Microorganisms, Vol. 8, Pages 523: Autophagic Proteome in Two Saccharomyces cerevisiae Strains During Second Fermentation for Sparkling Wine Elaboration Microorganisms doi: 10.3390/microorganisms8040523 Authors: Porras-Agüera Moreno-García González-Jiménez Mauricio Moreno García-Martínez A correlation between autophagy and autolysis has been proposed in order to acceleratethe acquisition of wine organoleptic properties during sparkling wine elaboration. In this context,...
Mon Apr 06, 2020 03:00
Microorganisms, Vol. 8, Pages 524: Phylogenetic Analysis of Bacillus cereus sensu lato Isolates from Commercial Bee Pollen Using tRNACys-PCR Microorganisms doi: 10.3390/microorganisms8040524 Authors: José Luis Hernández Flores Diana Salinas Landaverde Yonuen Pacheco Huerta Vania Lizeth Guerra Castillo María de los Ángeles Barrios Sánchez Iván Arvizu Hernández Miguel Ángel Ramos López Erika Álvarez Hidalgo George H. Jones Juan Campos Guillén Endospore-forming...
Mon Apr 06, 2020 03:00
Microorganisms, Vol. 8, Pages 525: Human Cytomegalovirus Infection Suppresses CD34+ Progenitor Cell Engraftment in Humanized Mice Microorganisms doi: 10.3390/microorganisms8040525 Authors: Lindsey B. Crawford Rebecca Tempel Daniel N. Streblow Andrew D. Yurochko Felicia D. Goodrum Jay A. Nelson Patrizia Caposio Human cytomegalovirus (HCMV) infection is a serious complication in hematopoietic stem cell transplant (HSCT) recipients due to virus-induced myelosuppression...
Mon Apr 06, 2020 03:00
Molbank, Vol. 2020, Article M1124: Dimethyl 2-(1-methyl-3-oxo-1,3-dihydroisobenzofuran-1-yl)malonate
Molbank, Vol. 2020, Article M1124: Dimethyl 2-(1-methyl-3-oxo-1,3-dihydroisobenzofuran-1-yl)malonate Molbank doi: 10.3390/M1124 Authors: Mola Filosa Massa In this work we report a facile access to a 3,3-disubstituted isobenzofuranone by tandem addition/cyclization reaction to methyl 2-acetylbenzoate in the presence of dimethyl malonate, under basic conditions.
Mon Apr 06, 2020 03:00
Molecules, Vol. 25, Pages 1679: Photoprotective Effect of Dietary Galacto-Oligosaccharide (GOS) in Hairless Mice via Regulation of the MAPK Signaling Pathway Molecules doi: 10.3390/molecules25071679 Authors: Min Geun Suh Gi Yeon Bae Kyungae Jo Jin Man Kim Ki-Bae Hong Hyung Joo Suh This study investigated the suppression of photoaging by galacto-oligosaccharide (GOS) ingestion following exposure to ultraviolet (UV) radiation. To investigate its photoprotective effects,...
Mon Apr 06, 2020 03:00
Molecules, Vol. 25, Pages 1680: Discovery of Novel Inhibitor for WNT/β-Catenin Pathway by Tankyrase 1/2 Structure-Based Virtual Screening Molecules doi: 10.3390/molecules25071680 Authors: Li Liang Lu Zeng Zhang Ma Liu Wang Zhou Chen Aberrant activation of the WNT/β-catenin signaling pathway is implicated in various types of cancers. Inhibitors targeting the Wnt signaling pathway are intensively studied in the current cancer research field,...
Mon Apr 06, 2020 03:00
Molecules, Vol. 25, Pages 1678: Polymeric Coatings Based on Water-Soluble Trimethylammonium Copolymers for Antifouling Applications Molecules doi: 10.3390/molecules25071678 Authors: Artemis Tsagdi Denisa Druvari Dionisios Panagiotaras Pavlos Avramidis Vlasoula Bekiari Joannis K. Kallitsis Crosslinked polymeric materials based on a quaternary trimethylammonium compound were developed and evaluated as potential antifouling coatings. For this purpose, two water-soluble random...
Mon Apr 06, 2020 03:00
Nanomaterials, Vol. 10, Pages 693: A Novel Hybrid Nanosystem Integrating Cytotoxic and Magnetic Properties as a Tool to Potentiate Melanoma Therapy Nanomaterials doi: 10.3390/nano10040693 Authors: Cruz Pinho Soveral Ascensão Matela Reis Gaspar Cancer is a major health concern and the prognosis is often poor. Significant advances in nanotechnology are now driving a revolution in cancer detection and treatment. The goal of this study was to develop a novel hybrid...
Mon Apr 06, 2020 03:00
Nanomaterials, Vol. 10, Pages 694: Tb3+/Eu3+ Complex-Doped Rigid Nanoparticles in Transparent Nanofibrous Membranes Exhibit High Quantum Yield Fluorescence Nanomaterials doi: 10.3390/nano10040694 Authors: Peng Lu Yanxin Wang Linjun Huang Sixian Lian Yao Wang Jianguo Tang Laurence A. Belfiore Matt J. Kipper In this study, transparent membranes containing luminescent Tb3+ and Eu3+ complex-doped silica nanoparticles were prepared via electrospinning. We prepared the...
Mon Apr 06, 2020 03:00
Nanomaterials, Vol. 10, Pages 691: The Effect of Vacancies on Grain Boundary Segregation in Ferromagnetic fcc Ni Nanomaterials doi: 10.3390/nano10040691 Authors: Mazalová Všianská Pavlů Šob This work presents a comprehensive and detailed ab initio study of interactions between the tilt 5(210) grain boundary (GB), impurities X (X = Al, Si) and vacancies (Va) in ferromagnetic fcc nickel. To obtain reliable results, two methods of structure relaxation were employed: the automatic...
Mon Apr 06, 2020 03:00
Nanomaterials, Vol. 10, Pages 692: Effect of TiO2 and ZnO Nanoparticles on the Performance of Dielectric Nanofluids Based on Vegetable Esters During Their Aging Nanomaterials doi: 10.3390/nano10040692 Authors: Fernández Valiente Ortiz Renedo Ortiz Over the last few decades the insulating performance of transformer oils has been broadly studied under the point of view of nanotechnology, which tries to improve the insulating and heat dissipation performance of transformer...
Mon Apr 06, 2020 03:00
Nanomaterials, Vol. 10, Pages 690: Gold Nanoparticles Mediate Improved Detection of β-amyloid Aggregates by Fluorescence Nanomaterials doi: 10.3390/nano10040690 Authors: Pedro Jara-Guajardo Pablo Cabrera Freddy Celis Mónica Soler Isadora Berlanga Nicole Parra-Muñoz Gerardo Acosta Fernando Albericio Fanny Guzman Marcelo Campos Alejandra Alvarez Francisco Morales-Zavala Marcelo J Kogan The early detection of the amyloid beta peptide aggregates involved...
Mon Apr 06, 2020 03:00
Nanomaterials, Vol. 10, Pages 689: Investigation of Electrical Properties and Reliability of GaN-Based Micro-LEDs Nanomaterials doi: 10.3390/nano10040689 Authors: Ke Zhang Yibo Liu Hoi-sing Kwok Zhaojun Liu In this paper, we report high-performance Micro-LEDs on sapphire substrates, with pixel size scaling to 20 µm and an ultra-high current density of 9902 A/cm2. The forward voltages (VF) of the devices ranged from 2.32 V to 2.39 V under an injection current density...
Mon Apr 06, 2020 03:00
Nutrients, Vol. 12, Pages 1010: Flavonoids as Epigenetic Modulators for Prostate Cancer Prevention Nutrients doi: 10.3390/nu12041010 Authors: Izzo Naponelli Bettuzzi Prostate cancer (PCa) is a multifactorial disease with an unclear etiology. Due to its high prevalence, long latency, and slow progression, PCa is an ideal target for chemoprevention strategies. Many research studies have highlighted the positive effects of natural flavonoids on chronic diseases, including PCa....
Mon Apr 06, 2020 03:00
Nutrients, Vol. 12, Pages 1009: Food Sources and Nutrient Intakes of Filipino Working Adults Nutrients doi: 10.3390/nu12041009 Authors: Angeles-Agdeppa Custodio Nutrition is an integral part of economic development, since it influences workers’ healthand productivity. This study evaluated the usual nutrient intakes and food sources of workingadults. We conducted a cross-sectional survey that involved 1264 selected working adults aged 19to 59 years old from randomly selected...
Mon Apr 06, 2020 03:00
Nutrients, Vol. 12, Pages 1008: Effects of Age on Acute Appetite-Related Responses to Whey-Protein Drinks, Including Energy Intake, Gastric Emptying, Blood Glucose, and Plasma Gut Hormone Concentrations—A Randomized Controlled Trial Nutrients doi: 10.3390/nu12041008 Authors: Caroline Giezenaar Kylie Lange Trygve Hausken Karen L. Jones Michael Horowitz Ian Chapman Stijn Soenen Protein-rich supplements are used commonly to increase energy intake in undernourished older...
Mon Apr 06, 2020 03:00
Nutrients, Vol. 12, Pages 1006: Levels of the Novel Endogenous Antagonist of Ghrelin Receptor, Liver-Enriched Antimicrobial Peptide-2, in Patients with Rheumatoid Arthritis Nutrients doi: 10.3390/nu12041006 Authors: Vera Francisco Sulay Tovar Javier Conde Jesús Pino Antonio Mera Francisca Lago Miguel Angel González-Gay Carlos Dieguez Oreste Gualillo Rheumatoid arthritis (RA) is a debilitating, chronic, inflammatory, autoimmune disease associated with cachexia....
Mon Apr 06, 2020 03:00
Nutrients, Vol. 12, Pages 1007: Ameliorating Chronic Kidney Disease Using a Whole Food Plant-Based Diet Nutrients doi: 10.3390/nu12041007 Authors: Kathleen E. Adair Rodney G. Bowden Novel approaches to ameliorating chronic kidney disease (CKD) are warranted as most patients are undiagnosed until they begin displaying symptoms of kidney failure. There is increasing evidence that a whole food plant-based (WFPB) diet may offer benefits that slow the progression of CKD, decrease the incidence...
Mon Apr 06, 2020 03:00
Nutrients, Vol. 12, Pages 1005: Treatment with Modified Extracts of the Microalga Planktochlorella nurekis Attenuates the Development of Stress-Induced Senescence in Human Skin Cells Nutrients doi: 10.3390/nu12041005 Authors: Jagoda Adamczyk-Grochala Maciej Wnuk Magdalena Duda Janusz Zuczek Anna Lewinska More recently, we have proposed a safe non-vector approach to modifying the biochemical profiles of the microalga Planktochlorella nurekis and obtained twelve clones with...
Mon Apr 06, 2020 03:00
Pharmaceutics, Vol. 12, Pages 327: Preparation, Physicochemical Properties, and In Vitro Toxicity towards Cancer Cells of Novel Types of Arsonoliposomes Pharmaceutics doi: 10.3390/pharmaceutics12040327 Authors: Zagana Mourtas Basta Antimisiaris Arsonoliposomes (ARSL) are liposomes that incorporate arsonolipids (ARS) in their membranes. They have demonstrated significant toxicity towards cancer cells, while being less toxic towards normal cells. In this study, we sought to...
Mon Apr 06, 2020 03:00
Plants, Vol. 9, Pages 461: Loop Mediated Isothermal Amplification: Principles and Applications in Plant Virology Plants doi: 10.3390/plants9040461 Authors: Panno Matić Tiberini Caruso Bella Torta Stassi Davino In the last decades, the evolution of molecular diagnosis methods has generated different advanced tools, like loop-mediated isothermal amplification (LAMP). Currently, it is a well-established technique, applied in different fields, such as the medicine,...
Mon Apr 06, 2020 03:00
Plants, Vol. 9, Pages 460: Silicon in Horticultural Crops: Cross-talk, Signaling, and Tolerance Mechanism under Salinity Stress Plants doi: 10.3390/plants9040460 Authors: Musa Al Murad Abdul Latif Khan Sowbiya Muneer Agricultural land is extensively affected by salinity stress either due to natural phenomena or by agricultural practices. Saline stress possesses two major threats to crop growth: osmotic stress and oxidative stress. The response of these changes is often accompanied...
Mon Apr 06, 2020 03:00
Religions, Vol. 11, Pages 172: The Saving Grace of America’s Green Jeremiad Religions doi: 10.3390/rel11040172 Authors: Gatta By the late seventeenth century, Puritan leaders in colonial America were bemoaning what they perceived to be the betrayal of New England’s godly “errand into the wilderness.” In election sermons they mourned the community’s backsliding from its global mission as a “city upon a hill.” Such doomsday rhetoric...
Mon Apr 06, 2020 03:00
Sci, Vol. 2, Pages 24: SOX2OT Long Noncoding RNA Is Regulated by the UPR in Oestrogen Receptor-Positive Breast Cancer Sci doi: 10.3390/sci2020024 Authors: Ferraro-Peyret Askarian-Amiri Sarkar Joseph Hansji Baguley Leung Endoplasmic reticulum (ER) stress perturbs cell homeostasis and induces the unfolded protein response (UPR). In breast cancer, this process is activated by oestrogen deprivation and is associated with tamoxifen resistance. We present evidence...
Mon Apr 06, 2020 03:00
Vaccines, Vol. 8, Pages 167: Infection with Toxocara canis Inhibits the Production of IgE Antibodies to α-Gal in Humans: Towards a Conceptual Framework of the Hygiene Hypothesis? Vaccines doi: 10.3390/vaccines8020167 Authors: Adnan Hodžić Lourdes Mateos-Hernández Emilie Fréalle Patricia Román-Carrasco Pilar Alberdi Muriel Pichavant Veronica Risco-Castillo Delphine Le Roux Jérôme Vicogne Wolfgang Hemmer Herbert Auer Ines Swoboda Georg Gerhard Duscher José...
Mon Apr 06, 2020 03:00
Vaccines, Vol. 8, Pages 169: A Pentavalent Epstein-Barr Virus-Like Particle Vaccine Elicits High Titers of Neutralizing Antibodies against Epstein-Barr Virus Infection in Immunized Rabbits Vaccines doi: 10.3390/vaccines8020169 Authors: Gabriela M. Escalante Joslyn Foley Lorraine Z. Mutsvunguma Esther Rodriguez David H. Mulama Murali Muniraju Peng Ye Anne K. Barasa Javier Gordon Ogembo Primary infection with Epstein-Barr virus (EBV) is associated with acute infectious...
Mon Apr 06, 2020 03:00
Vaccines, Vol. 8, Pages 168: Comparison of Immunogenicity and Protective Efficacy of PPR Live Attenuated Vaccines (Nigeria 75/1 and Sungri 96) Administered by Intranasal and Subcutaneous Routes Vaccines doi: 10.3390/vaccines8020168 Authors: Mana Mahapatra M. Selvaraj Satya Parida Following the successful eradication of rinderpest, the World Organization of Animal Health (OIE) and the Food and Agriculture Organization (FAO) have set a goal to eradicate peste des petits ruminants...
Mon Apr 06, 2020 03:00
Vaccines, Vol. 8, Pages 166: Immunization against ROS1 by DNA Electroporation Impairs K-Ras-Driven Lung Adenocarcinomas Vaccines doi: 10.3390/vaccines8020166 Authors: Federica Riccardo Giuseppina Barutello Angela Petito Lidia Tarone Laura Conti Maddalena Arigoni Chiara Musiu Stefania Izzo Marco Volante Dario Livio Longo Irene Fiore Merighi Mauro Papotti Federica Cavallo Elena Quaglino Non-small cell lung cancer (NSCLC) is still the leading cause...
Mon Apr 06, 2020 03:00
Veterinary Sciences, Vol. 7, Pages 39: Assessment of Intra- and Inter-observer Measurement Variability in a Radiographic Metacarpophalangeal Joint Osteophytosis Scoring System for the Horse Veterinary Sciences doi: 10.3390/vetsci7020039 Authors: Luca Lacitignola Annarita Imperante Francesco Staffieri Rocco De De Siena Pasquale De Luca Arianna Muci Antonio Crovace The study evaluated the intra- and inter-observer measurement variability of an osteophytosis metacarpophalangeal...
Mon Apr 06, 2020 03:00
Viruses, Vol. 12, Pages 406: Antiviral Agents: Discovery to Resistance Viruses doi: 10.3390/v12040406 Authors: Catherine S. Adamson In the midst of the SARS-CoV-2/Covid-19 outbreak the need for research into, and development of, antiviral agents is brought into sharp focus worldwide for scientists, governments and the public alike [...]
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Viruses, Vol. 12, Pages 405: Interferon-λ Attenuates Rabies Virus Infection by Inducing Interferon-Stimulated Genes and Alleviating Neurological Inflammation Viruses doi: 10.3390/v12040405 Authors: Yingying Li Ling Zhao Zhaochen Luo Yachun Zhang Lei Lv Jianqing Zhao Baokun Sui Fei Huang Min Cui Zhen F. Fu Ming Zhou Rabies, caused by rabies virus (RABV), is a fatal neurological disease that still causes more than 59,000 human deaths each year. Type III interferon...
Mon Apr 06, 2020 03:00
Viruses, Vol. 12, Pages 403: Genome Analysis and Replication Studies of the African Green Monkey Simian Foamy Virus Serotype 3 Strain FV2014 Viruses doi: 10.3390/v12040403 Authors: Sandra M. Fuentes Eunhae H. Bae Subhiksha Nandakumar Dhanya K. Williams Arifa S. Khan African green monkey (AGM) spumaretroviruses have been less well-studied than other simian foamy viruses (SFVs). We report the biological and genomic characterization of SFVcae_FV2014, which was the first foamy...
Mon Apr 06, 2020 03:00
Viruses, Vol. 12, Pages 404: In Silico Discovery of Candidate Drugs against Covid-19 Viruses doi: 10.3390/v12040404 Authors: Claudia Cava Gloria Bertoli Isabella Castiglioni Previous studies reported that Angiotensin converting enzyme 2 (ACE2) is the main cell receptor of SARS-CoV and SARS-CoV-2. It plays a key role in the access of the virus into the cell to produce the final infection. In the present study we investigated in silico the basic mechanism of ACE2 in the lung and...
Mon Apr 06, 2020 03:00
Water, Vol. 12, Pages 1037: A Direct Approach for the Near-Optimal Design of Water Distribution Networks Based on Power Use Water doi: 10.3390/w12041037 Authors: Juan Saldarriaga Diego Páez Camilo Salcedo Paula Cuero Laura Lunita López Natalia León David Celeita In recent years, iterative computational techniques have been considered as the most effective methods to tackle the problem of Water Distribution System (WDS) minimum-cost design. Given their stochastic nature,...
Mon Apr 06, 2020 03:00
Water, Vol. 12, Pages 1038: Hydrological Characterization of Watering Ponds in Rangeland Farms in the Southwest Iberian Peninsula Water doi: 10.3390/w12041038 Authors: Ubaldo Marín-Comitre Susanne Schnabel Manuel Pulido-Fernández Watering ponds are an important source of drinking water supply for livestock in semi-arid rangelands. Understanding the hydrological functioning of this kind of infrastructures is crucial for efficient water management in areas where water resources are...
Mon Apr 06, 2020 03:00
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