Mark Farrenburg, Harsh V GuptaAnnals of Indian Academy of Neurology 2020 23(2):211-214 Background: Chorea is one of the disabling movement disorders, and the number of drugs which can treat this disorder effectively is limited. Tetrabenazine and deutetrabenazine are the two drugs approved by the US-FDA for the treatment of chorea associated with HD. Levodopa can improve chorea in some disorders, and this review aims to provide information on the use of levodopa in chorea. Methods: A literature...
Wed Feb 26, 2020 00:00
Nishanth Dev, Rahul Kumar, Ashok Kumawat, Mithu BhowmickAnnals of Indian Academy of Neurology 2020 23(2):237-238
Wed Feb 26, 2020 00:00
Kameshwar PrasadAnnals of Indian Academy of Neurology 2020 23(2):150-150
Wed Feb 26, 2020 00:00
Arpit Koolwal, Supriya Agrawal, Ghanshyam Das Koolwal, Kaveri Saxena, Ankit DaralAnnals of Indian Academy of Neurology 2020 23(2):225-227 Anti-NMDAR encephalitis is an autoimmune encephalitis with a typical clinical progression. Patients can often present to psychiatric outpatient departments (OPDs) mimicking psychiatric illnesses. In this case series, we have described two cases of adolescent age group that were eventually diagnosed with anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis....
Wed Feb 26, 2020 00:00
Apoorva PauranikAnnals of Indian Academy of Neurology 2020 23(2):151-152
Wed Feb 26, 2020 00:00
Anupriya Arthur, Ajith Sivadasan, Pavitra Mannam, AT Prabakhar, Sanjith Aaron, Vivek Mathew, M Karthik, Rohith Ninan Benjamin, Shaikh Atif Iqbalahmed, Gideon Lyngsyun Rynjah, Mathew AlexanderAnnals of Indian Academy of Neurology 2020 23(2):201-205 Background: Tolosa-Hunt Syndrome (THS) is one of the causes of cavernous sinus syndrome causing painful ophthalmoplegia. Literature on long-term outcome of this rare condition is scarce. Aims and Objectives: The aim is to study the recurrence and role...
Wed Feb 26, 2020 00:00
Anjali Chouksey, Sanjay PandeyAnnals of Indian Academy of Neurology 2020 23(2):153-154
Wed Feb 26, 2020 00:00
Lidiia N Prakhova, Aleksandr G Ilves, Svetlana N Kizhlo, Zhanna I SavintsevaAnnals of Indian Academy of Neurology 2020 23(2):220-222 For the first time, human immunodeficiency virus (HIV)-associated vacuolar myelopathy (VM) was detailed in an autopsy-based study of 89 cases in 1985. This condition is the most common cause for spinal cord lesions in HIV patients. VM's pathogenic mechanism remains unclear; however, it is assumed that the disease can be related to both, the direct neurotoxic impact...
Wed Feb 26, 2020 00:00
Benjamin Y. Q. Tan, Prakash R Paliwal, Vijay K SharmaAnnals of Indian Academy of Neurology 2020 23(2):155-158 Ischemic stroke remains a significant health problem, which is expected to increase owing to an aging population. A considerable proportion of stroke patients suffer from gastrointestinal complications, including dysphagia, gastrointestinal hemorrhage, and constipation. Often, these complications adversely affect stroke outcomes. Recent research postulates the role of “brain-gut axis”...
Wed Feb 26, 2020 00:00
Jong-Geun Seo, Sung-Pa ParkAnnals of Indian Academy of Neurology 2020 23(2):233-235
Wed Feb 26, 2020 00:00
Aastha Takkar, Vivek LalAnnals of Indian Academy of Neurology 2020 23(2):159-166 Idiopathic intracranial hypertension (IIH) is defined as a syndrome of raised intracranial pressure with normal imaging of the brain and cerebrospinal fluid (CSF) composition. There are many controversies and myths that surround IIH. Although patients of IIH may present “typical” symptoms and signs of raised intracranial pressure, clinical scenarios often vary. A typical clinical and radiological finding poses significant...
Wed Feb 26, 2020 00:00
Piyush Ranjan, Rajeev Ranjan, Mukul KumarAnnals of Indian Academy of Neurology 2020 23(2):145-149 Medical education in India is expected to undergo a significant reform after the introduction of the National Medical Commission Act. Single, nationwide National Exit Test (NEXT) is an essential provision under this act, which will be implemented during the next three years. It aims to bring about uniformity in the minimum standard of final MBBS examination, quality control in the licentiate examination...
Wed Feb 26, 2020 00:00
Ruma Madhu Sreedharan, Chandrasekharan Kesavadas, Subramonium Aiyappan, KM Anila, Amitha C Mohan, Sanjeev V ThomasAnnals of Indian Academy of Neurology 2020 23(2):167-173 Purpose: Children of women with epilepsy and antenatal antiepileptic drug (AED) exposure have increased risk of language dysfunction. Our objective was to compare language related functional MRI network connectivity (FC) of children with women with epilepsy with antenatal AED exposure (CAED) with that of healthy children (COAED)...
Wed Feb 26, 2020 00:00
Semra Gursoy, Esra Ataman, Bahar Toklu Baysal, Berk Özyılmaz, Pınar Gençpınar, Ayşe Semra Hız, Uluç Yiş, Aycan Ünalp, Nihal Olgaç Dündar, Ayfer Ülgenalp, Derya ErçalAnnals of Indian Academy of Neurology 2020 23(2):206-210 Background and Aims:PCDH19 gene, which encodes protocadherin 19, is associated with epilepsy and intellectual disability, mainly in affected females. The clinical manifestations are heterogeneous and the main features include early onset seizure, generalized or focal seizures...
Wed Feb 26, 2020 00:00
Jacob JoeAnnals of Indian Academy of Neurology 2020 23(2):174-176 Background: Levosulpiride (LS) is a prokinetic drug increasingly used for the gastric motility disorders. Despite its common use for the gastric motility disorder, the tendency to cause parkinsonism and acute dystonias are under-recognized as the major adverse effects. This study was aimed to evaluate the adverse effects of this drug in patients attending neurology clinics. Methods: Patients presenting with new-onset extrapyramidal...
Wed Feb 26, 2020 00:00
Deepthi Vemuri, Butchi Raju Garuda, S Gopi, T Sateesh Kumar, U Aruna KumariAnnals of Indian Academy of Neurology 2020 23(2):215-219 Background: Myasthenia gravis (MG) is an autoimmune disorder with a chronic fluctuating course. The outcome measures encapsulate disease severity, functional impact at diagnosis, and objective evaluation of clinical benefit from therapeutic interventions.Aims and Objective: To assess the disease severity, correlation between various outcome measures, and to evaluate...
Wed Feb 26, 2020 00:00
Juhi Gupta, Suvasini Sharma, Sharmila B Mukherjee, Puneet Jain, Satinder AnejaAnnals of Indian Academy of Neurology 2020 23(2):177-181 Objectives: To assess the neurodevelopmental outcome of West syndrome (WS) in Indian children, who differ in their clinical profile from the western population. Materials and Methods: This cross-sectional study enrolled children aged 2--5 years with prior diagnosis of WS between November 2013 and March 2015. They were assessed for epilepsy outcome and developmental...
Wed Feb 26, 2020 00:00
Harsh V Gupta, Heather Barnes, Fatma A Radhi, Yasir JassamAnnals of Indian Academy of Neurology 2020 23(2):223-224 Subacute onset of a mixed movement disorder should alert the clinician to the possibility of an autoimmune or paraneoplastic cause of symptoms. Striational antibodies have been associated with myasthenia gravis but a mixed movement disorder has been rarely reported with this antibody. We report a 90-year-old female who presented with generalized chorea, blepharospasm, and parkinsonism....
Wed Feb 26, 2020 00:00
Saurabh Bansal, Ramandeep Bansal, Manoj Kumar Goyal, Aastha Takkar, Ramandeep Singh, Paramjeet Singh, Vivek LalAnnals of Indian Academy of Neurology 2020 23(2):182-188 Background: Although first described more than two decades ago, posterior reversible encephalopathy syndrome (PRES) continues to be enigmatic. We prospectively followed consecutive patients of PRES both clinically and radiologically for a better understanding of natural history, symptomatology, and prognosis of this not so uncommon...
Wed Feb 26, 2020 00:00
Vesna D Stojanovic, Tanja D Radovanović, Katarina M Koprivšek, Gordana V Vijatov Ðurić, Aleksandra D DoronjskiAnnals of Indian Academy of Neurology 2020 23(2):228-232 We report a case of a 7-year-old boy with Kawasaki disease (KD) complicated with cerebral vasculitis and encephalitis. The patient was admitted with signs of encephalopathy, seizures, and coma. The diagnosis of KD was made on the 2nd day of hospitalization based on the clinical features (fever >5 days, maculopapular rash, nonpurulent...
Wed Feb 26, 2020 00:00
Arvind Sharma, Vijay K Sharma, Aftab Ahmad, Deepak Gupta, Khursheed Khan, Ashfaq Shuaib, Andrei V Alexandrov, Maher SaqqurAnnals of Indian Academy of Neurology 2020 23(2):189-194 Background and Aims: Despite the evidence from randomized clinical trials, the effectiveness of intravenous tissue recombinant plasminogen activator (IV-tPA) for elderly patients (≥80 yrs) with acute ischemic stroke (AIS) is often an important consideration in clinical practice. We evaluated the effect of older age on...
Wed Feb 26, 2020 00:00
Harsh V Gupta, Kayla Karlowski, Thomas J WhittakerAnnals of Indian Academy of Neurology 2020 23(2):235-237
Wed Feb 26, 2020 00:00
Zakir Hussain, Adreesh Mukherjee, Goutam Ganguly, Anindita Joardar, Sarnava Roy, Deb Sankar Guin, Uma Sinharoy, Atanu Biswas, Shyamal Kumar DasAnnals of Indian Academy of Neurology 2020 23(2):195-200 Background and Aims: To study the clinical profile of genetically proven Huntington's disease (HD) patients from eastern India. Methods: This cross sectional study selected patients of HD after genetic confirmation of expanded CAG repeats in Huntingtin (HTT) gene. We performed detail clinical evaluation...
Wed Feb 26, 2020 00:00
Shivan Kesavan, Bhanudeep Singanamalla, Dangudubiyyam Sri Krishna Sahitya, Arushi Gahlot Saini, Sameer VyasAnnals of Indian Academy of Neurology 2020 23(2):239-241
Wed Feb 26, 2020 00:00
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No abstract available
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Background: Patient-reported lower satisfaction with the abdomen preoperatively is a strong predictor of undergoing DIEP flap surgery. The authors evaluated physical well-being of the abdomen before and after flap-based breast reconstruction to determine potential predictors for decreased postoperative abdominal well-being. Methods: The authors retrospectively analyzed an institutional breast reconstruction registry, selecting patients who underwent abdominally based autologous flap breast...
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Background: The year 2017 marked the first year women comprised a majority of U.S. medical school matriculants. While more women are pursuing surgical training, within plastic surgery, there is a steady attrition of women advancing in leadership roles. The authors report the current status of women in academic plastic surgery, from trainees to chairwomen and national leadership positions. Methods: The Electronic Residency Applications Service, San Francisco Match, National Resident Matching...
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Background: Enhanced recovery after surgery (ERAS) initiatives improve postoperative function and expedite recovery, leading to a decrease in length of stay. The authors noted a high rate of postoperative symptomatic hypotension in patients undergoing abdominal free flap breast reconstruction and wished to explore this observation. Methods: Subjects undergoing abdominal free flap breast reconstruction at the authors’ institution from 2013 to 2017 were identified. The ERAS protocol was initiated...
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Summary: Reconstruction of substantial-sized upper lip defects may require an Abbe flap reconstruction to avoid excessive tightness and deformity. The design of the Abbe or lip switch flap harvested from the lower lip is important for a satisfactory aesthetic and functional result. Harvest of the flap is performed to enable a definitive inset into the defect. The video that accompanies this article depicts rotation of an Abbe flap into a philtral defect created by basal cell carcinoma excision.
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No abstract available
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No abstract available
04:16
Background: Prepectoral implant-based reconstruction reemerged as a viable approach following recent advances in reconstructive techniques and technology. To achieve successful outcomes, careful patient selection is critical. Obesity increases the risk of complications and has been suggested as a relative contraindication for prepectoral breast reconstruction. Methods: Retrospective chart review of patients who underwent immediate two-stage implant-based reconstruction at the authors’ institution...
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No abstract available
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Learning Objectives: After reviewing this article, the participant should be able to: 1. Start early protected movement at 3 to 5 days after surgery with relative motion extension splinting for zone 5 extensor tendon lacerations over the hand. 2. Allow patients to resume regular activities much sooner than the conventional 3 to 4 weeks of splinting after extensor tendon repair. 3. Improve the rehabilitation of boutonniere deformities with relative motion splinting. Summary: This article focuses...
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Background: The authors’ purpose was to evaluate the effects of body mass index, as defined by World Health Organization criteria, on complications and patient-reported outcomes in implant-based and autologous breast reconstruction. Methods: Complications and BREAST-Q patient-reported outcomes were analyzed 2 years after breast reconstruction for women from 11 participating sites. Separate mixed-effects regressions were performed to assess body mass index effects on outcomes. Results: ...
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Background: After breast reconstruction, nipple position and other long-term changes in the reconstructed breast relative to the contralateral breast remain poorly understood. In this prospective cohort study, the authors performed serial nipple position measurements over 5 years in patients who had undergone breast reconstruction with a transverse rectus abdominis musculocutaneous (TRAM) flap. The effects of adjuvant radiotherapy on nipple position over time were also investigated. Methods:...
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