Surinder Singh Rana, Jimil Shah, Ravi K Sharma, Rajesh GuptaEndoscopic Ultrasound 2020 9(2):130-137 Background: Long-term indwelling transmural stents in patients with walled-off necrosis (WON) and disconnected pancreatic duct syndrome (DPDS) is an effective strategy to decrease risk of recurrence of pancreatic fluid collection (PFC). However, long-term studies on the safety and efficacy of this strategy are lacking. Methods: Retrospective analysis of database of patients with WON treated with...
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Alberto Larghi, Mihai Rimbaş, Gianenrico Rizzatti, Giuseppe Quero, Antonio Gasbarrini, Guido Costamagna, Sergio AlfieriEndoscopic Ultrasound 2020 9(2):76-82 Benign or malignant conditions can present as pancreatic solid lesions (PSLs), and a thorough diagnostic workup is necessary to differentiate them. The need to acquire a tissue sample to reach a definitive diagnosis should be stratified by the findings at multidetector computed tomography (MDCT) with a pancreatic protocol. Tissue biopsy is...
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Chieh Sian Koo, Khek Yu HoEndoscopic Ultrasound 2020 9(2):71-75
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Sabrina Gloria Giulia Testoni, Andrew James Healey, Christoph F Dietrich, Paolo Giorgio ArcidiaconoEndoscopic Ultrasound 2020 9(2):83-100 The development of curvilinear-array EUS and EUS-guided fine-needle aspiration (EUS-FNA) has led these approaches to become interventional procedures rather than purely diagnostic, as a minimally invasive antitumor therapeutic alternative to radiological and surgical treatments. The possibility to accurately position needle devices and to reach a deep target...
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Hirofumi Harima, Seiji Kaino, Yuko Fujimoto, Shogo Amano, Isao SakaidaEndoscopic Ultrasound 2020 9(2):141-142
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Banreet Singh Dhindsa, Harmeet Singh Mashiana, Amaninder Dhaliwal, Babu P Mohan, Mahendran Jayaraj, Harlan Sayles, Shailender Singh, Gordon Ohning, Ishfaq Bhat, Douglas G AdlerEndoscopic Ultrasound 2020 9(2):101-109 ERCP is the current procedure of choice for patients with jaundice caused by biliary obstruction. EUS-guided biliary drainage (EUS-BD) has emerged as an alternative to ERCP in patients requiring biliary drainage. The aim of the study was to conduct a systematic review and meta-analysis...
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Roberto Grassia, Nicola Imperatore, Pietro Capone, Fabrizio Cereatti, Edoardo Forti, Filippo Antonini, Giulia Paola Tanzi, Mario Martinotti, Federico Buffoli, Massimiliano Mutignani, Giampiero Macarri, Gianpiero Manes, Maurizio Vecchi, Germana De NucciEndoscopic Ultrasound 2020 9(2):122-129 Background and Objective: EUS-FNA sensitivity for malignancy in parenchymal masses of patients with concurrent chronic pancreatitis (CP) has been reported to be unsatisfactory. The aim of the present study was...
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Yoshitaro Yamamoto, Takeshi Ogura, Nobu Nishioka, Tadahiro Yamada, Masanori Yamada, Saori Ueno, Kazuhide HiguchiEndoscopic Ultrasound 2020 9(2):110-115 Background and Objective: EUS-guided hepaticogastrostomy (HGS) is performed for patients with advanced cancer because of poor prognosis and compromised status, and bile peritonitis may prove critical for such patients. This adverse event has the possibility of decreasing quality of life by prolonging the time until the start of oral intake, hospital...
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Marco Le Grazie, Stefano Francesco Crinò, Armando Gabbrielli, Giuseppe Malleo, Stefano Marletta, Paola CapelliEndoscopic Ultrasound 2020 9(2):138-140
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Mădălin Ionuţ Costache, Irina M Cazacu, Christoph F Dietrich, Maria Chiara Petrone, Paolo Giorgio Arcidiacono, Marc Giovannini, Erwan Bories, Julio Iglesias Garcia, Sun Siyu, Erwin Santo, Carmen Florina Popescu, Alina Constantin, Manoop S Bhutani, Adrian SaftoiuEndoscopic Ultrasound 2020 9(2):116-121 Background: Recent advances in EUS techniques (real-time EUS elastography and contrast-enhanced EUS) have allowed a better characterization of focal pancreatic masses. Mean strain histograms (SHs)...
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Takeshi Ogura, Saori Ueno, Nobu Nishioka, Masanori Yamada, Kazuhide HiguchiEndoscopic Ultrasound 2020 9(2):143-145
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Abstract Damage to the insular cortex has been shown to disrupt smoking behavior. However, whether smoking cessation outcomes are associated with abnormal functions of insula and its subregions remains unclear. In this study, we investigated the relationship between insular functions (interregional functional connectivity and regional activity) and treatment outcomes of cigarette smoking. Thirty treatment-seeking smokers were recruited into the treatment study and underwent...
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The original version of this article contained mistakes. The surname of Elisa Brietzke was misspelled as “Brietske”.
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The study of the potential contribution of low-dose exposure to environmental chemicals on the development of chronic conditions in human populations is often hampered by methodological issues, including exposure misclassification and the inability to assess biological effects in target organs. White adipose tissue (WAT) presents the unique feature of being both an advantageous matrix for assessing long-term exposure to mixtures of persistent organic pollutants and an interesting tissue to investigate...
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AimThis study summarised available evidence on the association between early and on-time retirement, compared with continued working, and mortality. Moreover, this study investigated whether and to what extent gender, adjustment for demographics and prior health status influence this association. MethodsA systematic literature search of longitudinal studies was conducted. A qualitative analysis of the included studies was performed, followed by a meta-regression analysis to assess the influence...
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Lesbian, gay, bisexual and trans+ (LGBT+) people report poorer health than the general population and worse experiences of healthcare particularly cancer, palliative/end-of-life, dementia and mental health provision. This is attributable to: (a) social inequalities, including ‘minority stress’; (b) associated health-risk behaviours (eg, smoking, excessive drug/alcohol use, obesity); (c) loneliness and isolation, affecting physical/mental health and mortality; (d) anticipated/experienced discrimination...
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BackgroundChildren residing in neighbourhoods of high deprivation are more likely to have poorer health, including excess body size. While the availability of unhealthy food outlets are increasingly considered important for excess child body size, less is known about how neighbourhood deprivation, unhealthy food outlets and unhealthy dietary behaviours are interlinked. MethodsThis study involves children aged 8–13 years (n=1029) and resided in Auckland, New Zealand. Unhealthy dietary behaviours...
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BackgroundSocial and biological circumstances at birth are established predictors of adult socioeconomic position (SEP). This study aims to assess the trends in these associations across two generations and examine the effects of parental early-life characteristics on descendants’ adult SEP. MethodsWe studied men and women born in the Uppsala University Hospital 1915–1929 (G1) and their offspring born 1932–1960 (G2). Data were collected in archives and routine registers. Adult SEP was assessed...
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Whitten T, Green MJ, Laurens KR, et al. Parental offending and children’s emergency department presentations in New South Wales, Australia. J Epidemiol Community Health 2019;73:832-838. The surname of the fifth author on this paper is misspelt. The correct spelling is Harris.
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BackgroundHigh-sensitivity C reactive protein (hsCRP) has been proposed as a marker of incident cardiovascular disease and vascular mortality, and may also be a marker of non-vascular mortality. However, most evidence comes from either North American or European cohorts. The present proposal aims to investigate the association of hsCRP with the risk of all-cause mortality in a multiethnic Brazilian population. MethodsBaseline data (2008–2010) of a cohort of 14 238 subjects participating in the...
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BackgroundWe used a relational social-class measure based on property ownership and managerial authority to analyse the longitudinal relationships between class, self-rated health (SRH) and mental illness. To our knowledge, this is the first study using a relational social-class measure to evaluate these relationships longitudinally. MethodsUsing Panel Study of Income Dynamics data from 1984 to 2017, we first assigned respondents aged 25–64 to the not in the labour force (NILF), worker, manager,...
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BackgroundUnemployment has been reported to be associated with an increased risk of mortality. While most available studies focused on the effects of temporary unemployment on mortality, it remains unclear whether similar trends can be found in subjects who were never employed or are retirement. Therefore, this study examined the associations between temporary unemployment, never employed and retirement, integrating the risk of all-cause and cause-specific mortality in US adults. MethodsData from...
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BackgroundA step change in the night environment is taking place, with the large-scale installation of bright, broad-spectrum road lighting such as white light-emitting diodes (LEDs). One justification for this is a reduction in road traffic collisions (RTCs). This study aimed to estimate the effect of new lighting on personal injury RTCs within a large UK city. MethodsWe analysed a 9-year time series of weekly RTC personal injury counts in 132 areas of the city using multilevel modelling. The...
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BackgroundDiarrhoea is the second-leading infectious cause of death in children younger than age 5 years. The global burden of severe diarrhoeal disease is concentrated in Africa and Southeast Asia, where a significant percentage of the population resides in low-resource settings. We aimed to quantitatively examine whether extending the duration of legislated paid maternity leave affected the prevalence of childhood diarrhoea in low-income and middle-income countries (LMICs). MethodsWe merged longitudinal...
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IntroductionLifestyle factors in combination have been hypothesised to be associated with the prevention of type 2 diabetes (T2D) and mortality among individuals with T2D. The aim was to conduct a systematic review and meta-analysis to quantify the association between lifestyle indices and incident T2D as well as mortality in individuals with T2D. MethodsPubMed and Web of Science were searched up to September 2019. We included prospective cohort studies investigating at least three lifestyle factors...
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BackgroundPoverty, unemployment and substance abuse are inter-related problems. This study evaluated the effectiveness of abstinence-contingent wage supplements in promoting drug abstinence and employment in unemployed adults in outpatient treatment for opioid use disorder. MethodsA randomised controlled trial was conducted in Baltimore, MD, from 2014 to 2019. After a 3-month abstinence initiation and training period, participants (n=91) were randomly assigned to a usual care control group that...
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Eurich D, Lee C, Zongo A, et al. Cohort study of medical cannabis authorisation and healthcare utilisation in 2014–2017 in Ontario, Canada. J Epidemiol Community Health 2020;74:299–304. doi: 10.1136/jech-2019-212438. The fourth author’s name is misspelt: ‘Jajett K Minhas-Sandhu’ should be ‘Jasjeet K Minhas-Sandhu.’
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Alcohol consumption during pregnancy represents a significant public health concern. It has several adverse health effects for both the mother and the developing fetus. This study aimed to estimate the pooled ...
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This Viewpoint discusses the long history of racial inequities that cause black populations in US cities to bear a disproportionate burden of COVID-19 illness and mortality and calls for a renewed commitment to eliminating disparities that have been made so starkly visible by the pandemic.
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This narrative medicine essay emphasizes the undue disease burden carried by minority populations in the COVID-19 pandemic and proposes collection and reporting of data by race/ethnicity and multilingual targeted educational efforts delivered by celebrities or faith leaders as first steps to reduce the imbalance.
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This study describes the prevalence of SARS-CoV-2 co-infection with noncoronavirus respiratory pathogens in a sample of symptomatic patients undergoing PCR testing in March 2020.
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Cancers, Vol. 12, Pages 979: Hypoxia Inducible Factors’ Signaling in Pediatric High-Grade Gliomas: Role, Modelization and Innovative Targeted Approaches Cancers doi: 10.3390/cancers12040979 Authors: Quentin Fuchs Marina Pierrevelcin Melissa Messe Benoit Lhermitte Anne-Florence Blandin Christophe Papin Andres Coca Monique Dontenwill Natacha Entz-Werlé The brain tumor microenvironment has recently become a major challenge in all pediatric cancers, but...
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Cancers, Vol. 12, Pages 980: Cancer Classification at the Crossroads Cancers doi: 10.3390/cancers12040980 Authors: Antonino Carbone Internationally accepted classifications of malignant tumors, developed by the World Health Organization (WHO) and the Union for International Cancer Control (UICC), are based on the histotype, site of origin, morphologic grade, and spread of cancer throughout the body. The WHO classifications are the foundation of cancer diagnosis and the starting...
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Cancers, Vol. 12, Pages 976: Worldwide Review and Meta-Analysis of Cohort Studies Measuring the Effect of Mammography Screening Programmes on Incidence-Based Breast Cancer Mortality Cancers doi: 10.3390/cancers12040976 Authors: Amanda Dibden Judith Offman Stephen W. Duffy Rhian Gabe In 2012, the Euroscreen project published a review of incidence-based mortality evaluations of breast cancer screening programmes. In this paper, we update this review to October 2019 and...
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Cancers, Vol. 12, Pages 981: Betulinic Acid-Mediated Tuning of PERK/CHOP Signaling by Sp1 Inhibition as a Novel Therapeutic Strategy for Glioblastoma Cancers doi: 10.3390/cancers12040981 Authors: Wei-Lun Lo Tsung-I Hsu Wen-Bin Yang Tzu-Jen Kao Ming-Hsiao Wu Yung-Ning Huang Shiu-Hwa Yeh Jian-Ying Chuang Patients with glioblastoma are at high risk of local recurrences after initial treatment with standard therapy, and recurrent tumor cells appear to be...
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Cancers, Vol. 12, Pages 982: Comparison of Minimally Invasive Versus Open Pancreatoduodenectomy for Pancreatic Ductal Adenocarcinoma: A Propensity Score Matching Analysis Cancers doi: 10.3390/cancers12040982 Authors: Jaewoo Kwon Ki Byung Song Seo Young Park Dakyum Shin Sarang Hong Yejong Park Woohyung Lee Jae Hoon Lee Dae Wook Hwang Song Cheol Kim Background: Few studies have compared perioperative and oncological outcomes between minimally invasive...
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Cancers, Vol. 12, Pages 978: The Potential of Nanobody-Targeted Photodynamic Therapy to Trigger Immune Responses Cancers doi: 10.3390/cancers12040978 Authors: Irati Beltrán Hernández Mathieu L. Angelier Tommaso Del Buono D’Ondes Alessia Di Maggio Yingxin Yu Sabrina Oliveira Nanobody-targeted photodynamic therapy (NB-PDT) has been recently developed as a more tumor-selective approach rather than conventional photodynamic therapy (PDT). NB-PDT uses nanobodies that...
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Cancers, Vol. 12, Pages 977: An Explorative Analysis of ABCG2/TOP-1 mRNA Expression as a Biomarker Test for FOLFIRI Treatment in Stage III Colon Cancer Patients: Results from Retrospective Analyses of the PETACC-3 Trial Cancers doi: 10.3390/cancers12040977 Authors: Jan Stenvang Eva Budinská Eric van van Cutsem Fred Bosman Vlad Popovici Nils Brünner Biomarker-guided treatment for patients with colon cancer is needed. We tested ABCG2 and topoisomerase 1 (TOP1)...
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Cancers, Vol. 12, Pages 975: Management of HPV-Related Squamous Cell Carcinoma of the Head and Neck: Pitfalls and Caveat Cancers doi: 10.3390/cancers12040975 Authors: Perri Longo Caponigro Sandomenico Guida Della Vittoria Scarpati Ottaiano Muto Ionna : Head and neck squamous cell carcinomas (HNSCCs) are a very heterogeneous group of malignancies arising from the upper aerodigestive tract. They show different clinical behaviors depending on...
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Cancers, Vol. 12, Pages 974: Resveratrol Promotes Tumor Microvessel Growth via Endoglin and Extracellular Signal-Regulated Kinase Signaling Pathway and Enhances the Anticancer Efficacy of Gemcitabine against Lung Cancer Cancers doi: 10.3390/cancers12040974 Authors: San-Hai Qin Andy T. Y. Lau Zhan-Ling Liang Heng Wee Tan Yan-Chen Ji Qiu-Hua Zhong Xiao-Yun Zhao Yan-Ming Xu The synergistic anticancer effect of gemcitabine (GEM) and resveratrol (RSVL) has...
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Cancers, Vol. 12, Pages 973: Involvement of MicroRNA-296 in the Inhibitory Effect of Epigallocatechin Gallate against the Migratory Properties of Anoikis-Resistant Nasopharyngeal Carcinoma Cells Cancers doi: 10.3390/cancers12040973 Authors: Chien-Hung Lin Hsin-Hui Wang Tsung-Hsien Chen Ming-Chang Chiang Peir-Haur Hung Yann-Jang Chen Short noncoding endogenous RNAs, including microRNAs (miRNAs), are associated with the development and metastasis of multiple cancers....
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