Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

Novel coronavirus 2019-nCoV: prevalence, biological and clinical characteristics comparison with SARS-CoV and MERS-CoV

OBJECTIVE: Human infections with zoonotic coronavirus contain emerging and reemerging pathogenic characteristics which have raised great public health concern. This study aimed at investigating the global prevalence, biological and clinical characteristics of novel coronavirus, Wuhan China (2019-nCoV), Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection outbreaks. MATERIALS AND METHODS: The data on the global outbreak of...

COVID-19 (Novel Coronavirus 2019) – recent trends

Thu Feb 27, 2020 18:06

The World Health Organization (WHO) has issued a warning that, although the 2019 novel coronavirus (COVID-19) from Wuhan City (China), is not pandemic, it should be contained to prevent the global spread. The COVID-19 virus was known earlier as 2019-nCoV. As of 12 February 2020, WHO reported 45,171 cases and 1115 deaths related to COVID-19. COVID-19 is similar to Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) virus in its pathogenicity, clinical spectrum, and epidemiology. Comparison of...

Novel Coronavirus 2019 (Sars-CoV2): a global emergency that needs new approaches?

Thu Feb 27, 2020 18:06

L'articolo Novel Coronavirus 2019 (Sars-CoV2): a global emergency that needs new approaches? sembra essere il primo su European Review.

BioMed Research International

Thu Feb 27, 2020 18:06

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The Changing Epidemiology of Hepatocellular Carcinoma : Experience of a Single Center

Aims. To analyze the main etiological factors and some clinical features of patients with hepatocellular carcinoma (HCC) at diagnosis and to compare them with those we described ten years ago. Materials and Methods. We compared two groups of patients with HCC, Group 1 consisting of 132 patients (82 M, 50 F) diagnosed in the 2003–2008 period and Group 2 including 119 patients (82 M, 37 F) diagnosed in the 2013–2018 period. For all patients, age, sex, viral markers, alcohol consumption, serum alpha-fetoprotein...

BioMed Research International

Thu Feb 27, 2020 15:35

Accuracy on Scanned Images of Full Arch Models with Orthodontic Brackets by Various Intraoral Scanners in the Presence of Artificial Saliva

Aim. This study aims to evaluate the accuracy of scanned images of 4 clinically used intraoral scanners (CS3600, i500, Trios3, Omnicam) when scanning the surface of full arch models with various kinds of orthodontic brackets in the presence of artificial saliva. Materials and Methods. Four study models were prepared; bonded with ceramic, metal, and resin brackets, respectively, and without brackets. Reference images were taken by scanning the models with an industrial scanner. Study models were then...

BioMed Research International

Thu Feb 27, 2020 10:05

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Auris Nasus Larynx

Reflux finding score and reflux symptom index as potential predictors for proton pump inhibitor response in globus pharyngeus patients: A prospective study

Publication date: Available online 26 February 2020Source: Auris Nasus LarynxAuthor(s): Laurentine Boom, Mireille Edens, Bas Rinia

Auris Nasus Larynx

Thu Feb 27, 2020 18:08

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ScienceDirect Publication: Brain Research Bulletin

Modulation of NR1 receptor by CaMKIIα plays an important role in chronic itch development in mice

Publication date: Available online 26 February 2020Source: Brain Research BulletinAuthor(s): Nan-Qi Li, Yang Tang, Si-Ting Huang, Xue-Ting Liu, Li-Ping Zeng, Hui Li, Li Wan

ScienceDirect Publication: Brain Research Bulletin

Thu Feb 27, 2020 18:08

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European Review » Rheumatology

A review of network meta-analysis comparing biologics in the treatment of rheumatoid arthritis

OBJECTIVE: Even though in recent years significant improvements have been made in the management of patients with rheumatoid arthritis due to the introduction of biologic agents, it is still difficult to identify the most effective and safest available treatment. The choice and comparison between biological agents are a challenge, for only limited head-to-head clinical studies are available. The aim of this manuscript is to review the published network meta-analysis (NMA) to gain a better understanding...

European Review » Rheumatology

Thu Feb 27, 2020 18:07

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Heavy metal orchestration

Nature Chemistry, Published online: 27 February 2020; doi:10.1038/s41557-020-0434-3Many current methods to prepare 2-hydroxybiaryls require the prefunctionalization of phenol groups or show limited substrate scope. Now, use of a pentavalent sulfone-bridged bismacycle, formed in situ by telescoped boron-to-bismuth transmetallation and oxidation, allows the direct and regioselective ortho-arylation of unprotected phenols.

Modular bismacycles for the selective C–H arylation of phenols and naphthols

Thu Feb 27, 2020 02:00

Nature Chemistry, Published online: 27 February 2020; doi:10.1038/s41557-020-0425-4Step-economic access to the biologically relevant 2-hydroxybiaryl motif represents a long-standing challenge in synthetic organic chemistry. Now, a bismuth-mediated oxidative arylation of phenols and naphthols with boronic acids has been developed — supported by experimental mechanistic insight — giving a direct and practical route to this valuable molecular architecture.

Thu Feb 27, 2020 02:00

RNA returns to the fold

Nature Chemistry, Published online: 27 February 2020; doi:10.1038/s41557-020-0432-5RNA has multiple roles in biology, enabled by its structural diversity. Now, artificially grafted RNA motifs have been encoded in a single RNA strand to form self-assembling nanostructures with controlled geometry and function.

Delving into dynamic effects

Thu Feb 27, 2020 02:00

Nature Chemistry, Published online: 27 February 2020; doi:10.1038/s41557-020-0435-2Although the application of force to induce chemical transformations is an active area of research, detailed understanding of these mechanochemical pathways is still lacking. Now, the mechanochemical activation of [4]-ladderane has been studied and found to exhibit unique non-equilibrium dynamic effects.

Joint PET-MRI Image Reconstruction using a Patch-Based Joint-Dictionary Prior

Thu Feb 27, 2020 02:00

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Medical Image Analysis

Publication date: Available online 27 February 2020Source: Medical Image AnalysisAuthor(s): Viswanath P. Sudarshan, Gary F. Egan, Zhaolin Chen, Suyash P. Awate

Medical Image Analysis

Thu Feb 27, 2020 18:01

Contrast Agent-free Synthesis and Segmentation of Ischemic Heart Disease Images using Progressive Sequential Causal GANs

Publication date: Available online 26 February 2020Source: Medical Image AnalysisAuthor(s): Chenchu Xu, Lei Xu, Pavlo Ohorodnyk, Mike Roth, Bo Chen, Shuo Li

Medical Image Analysis

Thu Feb 27, 2020 18:01

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Brain and Language

Cognitive control regions are recruited in bilinguals' silent reading of mixed-language paragraphs

Publication date: May 2020Source: Brain and Language, Volume 204Author(s): Alena Stasenko, Chelsea Hays, Christina E. Wierenga, Tamar H. Gollan

Brain and Language

Thu Feb 27, 2020 18:01

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ScienceDirect Publication: American Journal of Infection Control

Viral and bacterial coinfection among hospitalized children with respiratory tract infections

Publication date: Available online 26 February 2020Source: American Journal of Infection ControlAuthor(s): Junxiao Liu, Mengli Wang, Zhihong Zhao, Xiao Lin, Pei Zhang, Qingfen Yue, Ting Zhang, Yujuan Meng

ScienceDirect Publication: American Journal of Infection Control

Thu Feb 27, 2020 17:58

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ClinicalTrials

Phase I/II Trial of Combination Immunotherapy in Subjects With Advanced HPV Associated Malignancies

Conditions: Cervical Cancer; HPV Cancers; Anal Cancer; Oropharyngeal Cancer; Vulvar, Vaginal, Penile, Rectal CancerInterventions: Biological: PDS0101; Biological: M7824; Biological: NHS-IL12Sponsor: National Cancer Institute (NCI)Not yet recruiting

ClinicalTrials

Thu Feb 27, 2020 17:55

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ScienceDirect Publication: Journal of Bodywork and Movement Therapies

Sensory regulation and mechanical effects of sustained high intensity stretching of the anterior compartment of the thigh

Publication date: Available online 27 February 2020Source: Journal of Bodywork and Movement TherapiesAuthor(s): Frank Germain, Elodie Lemarchand, Raphael Perrin

ScienceDirect Publication: Journal of Bodywork and Movement Therapies

Thu Feb 27, 2020 17:50

The effectiveness of Biomechanical Taping and KinesioTaping on Shoulder pain, active range of motion and function of participants with Trapezius Myalgia: a randomized controlled trial

Publication date: Available online 27 February 2020Source: Journal of Bodywork and Movement TherapiesAuthor(s): Valentin III.C. Dones, Jocel M. Regino, Nicole Trizia S. Esplana, Ivan Rafael V. Rivera, Melissa Kaye R. Tomas

ScienceDirect Publication: Journal of Bodywork and Movement Therapies

Thu Feb 27, 2020 17:50

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Validation of High Precision Robot-Assisted Methods for Intracranial Applications: Preliminary Study

Publication date: May 2020Source: World Neurosurgery, Volume 137Author(s): Abhishek Kaushik, T.A. Dwarakanath, Gaurav Bhutani, Aliasgar Moiyadi, Pradip Chaudhari

Learning curve of robot-assisted percutaneous kyphoplasty for osteoporotic vertebral compression fractures

Thu Feb 27, 2020 17:41

Publication date: Available online 27 February 2020Source: World NeurosurgeryAuthor(s): Wei Yuan, Wenhai Cao, Xiaotong Meng, Haitao Zhu, Xinchun Liu, Cui Cui, Lin Tao, Yue Zhu

Carotid-carotid bypass for a carotid artery aneurysm

Thu Feb 27, 2020 17:41

Publication date: Available online 27 February 2020Source: World NeurosurgeryAuthor(s): Yoichi Morofuji, Yuki Matsunaga, Tsuyoshi Izumo

Admission neutrophil–lymphocyte ratio predicts rebleeding following aneurismal subarachnoid hemorrhage

Thu Feb 27, 2020 17:41

Publication date: Available online 27 February 2020Source: World NeurosurgeryAuthor(s): Jia-Yin Wang, Xin-Tong Zhang, Jian-Qun Wang, Chao-Ying Wang, Wan-Ling Zheng, Zhi-Ming Pan, Zhen-Bin Xu, Xiao-Yan Li, Yi-Bin Zhang

Full-Endoscopic Removal of Sheared Lumbar Epidural Catheter Fragment

Thu Feb 27, 2020 17:41

Publication date: Available online 27 February 2020Source: World NeurosurgeryAuthor(s): Naveen Davangere Siddappa, Jin-Sung Kim, Ashwinkumar Vasant Khandge

Should the Presence of Spondylodiscitis Alter the Surgical Treatment of Patients with Symptomatic Ventral Cervical Epidural Abscesses? An Institutional Analysis

Thu Feb 27, 2020 17:41

Publication date: Available online 26 February 2020Source: World NeurosurgeryAuthor(s): Daniel A. Tonetti, Bradley Eichar, William J. Ares, Adam S. Kanter, D. Kojo Hamilton

Thirty-day outcome of carotid artery stenting in elderly patients: a single center experience

Thu Feb 27, 2020 17:41

Publication date: Available online 26 February 2020Source: World NeurosurgeryAuthor(s): Yao Feng, Xuesong Bai, Shenmao Li, Fengshui Zhu, Yabing Wang, Yanfei Chen, Peng Gao, Bin Yang, Yang Hua, Jie Lu, Feng Ling, Yan Ma, Liqun Jiao

SCIENTIFIC CONTRIBUTIONS OF THE MEXICAN ASSOCIATION OF SPINE SURGEONS (ASOCIACIÓN MEXICANA DE CIRUJANOS DE COLUMNA- AMCICO) TO THE GLOBAL MEDICAL LITERATURE: A 21-YEAR SYSTEMATIC REVIEW

Thu Feb 27, 2020 17:41

Publication date: Available online 26 February 2020Source: World NeurosurgeryAuthor(s): José Antonio Soriano Sánchez, Sergio Soriano Solis, Manuel Eduardo Soto Garcia, José Alberto Israel Romero Rangel

Comparison of Minimally Invasive and Pterional Craniotomies for Ruptured Anterior Circulation Aneurysms: A Propensity Score-Matched Analysis

Thu Feb 27, 2020 17:41

Publication date: Available online 26 February 2020Source: World NeurosurgeryAuthor(s): Raywat Noiphithak, Vich Yindeedej, Warot Ratanavinitkul, Gahn Duangprasert, Dilok Tantongtip, Anusak Liengudom

Comparison of intraoperative CT with postoperative MRI for determining DBS electrode coordinates

Thu Feb 27, 2020 17:41

Publication date: Available online 26 February 2020Source: World NeurosurgeryAuthor(s): Fady Girgis, Hosniya Zarabi, Mena Said, Lin Zhang, Kiarash Shahlaie, Ignacio Saez

In Vivo Testing of a Prototype Intradural Spinal Cord Stimulator in a Porcine Model

Thu Feb 27, 2020 17:41

Publication date: Available online 26 February 2020Source: World NeurosurgeryAuthor(s): Marshall T. Holland, Scott C. Seaman, Royce W. Woodroffe, Douglas C. Fredericks, Christopher K. Kovach, Katherine N. Gibson-Corley, George T. Gillies, Matthew A. Howard

An intracranial aneurysm presenting robust metal artifact: a case report.

Thu Feb 27, 2020 17:41

Publication date: Available online 26 February 2020Source: World NeurosurgeryAuthor(s): Dingke Wen, Xuyang Liu, Hao Li, Lu Ma, Lingxiao Huang, Xinrui Yang, Nicholas W. Kieran, Chao You, Mu Yang