Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης: M

SAGE Publications Inc: Technology in Cancer Research & Treatment: Table of Contents

Atlas Sampling for Prone Breast Automatic Segmentation of Organs at Risk: The Importance of Patients’ Body Mass Index and Breast Cup Size for an Optimized Contouring of the Heart and the Coronary Vessels

Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Objective:Delineation of organs at risk is a time-consuming task. This study evaluates the benefits of using single-subject atlas-based automatic segmentation of organs at risk in patients with breast cancer treated in prone position, with 2 different criteria for choosing the atlas subject. Together with laterality (left/right), the criteria used were either (1) breast volume or (2) body mass index and breast...

SAGE Publications Inc: Technology in Cancer Research & Treatment: Table of Contents

Tue Apr 21, 2020 13:27

Robust Optimization of SBRT Planning for Patients With Early Stage Non-Small Cell Lung Cancer

Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Purpose:Setup uncertainty is a known challenge for stereotactic body radiotherapy planning. Using the internal target volume-based robust optimization was proposed as a more accurate way than the conventional planning target volume-based optimization when considering the robustness criteria. In this study, we aim to investigate the feasibility of internal target volume-based robust optimization in stereotactic...

SAGE Publications Inc: Technology in Cancer Research & Treatment: Table of Contents

Tue Apr 21, 2020 13:25

MiR-203a-3p Inhibits Pancreatic Cancer Cell Proliferation, EMT, and Apoptosis by Regulating SLUG

Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Objective:The aim of the present research is to study the roles of miR-203a-3p on cell proliferation, migration, invasion, and epithelial–mesenchymal transition in pancreatic cancer.Methods:Transcription profiles were acquired from Gene Expression Omnibus database, which was used to screen out the differentially expressed microRNAs and messenger RNAs in pancreatic cancer. Pancreatic cancer tissues were used to...

SAGE Publications Inc: Technology in Cancer Research & Treatment: Table of Contents

Fri Apr 17, 2020 12:32

Knockdown of Rab9 Suppresses the Progression of Gastric Cancer Through Regulation of Akt Signaling Pathway

Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Rabs have been reported to be involved in the carcinogenesis process and in the progression of cancer. However, it is unclear whether or not Rab9 is associated with the development of cancer. In the present study, we aimed to investigate the role of Rab9 in the biological functions of gastric cancer cells. The gastric cancer cell lines AGS and MKN45 were transfected with siRNA-Rab9 to block the expression of Rab9....

SAGE Publications Inc: Technology in Cancer Research & Treatment: Table of Contents

Fri Apr 17, 2020 12:29

Circulating Tumor Cells and Fibronectin 1 in the Prognosis of Nasopharyngeal Carcinoma

Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Objective:Nasopharyngeal carcinoma is highly endemic in Southeast China. Circulating tumor cell is an important biomarker in the prognosis of variety kinds of cancers. Overexpression of fibronectin 1 was observed in variety kinds of malignancies and may contribute to progress and metastasis of the cancers. The current study was aimed to investigate phenotypes of circulating tumor cell in nasopharyngeal carcinoma...

SAGE Publications Inc: Technology in Cancer Research & Treatment: Table of Contents

Mon Apr 13, 2020 14:04

Inhibition of PTEN Gene Expression by Small Interfering RNA on PI3K/Akt/FoxO3a Signaling Pathway in Human Nasopharyngeal Carcinoma

Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. The objective of this article is to study the effect of inhibiting phosphatase and tensin homolog deleted chromatosome 10 gene on phosphoinositide 3-kinase/protein kinase B (Akt)/Forkhead homeobox O3a signaling pathway in human nasopharyngeal carcinoma HK-1 cells. Nasopharyngeal carcinoma HK-1 cell lines were divided into PTEN gene interference group (siPTEN), nonspecific small interfering RNA group (siNC), empty...

SAGE Publications Inc: Technology in Cancer Research & Treatment: Table of Contents

Mon Apr 13, 2020 13:03

MiR-19-3p Induces Tumor Cell Apoptosis via Targeting FAS in Rectal Cancer Cells

Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. MicroRNAs are reported as a vital important factor in cancer cell initiation and progression processes. MicroRNA-19-3p has drawn the attention of many researchers in recent years because of its wide expression and its key role in serious kinds of tumor cells. However, the detailed mechanism of microRNA-19a-3p in these tumors is still poorly understood. So, in the present study, we aimed to explore the biological...

SAGE Publications Inc: Technology in Cancer Research & Treatment: Table of Contents

Wed Apr 08, 2020 13:03

The Aberrant Expression of MicroRNA-125a-5p/IGF2BP3 Axis in Advanced Gastric Cancer and Its Clinical Relevance

Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. RNA-binding proteins have been associated with cancer development. The overexpression of a well-known RNA-binding protein, insulin-like growth factor 2 messenger RNA–binding protein 3, has been identified as an indicator of poor prognosis in patients with various types of cancer. Although gastric cancer is a relatively frequent and potentially fatal malignancy, the mechanism by which insulin-like growth factor...

SAGE Publications Inc: Technology in Cancer Research & Treatment: Table of Contents

Wed Apr 08, 2020 13:00

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Τρίτη 21 Απριλίου 2020

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