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Τρίτη 21 Απριλίου 2020

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Alterations in osteocyte mediated osteoclastogenesis during estrogen deficiency and under ROCK-II inhibition: An <em>in vitro</em> study using a novel postmenopausal multicellular niche model
Publication date: Available online 21 April 2020Source: Experimental Cell ResearchAuthor(s): Irene Simfia, Jessica Schiavi, Laoise M. McNamara
Experimental Cell Research
17h
Long non-coding RNA HNF1A-AS1 upregulates OTX1 to enhance angiogenesis in colon cancer via the binding of transcription factor PBX3
Publication date: Available online 20 April 2020Source: Experimental Cell ResearchAuthor(s): Jinbao Wu, Xianmei Meng, Yanbin Jia, Jianyuan Chai, Jing Wang, Xiaohui Xue, Tong Dang
Experimental Cell Research
17h
Protection by vitamin D against high-glucose-induced damage in retinal pigment epithelial cells
Publication date: Available online 20 April 2020Source: Experimental Cell ResearchAuthor(s): Ali Mohammad Tohari, Mohammad Almarhoun, Reem Hasaballah Alhasani, Lincoln Biswas, Xinzhi Zhou, James Reilly, Zhihong Zeng, Xinhua Shu
Experimental Cell Research
17h
Functionally analyzing the important roles of hepatocyte nuclear factor 3 (FoxA) in tumorigenesis
Publication date: Available online 20 April 2020Source: Biochimica et Biophysica Acta (BBA) - Reviews on CancerAuthor(s): Bing Gao, Wei Xie, Xueji Wu, Lei Wang, Jianping Guo
ScienceDirect Publication: Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
17h
Phase I expansion cohort to evaluate the combination of bevacizumab, sorafenib and low-dose cyclophosphamide in children and young adults with refractory or recurrent solid tumours
Publication date: June 2020Source: European Journal of Cancer, Volume 132Author(s): Sara M. Federico, Kenneth J. Caldwell, Mary B. McCarville, Vinay M. Daryani, Clinton F. Stewart, Shenghua Mao, Jianrong Wu, Andrew M. Davidoff, Victor M. Santana, Wayne L. Furman, Alberto S. Pappo, Fariba Navid
European Journal of Cancer
17h
An immune gene expression signature distinguishes central nervous system metastases from primary tumours in non–small-cell lung cancer
Publication date: June 2020Source: European Journal of Cancer, Volume 132Author(s): Georgios Tsakonas, Rolf Lewensohn, Johan Botling, Cristian Ortiz-Villalon, Patrick Micke, Signe Friesland, Helena Nord, Magnus Lindskog, Martin Sandelin, Per Hydbring, Simon Ekman
European Journal of Cancer
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Association of premenopausal risk-reducing salpingo-oophorectomy with breast cancer risk in <em>BRCA1/2</em> mutation carriers: Maximising bias-reduction
Publication date: June 2020Source: European Journal of Cancer, Volume 132Author(s): Neda Stjepanovic, Guillermo Villacampa, Kevin T. Nead, Sara Torres-Esquius, Guadalupe G. Melis, Katherine L. Nathanson, Alexandre Teule, Joan Brunet, Teresa R. y Cajal, Gemma Llort, Rodrigo Dienstmann, Montserrat Rue, Susan M. Domchek, Judith Balmaña
European Journal of Cancer
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Efficacy and safety of the therapeutic cancer vaccine tecemotide (L-BLP25) in early breast cancer: Results from a prospective, randomised, neoadjuvant phase II study (ABCSG 34)
Publication date: June 2020Source: European Journal of Cancer, Volume 132Author(s): Christian F. Singer, Georg Pfeiler, Michael Hubalek, Rupert Bartsch, Herbert Stöger, Angelika Pichler, Edgar Petru, Vesna Bjelic-Radisic, Richard Greil, Margaretha Rudas, Muy-Kheng Maria Tea, Viktor Wette, Andreas L. Petzer, Paul Sevelda, Daniel Egle, Peter C. Dubsky, Martin Filipits, Florian Fitzal, Ruth Exner, Raimund Jakesz
European Journal of Cancer
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Are Immunohistochemical Markers Useful in Phenotypic Gastric Cancer Classification?
To identify useful markers for prognostic and therapeutic purposes, The Cancer Genome Atlas (TCGA) provided a molecular classification of gastric cancers (GCs). Previous studies have used immunohistochemistry (IHC) and chromogenic in situ hybridization (CISH) to define immunophenotypic surrogate markers of the molecular alterations. Some critical issues concerning the correct definition of immunophenotypic groups have emerged in these studies that employed tissue microarrays (TMAs). We performed...
OCL : Last 20 articles
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White matter characteristics of motor, sensory and interhemispheric tracts underlying impaired upper limb function in children with unilateral cerebral palsy
Abstract This study explored the role of lesion timing (periventricular white matter versus cortical and deep grey matter lesions) and type of corticospinal tract (CST) wiring pattern (contralateral, bilateral, ipsilateral) on white matter characteristics of the CST, medial lemniscus, superior thalamic radiations and sensorimotor transcallosal fibers in children with unilateral cerebral palsy (CP), and examined the association with upper limb function. Thirty-four children (mean...
Latest Results for Brain Structure and Function
18h
Endo-Paro-Läsionen – Diagnostik und Therapieoptionen
Zusammenfassung Endo-Paro-Läsionen sind Erkrankungen, die sowohl das Parodontium als auch das Endodontium betreffen und sich wechselweise bedingen können. Dabei handelt es sich meist um eine Infektionsausbreitung vom Wurzelkanalsystem zum Parodontium oder in selteneren Fällen umgekehrt. Entscheidend für die Prognose sind die richtige Diagnose sowie eine adäquate Therapie, die insbesondere die korrekte Behandlungsabfolge berücksichtigt. Dieser Beitrag beschreibt die Diagnostik und...
Latest Results for Der MKG-Chirurg
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Kinin B1 receptor: a potential therapeutic target in sepsis-induced vascular hyperpermeability
In sepsis, the endothelial barrier becomes incompetent, with the leaking of plasma into interstitial tissues. VE-cadherin, an adherens junction protein, is the gatekeeper of endothelial cohesion. Kinins, relea...
Journal of Translational Medicine - Latest Articles
18h
Altered muscle membrane potential and redox status differentiates two subgroups of patients with chronic fatigue syndrome
In myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), altered membrane excitability often occurs in exercising muscles demonstrating muscle dysfunction regardless of any psychiatric disorder. Increas...
Journal of Translational Medicine - Latest Articles
18h
Characterization of IL-19, -20, and -24 in acute and chronic kidney diseases reveals a pro-fibrotic role of IL-24
Recently, the role of IL-19, IL-20 and IL-24 has been reported in renal disorders. However, still little is known about their biological role.
Journal of Translational Medicine - Latest Articles
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JPM, Vol. 10, Pages 27: Opioid Induced Hyperalgesia, a Research Phenomenon or a Clinical Reality? Results of a Canadian Survey
JPM, Vol. 10, Pages 27: Opioid Induced Hyperalgesia, a Research Phenomenon or a Clinical Reality? Results of a Canadian Survey Journal of Personalized Medicine doi: 10.3390/jpm10020027 Authors: Vargas-Schaffer Paquet Neron Cogan Background: Very little is known regarding the prevalence of opioid induced hyperalgesia (OIH) in day to day medical practice. The aim of this study was to evaluate the physician&rsquo;s perception of the prevalence of OIH within their practice,...
Journal of Personalized Medicine
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Idioms, collocations, and structure
Abstract Phrasal idioms have been used as evidence in syntactic theorizing for decades. A common assumption, occasionally made explicit (e.g., Larson 2017), is that non-literal phrasal idioms differ significantly from completely literal collocations in the kinds of syntactic structures they can be built from. I show with a detailed empirical study that this is false. In fact, the syntactic constraints on idioms and collocations are identical. In particular, patterns that are...
Latest Results for Natural Language
18h
Short-Term Change in Measures of Glycemia in Obese Youth Meeting Criteria for Prediabetes: A Retrospective Chart Review
Background: The prevalence of youth diagnosed with prediabetes is increasing, yet there is a lack of guidelines on how to manage this condition clinically. Objectives: The aim was to determine the short-term outcomes of patients referred with prediabetes and to determine predictors of worsening dysglycemia in youth. Study Design: This is a retrospective chart review of patients referred to our Youth Diabetes Prevention Clinic (YDPC) with laboratory tests indicating an increased risk for type 2 diabetes...
HRP : Last 20 articles
18h
Older people and death-thought accessibility: The association between death and older people in memory
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Death Studies: Table of Contents: Taylor and Francis
18h
PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells
Publication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Elizabeth Foxall, Adela Staszowska, Liisa M. Hirvonen, Mirella Georgouli, Mariacristina Ciccioli, Alexander Rimmer, Lynn Williams, Yolanda Calle, Victoria Sanz-Moreno, Susan Cox, Gareth E. Jones, Claire M. Wells
ScienceDirect Publication: Cell Reports
18h
CytoMAP: A Spatial Analysis Toolbox Reveals Features of Myeloid Cell Organization in Lymphoid Tissues
Publication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Caleb R. Stoltzfus, Jakub Filipek, Benjamin H. Gern, Brandy E. Olin, Joseph M. Leal, Yajun Wu, Miranda R. Lyons-Cohen, Jessica Y. Huang, Clarissa L. Paz-Stoltzfus, Courtney R. Plumlee, Thomas Pöschinger, Kevin B. Urdahl, Mario Perro, Michael Y. Gerner
ScienceDirect Publication: Cell Reports
18h
Genome-wide Profiling Identifies DNA Methylation Signatures of Aging in Rod Photoreceptors Associated with Alterations in Energy Metabolism
Publication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Ximena Corso-Díaz, James Gentry, Ryan Rebernick, Catherine Jaeger, Matthew J. Brooks, Freekje van Asten, Keshav Kooragayala, Linn Gieser, Jacob Nellissery, Raul Covian, Tiziana Cogliati, Anupam K. Mondal, Ke Jiang, Anand Swaroop
ScienceDirect Publication: Cell Reports
18h
IL-33-PU.1 Transcriptome Reprogramming Drives Functional State Transition and Clearance Activity of Microglia in Alzheimer’s Disease
Publication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Shun-Fat Lau, Congping Chen, Wing-Yu Fu, Jianan Y. Qu, Tom H. Cheung, Amy K.Y. Fu, Nancy Y. Ip
ScienceDirect Publication: Cell Reports
18h
Dopaminergic Control of Striatal Cholinergic Interneurons Underlies Cocaine-Induced Psychostimulation
Publication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Robert G. Lewis, Marcello Serra, Daniela Radl, Michela Gori, Catherine Tran, Sharon E. Michalak, Christopher D. Vanderwal, Emiliana Borrelli
ScienceDirect Publication: Cell Reports
18h
VMHvl-Projecting <em>Vglut1</em><strong>+</strong> Neurons in the Posterior Amygdala Gate Territorial Aggression
Publication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Xi Zha, Lei Wang, Zhuo-Lei Jiao, Rong-Rong Yang, Chun Xu, Xiao-Hong Xu
ScienceDirect Publication: Cell Reports
18h
16p11 Duplication Disrupts Hippocampal-Orbitofrontal-Amygdala Connectivity, Revealing a Neural Circuit Endophenotype for Schizophrenia
Publication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Greg C. Bristow, David M. Thomson, Rebecca L. Openshaw, Emma J. Mitchell, Judith A. Pratt, Neil Dawson, Brian J. Morris
ScienceDirect Publication: Cell Reports
18h
Imbalance of Excitatory/Inhibitory Neuron Differentiation in Neurodevelopmental Disorders with an <em>NR2F1</em> Point Mutation
Publication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Ke Zhang, Fang Yu, Jian Zhu, Sue Han, Jiehui Chen, Xuanyuan Wu, Yingying Chen, Tingyu Shen, Jiaoyang Liao, Wenke Guo, Xianfa Yang, Ran Wang, Yun Qian, Jiaxin Yang, Leping Cheng, Yun Zhao, Chi-Chung Hui, Jinsong Li, Guangdun Peng, Shuijin He
ScienceDirect Publication: Cell Reports
18h
Knocking Out Non-muscle Myosin II in Retinal Ganglion Cells Promotes Long-Distance Optic Nerve Regeneration
Publication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Xue-Wei Wang, Shu-Guang Yang, Chi Zhang, Ming-Wen Hu, Jiang Qian, Jin-Jin Ma, Yingchi Zhang, Bin-Bin Yang, Yi-Lan Weng, Guo-Li Ming, Anish R. Kosanam, Saijilafu, Feng-Quan Zhou
ScienceDirect Publication: Cell Reports
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Wdr47 Controls Neuronal Polarization through the Camsap Family Microtubule Minus-End-Binding Proteins
Publication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Yawen Chen, Jianqun Zheng, Xiaowei Li, Lei Zhu, Zhifeng Shao, Xiumin Yan, Xueliang Zhu
ScienceDirect Publication: Cell Reports
18h
m.3243A > G-Induced Mitochondrial Dysfunction Impairs Human Neuronal Development and Reduces Neuronal Network Activity and Synchronicity
Publication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Teun M. Klein Gunnewiek, Eline J.H. Van Hugte, Monica Frega, Gemma Solé Guardia, Katharina Foreman, Daan Panneman, Britt Mossink, Katrin Linda, Jason M. Keller, Dirk Schubert, David Cassiman, Richard Rodenburg, Noemi Vidal Folch, Devin Oglesbee, Ester Perales-Clemente, Timothy J. Nelson, Eva Morava, Nael Nadif Kasri, Tamas Kozicz
ScienceDirect Publication: Cell Reports
18h
Dissecting the Roles of Mitochondrial Complex I Intermediate Assembly Complex Factors in the Biogenesis of Complex I
Publication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Luke E. Formosa, Linden Muellner-Wong, Boris Reljic, Alice J. Sharpe, Thomas D. Jackson, Traude H. Beilharz, Diana Stojanovski, Michael Lazarou, David A. Stroud, Michael T. Ryan
ScienceDirect Publication: Cell Reports
18h
Rational Design of Allosteric and Selective Inhibitors of the Molecular Chaperone TRAP1
Publication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Carlos Sanchez-Martin, Elisabetta Moroni, Mariarosaria Ferraro, Claudio Laquatra, Giuseppe Cannino, Ionica Masgras, Alessandro Negro, Paolo Quadrelli, Andrea Rasola, Giorgio Colombo
ScienceDirect Publication: Cell Reports
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A Steric “Ball-and-Chain” Mechanism for pH-Mediated Regulation of Gap Junction Channels
Publication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Ali K. Khan, Maciej Jagielnicki, William E. McIntire, Michael D. Purdy, Venkatasubramanian Dharmarajan, Patrick R. Griffin, Mark Yeager
ScienceDirect Publication: Cell Reports
18h
The Asymmetric Expression of <em>SAUR</em> Genes Mediated by ARF7/19 Promotes the Gravitropism and Phototropism of Plant Hypocotyls
Publication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Xiaoyi Wang, Renbo Yu, Jiajun Wang, Zechuan Lin, Xue Han, Zhaoguo Deng, Liumin Fan, Hang He, Xing Wang Deng, Haodong Chen
ScienceDirect Publication: Cell Reports
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Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase
Publication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Andrés Bueno Venegas, Toyoaki Natsume, Masato Kanemaki, Ian D. Hickson
ScienceDirect Publication: Cell Reports
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Super-Enhancer Redistribution as a Mechanism of Broad Gene Dysregulation in Repeatedly Drug-Treated Cancer Cells
Publication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Qi Ma, Feng Yang, Carlos Mackintosh, Ranveer Singh Jayani, Soohwan Oh, Chunyu Jin, Sreejith Janardhanan Nair, Daria Merkurjev, Wubin Ma, Stephanie Allen, Dong Wang, Angels Almenar-Queralt, Ivan Garcia-Bassets
ScienceDirect Publication: Cell Reports
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The YEATS Domain Histone Crotonylation Readers Control Virulence-Related Biology of a Major Human Pathogen
Publication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Qi Wang, Jiyoti Verma, Nikolina Vidan, Yanan Wang, Timothy M. Tucey, Tricia L. Lo, Paul F. Harrison, Michael See, Angavai Swaminathan, Karl Kuchler, Michael Tscherner, Jiangning Song, David R. Powell, Mary Sopta, Traude H. Beilharz, Ana Traven
ScienceDirect Publication: Cell Reports
18h
Pan-retroviral Nucleocapsid-Mediated Phase Separation Regulates Genomic RNA Positioning and Trafficking
Publication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Anne Monette, Meijuan Niu, Lois Chen, Shringar Rao, Robert James Gorelick, Andrew John Mouland
ScienceDirect Publication: Cell Reports
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Cellular Importin-α3 Expression Dynamics in the Lung Regulate Antiviral Response Pathways against Influenza A Virus Infection
Publication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Swantje Thiele, Stephanie Stanelle-Bertram, Sebastian Beck, Nancy Mounogou Kouassi, Martin Zickler, Martin Müller, Berfin Tuku, Patricia Resa-Infante, Debby van Riel, Malik Alawi, Thomas Günther, Franziska Rother, Stefanie Hügel, Susanne Reimering, Alice McHardy, Adam Grundhoff, Wolfram Brune, Albert Osterhaus, Michael Bader, Enno Hartmann
ScienceDirect Publication: Cell Reports
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The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by β-Glucan
Publication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Samuel T. Keating, Laszlo Groh, Charlotte D.C.C. van der Heijden, Hanah Rodriguez, Jéssica C. dos Santos, Stephanie Fanucchi, Jun Okabe, Harikrishnan Kaipananickal, Jelmer H. van Puffelen, Leonie Helder, Marlies P. Noz, Vasiliki Matzaraki, Yang Li, L. Charlotte J. de Bree, Valerie A.C.M. Koeken, Simone J.C.F.M. Moorlag, Vera P. Mourits, Jorge Domínguez-Andrés, Marije Oosting, Elianne P. Bulthuis
ScienceDirect Publication: Cell Reports
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