IJERPH, Vol. 17, Pages 1355: Entrepreneurs and Environmental Sustainability in the Digital Era: Regional and Institutional Perspectives International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17041355 Authors: Ye Zhou Anwar Siddiquei Asmi Climate change and environmental degradation have negatively affected the sustainable development of mankind. The “green” concept has been gradually accepted by the public, thereby strongly...
Thu Feb 20, 2020 02:00
IJERPH, Vol. 17, Pages 1353: Participatory Environmentally Friendly Message Design: Influence of Message Features and User Characteristics International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17041353 Authors: Annie W. Y. Ng Alan H. S. Chan Labels and declarations are one of the tools of environmental management aimed at improving human behavior with regard to the environment. The development process of environmental labels and declarations has been...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1460: Homeostasis Imbalance of Microglia and Astrocytes Leads to Alteration in the Metabolites of the Kynurenine Pathway in LPS-Induced Depressive-Like Mice International Journal of Molecular Sciences doi: 10.3390/ijms21041460 Authors: Xue Tao Mingzhu Yan Lisha Wang Yunfeng Zhou Zhi Wang Tianji Xia Xinmin Liu Ruile Pan Qi Chang In the pathology-oriented study of depression, inflammation hypothesis has received increasing attention for recent...
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IJMS, Vol. 21, Pages 1459: Cathepsin B-associated Activation of Amyloidogenic Pathway in Murine Mucopolysaccharidosis Type I Brain Cortex International Journal of Molecular Sciences doi: 10.3390/ijms21041459 Authors: Gustavo Monteiro Viana Esteban Alberto Gonzalez Marcela Maciel Palacio Alvarez Renan Pelluzzi Cavalheiro Cinthia Castro do Nascimento Guilherme Baldo Vânia D’Almeida Marcelo Andrade de Lima Alexey V. Pshezhetsky Helena Bonciani Nader Mucopolysaccharidosis...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1458: EbARC1, an E3 Ubiquitin Ligase Gene in Erigeron breviscapus, Confers Self-Incompatibility in Transgenic Arabidopsis thaliana International Journal of Molecular Sciences doi: 10.3390/ijms21041458 Authors: Mo Chen Wei Fan Bing Hao Wei Zhang Mi Yan Yan Zhao Yanli Liang Guanze Liu Yingchun Lu Guanghui Zhang Zheng Zhao Yanru Hu Shengchao Yang Erigeron breviscapus (Vant.) Hand.-Mazz. is a famous traditional Chinese medicine that...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1457: Analysis of Non-Structural Carbohydrates and Xylem Anatomy of Leaf Petioles Offers New Insights in the Drought Response of Two Grapevine Cultivars International Journal of Molecular Sciences doi: 10.3390/ijms21041457 Authors: Rachele Falchi Elisa Petrussa Enrico Braidot Paolo Sivilotti Francesco Boscutti Marco Vuerich Carla Calligaro Antonio Filippi José Carlos Herrera Paolo Sabbatini Marco Zancani Andrea Nardini Enrico Peterlunger...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1452: Hyperbaric Oxygen Therapy Improves the Osteogenic and Vasculogenic Properties of Mesenchymal Stem Cells in the Presence of Inflammation In Vitro International Journal of Molecular Sciences doi: 10.3390/ijms21041452 Authors: Chiara Gardin Gerardo Bosco Letizia Ferroni Silvia Quartesan Alex Rizzato Marco Tatullo Barbara Zavan Hyperbaric oxygen (HBO) therapy has been reported to be beneficial for treating many conditions of inflammation-associated...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1454: Exposure to Chemotherapy During Childhood or Adulthood and Consequences on Spermatogenesis and Male Fertility International Journal of Molecular Sciences doi: 10.3390/ijms21041454 Authors: Delessard Saulnier Rives Dumont Rondanino Rives Over the last decade, the number of cancer survivors has increased thanks to progress in diagnosis and treatment. Cancer treatments are often accompanied by adverse side effects depending on the age of the...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1455: Evaluation of Transcriptomic Regulations behind Metabolic Syndrome in Obese and Lean Subjects International Journal of Molecular Sciences doi: 10.3390/ijms21041455 Authors: Magdalena Paczkowska-Abdulsalam Magdalena Niemira Agnieszka Bielska Anna Szałkowska Beata Anna Raczkowska Sini Junttila Attila Gyenesei Edyta Adamska-Patruno Katarzyna Maliszewska Anna Citko Łukasz Szczerbiński Adam Krętowski Multiple mechanisms have been...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1451: The Surprising Effect of Phenformin on Cutaneous Darkening and Characterization of Its Underlying Mechanism by a Forward Chemical Genetics Approach International Journal of Molecular Sciences doi: 10.3390/ijms21041451 Authors: Kei Takano Akira Hachiya Daiki Murase Akiko Kawasaki Hirokazu Uda Shinya Kasamatsu Yoshiya Sugai Yoshito Takahashi Tadashi Hase Atsushi Ohuchi Tamio Suzuki Melanin in the epidermis is known to ultimately...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1453: Effects of Orally Administered Resveratrol on TNF, IL-1β, Leukocyte Phagocytic Activity and Oxidative Burst Function in Horses: A Prospective, Randomized, Double-Blinded, Placebo-Controlled Study International Journal of Molecular Sciences doi: 10.3390/ijms21041453 Authors: Lynn M. Martin Philip J. Johnson Juliana R. Amorim Amy E. DeClue Resveratrol, a phytophenol, is a commonly used equine nutraceutical supplement touted to exert anti-inflammatory...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1456: Mechanisms and Therapeutic Regulation of Pyroptosis in Inflammatory Diseases and Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21041456 Authors: Zhaodi Zheng Guorong Li Programmed Cell Death (PCD) is considered to be a pathological form of cell death when mediated by an intracellular program and it balances cell death with survival of normal cells. Pyroptosis, a type of PCD, is induced by the inflammatory caspase cleavage of gasdermin...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1448: Developmental Time Course of SNAP-25 Isoforms Regulate Hippocampal Long-Term Synaptic Plasticity and Hippocampus-Dependent Learning International Journal of Molecular Sciences doi: 10.3390/ijms21041448 Authors: Katisha R. Gopaul Muhammad Irfan Omid Miry Linnea R. Vose Alexander Moghadam Galadu Subah Tomas Hökfelt Christina Bark Patric K. Stanton SNAP-25 is essential to activity-dependent vesicle fusion and neurotransmitter release in...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1450: An iTRAQ-Based Comparative Proteomics Analysis of the Biofilm and Planktonic States of Aeromonas veronii TH0426 International Journal of Molecular Sciences doi: 10.3390/ijms21041450 Authors: Ying Li Bintong Yang Jiaxin Tian Wuwen Sun Guiqin Wang Aidong Qian Chunfeng Wang Xiaofeng Shan Yuanhuan Kang Aeromonas veronii is a virulent fish pathogen that causes extensive economic losses in the aquaculture industry worldwide. In this study,...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1445: Cross-Species Root Transcriptional Network Analysis Highlights Conserved Modules in Response to Nitrate between Maize and Sorghum International Journal of Molecular Sciences doi: 10.3390/ijms21041445 Authors: Hongyang Du Lihua Ning Bing He Yuancong Wang Min Ge Jinyan Xu Han Zhao Plants have evolved complex mechanisms to respond to the fluctuation of available nitrogen (N) in soil, but the genetic mechanisms underlying the N response in crops...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1447: Influence of Diet and Nutrition on Prostate Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21041447 Authors: Makoto Matsushita Kazutoshi Fujita Norio Nonomura The incidence of prostate cancer (PCa) displays widespread regional differences, probably owing to differences in dietary habits. Nutrients, including fat, protein, carbohydrates, vitamins (vitamin A, D, and E), and polyphenols, potentially affect PCa pathogenesis and progression,...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1446: Functions of Jasmonic Acid in Plant Regulation and Response to Abiotic Stress International Journal of Molecular Sciences doi: 10.3390/ijms21041446 Authors: Jia Wang Li Song Xue Gong Jinfan Xu Minhui Li Jasmonic acid (JA) is an endogenous growth-regulating substance, initially identified as a stress-related hormone in higher plants. Similarly, the exogenous application of JA also has a regulatory effect on plants. Abiotic stress often causes large-scale...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1444: Attenuation of Hypertrophy in Human MSCs via Treatment with a Retinoic Acid Receptor Inverse Agonist International Journal of Molecular Sciences doi: 10.3390/ijms21041444 Authors: Riedl Witzmann Koch Lang Kerschbaum Baumann Krutsch Docheva Alt Pfeifer In vitro chondrogenically differentiated mesenchymal stem cells (MSCs) have a tendency to undergo hypertrophy, mirroring the fate of transient ”chondrocytes”...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1449: (+)-Limonene 1,2-Epoxide-Loaded SLNs: Evaluation of Drug Release, Antioxidant Activity, and Cytotoxicity in an HaCaT Cell Line International Journal of Molecular Sciences doi: 10.3390/ijms21041449 Authors: Eliana B. Souto Aleksandra Zielinska Selma B. Souto Alessandra Durazzo Massimo Lucarini Antonello Santini Amélia M. Silva Atanas G. Atanasov Conrado Marques Luciana N. Andrade Patricia Severino In this work, we developed a solid...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1443: Rice OsAAA-ATPase1 is Induced during Blast Infection in a Salicylic Acid-Dependent Manner, and Promotes Blast Fungus Resistance International Journal of Molecular Sciences doi: 10.3390/ijms21041443 Authors: Xinqiong Liu Haruhiko Inoue Xianying Tang Yanping Tan Xin Xu Chuntai Wang Chang-Jie Jiang Fatty acids (FAs) have been implicated in signaling roles in plant defense responses. We previously reported that mutation or RNAi-knockdown (OsSSI2-kd)...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1440: TLR3 Expression Induces Apoptosis in Human Non-Small-Cell Lung Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21041440 Authors: Bianchi Alexiadis Camisaschi Truini Centonze Milione Balsari Tagliabue Sfondrini The prognostic value of Toll-like receptor 3 (TLR3) is debated in cancer, differing between tumor types, methods, and cell types. We recently showed for the first time that TLR3 expression on early...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1442: Upregulation of Claudin-7 Expression by Angiotensin II in Colonic Epithelial Cells of Mice Fed with NaCl-Depleted Diets International Journal of Molecular Sciences doi: 10.3390/ijms21041442 Authors: Takashina Ishizuka Ikumi Hayashi Manabe Hirota Tabuchi Matsunaga Ikari Dietary NaCl depletion increases Na+ and Cl− absorption in the colon, but the mechanisms are not fully understood. So far, we reported that the expression...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1441: Characterization of Convergent Suppression by UCL-2077 (3-(Triphenylmethylaminomethyl)pyridine), Known to Inhibit Slow Afterhyperpolarization, of erg-Mediated Potassium Currents and Intermediate-Conductance Calcium-Activated Potassium Channels International Journal of Molecular Sciences doi: 10.3390/ijms21041441 Authors: Hsu Lo Wu UCL-2077 (triphenylmethylaminomethyl)pyridine) was previously reported to suppress slow afterhyperpolarization in neurons....
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1432: Persistent Breeding-Induced Endometritis in Mares - a Multifaceted Challenge: From Clinical Aspects to Immunopathogenesis and Pathobiology International Journal of Molecular Sciences doi: 10.3390/ijms21041432 Authors: Canisso Segabinazzi Fedorka Post-breeding endometritis (i.e., inflammation/infection of the endometrium), is a physiological reaction taking place in the endometrium of mares within 48 hours post-breeding, aimed to clear seminal plasma,...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1431: Transcriptome Analysis and Identification of Genes Associated with Starch Metabolism in Castanea henryi Seed (Fagaceae) International Journal of Molecular Sciences doi: 10.3390/ijms21041431 Authors: Liu Lin Jiang Jiang Xiong Lian Zeng Liu Liu Chen Starch is the most important form of carbohydrate storage and is the major energy reserve in some seeds, especially Castanea henryi. Seed germination is the beginning of the plant’s...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1437: BAK1 Mediates Light Intensity to Phosphorylate and Activate Catalases to Regulate Plant Growth and Development International Journal of Molecular Sciences doi: 10.3390/ijms21041437 Authors: Zhang Li Ren Zhao Li Wang Zhang Xiao Wang BAK1 (brassinosteroid-insensitive 1 (BRI1) associated receptor kinase 1) plays major roles in multiple signaling pathways as a coreceptor to regulate plant growth and development and stress response....
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1435: Metabolomic Analysis of Morus Cultivar Root Extracts and Their Ameliorative Effect on Testosterone-Induced Prostate Enlargement in Sprague-Dawley Rats International Journal of Molecular Sciences doi: 10.3390/ijms21041435 Authors: Choi Lee Fan Tang Yoon Ryu Kim We investigated the metabolite changes of Morus roots (MRs) according to different cultivar families (Simheung, Daesim, Cheong-il, Sangchon, Daeseong, Suhong, Suwon, and Igsu)...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1434: NADPH Oxidase Overactivity Underlies Telomere Shortening in Human Atherosclerosis International Journal of Molecular Sciences doi: 10.3390/ijms21041434 Authors: Pejenaute Cortés Marqués Montero Beloqui Fortuño Martí Orbe Zalba Telomere shortening and oxidative stress are involved in the pathogenesis of atherosclerosis. Different studies have shown that phagocytic NADPH oxidase is associated with this disease. This study aimed...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1433: Efficient Prodrug Activator Gene Therapy by Retroviral Replicating Vectors Prolongs Survival in an Immune-Competent Intracerebral Glioma Model International Journal of Molecular Sciences doi: 10.3390/ijms21041433 Authors: Chen Sun Chen Lin Chang Collins Chang Wu Lu Wang Chen Kasahara Wang Tai Prodrug activator gene therapy mediated by murine leukemia virus (MLV)-based retroviral replicating vectors (RRV)...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1436: Thyrotropin-Releasing Hormone (TRH) and Somatostatin (SST), but not Growth Hormone-Releasing Hormone (GHRH) nor Ghrelin (GHRL), Regulate Expression and Release of Immune Growth Hormone (GH) from Chicken Bursal B-Lymphocyte Cultures International Journal of Molecular Sciences doi: 10.3390/ijms21041436 Authors: Pech-Pool Berumen Martínez-Moreno García-Alcocer Carranza Luna Arámburo It is known that growth hormone (GH) is expressed in...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1438: Development of Physiologically Responsive Human iPSC-Derived Intestinal Epithelium to Study Barrier Dysfunction in IBD International Journal of Molecular Sciences doi: 10.3390/ijms21041438 Authors: John P. Gleeson Hannah Q. Estrada Michifumi Yamashita Clive N. Svendsen Stephan R. Targan Robert J. Barrett In inflammatory bowel disease (IBD), the intestinal epithelium is characterized by increased permeability both in active disease and remission...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1439: A Rare Mutation in The APOB Gene Associated with Neurological Manifestations in Familial Hypobetalipoproteinemia International Journal of Molecular Sciences doi: 10.3390/ijms21041439 Authors: Joanna Musialik Anna Boguszewska-Chachulska Dorota Pojda-Wilczek Agnieszka Gorzkowska Robert Szymańczak Magdalena Kania Agata Kujawa-Szewieczek Małgorzata Wojcieszyn Marek Hartleb Andrzej Więcek Clinical phenotypes of familial hypobetalipoproteinemia...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1430: Endocrine-Disrupting Chemicals in Human Fetal Growth International Journal of Molecular Sciences doi: 10.3390/ijms21041430 Authors: Maria Elisabeth Street Sergio Bernasconi Fetal growth is regulated by a complex interaction of maternal, placental, and fetal factors. The effects and outcomes that chemicals, widely distributed in the environment, may have on the health status of both the mother and the fetus are not yet well defined. Mainly mixtures of chemical...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1428: Calcium-Involved Action of Phytochemicals: Carotenoids and Monoterpenes in the Brain International Journal of Molecular Sciences doi: 10.3390/ijms21041428 Authors: Jowita Rzajew Tomasz Radzik Elzbieta Rebas Background: Neurodegenerative and mood disorders represent growing medical and social problems, many of which are provoked by oxidative stress, disruption in the metabolism of various neurotransmitters, and disturbances in calcium homeostasis. Biologically...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1429: Steroidogenic Factor 1 (NR5A1) Activates ATF3 Transcriptional Activity International Journal of Molecular Sciences doi: 10.3390/ijms21041429 Authors: Natsuko Emura Chiung-Min Wang William Harry Yang Wei-Hsiung Yang Steroidogenic Factor 1 (SF-1/NR5A1), an orphan nuclear receptor, is important for sexual differentiation and the development of multiple endocrine organs, as well as cell proliferation in cancer cells. Activating transcription factor 3 (ATF3)...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1427: Studies of Non-Protective Autophagy Provide Evidence that Recovery from Therapy-Induced Senescence is Independent of Early Autophagy International Journal of Molecular Sciences doi: 10.3390/ijms21041427 Authors: Saleh Tyutyunyk-Massey Patel Jr. Alotaibi Gewirtz Autophagy and senescence, predominant responses that may dictate cell fate after chemotherapy or radiation, often occur in tandem. Cells in states of senescence and/or autophagy...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1426: Multiple Skin Squamous Cell Carcinomas in Junctional Epidermolysis Bullosa Due to Altered Laminin-332 Function International Journal of Molecular Sciences doi: 10.3390/ijms21041426 Authors: Fortugno Condorelli Dellambra Guerra Cianfarani Tinaburri Proto Luca Passarelli Ricci Zambruno Castiglia Variably reduced expression of the basement membrane component laminin-332 (α3aβ3γ2) causes...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1424: Boron Toxicity and Deficiency in Agricultural Plants International Journal of Molecular Sciences doi: 10.3390/ijms21041424 Authors: Milka Brdar-Jokanović Boron is an essential plant micronutrient taken up via the roots mostly in the form of boric acid. Its important role in plant metabolism involves the stabilization of molecules with cis-diol groups. The element is involved in the cell wall and membrane structure and functioning; therefore, it participates...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1425: The Role of Calix[n]arenes and Pillar[n]arenes in the Design of Silver Nanoparticles: Self-Assembly and Application International Journal of Molecular Sciences doi: 10.3390/ijms21041425 Authors: Padnya Gorbachuk Stoikov Silver nanoparticles (AgNPs) are an attractive alternative to plasmonic gold nanoparticles. The relative cheapness and redox stability determine the growing interest of researchers in obtaining selective plasmonic and electrochemical...
Thu Feb 20, 2020 02:00
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