Neurodegeneration Antioxidants doi: 10.3390/antiox9040313 Authors: Espinós Galindo García-Gimeno Ibáñez-Cabellos Martínez-Rubio Millán Rodrigo Sanz Seco-Cervera Sevilla Tapia Pallardó : Oxidative stress is an imbalance between production and accumulation of oxygen reactive species and/or reactive nitrogen species in cells and tissues, and the capacity...
Wed Apr 15, 2020 03:00
Antioxidants, Vol. 9, Pages 312: A Global Study by 1H NMR Spectroscopy and SPME-GC/MS of the in Vitro Digestion of Virgin Flaxseed Oil Enriched or not with Mono-, Di- or Tri-Phenolic Derivatives. Antioxidant Efficiency of These Compounds Antioxidants doi: 10.3390/antiox9040312 Authors: Jon Alberdi-Cedeño María L. Ibargoitia María D. Guillén The effect of enriching virgin flaxseed oil with dodecyl gallate, hydroxytyrosol acetate or gamma-tocopherol on its in vitro digestion is studied...
Wed Apr 15, 2020 03:00
Atmosphere, Vol. 11, Pages 392: Analysis of Sources and Trends in Agricultural GHG Emissions from Annex I Countries Atmosphere doi: 10.3390/atmos11040392 Authors: Elżbieta Wójcik-Gront The vast majority of the scientific community believe that anthropogenic greenhouse gas (GHG) emissions are the predominant cause of climate change. One of the GHG emission sources is agriculture. Following the International Panel on Climate Change (IPCC) guidelines regarding GHG emission calculation,...
Wed Apr 15, 2020 03:00
Atmosphere, Vol. 11, Pages 389: Cross Assessment of Twenty-One Different Methods for Missing Precipitation Data Estimation Atmosphere doi: 10.3390/atmos11040389 Authors: Armanuos Al-Ansari Yaseen The results of metrological, hydrological, and environmental data analyses are mainly dependent on the reliable estimation of missing data. In this study, 21 classical methods were evaluated to determine the best method for infilling the missing precipitation data in Ethiopia. The monthly...
Wed Apr 15, 2020 03:00
Atmosphere, Vol. 11, Pages 388: Examining the Direct and Indirect Effects of Climatic Variables on Plague Dynamics Atmosphere doi: 10.3390/atmos11040388 Authors: Ricci P.H. Yue Harry F. Lee Climate change can influence infectious disease dynamics both directly, by affecting the disease ecology, and indirectly, through altering economic systems. However, despite that climate-driven human plague dynamics have been extensively studied in recent years, little is known about the relative...
Wed Apr 15, 2020 03:00
Atmosphere, Vol. 11, Pages 390: Atmospheric Trace Metal Deposition near the Great Barrier Reef, Australia Atmosphere doi: 10.3390/atmos11040390 Authors: Strzelec Proemse Gault-Ringold Boyd Perron Schofield Ryan Ristovski Alroe Humphries Keywood Ward Bowie Keywords: aerosols; Fe solubility; leaching experiments; global Fe cycle; source apportionment; anthropogenic emissions
Wed Apr 15, 2020 03:00
Atmosphere, Vol. 11, Pages 391: Possible Increase of Vegetation Exposure to Spring Frost under Climate Change in Switzerland Atmosphere doi: 10.3390/atmos11040391 Authors: Ondřej Lhotka Stefan Brönnimann We assessed future changes in spring frost risk for the Aare river catchment that comprises the Swiss Plateau, the most important agricultural region of Switzerland. An ensemble of 15 bias-corrected regional climate model (RCM) simulations from the EXAR data set forced by the RCP...
Wed Apr 15, 2020 03:00
Atmosphere, Vol. 11, Pages 387: Analysis of Emission of Greenhouse Gases from Road Transport in Poland between 1990 and 2017 Atmosphere doi: 10.3390/atmos11040387 Authors: Katarzyna Bebkiewicz Zdzisław Chłopek Jakub Lasocki Krystian Szczepański Magdalena Zimakowska-Laskowska The paper provides the results of the inventory of greenhouse gases (GHGs) from road transport in Poland over the period 1990–2017. To estimate GHGs’ emission from road transport,...
Wed Apr 15, 2020 03:00
Behavioral Sciences, Vol. 10, Pages 78: Smoking Status and Well-Being of Underserved African American Older Adults Behavioral Sciences doi: 10.3390/bs10040078 Authors: Mohsen Bazargan Sharon Cobb Jessica Castro Sandoval Shervin Assari Purpose: This study investigated the association between current and past cigarette smoking, with four domains of well-being, namely, physical quality of life, mental quality of life, depressive symptoms, and self-rated health status (SRH), among...
Wed Apr 15, 2020 03:00
Behavioral Sciences, Vol. 10, Pages 77: Personal Values Associated with Prosocial Decisions Behavioral Sciences doi: 10.3390/bs10040077 Authors: Renata M. Heilman Petko Kusev Social situations require people to make complex decisions, sometimes involving different outcomes for the self and others. Considering the long-lasting interest scholars are showing in the topic of social decisions, the aim of the current article is to add to this research line by looking at personal values...
Wed Apr 15, 2020 03:00
Biomolecules, Vol. 10, Pages 612: Novel Apoptotic Mediators Identified by Conservation of Vertebrate Caspase Targets Biomolecules doi: 10.3390/biom10040612 Authors: Nina Gubina Dominique Leboeuf Konstantin Piatkov Maxim Pyatkov Caspases are proteases conserved throughout Metazoans and responsible for initiating and executing the apoptotic program. Currently, there are over 1800 known apoptotic caspase substrates, many of them known regulators of cell proliferation and death,...
Wed Apr 15, 2020 03:00
Biomolecules, Vol. 10, Pages 611: Anti-Inflammatory Functions of Alverine via Targeting Src in the NF-κB Pathway Biomolecules doi: 10.3390/biom10040611 Authors: Chae Young Lee Han Gyung Kim Sang Hee Park Seok Gu Jang Kyung Ja Park Dong Sam Kim Ji Hye Kim Jae Youl Cho Alverine, a smooth muscle relaxant, is used to relieve cramps or spasms of the stomach and intestine. Although the effects of alverine on spontaneous and induced contractile activity are well known,...
Wed Apr 15, 2020 03:00
Biomolecules, Vol. 10, Pages 604: Nicotinamide, Nicotinamide Riboside and Nicotinic Acid—Emerging Roles in Replicative and Chronological Aging in Yeast Biomolecules doi: 10.3390/biom10040604 Authors: Ivan Orlandi Lilia Alberghina Marina Vai Nicotinamide, nicotinic acid and nicotinamide riboside are vitamin B3 precursors of NAD+ in the human diet. NAD+ has a fundamental importance for cellular biology, that derives from its essential role as a cofactor of various metabolic redox...
Wed Apr 15, 2020 03:00
Biomolecules, Vol. 10, Pages 610: Photobiomodulation for Parkinson’s Disease in Animal Models: A Systematic Review Biomolecules doi: 10.3390/biom10040610 Authors: Farzad Salehpour Michael R Hamblin Photobiomodulation (PBM) might be an effective treatment for Parkinson’s disease (PD) in human patients. PBM of the brain uses red or near infrared light delivered from a laser or an LED at relatively low power densities, onto the head (or other body parts) to stimulate the brain...
Wed Apr 15, 2020 03:00
Biosensors, Vol. 10, Pages 39: Design and Fabrication of Capillary-Driven Flow Device for Point-Of-Care Diagnostics Biosensors doi: 10.3390/bios10040039 Authors: Sammer-ul Hassan Xunli Zhang Point-of-care (POC) diagnostics enables the diagnosis and monitoring of patients from the clinic or their home. Ideally, POC devices should be compact, portable and operatable without the requirement of expertise or complex fluid mechanical controls. This paper showcases a chip-and-dip device,...
Wed Apr 15, 2020 03:00
Brain Sciences, Vol. 10, Pages 236: Imaging Transcranial Direct Current Stimulation (tDCS) with Positron Emission Tomography (PET) Brain Sciences doi: 10.3390/brainsci10040236 Authors: Thorsten Rudroff Craig D. Workman Alexandra C. Fietsam Laura L. Boles Ponto Transcranial direct current stimulation (tDCS) is a form of non-invasive neuromodulation that is increasingly being utilized to examine and modify several cognitive and motor functions. Although tDCS holds great potential,...
Wed Apr 15, 2020 03:00
Cancers, Vol. 12, Pages 979: Hypoxia Inducible Factors’ Signaling in Pediatric High-Grade Gliomas: Role, Modelization and Innovative Targeted Approaches Cancers doi: 10.3390/cancers12040979 Authors: Quentin Fuchs Marina Pierrevelcin Melissa Messe Benoit Lhermitte Anne-Florence Blandin Christophe Papin Andres Coca Monique Dontenwill Natacha Entz-Werlé The brain tumor microenvironment has recently become a major challenge in all pediatric cancers, but especially...
Wed Apr 15, 2020 03:00
Cancers, Vol. 12, Pages 980: Cancer Classification at the Crossroads Cancers doi: 10.3390/cancers12040980 Authors: Antonino Carbone Internationally accepted classifications of malignant tumors, developed by the World Health Organization (WHO) and the Union for International Cancer Control (UICC), are based on the histotype, site of origin, morphologic grade, and spread of cancer throughout the body. The WHO classifications are the foundation of cancer diagnosis and the starting point...
Wed Apr 15, 2020 03:00
Cancers, Vol. 12, Pages 976: Worldwide Review and Meta-Analysis of Cohort Studies Measuring the Effect of Mammography Screening Programmes on Incidence-Based Breast Cancer Mortality Cancers doi: 10.3390/cancers12040976 Authors: Amanda Dibden Judith Offman Stephen W. Duffy Rhian Gabe In 2012, the Euroscreen project published a review of incidence-based mortality evaluations of breast cancer screening programmes. In this paper, we update this review to October 2019 and expand...
Wed Apr 15, 2020 03:00
Cancers, Vol. 12, Pages 981: Betulinic Acid-Mediated Tuning of PERK/CHOP Signaling by Sp1 Inhibition as a Novel Therapeutic Strategy for Glioblastoma Cancers doi: 10.3390/cancers12040981 Authors: Wei-Lun Lo Tsung-I Hsu Wen-Bin Yang Tzu-Jen Kao Ming-Hsiao Wu Yung-Ning Huang Shiu-Hwa Yeh Jian-Ying Chuang Patients with glioblastoma are at high risk of local recurrences after initial treatment with standard therapy, and recurrent tumor cells appear to be resistant to...
Wed Apr 15, 2020 03:00
Cancers, Vol. 12, Pages 982: Comparison of Minimally Invasive Versus Open Pancreatoduodenectomy for Pancreatic Ductal Adenocarcinoma: A Propensity Score Matching Analysis Cancers doi: 10.3390/cancers12040982 Authors: Jaewoo Kwon Ki Byung Song Seo Young Park Dakyum Shin Sarang Hong Yejong Park Woohyung Lee Jae Hoon Lee Dae Wook Hwang Song Cheol Kim Background: Few studies have compared perioperative and oncological outcomes between minimally invasive pancreatoduodenectomy...
Wed Apr 15, 2020 03:00
Cancers, Vol. 12, Pages 978: The Potential of Nanobody-Targeted Photodynamic Therapy to Trigger Immune Responses Cancers doi: 10.3390/cancers12040978 Authors: Irati Beltrán Hernández Mathieu L. Angelier Tommaso Del Buono D’Ondes Alessia Di Maggio Yingxin Yu Sabrina Oliveira Nanobody-targeted photodynamic therapy (NB-PDT) has been recently developed as a more tumor-selective approach rather than conventional photodynamic therapy (PDT). NB-PDT uses nanobodies that bind to...
Wed Apr 15, 2020 03:00
Cancers, Vol. 12, Pages 977: An Explorative Analysis of ABCG2/TOP-1 mRNA Expression as a Biomarker Test for FOLFIRI Treatment in Stage III Colon Cancer Patients: Results from Retrospective Analyses of the PETACC-3 Trial Cancers doi: 10.3390/cancers12040977 Authors: Jan Stenvang Eva Budinská Eric van van Cutsem Fred Bosman Vlad Popovici Nils Brünner Biomarker-guided treatment for patients with colon cancer is needed. We tested ABCG2 and topoisomerase 1 (TOP1) mRNA expression...
Wed Apr 15, 2020 03:00
Cancers, Vol. 12, Pages 975: Management of HPV-Related Squamous Cell Carcinoma of the Head and Neck: Pitfalls and Caveat Cancers doi: 10.3390/cancers12040975 Authors: Perri Longo Caponigro Sandomenico Guida Della Vittoria Scarpati Ottaiano Muto Ionna : Head and neck squamous cell carcinomas (HNSCCs) are a very heterogeneous group of malignancies arising from the upper aerodigestive tract. They show different clinical behaviors depending on their origin...
Wed Apr 15, 2020 03:00
Cancers, Vol. 12, Pages 974: Resveratrol Promotes Tumor Microvessel Growth via Endoglin and Extracellular Signal-Regulated Kinase Signaling Pathway and Enhances the Anticancer Efficacy of Gemcitabine against Lung Cancer Cancers doi: 10.3390/cancers12040974 Authors: San-Hai Qin Andy T. Y. Lau Zhan-Ling Liang Heng Wee Tan Yan-Chen Ji Qiu-Hua Zhong Xiao-Yun Zhao Yan-Ming Xu The synergistic anticancer effect of gemcitabine (GEM) and resveratrol (RSVL) has been noted...
Wed Apr 15, 2020 03:00
Cancers, Vol. 12, Pages 973: Involvement of MicroRNA-296 in the Inhibitory Effect of Epigallocatechin Gallate against the Migratory Properties of Anoikis-Resistant Nasopharyngeal Carcinoma Cells Cancers doi: 10.3390/cancers12040973 Authors: Chien-Hung Lin Hsin-Hui Wang Tsung-Hsien Chen Ming-Chang Chiang Peir-Haur Hung Yann-Jang Chen Short noncoding endogenous RNAs, including microRNAs (miRNAs), are associated with the development and metastasis of multiple cancers. Epigallocatechin...
Wed Apr 15, 2020 03:00
Cells, Vol. 9, Pages 978: Protein Phosphatases Type 2C Group A Interact with and Regulate the Stability of ACC Synthase 7 in Arabidopsis Cells doi: 10.3390/cells9040978 Authors: Małgorzata Marczak Agata Cieśla Maciej Janicki Anna Kasprowicz-Maluśki Piotr Kubiak Agnieszka Ludwików Ethylene is an important plant hormone that controls growth, development, aging and stress responses. The rate-limiting enzymes in ethylene biosynthesis, the 1-aminocyclopropane-1-carboxylate...
Wed Apr 15, 2020 03:00
Cells, Vol. 9, Pages 979: Cathepsins in the Pathophysiology of Mucopolysaccharidoses: New Perspectives for Therapy Cells doi: 10.3390/cells9040979 Authors: Valeria De Pasquale Anna Moles Luigi Michele Pavone Cathepsins (CTSs) are ubiquitously expressed proteases normally found in the endolysosomal compartment where they mediate protein degradation and turnover. However, CTSs are also found in the cytoplasm, nucleus, and extracellular matrix where they actively participate in cell...
Wed Apr 15, 2020 03:00
Cells, Vol. 9, Pages 980: Therapeutic Potential of Dental Pulp Stem Cells and Leukocyte- and Platelet-Rich Fibrin for Osteoarthritis Cells doi: 10.3390/cells9040980 Authors: Melissa Lo Monaco Pascal Gervois Joel Beaumont Peter Clegg Annelies Bronckaers Jean-Michel Vandeweerd Ivo Lambrichts Osteoarthritis (OA) is a degenerative and inflammatory joint disorder with cartilage loss. Dental pulp stem cells (DPSCs) can undergo chondrogenic differentiation and secrete growth...
Wed Apr 15, 2020 03:00
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