Publication date: Available online 26 February 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Xiaofei Fei, Chaoyang Li, Yun Zhang, Hongya Zhang, Xuewu Liu, Xinchao Ji, Yajun Shi, Na Liu, Mengli Wu, Fang Du, Yining Yang, Wen Dai, TingTing Liu, Ying He, Ting Bian, Huimin Zhou, Xingyue An, Zheng Cai, Jian Shi, Guodong Feng
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Related ArticlesUse of Combined Electroencephalography and Tilt Table Testing to Determine Etiology of Loss of Consciousness. Neurodiagn J. 2020 Mar;60(1):36-40 Authors: Singh N, Lynch T, Ritaccio A Abstract Tilt table testing is a common noninvasive diagnostic test performed to reproduce and evaluate syncope in a vulnerable patient and subsequently guide therapy. Electroencephalography (EEG) is typically useful for identifying interictal and ictal abnormalities...
Related ArticlesMedication Utilization Patterns 90 Days Before Initiation of Treatment with Repository Corticotropin Injection in Patients with Infantile Spasms. Pediatric Health Med Ther. 2019;10:195-207 Authors: Gold LS, Nazareth TA, Yu TC, Fry KR, Mahler NH, Rava A, Waltrip Ii RW, Hansen RN Abstract Introduction: Infantile spasms (IS) is a rare and devastating form of early childhood epilepsy. Two drugs are approved in the United States for treatment...
Related ArticlesmicroRNA-182 Negatively Influences the Neuroprotective Effect of Apelin Against Neuronal Injury in Epilepsy. Neuropsychiatr Dis Treat. 2020;16:327-338 Authors: Dong H, Dong B, Zhang N, Liu S, Zhao H Abstract Purpose: To explore the neuroprotective effects and mechanisms of Apelin (APLN), and to study the regulation of APLN expression by microRNA (miRNA) in epilepsy. Materials and Methods: In vitro and in vivo epileptic models...
Related ArticlesMetabolic Profiling of the Cerebrospinal Fluid in Pediatric Epilepsy. Acta Med Okayama. 2020 Feb;74(1):65-72 Authors: Akiyama T, Saigusa D, Hyodo Y, Umeda K, Saijo R, Koshiba S, Kobayashi K Abstract To characterize metabolic profiles within the central nervous system in epilepsy, we performed gas chromatography-tandem mass spectrometry (GC-MS/MS)-based metabolome analysis of the cerebrospinal fluid (CSF) in pediatric patients with and...
Related ArticlesROCK/PKA inhibition rescues hippocampal hyperexcitability and GABAergic neuron alterations in Oligophrenin-1 Knock-out mouse model of X-linked intellectual disability. J Neurosci. 2020 Feb 24;: Authors: Busti I, Allegra M, Spalletti C, Panzi C, Restani L, Billuart P, Caleo M Abstract Oligophrenin-1 (Ophn1) encodes a Rho GTPase activating protein whose mutations cause X-linked intellectual disability (XLID) in humans. Loss of function...
Related ArticlesDistinct Effects of Stereotactically Injected Human Cerebrospinal Fluid Containing Glutamic Acid Decarboxylase Antibodies into the Hippocampus of Rats on the Development of Spontaneous Epileptic Activity. Brain Sci. 2020 Feb 22;10(2): Authors: Frerker B, Rohde M, Müller S, Bien CG, Köhling R, Kirschstein T Abstract Background: The conversion of glutamic acid into γ-aminobutyric acid (GABA) is catalyzed by the glutamic acid decarboxylase...
Related ArticlesSevere neonatal hypoxic-ischaemic brain injury: still an important cause of infantile spasms. Dev Med Child Neurol. 2020 01;62(1):9 Authors: Vollmer B PMID: 31677161 [PubMed - indexed for MEDLINE]
Related ArticlesTaurine and its analogs in neurological disorders: Focus on therapeutic potential and molecular mechanisms. Redox Biol. 2019 06;24:101223 Authors: Jakaria M, Azam S, Haque ME, Jo SH, Uddin MS, Kim IS, Choi DK Abstract Taurine is a sulfur-containing amino acid and known as semi-essential in mammals and is produced chiefly by the liver and kidney. It presents in different organs, including retina, brain, heart and placenta and demonstrates...
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This study was carried out to identify and estimate physiological function of a new type of opsin subfamily present in the retina and whole brain tissues of Japanese eel using RNA–Seq transcriptome method. A total of 18 opsin subfamilies were identified through RNA–seq. The visual opsin family included Rh2, SWS2, FWO, DSO, and Exo-Rhod. The non-visual opsin family included four types of melanopsin subfamily (Opn4x1, Opn4x2, Opn4m1, and Opn4m2), peropsin, two types of neuropsin subfamily (Opn5-like,...
Background Microbiomes are extremely important for their host organisms, providing many vital functions and extending their hosts’ phenotypes. Natural studies of host-associated microbiomes can be difficult to interpret due to the high complexity of microbial communities, which hinders our ability to track and identify individual members along with the many factors that structure or perturb those communities. For this reason, researchers have turned to synthetic or constructed communities...
Purpose Several nephrometry scoring systems have been developed based on two-dimensional computerized tomography images to quantify anatomical features of renal tumors. We have developed an accurate three-dimensional nephrometry scoring system to respond to the urgent need for advanced systems based on three-dimensional images. Materials and Methods We retrospectively reviewed 135 patients who underwent partial nephrectomy...
The burden of vector-borne diseases (Dengue, Zika virus, yellow fever, etc.) gradually increased in the past decade across the globe. Mathematical modelling on infectious diseases helps to study the transmission dynamics of the pathogens. Theoretically, the diseases can be controlled and eventually eradicated by maintaining the effective reproduction number, ( ${\mathcal{R}}_{\mathrm{eff}}$ ...
In this study, four experimental assays were conducted to evaluate the use of a new silver nanoparticle formulation named Argovit-4, which was prepared with slight modifications to enhance its biological activity against white spot syndrome virus (WSSV) in shrimp culture. The goals of these assays were to (1) determine the protective effect of Argovit-4 against WSSV, (2) determine whether Argovit-4 supplemented in feed exhibits toxicity towards shrimp, (3) determine whether Argovit-4 as antiviral...
Background The Clarion-Clipperton Fracture Zone (CCFZ) in the Northeast Central Pacific Ocean is a region of heightened scientific and public interest because of its wealth in manganese nodules. Due to a poor ecological understanding at the abyssal seafloor and limited knowledge of the organisms inhabiting this area, huge efforts in alpha taxonomy are required. To predict and manage potential hazards associated with future mining, taxonomy is an essential first step to grasp fundamental ecosystem...
Background Promoting and maintaining health is critical to ruminant welfare and productivity. Within human medicine, faecal lactoferrin is quantified for routine assessment of various gastrointestinal illnesses avoiding the need for blood sampling. This approach might also be adapted and applied for non-invasive health assessments in animals. Methods In this proof-of-concept study, a bovine lactoferrin enzyme-linked immunosorbent assays (ELISA), designed for serum and milk, was applied...
Background Studies evaluating bacteria in insects can provide information about host–microorganism–environment interactions. The gut microbial community has a profound effect on different physiological functions of insects. Enterococcus spp. are part of the gut community in humans and other animals, as well as in insects. The presence and antimicrobial resistance profile of enterococci are well studied in different animals; however, data for Heliconius erato phyllis (Lepidoptera:...
Engineered nanoparticles are used at an increasing rate in both industry and medicine without fully understanding their impact on health and environment. The nematode Caenorhabditis elegans is a suitable model to study the toxic effects of nanoparticles as it is amenable to comprehensive phenotyping, such as locomotion, growth, neurotoxicity and reproduction. In this study, we systematically evaluated the effects of silver (Ag) and five metal oxide nanoparticles: SiO2, CeO2, CuO, Al2O3 and TiO2....
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Related ArticlesMeiotic block with roscovitine improves competence of porcine oocytes by fine-tuning activities of different cyclin-dependent kinases. J Cell Physiol. 2020 Feb 26;: Authors: Zhu S, Jia YJ, Pan LZ, Gong S, Sun MJ, Wang GL, Luo MJ, Tan JH Abstract Successful use of oocytes from small follicles (SFs) is of great importance for animal embryo production and human in vitro fertilization with reduced hormone-related side effects. How in vitro...
Related ArticlesLoss of p62 impairs bone turnover and inhibits PTH-induced osteogenesis. J Cell Physiol. 2020 Feb 26;: Authors: Agas D, Amaroli A, Lacava G, Yanagawa T, Sabbieti MG Abstract The p62 (also named sequestosome1/SQSTM1) is multidomain and multifunctional protein associated with several physiological and pathological conditions. A number of studies evidenced an involvement of p62 on the disruptive bone scenarios due to its participation in...
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Related ArticlesClinical and Dermoscopic Features Associated With Difficult-to-Recognize Variants of Cutaneous Melanoma: A Systematic Review. JAMA Dermatol. 2020 Feb 26;: Authors: Pampena R, Lai M, Lombardi M, Mirra M, Raucci M, Lallas A, Apalla Z, Argenziano G, Pellacani G, Longo C Abstract Importance: The clinical and dermoscopic features of the vast majority of uncommon variants of cutaneous melanoma have been rarely reported, leading to difficulty...
Related ArticlesSalvage carbon ion radiotherapy for recurrent solitary fibrous tumor: A case report and literature review. J Orthop Surg (Hong Kong). 2020 Jan-Apr;28(1):2309499019896099 Authors: Murata K, Endo K, Aihara T, Matsuoka Y, Nishimura H, Suzuki H, Sawaji Y, Yamamoto K, Fukami S, Tanigawa M, Matsubayashi J, Nagao T, Imai R Abstract BACKGROUND: Malignant solitary fibrous tumor (MSFT) arising from the spinal cord is extremely rare and poorly understood...
Related ArticlesDual-molecular barcode sequencing detects rare variants in tumor and cell free DNA in plasma. Sci Rep. 2020 Feb 25;10(1):3391 Authors: Hirotsu Y, Otake S, Ohyama H, Amemiya K, Higuchi R, Oyama T, Mochizuki H, Goto T, Omata M Abstract Conventional next generation sequencing analysis has provided important insights into cancer genetics. However, the detection of rare (low allele fraction) variants remains difficult because of the error-prone...
Related ArticlesGastrointestinal stromal tumour of stomach: Feasibility of laparoscopic resection in large lesions and its long-term outcomes. J Minim Access Surg. 2020 Feb 26;: Authors: Parthasarathi, Dhawal S, Chittawadagi B, Cumar B, Kumar S, Palanivelu C Abstract Background: Gastric gastrointestinal stromal tumours (GISTs) are rare neoplasms that require excision for cure. Although the feasibility of laparoscopic resection of smaller gastric GIST...
Laparoscopic adrenalectomy for giant adrenal tumours: Technical considerations and surgical outcome.
Related ArticlesLaparoscopic adrenalectomy for giant adrenal tumours: Technical considerations and surgical outcome. J Minim Access Surg. 2020 Feb 26;: Authors: Giordano A, Alemanno G, Bergamini C, Valeri A, Prosperi P Abstract Background: Giant adrenal tumours are tumours with size ≥6 cm. These are rare cancer associated with malignancy in 25% of cases. Patients and Methods: A retrospective review was conducted on the medical records of patients...
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