Related ArticlesComparison of GeneChip, nCounter and real-time polymerase chain reaction based gene expressions predicting loco-regional tumour control after primary and postoperative radiochemotherapy in head and neck squamous cell carcinoma. J Mol Diagn. 2020 Apr 02;: Authors: Schmidt S, Linge A, Großer M, Lohaus F, Gudziol V, Nowak A, Tinhofer I, Budach V, Sak A, Stuschke M, Balermpas P, Rödel C, Schäfer H, Grosu AL, Abdollahi A, Debus J, Ganswindt U, Belka C, Pigorsch...
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Related ArticlesAn alternative to skin graft for superficial surgical defect in oral cancer surgery. Braz J Otorhinolaryngol. 2020 Mar 11;: Authors: Tirelli G, Tofanelli M, Piccinato A, Boscolo Nata F Abstract INTRODUCTION: After surgery for oral cavity cancer, superficial surgical defects are usually covered with a skin graft that can be harvested with different thicknesses depending on the reconstructive need. Despite its popularity and efficacy,...
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Related ArticlesAdeno-associated virus gene replacement for recessive inner ear dysfunction: Progress and challenges. Hear Res. 2020 Mar 18;:107947 Authors: Askew C, Chien WW Abstract Approximately 3 in 1000 children in the US under 4 years of age are affected by hearing loss. Currently, cochlear implants represent the only line of treatment for patients with severe to profound hearing loss, and there are no targeted drug or biological based therapies...
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Related ArticlesMicronuclei and disease - Report of HUMN project workshop at Rennes 2019 EEMGS conference. Mutat Res. 2020 Feb - Mar;850-851:503133 Authors: Fenech M, Holland N, Kirsch-Volders M, Knudsen LE, Wagner KH, Stopper H, Knasmueller S, Bolognesi C, El-Zein R, Bonassi S Abstract The "Micronuclei and Disease" workshop was organized by the HUMN Project consortium and hosted by the European Environmental Mutagen and Genomics Society at their...
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Related ArticlesObturation and Tissue Transfer for Large Craniofacial Defects. Oral Maxillofac Surg Clin North Am. 2020 May;32(2):219-232 Authors: Schmidt CD, Patel SY, Woerner JE, Ghali GE Abstract Reconstruction of large craniofacial defects requires several factors to be considered before deciding on the best reconstructive option. This article discusses various factors taken into consideration when deciding on which reconstructive option is ideal...
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Related ArticlesPhenotypic profiling of mGlu7 knockout mice reveals new implications for neurodevelopmental disorders. Genes Brain Behav. 2020 Apr 04;: Authors: Fisher NM, Gould RW, Gogliotti RG, McDonald AJ, Badivuku H, Chennareddy S, Buch AB, Moore AM, Jenkins MT, Robb WH, Lindsley CW, Jones CK, Conn PJ, Niswender CM Abstract Neurodevelopmental disorders are characterized by deficits in communication, cognition, attention, social behavior and/or motor...
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Related ArticlesThree-dimensional analyses of short- and long-term effects of rapid maxillary expansion on nasal cavity and upper airway: a systematic review and meta-analysis. Orthod Craniofac Res. 2020 Apr 05;: Authors: Niu X, Di Carlo G, Cornelis MA, Cattaneo PM Abstract INTRODUCTION: The purpose of this systematic review was to evaluate the three-dimensional (3D) changes occurring at short- and long-term follow-up after rapid maxillary expansion...
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Related ArticlesChronic fatigue syndrome: progress and possibilities. Med J Aust. 2020 Apr 05;: Authors: Sandler CX, Lloyd AR Abstract Chronic fatigue syndrome (CFS) is a prevalent condition affecting about one in 100 patients attending primary care. There is no diagnostic test, validated biomarker, clear pathophysiology or curative treatment. The core symptom of fatigue affects both physical and cognitive activities, and features a prolonged post-activity...
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Related ArticlesPost-Traumatic Stress Disorder Symptoms Contribute to Worse Pain and Health Outcomes in Veterans With PTSD Compared to Those Without: A Systematic Review With Meta-Analysis. Mil Med. 2020 Apr 06;: Authors: Benedict TM, Keenan PG, Nitz AJ, Moeller-Bertram T Abstract INTRODUCTION: Post-traumatic stress disorder (PTSD) and chronic pain are frequently co-morbid conditions in the U.S. veteran population. Although several theories about the...
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Related ArticlesEmotional distress and quality of life in allergic diseases. Wiad Lek. 2020;73(2):370-373 Authors: Jarosz M, Syed S, Błachut M, Badura Brzoza K Abstract Emotional disorders accompany many somatic diseases, especially ones with severe or chronic course, and such are allergic diseases. Long-term course of the disease, the need for chronic treatment and repeated exacerbations as well as symptoms of depression or anxiety have a significant...
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Related ArticlesParent survey of sleep problems among children with CHARGE syndrome. Res Dev Disabil. 2020 Apr 02;101:103614 Authors: Kennert BA, Harshorne TS, Kanouse S, Johnson C Abstract Sleep problems are common among children, especially those with developmental disabilities, visual impairments, and behavioral problems. Past research has indicated a particularly high prevalence of clinically-relevant sleep problems for children with CHARGE syndrome,...
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Related ArticlesShort-term prognostic effects of circulating regulatory T-Cell suppressive function and vascular endothelial growth factor level in patients with non-small cell lung cancer and obstructive sleep apnea. Sleep Med. 2020 Feb 24;70:88-96 Authors: Liu Y, Lao M, Chen J, Lu M, Luo S, Ou Q, Luo Z, Yuan P, Chen J, Ye G, Gao X Abstract OBJECTIVE: To determine if suppressive function of regulatory T-cells (Tregs) and vascular endothelial cell growth...
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Related ArticlesEfficacy of continuous positive airway pressure (CPAP) in the prevention of cardiovascular events in patients with obstructive sleep apnea: Systematic review and meta-analysis. Sleep Med Rev. 2020 Mar 14;52:101312 Authors: Labarca G, Dreyse J, Drake L, Jorquera J, Barbe F Abstract Obstructive sleep apnea (OSA) commonly occurs in patients with increased cardiovascular (CV) risk, and continuous positive airway pressure (CPAP) is the preferred...
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Related ArticlesPrimary tracheocutaneous fistula closure with immediate transition to nocturnal noninvasive positive pressure ventilation in two children with Congenital Central Hypoventilation Syndrome. Int J Pediatr Otorhinolaryngol. 2020 Mar 24;134:110019 Authors: Kallenbach SL, Espahbodi M, Amos LB, Beste DJ, Chun RH Abstract Transitioning children with Congenital Central Hypoventilation Syndrome (CCHS) from nocturnal invasive ventilation via tracheostomy...
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Related ArticlesAlzheimer's disease beyond amyloid: can the repetitive failures of amyloid-targeted therapeutics inform future approaches to dementia drug discovery? Biochem Pharmacol. 2020 Apr 02;:113945 Authors: Mullane K, Williams M Abstract Alzheimer's Disease (AD) therapeutics based on the amyloid hypothesis have repeatedly failed in clinical trials. Together with numerous reports that amyloid is present in brains from aged individuals without cognitive...
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Related ArticlesMini-symposium: Sleep disordered breathing in children: Indications, interpretation and implications. Paediatr Respir Rev. 2020 Mar 04;: Authors: Fitzgerald DA PMID: 32247828 [PubMed - as supplied by publisher]
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Related ArticlesEustachian tube dysfunction in sleep apnea patients and improvements afforded by continuous positive airway pressure therapy. Braz J Otorhinolaryngol. 2020 Mar 12;: Authors: Cayir S, Hizli O, Kayabasi S, Yildirim G Abstract INTRODUCTION: Upper airway resistance may accompany eustachian dysfunction and alter middle ear pressure in patients with obstructive sleep apnea syndrome. OBJECTIVE: To investigate effects of obstructive...
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Related ArticlesFrequent restful sleep is associated with the absence of depressive symptoms and higher grade point average among college students. Sleep Health. 2020 Apr 01;: Authors: Rosso AC, Wilson OWA, Papalia Z, Duffey M, Kline CE, Bopp M Abstract OBJECTIVES: To examine how health behaviors and outcomes differ based on restful nights of sleep among college students. DESIGN: This is a cross-sectional study. SETTING: The study was...
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Related ArticlesUndiagnosed Obstructive Sleep Apnea May Significantly Impact Outcomes in Adults Admitted for COPD in an Inner-City Hospital. Chest. 2020 Apr 02;: Authors: Naranjo M, Willes L, Prillaman BA, Quan SF, Sharma S Abstract BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is the second most common cause of hospital admission in the United States. Obstructive sleep apnea (OSA) is a highly prevalent and underdiagnosed condition which may...
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Related ArticlesEmerging Concepts of the Pathophysiology and Adverse Outcomes of Restless Legs Syndrome. Chest. 2020 Apr 02;: Authors: Romero S, Cano-Pumarega I, García-Borreguero D Abstract Restless legs syndrome (RLS), also known as Willis-Ekbom disease (WED), is a common neurological disorder affecting up to 5-10% of the population, but it still remains an underdiagnosed condition. RLS/WED is characterized by uncomfortable sensations, mainly in the...
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Related ArticlesA feasibility study in the treatment of obstructive sleep apnea syndrome and snoring: Nasopharyngeal stent. Am J Otolaryngol. 2020 Mar 16;:102460 Authors: Yenigun A, Tugrul S, Dogan R, Aksoy F, Ozturan O Abstract OBJECTIVE: The objective of this study is to create a new choice of treatment with nasopharyngeal stent in isolated retro palatal obstruction and snoring for the treatment of obstructive sleep apnea syndrome (OSAS). ...
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Related ArticlesNocturnal cognitive arousal is associated with objective sleep disturbance and indicators of physiologic hyperarousal in good sleepers and individuals with insomnia disorder. Sleep Med. 2019 Nov 14;: Authors: Kalmbach DA, Buysse DJ, Cheng P, Roth T, Yang A, Drake CL Abstract BACKGROUND: Cognitive arousal is central to models of sleep disturbance and insomnia, but findings remain mixed regarding whether cognitive arousal is associated...
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Related ArticlesProdromal PD: A new nosological entity. Prog Brain Res. 2020;252:331-356 Authors: Schaeffer E, Postuma RB, Berg D Abstract Recent years have brought a rapid growth in knowledge of the prodromal phase of Parkinson's disease (PD). It is now clear that the clinical phase of PD is preceded by a phase of progressing neurodegeneration lasting many years. This involves not only central nervous system structures outside the substantia nigra and...
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Related ArticlesAssociation of Occupational Distress and Sleep-Related Impairment in Physicians With Unsolicited Patient Complaints. Mayo Clin Proc. 2020 Apr;95(4):719-726 Authors: Welle D, Trockel MT, Hamidi MS, Hickson GB, Menon NK, Shanafelt TD, Cooper WO Abstract OBJECTIVE: To study the relationship between occupational distress and sleep-related impairment in physicians and unsolicited patient complaints. PARTICIPANTS AND METHODS: We used...
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Related ArticlesSocial-emotional problems among Swedish three-year-olds: an Item Response Theory analysis of the Ages and Stages Questionnaires: Social-Emotional. BMC Pediatr. 2020 Apr 04;20(1):149 Authors: Vaezghasemi M, Eurenius E, Ivarsson A, Richter Sundberg L, Silfverdal SA, Lindkvist M Abstract BACKGROUND: There is enough evidence to believe that young children's social-emotional problems can have a long-term effect if extra support is not given...
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Related ArticlesThe Relationship between the Competence of Nurses and Their Attitudes in Medical Errors. J Nurs Manag. 2020 Apr 04;: Authors: Kirca N, Ozgonul ML, Bademli K Abstract AIM: The aim of this descriptive study is to determine the relationship between competencies and attitudes of nurses in medical errors. BACKGROUND: The level of competence of nurses directly affects the patient's safety, health status, morbidity and mortality rates,...
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Related ArticlesHospitalization length, surgical duration, and blood lost among the approaches for total hip arthroplasty: a Bayesian network meta-analysis. Musculoskelet Surg. 2020 Apr 04;: Authors: Migliorini F, Trivellas A, Eschweiler J, El Mansy Y, Mazzanti MC, Tingart M, Arentini P Abstract Despite the numerous studies, there is no consensus concerning the best approach for total hip arthroplasty (THA), and debates are ongoing. The purpose of this...
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Related ArticlesPrognostic significance of tumor poliovirus receptor and CTLA4 expression in patients with surgically resected non-small-cell lung cancer. J Cancer Res Clin Oncol. 2020 Apr 04;: Authors: You H, Zhang YZ, Lai HL, Li D, Liu YQ, Li RZ, Khan I, Hsiao WW, Duan FG, Fan XX, Yao XJ, Cao YB, Wu QB, Leung EL, Wang MF Abstract INTRODUCTION: Poliovirus receptor (PVR) is a tumor promoter and a regulatory checkpoint that enhances immunosuppression....
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Related Articles[Study protocol to improve the quality of delirium management in intensive care]. Med Klin Intensivmed Notfmed. 2020 Apr 04;: Authors: Mohammad B, Nydahl P, Borzikowsky C, Margraf NG, Studt S, Meyne J, Kott M, Panholzer B Abstract BACKGROUND: Delirium in cardiac surgery patients is common and is associated with prolonged mechanical ventilation and hospital stay as well as higher mortality. Protocols may improve outcome. In our cardiac...
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Related ArticlesHealthcare Consumption and Cost Estimates Concerning Swedish Women with Endometriosis. Gynecol Obstet Invest. 2020 Apr 03;:1-8 Authors: Grundström H, Hammar Spagnoli G, Lövqvist L, Olovsson M Abstract INTRODUCTION: Endometriosis is known for its substantial effect on women's wellbeing and quality of life. In order to evaluate disease burden, treatments and health services, assessments of healthcare consumption and cost estimates are necessary....
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Related ArticlesChoosing of drug for anesthesia in intensive therapy of traumatic disease for geriatric patients. Wiad Lek. 2020;73(2):312-315 Authors: Volkova YV, Sharlai KY, Boiko OV, Dmytriiev DV, Dmytriiev KD Abstract OBJECTIVE: The aim of the study was to find the most rational approach to postoperative pain relief in the complex of intensive care for the acute and early periods of traumatic diseasein elderly patients. PATIENTS AND METHODS:...
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Related Articles[Practices evalutation of Missed miscarriage diagnosis in gynecologic emergency service in Tours CHU]. Gynecol Obstet Fertil Senol. 2020 Apr 02;: Authors: Cohen-Steiner C, Ouldamer L Abstract INTRODUCTION: In the gynecology emergency departments, a pregnancy of uncertain viability is diagnosed in 29% of all first-trimester pregnancy medical consultations that require an ultrasound. The question of pregnancy viability is therefore common...
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Related ArticlesRisk of Complication at the Time of Laparoscopic Hysterectomy; A Prediction Model Built from The National Surgical Quality Improvement Program Database. Am J Obstet Gynecol. 2020 Apr 02;: Authors: Pepin KJ, Cook EF, Cohen SL Abstract BACKGROUND: While laparoscopic hysterectomy is well-established as a favorable mode of hysterectomy due to decreased perioperative complications, there is still room for improvement in quality of care. Though...
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Related ArticlesThe Society of Thoracic Surgeons Adult Cardiac Surgery Database: 2020 Update on Outcomes and Research. Ann Thorac Surg. 2020 Apr 02;: Authors: Bowdish ME, D'Agostino RS, Thourani VH, Desai N, Shahian DM, Fernandez FG, Badhwar V Abstract The Society of Thoracic Surgeons Adult Cardiac Surgery Database is the most mature and comprehensive database in cardiac surgery and one of the most respected clinical data registries in health care. It...
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Related ArticlesThe validity of surface EMG of extra-diaphragmatic muscles in assessing respiratory responses during mechanical ventilation: A systematic review. Pulmonology. 2020 Apr 01;: Authors: AbuNurah HY, Russell DW, Lowman JD Abstract PURPOSE: Evidence supporting the utilization of surface EMG (sEMG) of extra-diaphragmatic muscles for monitoring of mechanical ventilation (MV) assistance is unclear. The purpose of this review was to assess the...
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Related ArticlesFailure on a Vascular Surgery Board-American Board of Surgery Examination does not predict cardiovascular outcomes in the Society for Vascular Surgery Vascular Quality Initiative. J Vasc Surg. 2020 Apr 01;: Authors: Kraiss LW, Al-Dulaimi R, Cronenwett JL, Goodney PP, Clair DG, Hallett JJ, Rhodes R, Mills JL, Presson AP, Brooke BS Abstract OBJECTIVE: The Vascular Surgery Board of the American Board of Surgery (VSB-ABS) Qualifying and Certifying...
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Related ArticlesLess guessing, more evidence in identifying patients least fit for cytoreductive surgery in advanced ovarian cancer: A triage algorithm to individualize surgical management. Gynecol Oncol. 2020 Apr 01;: Authors: Narasimhulu DM, Kumar A, Weaver AL, Langstraat CL, Cliby WA Abstract OBJECTIVE: We previously reported an algorithm that identifies women at high risk of postoperative morbidity & mortality (M/M) as a tool to triage between...
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Related ArticlesEmanating the specialty clinical practices in Ayurveda: Preliminary observations from the Arthritis clinic and its implications. J Ayurveda Integr Med. 2020 Apr 01;: Authors: Rastogi S Abstract Despite their historical praise, specialty studies and practices are not generally seen in current Ayurvedic education and practice. Current Ayurvedic education by and large is devoid of training programs focusing upon specialty based health care...
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Related ArticlesThe views of physicians and nurses on the potentials of an electronic assessment system for recognizing the needs of patients in palliative care. BMC Palliat Care. 2020 Apr 04;19(1):45 Authors: Radionova N, Becker G, Mayer-Steinacker R, Gencer D, Rieger MA, Preiser C Abstract OBJECTIVES: Patients in oncological and palliative care (PC) often have complex needs, which require a comprehensive treatment approach. The assessment of patient-reported...
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