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Τετάρτη 26 Φεβρουαρίου 2020


Indian clinical practice consensus guidelines for the management of squamous cell carcinoma of head and neck
Kumar Prabhash, Govind Babu, Pankaj Chaturvedi, Moni Kuriakose, Praveen Birur, Anil K Anand, Ashish Kaushal, Abhishek Mahajan, Judita Syiemlieh, Manish Singhal, Munish Gairola, Prakash Ramachandra, Sumit Goyal, Subashini John, Rohit Nayyar, Vijay M Patil, Vishal Rao, Vikas Roshan, GK RathIndian Journal of Cancer 2020 57(5):1-5 Head and neck cancers (HNCs) are malignant tumors of the upper aerodigestive tract and are the sixth most common cancer worldwide. In India, around 30–40% of all cancers...
Indian Journal of Cancer : 2014 - 51(1)
Tue Feb 25, 2020 00:00
Indian clinical practice consensus guidelines for the management of nasopharyngeal cancer
Munish Gairola, Kumar Prabhash, Govind Babu, Pankaj Chaturvedi, Moni Kuriakose, Praveen Birur, Anil K Anand, Ashish Kaushal, Abhishek Mahajan, Judita Syiemlieh, Manish Singhal, Prakash Ramachandra, Sumit Goyal, Subashini John, Rohit Nayyar, Vijay M Patil, Vishal Rao, Vikas Roshan, GK RathIndian Journal of Cancer 2020 57(5):9-11
Indian Journal of Cancer : 2014 - 51(1)
Tue Feb 25, 2020 00:00
Appendix 3: Summary of clinical evidences in Locally Advanced disease (Head and Neck cancer)
. Indian Journal of Cancer 2020 57(5):43-46
Indian Journal of Cancer : 2014 - 51(1)
Tue Feb 25, 2020 00:00
Indian clinical practice consensus guidelines for the management of oropharyngeal cancer
Kumar Prabhash, Govind Babu, Pankaj Chaturvedi, Moni Kuriakose, Praveen Birur, Anil K Anand, Ashish Kaushal, Abhishek Mahajan, Judita Syiemlieh, Manish Singhal, Munish Gairola, Prakash Ramachandra, Sumit Goyal, Subashini John, Rohit Nayyar, Vijay M Patil, Vishal Rao, Vikas Roshan, GK RathIndian Journal of Cancer 2020 57(5):12-15
Indian Journal of Cancer : 2014 - 51(1)
Tue Feb 25, 2020 00:00
Indian clinical practice consensus guidelines for the management of very advanced disease of squamous cell carcinoma of head and neck
Kumar Prabhash, Govind Babu, Pankaj Chaturvedi, Moni Kuriakose, Praveen Birur, Anil K Anand, Ashish Kaushal, Abhishek Mahajan, Judita Syiemlieh, Manish Singhal, Munish Gairola, Prakash Ramachandra, Sumit Goyal, Subashini John, Rohit Nayyar, Vijay M Patil, Vishal Rao, Vikas Roshan, Rath G KIndian Journal of Cancer 2020 57(5):22-25
Indian Journal of Cancer : 2014 - 51(1)
Tue Feb 25, 2020 00:00
Indian clinical practice consensus guidelines for the management of hypopharyngeal cancer
Govind Babu, Kumar Prabhash, Pankaj Chaturvedi, Moni Kuriakose, Praveen Birur, Anil K Anand, Ashish Kaushal, Abhishek Mahajan, Judita Syiemlieh, Manish Singhal, Munish Gairola, Prakash Ramachandra, Sumit Goyal, Subashini John, Rohit Nayyar, Vijay M Patil, Vishal Rao, Vikas Roshan, GK RathIndian Journal of Cancer 2020 57(5):16-18
Indian Journal of Cancer : 2014 - 51(1)
Tue Feb 25, 2020 00:00
Appendix 2: Summary of clinical evidences in nasopharyngeal cancer
. Indian Journal of Cancer 2020 57(5):37-42
Indian Journal of Cancer : 2014 - 51(1)
Tue Feb 25, 2020 00:00
Indian clinical practice consensus guidelines for the management of laryngeal cancer
Manish Singhal, Kumar Prabhash, Govind Babu, Pankaj Chaturvedi, Moni Kuriakose, Praveen Birur, Anil K Anand, Ashish Kaushal, Abhishek Mahajan, Judita Syiemlieh, Munish Gairola, Prakash Ramachandra, Sumit Goyal, Subashini John, Rohit Nayyar, Vijay M Patil, Vishal Rao, Vikas Roshan, GK RathIndian Journal of Cancer 2020 57(5):19-21
Indian Journal of Cancer : 2014 - 51(1)
Tue Feb 25, 2020 00:00
Appendix 4: Summary of clinical evidences in Recurrent and/or Metastatic disease (Head and Neck Cancer)
. Indian Journal of Cancer 2020 57(5):47-53
Indian Journal of Cancer : 2014 - 51(1)
Tue Feb 25, 2020 00:00
Use of a K-nearest neighbors model to predict the development of type 2 diabetes within 2 years in an obese, hypertensive population
Abstract Prediabetes is a type of hyperglycemia in which patients have blood glucose levels above normal but below the threshold for type 2 diabetes mellitus (T2DM). Prediabetic patients are considered to be at high risk for developing T2DM, but not all will eventually do so. Because it is difficult to identify which patients have an increased risk of developing T2DM, we developed a model of several clinical and laboratory features to predict the development of T2DM within a 2-year...
Latest Results for Medical
02:00
Thyroid Nodules and Real Estate: Location Matters
Thyroid, Ahead of Print.
liebertpub1
Tue Feb 25, 2020 10:00
Patient Age Is an Independent Risk Factor of Relapse of Differentiated Thyroid Carcinoma and Improves the Performance of the American Thyroid Association Stratification System
Thyroid, Ahead of Print.
liebertpub1
Tue Feb 25, 2020 10:00
In vitro simultaneous mapping of the partial pressure of oxygen, pH and inorganic phosphate using electron paramagnetic resonance
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00168F, PaperAkihiro Taguchi, Stephen DeVience, Benoit Driesschaert, Valery V Khramtsov, Hiroshi HirataThe partial pressure of oxygen (pO2) and the extracellular pH in the tumour microenvironment are essential parameters for understanding the physiological state of a solid tumour. Also, phosphate-containing metabolites are...The content of this RSS Feed (c) The Royal Society of Chemistry
Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)
02:00
Highly sensitive and adjustable colorimetric assay of hydrogen sulfide by signal amplification based on G-quadruplex-Cu2+ peroxidase mimetics
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00093K, Paperyu Ma, Maotian Xu, Yongxiang Wang, Zi Liu, Baoxian YeThis work reports the first example of a colorimetric H2S sensor through constructing G-quadruplex-Cu2+ peroxidase mimetics (G4-Cu2+) employing Cu2+ ions and G-rich DNA with signal amplification. In the hydrogen peroxide...The content of this RSS Feed (c) The Royal Society of Chemistry
Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)
02:00
Precision medicine, bioanalytics and nanomaterials: toward new generation of personalized portable diagnostics
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/C9AN02041A, Critical ReviewMaria Maddalena Calabretta, Martina Zangheri, Antonia Lopreside, Elisa Marchegiani, Laura Montali, Patrizia Simoni, Aldo RodaThe customization of disease treatment focused on genetic, environmental and lifestyle factors of the individual patients, including tailored medical decisions and treatments, is identified as precision medicine. This approach involves...The content of this RSS Feed (c) The Royal Society of Chemistry
Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)
Tue Feb 25, 2020 02:00
Assessment of Prognosis in Odontogenic Descending Necrotizing Mediastinitis: A Longitudinal Retrospective Study
Surgical Infections, Ahead of Print.
Surgical Infections
Tue Feb 25, 2020 10:00
Immediate Closure of Abdominal Cavity with Biologic Mesh versus Temporary Abdominal Closure of Open Abdomen in Non-Trauma Emergency Patients (CLOSE-UP Study)
Surgical Infections, Ahead of Print.
Surgical Infections
Tue Feb 25, 2020 10:00
Anesthesia Procedure of Emergency Operation for Patients with Suspected or Confirmed COVID-19
Surgical Infections, Ahead of Print.
Surgical Infections
Tue Feb 25, 2020 10:00
Polycistronic Delivery of IL-10 and NT-3 Promotes Oligodendrocyte Myelination and Functional Recovery in a Mouse Spinal Cord Injury Model
Tissue Engineering Part A, Ahead of Print.
Tissue Engineering
Tue Feb 25, 2020 10:00
Fluid–Structure Coupling Model and Experimental Validation of Interaction Between Pneumatic Soft Actuator and Lower Limb
Soft Robotics, Ahead of Print.
Soft Robotics
Tue Feb 25, 2020 10:00
Octopus Arm-Inspired Tapered Soft Actuators with Suckers for Improved Grasping
Soft Robotics, Ahead of Print.
Soft Robotics
Tue Feb 25, 2020 10:00
Orthologous promoters from related methylotrophic yeasts surpass expression of endogenous promoters of Pichia pastoris
Methylotrophic yeasts such as Komagataella phaffii (syn. Pichia pastoris, Pp), Hansenula polymorpha (Hp), Candida boidinii (Cb) and Pichia methanolica (Pm) are widely used protein production platforms. Typically,...
Applied and Industrial Microbiology
Tue Feb 25, 2020 02:00
Decreased expression of LRA4, a key gene involved in rhamnose metabolism, caused up-regulated expression of the genes in this pathway and autophagy in Pichia pastoris
In a previous study, we developed Pichia pastoris GS115m, an engineered strain with decreased expression of one key gene, LRA4, in rhamnose metabolism. P. pastoris GS115m/LacB was subsequently constructed via int...
Applied and Industrial Microbiology
Tue Feb 25, 2020 02:00
Statistical Cerebrovascular Reactivity Signal Properties after Secondary Decompressive Craniectomy in Traumatic Brain Injury: A CENTER-TBI Pilot Analysis
Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma
Tue Feb 25, 2020 10:00
Common Data Elements: Critical Assessment of Harmonization between Current Multi-Center Traumatic Brain Injury Studies
Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma
Tue Feb 25, 2020 10:00
Acute and Persistent Alterations of Cerebellar Inflammatory Networks and Glial Activation in a Rat Model of Pediatric Mild Traumatic Brain Injury
Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma
Tue Feb 25, 2020 10:00
Prognostic Validation of the NINDS Common Data Elements for the Radiologic Reporting of Acute Traumatic Brain Injuries: A CENTER-TBI Study
Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma
Tue Feb 25, 2020 10:00
Against Philosophical Anarchism
Abstract Philosophical anarchists claim that all states lack political authority and are illegitimate, but that some states are nevertheless morally justified and should not be abolished. I argue that philosophical anarchism is either incoherent or collapses into either statism or political anarchism.
Latest Results for Law and Philosophy
02:00
Phonak Marvel Now Available on Custom and BTE Hearing Aids
Phonak's award-winning Marvel technology is now available on custom in-the-ear (ITE), super-power, and pediatric hearing aids across multiple performance levels. Over 2 million ears now benefit from the sound performance and connectivity offered by Marvel technology since its release in October 2018. Marvel connectivity features hand-free calls and audio streaming to virtually any Bluetooth enabled devices like smartphones, tablets, computers, or TVs.Earlier this year at the 2020 International CES,...
Audiology
Tue Feb 25, 2020 14:41
Clinical Presentations and Comparative Outcomes of Delayed-Onset Low-Grade Endophthalmitis Managed with or Without Intraocular Lens Explantation
Clinical Ophthalmology
04:49
Two Year Visual Acuity and Structural Outcomes in Patients with Diabetic Macular Oedema Treated with Intravitreal Aflibercept – A Retrospective Cohort Study
Clinical Ophthalmology
04:46
Anesthesia for Intravitreal Injection: A Systematic Review
Clinical Ophthalmology
04:42
Draft Genome Assembly of Floccularia luteovirens, an Edible and Symbiotic Mushroom on Qinghai-Tibet Plateau
Floccularia luteovirens, also known as "Yellow mushroom", is an edible ectomycorrhizal fungus widely distributed in the Qinghai-Tibet Plateau alpine meadow. So far, little genomic information is known about F. luteovirens, which is not conductive to the protection and utilization of it. In this manuscript, we present a first draft genome assembly and annotation of F. luteovirens. The fruiting body of F. luteovirens was sequenced with PacBio Sequel and Illumina Hiseq 2500 system. The assembled genome...
G3: .Genes, Genomes, Genetics Mission - Online First Articles
Tue Feb 25, 2020 23:55
Induced tumor heterogeneity reveals factors informing radiation and immunotherapy combinations
Purpose: To investigate how induced tumor heterogeneity influences immune responses to radiotherapy (RT) with different proportions of mixed immune responsive and unresponsive tumor cells in a triple negative breast cancer model. It is hypothesized that studying the immune environment of mixed tumors and responses to RT could nominate immune active therapies to enhance immune responses after RT. Experimental Design: Evaluate efficacy and immune responses generated by RT in tumors with different...
Clinical Cancer Research Online First Articles
Tue Feb 25, 2020 16:34
Long-term consequences of pelvic irradiation: toxicities, challenges and therapeutic opportunities with pharmacologic mitigators
A percentage of long-term cancer survivors who receive pelvic irradiation will develop treatment related late effects, collectively termed pelvic radiation disease. Thus, there is a need to prevent or ameliorate treatment related late effects in these patients. Modern radiotherapy methods can preferentially protect normal tissues from radiation toxicities to permit higher doses to targets. However, concerns about chronic small bowel toxicity, for example, still constrain the prescription dose. This...
Clinical Cancer Research Online First Articles
Tue Feb 25, 2020 16:34
Anastrozole has an association between degree of estrogen suppression and outcomes in early breast cancer and is a ligand for estrogen receptor {alpha}
Purpose:To determine if the degree of estrogen suppression with aromatase inhibitors (AIs: anastrozole, exemestane, letrozole) is associated with efficacy in early stage breast cancer, and to examine for differences in the mechanism of action between the three AIs. Experimental Design:Matched case-control studies [247 matched sets from MA.27 (anastrozole vs. exemestane) and PreFace (letrozole) trials] were undertaken to assess whether estrone or estradiol concentrations after six months of adjuvant...
Clinical Cancer Research Online First Articles
Tue Feb 25, 2020 16:34
Discovery of berberine that targetedly induce autophagic degradation of both BCR-ABL and BCR-ABL T315I through recruiting LRSAM1 for overcoming imatinib-resistance
Purpose: Imatinib, the breakpoint cluster region protein (BCR)/Abelson murine leukemia viral oncogene homolog (ABL) inhibitor, is widely used to treat chronic myeloid leukemia (CML). However, imatinib resistance develops in many patients. Therefore, new drugs with improved therapeutic effects are urgently needed. Berberine (BBR) is a potent BCR-ABL inhibitor for imatinib-sensitive and -resistant CML. Experimental Design: Protein structure analysis and virtual screening were used to identify BBR...
Clinical Cancer Research Online First Articles
Tue Feb 25, 2020 16:34
Phylogenetic and ontogenetic changes of the anatomical organization and modularity in the skull of archosaurs [NEW RESULTS]
Comparative anatomy studies of the skull of archosaurs provide insights on the mechanisms of evolution for the morphologically and functionally diverse species of crocodiles and birds. One of the key attributes of skull evolution is the anatomical changes associated with the physical arrangement of cranial bones. Here, we compare the changes in anatomical organization and modularity of the skull of extinct and extant archosaurs using an Anatomical Network Analysis approach. We show that the number...
bioRxiv Subject Collection: Evolutionary Biology
Tue Feb 25, 2020 02:00
Evolution of the standard genetic code [NEW RESULTS]
A near-universal Standard Genetic Code (SGC) implies a single origin for Earthly life. To study this unique event, I compute paths to the SGC, comparing different histories. SGC-like coding tables emerge, using traditional evolutionary mechanisms - a superior evolutionary route can be identified. To objectively measure evolution, progress values from 0 (random coding) to 1 (SGC-like) are defined, measuring fractions of random-code-to-SGC distance. Progress types are spacing/distance/delta Polar Requirement,...
bioRxiv Subject Collection: Evolutionary Biology
Tue Feb 25, 2020 02:00

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