IJMS, Vol. 21, Pages 2742: Molecular Mechanisms, Diagnostic Aspects and Therapeutic Opportunities of Micro Ribonucleic Acids in Atrial Fibrillation International Journal of Molecular Sciences doi: 10.3390/ijms21082742 Authors: Allan Böhm Marianna Vachalcova Peter Snopek Ljuba Bacharova Dominika Komarova Robert Hatala Micro ribonucleic acids (miRNAs) are short non-coding RNA molecules responsible for regulation of gene expression. They are involved in many pathophysiological...
IJMS, Vol. 21, Pages 2741: HIV-1 and Amyloid Beta Remodel Proteome of Brain Endothelial Extracellular Vesicles International Journal of Molecular Sciences doi: 10.3390/ijms21082741 Authors: Ibolya E. András Brice B. Sewell Michal Toborek Amyloid beta (Aβ) depositions are more abundant in HIV-infected brains. The blood–brain barrier, with its backbone created by endothelial cells, is assumed to be a core player in Aβ homeostasis and may contribute to...
IJMS, Vol. 21, Pages 2723: Heterogenic Origin of Micro RNAs in Atlantic Salmon (Salmo salar) Seminal Plasma International Journal of Molecular Sciences doi: 10.3390/ijms21082723 Authors: Teshome Tilahun Bizuayehu Igor Babiak The origin and contribution of seminal plasma RNAs into the whole semen RNA repertoire are poorly known, frequently being overlooked or neglected. In this study, we used high-throughput sequencing and RT-qPCR to profile microRNA (miRNA) constituents in the whole...
IJMS, Vol. 21, Pages 2738: Chemical Defoliant Promotes Leaf Abscission by Altering ROS Metabolism and Photosynthetic Efficiency in Gossypium hirsutum International Journal of Molecular Sciences doi: 10.3390/ijms21082738 Authors: Dingsha Jin Xiangru Wang Yanchao Xu Huiping Gui Hengheng Zhang Qiang Dong Ripon Kumar Sikder Guozheng Yang Meizhen Song Chemical defoliation is an important part of cotton mechanical harvesting, which can effectively reduce the impurity...
IJMS, Vol. 21, Pages 2739: In Vivo Targets of Pasteurella Multocida Toxin International Journal of Molecular Sciences doi: 10.3390/ijms21082739 Authors: Arshiya Banu Alistair J. Lax Agamemnon E. Grigoriadis Many Pasteurella multocida strains are carried as commensals, while some cause disease in animals and humans. Some type D strains cause atrophic rhinitis in pigs, where the causative agent is known to be the Pasteurella multocida toxin (PMT). PMT activates three families of...
IJMS, Vol. 21, Pages 2737: Molecular Mechanisms of Brassinosteroid-Mediated Responses to Changing Environments in Arabidopsis International Journal of Molecular Sciences doi: 10.3390/ijms21082737 Authors: Minghui Lv Jia Li Plant adaptations to changing environments rely on integrating external stimuli into internal responses. Brassinosteroids (BRs), a group of growth-promoting phytohormones, have been reported to act as signal molecules mediating these processes. BRs are perceived...
IJMS, Vol. 21, Pages 2732: Effects of Single and Double Mutants in Human Glucose-6-Phosphate Dehydrogenase Variants Present in the Mexican Population: Biochemical and Structural Analysis International Journal of Molecular Sciences doi: 10.3390/ijms21082732 Authors: Víctor Martínez-Rosas Merit Valeria Juárez-Cruz Edson Jiovany Ramírez-Nava Beatriz Hernández-Ochoa Laura Morales-Luna Abigail González-Valdez Hugo Serrano-Posada Noemí Cárdenas-Rodríguez Paulina Ortiz-Ramírez...
IJMS, Vol. 21, Pages 2736: Caspase-11 Non-Canonical Inflammasome: Emerging Activator and Regulator of Infection-Mediated Inflammatory Responses International Journal of Molecular Sciences doi: 10.3390/ijms21082736 Authors: Young-Su Yi Inflammation is a body’s protective mechanism to eliminate invading pathogens and cellular damaging signals. The inflammatory response consists of two main consecutive steps—a priming step preparing the inflammatory responses and a triggering step boosting...
IJMS, Vol. 21, Pages 2729: Pro-Apoptotic Function Analysis of the Reaper Homologue IBM1 in Spodoptera frugiperda International Journal of Molecular Sciences doi: 10.3390/ijms21082729 Authors: Benshui Shu Jingjing Zhang Sethuraman Veeran Guohua Zhong As an important type of programmed cell death, apoptosis plays a critical role in lepidopteran insects in response to various internal and external stresses. It is controlled by a network of genes such as those encoding the inhibitor...
IJMS, Vol. 21, Pages 2735: TGF-β Signaling Regulates SLC8A3 Expression and Prevents Oxidative Stress in Developing Midbrain Dopaminergic and Dorsal Raphe Serotonergic Neurons International Journal of Molecular Sciences doi: 10.3390/ijms21082735 Authors: Enaam Chleilat Abhishek Pethe Dietmar Pfeifer Kerstin Krieglstein Eleni Roussa Calcium homeostasis is a cellular process required for proper cell function and survival, maintained by the coordinated action of several transporters,...
IJMS, Vol. 21, Pages 2733: The Important Function of Mediator Complex in Controlling the Developmental Transitions in Plants International Journal of Molecular Sciences doi: 10.3390/ijms21082733 Authors: Lingjie Zhang Changkui Guo Developmental transitions in plants are tightly associated with changes in the transcriptional regulation of gene expression. One of the most important regulations is conferred by cofactors of RNA polymerase II including the mediator complex, a large complex...
IJMS, Vol. 21, Pages 2730: Comparative Analysis of Functional and Structural Decline in Retinitis Pigmentosas International Journal of Molecular Sciences doi: 10.3390/ijms21082730 Authors: Thiago Cabral Jose Ronaldo Lima de Carvalho Joonpyo Kim Jin Kyun Oh Sarah R. Levi Karen Sophia Park Jimmy K. Duong Junhyung Park Katherine Boudreault Rubens Belfort Stephen H. Tsang Retinitis pigmentosa (RP) is a category of inherited retinal dystrophies that is best prognosticated...
IJMS, Vol. 21, Pages 2728: Report of the 23rd Meeting on Signal Transduction 2019—Trends in Cancer and Infection International Journal of Molecular Sciences doi: 10.3390/ijms21082728 Authors: Bastian Schirmer Klaudia Giehl Katharina F. Kubatzky The annual meeting “Signal Transduction–Receptors, Mediators and Genes” of the Signal Transduction Society (STS) is an interdisciplinary conference open to all scientists sharing the common interest in elucidating...
IJMS, Vol. 21, Pages 2731: Plant Cell Wall Proteins and Development International Journal of Molecular Sciences doi: 10.3390/ijms21082731 Authors: Elisabeth Jamet Christophe Dunand Plant cell walls surround cells and provide both external protection and a means of cell-to-cell communication [...]
IJMS, Vol. 21, Pages 2727: Carbohydrate-Active Enzymes: Structure, Activity, and Reaction Products International Journal of Molecular Sciences doi: 10.3390/ijms21082727 Authors: Stefano Benini Carbohydrate-active enzymes are responsible for both the biosynthesis and breakdown of carbohydrates and glycoconjugates [...]
IJMS, Vol. 21, Pages 2725: Changes in the Cellular Distribution of Tyrosine Phosphorylation and Its Relationship with the Acrosomal Exocytosis and Plasma Membrane Integrity during In Vitro Capacitation of Frozen/Thawed Bull Spermatozoa International Journal of Molecular Sciences doi: 10.3390/ijms21082725 Authors: Sara Ruiz-Díaz Sergio Grande-Pérez Sol Arce-López Carolina Tamargo Carlos Olegario Hidalgo Serafín Pérez-Cerezales During sperm capacitation, intracellular signaling...
IJMS, Vol. 21, Pages 2724: Single-Cell Gene Profiling Reveals Social Status-Dependent Modulation of Nuclear Hormone Receptors in GnRH Neurons in a Male Cichlid Fish International Journal of Molecular Sciences doi: 10.3390/ijms21082724 Authors: Satoshi Ogawa Ishwar S. Parhar Gonadotropin-releasing hormone (GnRH) is essential for the initiation and maintenance of reproductive functions in vertebrates. To date, three distinct paralogue lineages, GnRH1, GnRH2, and GnRH3, have been identified...
IJMS, Vol. 21, Pages 2726: Dextran Sodium Sulfate-Induced Impairment of Protein Trafficking and Alterations in Membrane Composition in Intestinal Caco-2 Cell Line International Journal of Molecular Sciences doi: 10.3390/ijms21082726 Authors: Mohamad Toutounji Dalanda Wanes Mohammad El-Harakeh Marwan El-Sabban Sandra Rizk Hassan Y. Naim A key morphological feature of inflammatory bowel disease (IBD) is the loss of the barrier function of intestinal epithelial cells. The...
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JCM, Vol. 9, Pages 1131: Pharmacological Therapeutics Targeting RNA-Dependent RNA Polymerase, Proteinase and Spike Protein: From Mechanistic Studies to Clinical Trials for COVID-19 Journal of Clinical Medicine doi: 10.3390/jcm9041131 Authors: Jiansheng Huang Wenliang Song Hui Huang Quancai Sun An outbreak of novel coronavirus-related pneumonia COVID-19, that was identified in December 2019, has expanded rapidly, with cases now confirmed in more than 211 countries or areas. This...
JCM, Vol. 9, Pages 1129: Neoadjuvant Therapy for Resectable and Borderline Resectable Pancreatic Cancer: A Meta-Analysis of Randomized Controlled Trials Journal of Clinical Medicine doi: 10.3390/jcm9041129 Authors: Jordan M. Cloyd Victor Heh Timothy M. Pawlik Aslam Ejaz Mary Dillhoff Allan Tsung Terence Williams Laith Abushahin John F. P. Bridges Heena Santry The efficacy of neoadjuvant therapy (NT) versus surgery first (SF) for pancreatic ductal adenocarcinoma...
JCM, Vol. 9, Pages 1136: Lactate and BDNF: Key Mediators of Exercise Induced Neuroplasticity? Journal of Clinical Medicine doi: 10.3390/jcm9041136 Authors: Müller Duderstadt Lessmann Müller Accumulating evidence from animal and human studies supports the notion that physical exercise can enhance neuroplasticity and thus reduce the risk of several neurodegenerative diseases (e.g., dementia). However, the underlying neurobiological mechanisms of exercise induced neuroplasticity...
JCM, Vol. 9, Pages 1135: The Anatomy of the Tibial Nutrient Artery Canal—An Investigation of 106 Patients Using Multi-Detector Computed Tomography Journal of Clinical Medicine doi: 10.3390/jcm9041135 Authors: Almansour Armoutsis Reumann Nikolaou Springer Radiologic evaluation of the tibial nutrient artery is clinically important as disruption of tibial blood supply is a risk factor for delayed or non-union of tibial fractures. Damage to the tibial nutrient artery canal...
JCM, Vol. 9, Pages 1128: Prognostic Value of Neutrophil-To-Lymphocyte Ratio and Platelet-To-Lymphocyte Ratio for Renal Outcomes in Patients with Rapidly Progressive Glomerulonephritis Journal of Clinical Medicine doi: 10.3390/jcm9041128 Authors: Yukari Mae Tomoaki Takata Ayami Ida Masaya Ogawa Sosuke Taniguchi Marie Yamamoto Takuji Iyama Satoko Fukuda Hajime Isomoto Background: Rapidly progressive glomerulonephritis (RPGN) is a syndrome characterized by a rapid...
JCM, Vol. 9, Pages 1130: Expression of the Novel Cardiac Biomarkers sST2, GDF-15, suPAR, and H-FABP in HFpEF Patients Compared to ICM, DCM, and Controls Journal of Clinical Medicine doi: 10.3390/jcm9041130 Authors: Peter Jirak Rudin Pistulli Michael Lichtenauer Bernhard Wernly Vera Paar Lukas J. Motloch Richard Rezar Christian Jung Uta C. Hoppe P. Christian Schulze Daniel Kretzschmar Rüdiger C. Braun-Dullaeus Tarek Bekfani Background: Heart failure...
JCM, Vol. 9, Pages 1132: Velocity Vector Imaging Assessment of Functional Change in the Right Ventricle during Transcatheter Closure of Atrial Septal Defect by Intracardiac Echocardiography Journal of Clinical Medicine doi: 10.3390/jcm9041132 Authors: Se Yong Jung Jae Il Shin Jae Young Choi Su-Jin Park Nam Kyun Kim The functional change of the right ventricle (RV) after atrial septal defect (ASD) via transcatheter closure is well known. We assessed the immediate RV functional...
JCM, Vol. 9, Pages 1127: Combining Dynamic Hyperinflation with Dead Space Volume during Maximal Exercise in Patients with Chronic Obstructive Pulmonary Disease Journal of Clinical Medicine doi: 10.3390/jcm9041127 Authors: Ming-Lung Chuang Physiological dead space volume (VD) and dynamic hyperinflation (DH) are two different types of abnormal pulmonary physiology. Although they both involve lung volume, their combination has never been advocated, and thus their effect and implication...
JCM, Vol. 9, Pages 1133: Delta Neutrophil Index for the Prediction of Prognosis in Acute Gastrointestinal Diseases; Diagnostic Test Accuracy Meta-Analysis Journal of Clinical Medicine doi: 10.3390/jcm9041133 Authors: Jeong Bang Lee Baik Delta neutrophil index (DNI) is a novel diagnostic and prognostic biomarker of various infectious or inflammatory conditions. However, data on optimal measurement time are scarce, and no studies have evaluated the potential role of the DNI...
JCM, Vol. 9, Pages 1134: Usefulness of P Wave Duration in Embolic Stroke of Undetermined Source Journal of Clinical Medicine doi: 10.3390/jcm9041134 Authors: Moonki Jung Jin-Seok Kim Ju Hyeon Song Jeong-Min Kim Kwang-Yeol Park Wang-Soo Lee Sang Wook Kim Gregory YH Lip Seung Yong Shin The investigation of the potential association between ischemic stroke and subclinical atrial fibrillation (SCAF) is important for secondary prevention. We aimed to determine whether...
JCM, Vol. 9, Pages 1126: COVID-19: A Recommendation to Examine the Effect of Mouthrinses with β-Cyclodextrin Combined with Citrox in Preventing Infection and Progression. Journal of Clinical Medicine doi: 10.3390/jcm9041126 Authors: Carrouel Conte Fisher Gonçalves Dussart Llodra Bourgeois Considered to be a major portal of entry for infectious agents, the oral cavity is directly associated with the evolutionary process of SARS‐CoV‐2 in its inhalation of ambient...
JCM, Vol. 9, Pages 1124: Marfan Syndrome Versus Bicuspid Aortic Valve Disease: Comparative Analysis of Obstetric Outcome and Pregnancy-Associated Immediate and Long-Term Aortic Complications Journal of Clinical Medicine doi: 10.3390/jcm9041124 Authors: Betül Toprak Katalin Szöcs Elvin Zengin-Sahm Christoph Sinning Amra Hot Peter Bannas Kurt Hecher Bernd Hüneke Thomas S. Mir Meike Rybczynski Evaldas Girdauskas Stefan Blankenberg Yskert von Kodolitsch ...
JCM, Vol. 9, Pages 1125: Predicting Stroke Outcomes Using Ankle-Brachial Index and Inter-Ankle Blood Pressure Difference Journal of Clinical Medicine doi: 10.3390/jcm9041125 Authors: Minho Han Young Dae Kim Jin Kyo Choi Junghye Choi Jimin Ha Eunjeong Park Jinkwon Kim Tae-Jin Song Ji Hoe Heo Hyo Suk Nam Background: This study investigated the association of high ankle-brachial index difference (ABID) and systolic inter-ankle blood pressure difference (IAND)...
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Medicina, Vol. 56, Pages 182: Predictors of Cardiovascular Events in Hypertensive Patients with High Cardiovascular Risk Medicina doi: 10.3390/medicina56040182 Authors: Ivan Tasić Svetlana Kostić Nikola M. Stojanović Dragan Djordjević Dragan Bogdanović Marina Deljanin Ilić Milan Lović Viktor Stoičkov Srdjan Aleksandrić Background and objectives: A long-term therapeutic strategy in hypertensive patients equally depends on measured arterial blood pressure values...
Medicina, Vol. 56, Pages 180: Non-Clinical Variables Influencing Cesarean Section Rate According to Robson Classification Medicina doi: 10.3390/medicina56040180 Authors: Noemi Strambi Flavia Sorbi Gian Marco Bartolini Chiara Forconi Giovanni Sisti Viola Seravalli Mariarosaria Di Tommaso Background and Objectives: The incidence of cesarean section (CS) has progressively increased worldwide, without any proven benefit to either the mother or the newborn. The aim of this...
Medicina, Vol. 56, Pages 181: Community Pharmacists’ Knowledge, Attitude, and Practice in Providing Self-Care Recommendations for the Management of Premenstrual Syndrome Medicina doi: 10.3390/medicina56040181 Authors: Muhammad Taufik Suaidi Poh Kuan Wong Nurul Ain Mohd Tahir Eng Wee Chua Background and objectives: Premenstrual syndrome (PMS) comprises a variety of physical and emotional symptoms that affect women of reproductive age. The distress caused by PMS often leads to...
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Membranes, Vol. 10, Pages 70: Mesoporous Silica Membranes Silylated by Fluorinated and Non-Fluorinated Alkylsilanes for the Separation of Methyl Tert-Butyl Ether from Water Membranes doi: 10.3390/membranes10040070 Authors: Zhaojia Wang Liwei Hao Feihua Yang Qi Wei It is of great significance to separate hazardous methyl tert-butyl ether (MTBE) from water in terms of environmental protection and human health. In the present work, α-Al2O3-suppotred silica membranes were...
Membranes, Vol. 10, Pages 71: Structural, Morphological, Electrical and Electrochemical Properties of PVA: CS-Based Proton-Conducting Polymer Blend Electrolytes Membranes doi: 10.3390/membranes10040071 Authors: Shahab Marf Abdullah Aziz Polymer blend electrolytes based on poly(vinyl alcohol):chitosan (PVA:CS) incorporated with various quantities of ammonium iodide were prepared and characterized using a range of electrochemical, structural and microscopic techniques. In the...
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Microorganisms, Vol. 8, Pages 572: Resistome, Mobilome and Virulome Analysis of Shewanella algae and Vibrio spp. Strains Isolated in Italian Aquaculture Centers Microorganisms doi: 10.3390/microorganisms8040572 Authors: Vanessa Zago Laura Veschetti Cristina Patuzzo Giovanni Malerba Maria M. Lleo Antimicrobial resistance is a major public health concern restricted not only to healthcare settings but also to veterinary and environmental ones. In this study, we analyzed, by...
Microorganisms, Vol. 8, Pages 574: Sugar Alcohols and Organic Acids Synthesis in Yarrowia lipolytica: Where Are We? Microorganisms doi: 10.3390/microorganisms8040574 Authors: Fickers Cheng Sze Ki Lin Sugar alcohols and organic acids that derive from the metabolism of certain microorganisms have a panoply of applications in agro-food, chemical and pharmaceutical industries. The main challenge in their production is to reach a productivity threshold that allow the process to be...
Microorganisms, Vol. 8, Pages 568: The Aquatic Ecosystem, a Good Environment for the Horizontal Transfer of Antimicrobial Resistance and Virulence-Associated Factors Among Extended Spectrum β-lactamases Producing E. coli Microorganisms doi: 10.3390/microorganisms8040568 Authors: Lara Pérez-Etayo David González Ana Isabel Vitas One of the main public health problems nowadays is the increase of antimicrobial resistance, both in the hospital environment and outside it (animal environment,...
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