Dramatic recovery of vision in patient with acute central retinal artery occlusion treated with local intra-arterial tissue plasminogen activator 1hby Margolin, E. A., Rai, A., Goldfarb, J., Zaslavsky, K., Kohly, R., Nicholson, P. via BMJ Case Reports Last 6 Issues Central retinal artery occlusion (CRAO) is a devastating disease resulting in severe visual loss in most cases. It has no proven treatment, and a variety of management options used clinically all have dismal rate of success. We report outcome of treatment with local intra-arterial thrombolysis administered 2.75 hours after devastating visual loss from incomplete CRAO.