Microorganisms, Vol. 8, Pages 270: In Vitro Zika Virus Infection of Human Neural Progenitor Cells: Meta-Analysis of RNA-Seq Assays Microorganisms doi: 10.3390/microorganisms8020270 Authors: Rossella Gratton Paola Maura Tricarico Almerinda Agrelli Heverton Valentim Colaço da Silva Lucas Coêlho Bernardo Sergio Crovella Antonio Victor Campos Coelho Ronald Rodrigues de Moura Lucas André Cavalcanti Brandão The Zika virus (ZIKV) is an emergent arthropod-borne virus...
Mon Feb 17, 2020 02:00
Microorganisms, Vol. 8, Pages 269: Gut Microbiota, Antibiotic Therapy and Antimicrobial Resistance: A Narrative Review Microorganisms doi: 10.3390/microorganisms8020269 Authors: Pilmis Le Monnier Zahar Antimicrobial resistance is a major concern. Epidemiological studies have demonstrated direct relationships between antibiotic consumption and emergence/dissemination of resistant strains. Within the last decade, authors confounded spectrum activity and ecological effects and...
Mon Feb 17, 2020 02:00
Microorganisms, Vol. 8, Pages 268: Effects of Composting Different Types of Organic Fertilizer on the Microbial Community Structure and Antibiotic Resistance Genes Microorganisms doi: 10.3390/microorganisms8020268 Authors: Zhou Yao Organic fertilizer is a major carrier that stores and transmits antibiotic resistance genes (ARGs). In the environment, due to the application of organic fertilizers in agriculture, the increasing diversity and abundance of ARGs poses a potential threat...
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 893: Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues Molecules doi: 10.3390/molecules25040893 Authors: Danielly C. Ferraz da Costa Luciana Pereira Rangel Mafalda Maria Duarte da Cunha Martins-Dinis Giulia Diniz da Silva Ferretti Vitor F. Ferreira Jerson L. Silva This review aims to explore the potential of resveratrol, a polyphenol stilbene, and beta-lapachone, a naphthoquinone, as well as their derivatives, in the development...
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Molecules, Vol. 25, Pages 892: Inhibitory Effects of Raw-Extract Centella asiatica (RECA) on Acetylcholinesterase, Inflammations, and Oxidative Stress Activities via In Vitro and In Vivo Molecules doi: 10.3390/molecules25040892 Authors: Hafiz Mohd Amin Johari James Teh Salleh Adenan Centella asiatica (C. asiatica) is one of the medicinal plants that has been reported to exert comprehensive neuroprotection in vitro and in vivo. In view of this, the present study was...
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 890: Silk Particle Production Based on silk/PVA Phase Separation Using a Microfabricated Co-flow Device Molecules doi: 10.3390/molecules25040890 Authors: Montoya Peterson Ornell Albrecht Coburn Polymeric particles are ideal drug delivery systems due to their cellular uptake-relevant size. Microparticles could be developed for direct injection of drug formulations into a diseased site, such as a tumor, allowing for drug retention and slow drug...
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 889: Selenium and Zinc Biofortification of Pleurotus eryngii Mycelium and Fruiting Bodies as a Tool for Controlling Their Biological Activity Molecules doi: 10.3390/molecules25040889 Authors: Piotr Zięba Katarzyna Kała Anna Włodarczyk Agnieszka Szewczyk Edward Kunicki Agnieszka Sękara Bożena Muszyńska Pleurotus eryngii (DC:Fr.) Quel. is a cultivated mushroom of high culinary value and medicinal properties. Mycelium of P. eryngii is characterized...
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 891: Nanostructured Silicon as Potential Anode Material for Li-Ion Batteries Molecules doi: 10.3390/molecules25040891 Authors: Raić Mikac Marić Štefanić Škrabić Gotić Ivanda : Commercial micrometer silicon (Si) powder was investigated as a potential anode material for lithium ion (Li-ion) batteries. The characterization of this powder showed the mean particle size of approx.75.2 nm, BET surface area of 10.6 m2/g and average pore size...
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 887: Untargeted HILIC-MS-Based Metabolomics Approach to Evaluate Coffee Roasting Process: Contributing to an Integrated Metabolomics Multiplatform Molecules doi: 10.3390/molecules25040887 Authors: Pérez-Míguez Castro-Puyana Sánchez-López Plaza Marina An untargeted metabolomics strategy using hydrophilic interaction chromatography-mass spectrometry (HILIC-MS) was developed in this work enabling the study of the coffee roasting process. Green...
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 888: Synthesis and In Vitro Anticancer Evaluation of Novel Chrysin and 7-Aminochrysin Derivatives Molecules doi: 10.3390/molecules25040888 Authors: Mayer Keglevich Ábrányi-Balogh Szigetvári Dékány Szántay Hazai Chrysin is a naturally occurring flavonoid with mild anticancer activity. In this paper we report the synthesis of new chrysin derivatives alkylated with N-phenylchloroacetamides in position 7. A novel method was developed for...
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 885: Endothelium-Independent Vasodilatory Effects of Isodillapiolglycol Isolated from Ostericum citriodorum Molecules doi: 10.3390/molecules25040885 Authors: Luo Chen Wang Yin Liu Zhang Yang : Ostericum citriodorum is a plant with a native range in China used in herbal medicine for treating angina pectoris. In this study, we investigated the vasodilatory effects of isodillapiolglycol (IDG), which is one of the main ingredients isolated...
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 884: Newly Developed Prodrugs and Prodrugs in Development; an Insight of the Recent Years Molecules doi: 10.3390/molecules25040884 Authors: Anas Najjar Abderrahman Najjar Rafik Karaman Background: The design and development of prodrugs is the most common and effective strategy to overcome pharmacokinetic and pharmacodynamic drawbacks of active drugs. A respected number of prodrugs have been reached the drugs market throughout history and the recent years...
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 883: Isolation, Structure Determination, and Synthesis of Cyclic Tetraglutamic Acids from Box Jellyfish Species Alatina alata and Chironex yamaguchii Molecules doi: 10.3390/molecules25040883 Authors: Reinicke Kitatani Masoud Galbraith Yoshida Igarashi Nagasawa Berger Yanagihara Nagai Horgen Cubozoan nematocyst venoms contain known cytolytic and hemolytic proteins, but small molecule components have not been previously...
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 882: Reduced-Dimensionality Quantum Dynamics Study of the 3Fe(CO)4 + H2 1FeH2(CO)4 Spin-inversion Reaction Molecules doi: 10.3390/molecules25040882 Authors: Takayanagi Watabe Miyazaki Many chemical reactions of transition metal compounds involve a change in spin state via spin inversion, which is induced by relativistic spin-orbit coupling. In this work, we theoretically study the efficiency of a typical spin-inversion reaction, 3Fe(CO)4 + H2 1FeH2(CO)4....
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 881: Oligosaccharides and Complex Carbohydrates: A New Paradigm for Cranberry Bioactivity Molecules doi: 10.3390/molecules25040881 Authors: Coleman Ferreira Cranberry is a well-known functional food, but the compounds directly responsible for many of its reported health benefits remain unidentified. Complex carbohydrates, specifically xyloglucan and pectic oligosaccharides, are the newest recognized class of biologically active compounds identified in cranberry...
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 886: Facile Synthesis of Graphene from Waste Tire/Silica Hybrid Additives and Optimization Study for the Fabrication of Thermally Enhanced Cement Grouts Molecules doi: 10.3390/molecules25040886 Authors: Berktas Ghafar Fontana Caputcu Menceloglu Okan This work evaluates the effects of newly designed graphene/silica hybrid additives on the properties of cementitious grout. In the hybrid structure, graphene nanoplatelet (GNP) obtained from...
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 879: Candida antarctica Lipase A-Based Enantiorecognition of a Highly Strained 4-Dibenzocyclooctynol (DIBO) Used for PET Imaging Molecules doi: 10.3390/molecules25040879 Authors: Sirén Dahlström Puttreddy Rissanen Salminen Scheinin Li Liljeblad The enantiomers of aromatic 4-dibenzocyclooctynol (DIBO), used for radiolabeling and subsequent conjugation of biomolecules to form radioligands for positron emission tomography (PET), were...
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 880: C-H Functionalization via Iron-Catalyzed Carbene-Transfer Reactions Molecules doi: 10.3390/molecules25040880 Authors: Empel Jana Koenigs The direct C-H functionalization reaction is one of the most efficient strategies by which to introduce new functional groups into small organic molecules. Over time, iron complexes have emerged as versatile catalysts for carbine-transfer reactions with diazoalkanes under mild and sustainable reaction conditions....
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 877: Unexpected Reaction Pathway of the Alpha-Aminoalkyl Radical Derived from One-Electron Oxidation of S-Alkylglutathiones Molecules doi: 10.3390/molecules25040877 Authors: Pedzinski Bobrowski Marciniak Filipiak Laser flash photolysis and high-resolution mass spectrometry were used to investigate the mechanism of one-electron oxidation of two S-alkylglutathiones using 3-carboxybenzophenone (3CB) as a photosensitizer. This report indicates an unexpected...
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 876: The Content of Selected Minerals, Bioactive Compounds, and the Antioxidant Properties of the Flowers and Fruit of Selected Cultivars and Wildly Growing Plants of Sambucus nigra L. Molecules doi: 10.3390/molecules25040876 Authors: Młynarczyk Walkowiak-Tomczak Staniek Kidoń Łysiak This study compared the mineral content and bioactive properties of flowers and fruit coming from wild elderberry plants with those of flowers and fruit harvested...
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 878: Antibacterial Activity and Pharmacokinetic Profile of a Promising Antibacterial Agent: 22-(2-Amino-phenylsulfanyl)-22-Deoxypleuromutilin Molecules doi: 10.3390/molecules25040878 Authors: Xiangyi Zuo Xi Fang Zhaosheng Zhang Zhen Jin Gaolei Xi Yahong Liu Youzhi Tang A new pleuromutilin derivative, 22-(2-amino-phenylsulfanyl)-22-deoxypleuromutilin (amphenmulin), has been synthesized and proved excellent in vitro and in vivo efficacy than...
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 875: Ultrasound-Assisted Mild Heating Treatment Improves the Emulsifying Properties of 11S Globulins Molecules doi: 10.3390/molecules25040875 Authors: Linlin Liu Jianhua Zeng Bingyu Sun Na Zhang Yinyuan He Yanguo Shi Xiuqing Zhu Ultrasonic technology is often used to modify proteins. Here, we investigated the effects of ultrasound alone or in combination with other heating methods on emulsifying properties and structure of glycinin (11S globulin)....
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 874: Novel Blood–Brain Barrier Shuttle Peptides Discovered through the Phage Display Method Molecules doi: 10.3390/molecules25040874 Authors: Majerova Hanes Olesova Sinsky Pilipcinec Kovac Delivery of therapeutic agents into the brain is a major challenge in central nervous system drug development. The blood–brain barrier (BBB) prevents access of biotherapeutics to their targets in the central nervous system and, therefore, prohibits...
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 873: Modeling to Understand Plant Protein Structure-Function Relationships—Implications for Seed Storage Proteins Molecules doi: 10.3390/molecules25040873 Authors: Rasheed Markgren Hedenqvist Johansson Proteins are among the most important molecules on Earth. Their structure and aggregation behavior are key to their functionality in living organisms and in protein-rich products. Innovations, such as increased computer size and power, together with...
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 872: Enhanced Degradation of Naproxen by Immobilization of Bacillus thuringiensis B1(2015b) on Loofah Sponge Molecules doi: 10.3390/molecules25040872 Authors: Dzionek Wojcieszyńska Adamczyk-Habrajska Guzik The naproxen-degrading bacterium Bacillus thuringiensis B1(2015b) was immobilised onto loofah sponge and introduced into lab-scale trickling filters. The trickling filters constructed for this study additionally contained stabilised microflora...
Mon Feb 17, 2020 02:00
Molecules, Vol. 25, Pages 871: Preservative Effects of Gelatin Active Coating Containing Eugenol and Higher CO2 Concentration Modified Atmosphere Packaging on Chinese Sea bass (Lateolabrax maculatus) during Superchilling (−0.9 °C) Storage Molecules doi: 10.3390/molecules25040871 Authors: Zhou Li Fang Mei Xie The purpose of this research was to explore the fresh keeping effect of modified atmosphere packaging (MAP) with different gas ratios combined with gelatin active...
Mon Feb 17, 2020 02:00
Nanomaterials, Vol. 10, Pages 344: Adsorption and Diffusion of Hydrogen in Carbon Honeycomb Nanomaterials doi: 10.3390/nano10020344 Authors: Qin Qin Tingwei Sun Hanxiao Wang Pascal Brault Haojie An Lu Xie Qing Peng Carbon honeycomb has a nanoporous structure with good mechanical properties including strength. Here we investigate the adsorption and diffusion of hydrogen in carbon honeycomb via grand canonical Monte Carlo simulations and molecular dynamics simulations...
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Nanomaterials, Vol. 10, Pages 343: The Effect of Fatty Acids and BSA Purity on Synthesis and Properties of Fluorescent Gold Nanoclusters Nanomaterials doi: 10.3390/nano10020343 Authors: Andrýsková Šišková Michetschlägerová Jiráková Kubala Jirák Fluorescent gold nanoclusters (AuNCs) are envisaged as a novel type of fluorophores. This work reports on the first comparative study investigating the effect of presence/absence/abundance of fatty acids (namely palmitic acid,...
Mon Feb 17, 2020 02:00
Nanomaterials, Vol. 10, Pages 340: Structural Features and Photoelectric Properties of Si-Doped GaAs under Gamma Irradiation Nanomaterials doi: 10.3390/nano10020340 Authors: Shen Fang Ding Xiao Xiang Yang Jiang Zu Qiao GaAs has been demonstrated to be a promising material for manufacturing semiconductor light-emitting devices and integrated circuits. It has been widely used in the field of aerospace, due to its high electron mobility and wide band gap....
Mon Feb 17, 2020 02:00
Nanomaterials, Vol. 10, Pages 338: MOS Capacitance Measurements for PEALD TiO2 Dielectric Films Grown under Different Conditions and the Impact of Al2O3 Partial-Monolayer Insertion Nanomaterials doi: 10.3390/nano10020338 Authors: William Chiappim Marcos Watanabe Vanessa Dias Giorgio Testoni Ricardo Rangel Mariana Fraga Homero Maciel Sebastião dos Santos Filho Rodrigo Pessoa In this paper, we report the plasma-enhanced atomic layer deposition (PEALD) of TiO2 and...
Mon Feb 17, 2020 02:00
Nanomaterials, Vol. 10, Pages 342: Liquid-Plasma Hydrogenated Synthesis of Gray Titania with Engineered Surface Defects and Superior Photocatalytic Activity Nanomaterials doi: 10.3390/nano10020342 Authors: Feng Zhang Guang Feng Mengyun Hu Yanwei Huang Heping Zeng Defect engineering in photocatalysts recently exhibits promising performances in solar-energy-driven reactions. However, defect engineering techniques developed so far rely on complicated synthesis processes and...
Mon Feb 17, 2020 02:00
Nanomaterials, Vol. 10, Pages 339: Synthesis of Diatomite-Based Mesoporous Wool-Ball-Like Microspheres and Their Application for Toluene Total Oxidation Reaction Nanomaterials doi: 10.3390/nano10020339 Authors: Le Nguyen Le Lefèvre Dinh Hong Kim Le Diatomite (DE) has attracted considerable attention owing to its abundance, low cost, and potential for a wide variety of applications. This work reports the development of mesoporous wool-ball-like (WBL) microspheres...
Mon Feb 17, 2020 02:00
Nanomaterials, Vol. 10, Pages 337: Recent Advances in TiO2-Based Photocatalysts for Reduction of CO2 to Fuels Nanomaterials doi: 10.3390/nano10020337 Authors: Thang Phan Nguyen Dang Le Tri Nguyen Van-Huy Nguyen Thu-Ha Le Dai-Viet N. Vo Quang Thang Trinh Sa-Rang Bae Sang Youn Chae Soo Young Kim Quyet Van Le Titanium dioxide (TiO2) has attracted increasing attention as a candidate for the photocatalytic reduction of carbon dioxide (CO2) to convert anthropogenic...
Mon Feb 17, 2020 02:00
Nanomaterials, Vol. 10, Pages 341: Invasome: A Novel Nanocarrier for Transdermal Drug Delivery Nanomaterials doi: 10.3390/nano10020341 Authors: Babaie Bakhshayesh Ha Hamishehkar Kim Invasomes are novel vesicular systems that exhibit improved transdermal penetration compared to conventional liposomes. These vesicles contain phospholipids, ethanol, and terpene in their structures; these components confer suitable transdermal penetration properties to the soft vesicles....
Mon Feb 17, 2020 02:00
Nutrients, Vol. 12, Pages 509: Dietary Saturated Fatty Acids Modulate Pain Behaviour in Trauma-Induced Osteoarthritis in Rats Nutrients doi: 10.3390/nu12020509 Authors: Sunderajhan Sekar Sunil K Panchal Naga KR Ghattamaneni Lindsay Brown Ross Crawford Yin Xiao Indira Prasadam Osteoarthritis (OA) is a degenerative condition of joints, causing pain and swelling, and can be caused or worsened by trauma and obesity. The objectives of this study were to determine whether...
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Nutrients, Vol. 12, Pages 508: Protein-Related Dietary Parameters and Frailty Status in Older Community-Dwellers across Different Frailty Instruments Nutrients doi: 10.3390/nu12020508 Authors: Hélio J. Coelho-Júnior Riccardo Calvani Anna Picca Ivan O. Gonçalves Francesco Landi Roberto Bernabei Matteo Cesari Marco C. Uchida Emanuele Marzetti The present study investigated the associations between frailty status and (a) daily protein intake, (b) daily body weight-adjusted...
Mon Feb 17, 2020 02:00
Nutrients, Vol. 12, Pages 505: A Delayed Morning and Earlier Evening Time-Restricted Feeding Protocol for Improving Glycemic Control and Dietary Adherence in Men with Overweight/Obesity: A Randomized Controlled Trial Nutrients doi: 10.3390/nu12020505 Authors: Parr Devlin Radford Hawley We determined the effects of time-restricted feeding (TRF; 8 h/d) versus extended feeding (EXF; 15 h/d) on 24-h and postprandial metabolism and subjective opinions of TRF in men with overweight/obesity....
Mon Feb 17, 2020 02:00
Nutrients, Vol. 12, Pages 507: Characterising a Weight Loss Intervention in Obese Asthmatic Children
Nutrients, Vol. 12, Pages 507: Characterising a Weight Loss Intervention in Obese Asthmatic Children Nutrients doi: 10.3390/nu12020507 Authors: Eslick Jensen Collins Gibson Hilton Wood The prevalence of obesity in asthmatic children is high and is associated with worse clinical outcomes. We have previously reported that weight loss leads to improvements in lung function and asthma control in obese asthmatic children. The objectives of this secondary analysis were...
Mon Feb 17, 2020 02:00
Nutrients, Vol. 12, Pages 506: Gestational Diabetes Mellitus Treatment Schemes Modify Maternal Plasma Cholesterol Levels Dependent to Women´s Weight: Possible Impact on Feto-Placental Vascular Function Nutrients doi: 10.3390/nu12020506 Authors: Contreras-Duarte Carvajal Garchitorena Subiabre Fuenzalida Cantin Farías Leiva : Gestational diabetes mellitus (GDM) associates with fetal endothelial dysfunction (ED), which occurs independently of adequate glycemic...
Mon Feb 17, 2020 02:00
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