IJERPH, Vol. 17, Pages 1385: Dog Ownership and Walking: Perceived and Audited Walkability and Activity Correlates International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17041385 Authors: Barbara B. Brown Wyatt A. Jensen Few studies assess dog ownership and walking with both self-reported or perceived and audited or objective walkability and physical activity measures. Across two years, we examined both types of walkability and activity measures for residents...
Fri Feb 21, 2020 02:00
IJERPH, Vol. 17, Pages 1387: The Influence of Physical Activity, Diet, Weight Status and Substance Abuse on Students’ Self-Perceived Health International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17041387 Authors: José Enrique Moral-García Antonio David Agraso-López Antonio Jesús Ramos-Morcillo Alfredo Jiménez Alfredo Jiménez-Eguizábal The objective of this study was to determine the level and relationship between the self-perceived health of...
Fri Feb 21, 2020 02:00
IJERPH, Vol. 17, Pages 1383: Is Repetitive Workload a Risk Factor for Upper Extremity Musculoskeletal Disorders in Surgical Device Mechanics? A Cross-Sectional Analysis International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17041383 Authors: Oliver Lotter Tobias Lieb Viktor Breul Jochen Molsner To assess the prevalence of upper extremity work-related musculoskeletal disorders (WMSDs) among surgical device mechanics compared to a control group, a...
Fri Feb 21, 2020 02:00
IJERPH, Vol. 17, Pages 1384: Understanding Open Defecation in the Age of Swachh Bharat Abhiyan: Agency, Accountability, and Anger in Rural Bihar International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17041384 Authors: Anoop Jain Ashley Wagner Claire Snell-Rood Isha Ray Swachh Bharat Abhiyan, India’s flagship sanitation intervention, set out to end open defecation by October 2019. While the program improved toilet coverage nationally, large...
Fri Feb 21, 2020 02:00
IJERPH, Vol. 17, Pages 1382: Factors Associated with Preterm Birth and Low Birth Weight in Abu Dhabi, the United Arab Emirates International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17041382 Authors: Zainab Taha Ahmed Ali Hassan Ludmilla Wikkeling-Scott Dimitrios Papandreou Both preterm birth and low birth weight (LBW) represent major public health problems worldwide due to their association with the catastrophic effects of morbidity and mortality....
Fri Feb 21, 2020 02:00
IJMS, Vol. 21, Pages 1549: Remodeling of Intracellular Ca2+ Homeostasis in Rat Hippocampal Neurons Aged In Vitro International Journal of Molecular Sciences doi: 10.3390/ijms21041549 Authors: Calvo-Rodriguez Hernando-Pérez López-Vázquez Núñez Villalobos Núñez Aging is often associated with a cognitive decline and a susceptibility to neuronal damage. It is also the most important risk factor for neurodegenerative disorders, particularly Alzheimer’s disease...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1547: Detection of LINE-1 hypomethylation in cfDNA of Esophageal Adenocarcinoma Patients International Journal of Molecular Sciences doi: 10.3390/ijms21041547 Authors: Elisa Boldrin Matteo Curtarello Marco Dallan Rita Alfieri Stefano Realdon Matteo Fassan Daniela Saggioro DNA methylation plays an important role in cancer development. Cancer cells exhibit two types of DNA methylation alteration: site-specific hypermethylation at promoter of oncosuppressor...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1548: Combined Targeting of AKT and mTOR Inhibits Proliferation of Human NF1-Associated Malignant Peripheral Nerve Sheath Tumour Cells In Vitro but not in a Xenograft Mouse Model In Vivo International Journal of Molecular Sciences doi: 10.3390/ijms21041548 Authors: Alexander Schulte Florian Ewald Melanie Spyra Daniel J. Smit Wei Jiang Johannes Salamon Manfred Jücker Victor-Felix Mautner Persistent signalling via the PI3K/AKT/mTOR pathway is a...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1545: Analysis and Identification of Tumorigenic Targets of MicroRNA in Cancer Cells by Photoreactive Chemical Probes International Journal of Molecular Sciences doi: 10.3390/ijms21041545 Authors: Zhiyu Su Tsogzolmaa Ganbold Huricha Baigude Photoactive RNA probes have unique advantages in the identification of microRNA (miR) targets due to their ability for efficient conjugation to the target sequences by covalent crosslinking, providing stable miR-mRNA complexes...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1546: The Hypoxic Proteome and Metabolome of Barley (Hordeum vulgare L.) with and without Phytoglobin Priming International Journal of Molecular Sciences doi: 10.3390/ijms21041546 Authors: Olga A. Andrzejczak Jesper F. Havelund Wei-Qing Wang Sergey Kovalchuk Christina E. Hagensen Harald Hasler-Sheetal Ole N. Jensen Adelina Rogowska-Wrzesinska Ian Max Møller Kim H. Hebelstrup Overexpression of phytoglobins (formerly plant hemoglobins) increases...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1544: Emerging Roles of Interleukin-33-responsive Kidney Group 2 Innate Lymphoid Cells in Acute Kidney Injury International Journal of Molecular Sciences doi: 10.3390/ijms21041544 Authors: Chen Li Wu Yang Tzeng Interleukin (IL)-33, a member of the IL-1 family of cytokines, is involved in innate and adaptive immune responses. IL-33 triggers pleiotropic immune functions in multiple types of immune cells, which express the IL-33 receptor, ST2. Recent...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1543: A High Resolution Melting Analysis-Based Genotyping Toolkit for the Peach (Prunus persica) Chilling Requirement International Journal of Molecular Sciences doi: 10.3390/ijms21041543 Authors: Chou Huang Hsieh Lu Song Hsu The chilling requirement (CR) is the main factor controlling the peach floral bud break and subsequent reproductive growth. To date, several peach CR quantitative trait loci (QTLs) have been identified. To improve the accessibility...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1540: Surface Functionalization with Polyethylene Glycol and Polyethyleneimine Improves the Performance of Graphene-Based Materials for Safe and Efficient Intracellular Delivery by Laser-Induced Photoporation International Journal of Molecular Sciences doi: 10.3390/ijms21041540 Authors: Liu Li Brans Harizaj Steene De Beer De Smedt Szunerits Boukherroub Xiong Braeckmans Nanoparticle mediated laser-induced photoporation is a...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1542: Acetate and Butyrate Improve β-cell Metabolism and Mitochondrial Respiration under Oxidative Stress International Journal of Molecular Sciences doi: 10.3390/ijms21041542 Authors: Hu Kuwabara de Haan Smink de Vos Islet dysfunction mediated by oxidative and mitochondrial stress contributes to the development of type 1 and 2 diabetes. Acetate and butyrate, produced by gut microbiota via fermentation, have been shown to protect against oxidative...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1541: Emerging Potential of Exosomes in Regenerative Medicine for Temporomandibular Joint Osteoarthritis International Journal of Molecular Sciences doi: 10.3390/ijms21041541 Authors: Lee Park Auh Nah Lee Moon Heo Kim Kwon Exosomes are nanosized vesicles (30–140 nm) of endocytic origin that play important roles in regenerative medicine. They are derived from cell membranes during endocytic internalization and stabilize in...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1539: Neurons, Glia, Extracellular Matrix and Neurovascular Unit: A Systems Biology Approach to the Complexity of Synaptic Plasticity in Health and Disease International Journal of Molecular Sciences doi: 10.3390/ijms21041539 Authors: De Luca Colangelo Virtuoso Alberghina Papa The synaptic cleft has been vastly investigated in the last decades, leading to a novel and fascinating model of the functional and structural modifications linked to synaptic...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1537: Overcoming Resistance to FLT3 Inhibitors in the Treatment of FLT3-Mutated AML International Journal of Molecular Sciences doi: 10.3390/ijms21041537 Authors: Stephen S.Y. Lam Anskar Y.H. Leung Acute myeloid leukaemia (AML) carrying internal tandem duplication (ITD) of Fms-Like Tyrosine kinase 3 (FLT3) gene is associated with high risk of relapse and poor clinical outcome upon treatment with conventional chemotherapy. FLT3 inhibitors have been approved for...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1538: Synaptic GluN2A-Containing NMDA Receptors: From Physiology to Pathological Synaptic Plasticity International Journal of Molecular Sciences doi: 10.3390/ijms21041538 Authors: Franchini Carrano Di Luca Gardoni N-Methyl-d-Aspartate Receptors (NMDARs) are ionotropic glutamate-gated receptors. NMDARs are tetramers composed by several homologous subunits of GluN1-, GluN2-, or GluN3-type, leading to the existence in the central nervous system of a high...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1535: Sex and Gender Aspects for Patient Stratification in Allergy Prevention and Treatment International Journal of Molecular Sciences doi: 10.3390/ijms21041535 Authors: Massimo De Martinis Maria Maddalena Sirufo Mariano Suppa Daniela Di Silvestre Lia Ginaldi Allergies are rapidly worsening in recent decades, representing the most common immunological diseases. The mechanism of disorders such as asthma, rhinocongiuntivitis, urticaria, atopic dermatitis,...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1536: A microRNA Expression Profile as Non-Invasive Biomarker in a Large Arrhythmogenic Cardiomyopathy Cohort International Journal of Molecular Sciences doi: 10.3390/ijms21041536 Authors: Maria Bueno Marinas Rudy Celeghin Marco Cason Riccardo Bariani Anna Chiara Frigo Joanna Jager Petros Syrris Perry M. Elliott Barbara Bauce Gaetano Thiene Domenico Corrado Cristina Basso Kalliopi Pilichou Arrhythmogenic Cardiomyopathy (AC) is...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1530: An Engineered Gene Nanovehicle Developed for Smart Gene Therapy to Selectively Inhibit Smooth Muscle Cells: An In Vitro Study International Journal of Molecular Sciences doi: 10.3390/ijms21041530 Authors: Ling-Yi Cheng Yu-Chi Wang Ming-Hong Chen Fu-I Tung Kuan-Ming Chiu Tse-Ying Liu In-stent restenosis is a serious concern for patients treated through the stenting procedure, although this can be solved using drug-eluting stents and/or drug-eluting...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1534: Micronucleus Assay: The State of Art, and Future Directions International Journal of Molecular Sciences doi: 10.3390/ijms21041534 Authors: Sommer Buraczewska Kruszewski During almost 40 years of use, the micronucleus assay (MN) has become one of the most popular methods to assess genotoxicity of different chemical and physical factors, including ionizing radiation-induced DNA damage. In this minireview, we focus on the position of MN among the other...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1529: Purification of Boron Nitride Nanotubes Enhances Biological Application Properties International Journal of Molecular Sciences doi: 10.3390/ijms21041529 Authors: Soul-Hee Lee Myung Jong Kim Seokhoon Ahn Byumseok Koh Commercially available boron nitride nanotubes (BNNTs) and their purified form (pBNNTs) were dispersed in aqueous solutions with various dispersants, and their cytotoxicity and drug encapsulation capacity were monitored. Our data suggest...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1532: Endothelial Nitric Oxide Mediates the Anti-Atherosclerotic Action of Torenia concolor Lindley var. Formosama Yamazaki International Journal of Molecular Sciences doi: 10.3390/ijms21041532 Authors: Li-Ching Cheng Bei-Chia Guo Chia-Hui Chen Chi-Jen Chang Ta-Sen Yeh Tzong-Shyuan Lee Torenia concolor Lindley var. formosama Yamazaki ethanolic extract (TCEE) is reported to have anti-inflammatory and anti-obesity properties. However, the effects of...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1531: Tissue Distribution of the Readthrough Isoform of AQP4 Reveals a Dual Role of AQP4ex Limited to CNS International Journal of Molecular Sciences doi: 10.3390/ijms21041531 Authors: Palazzo Abbrescia Valente Nicchia Banitalebi Amiry-Moghaddam Trojano Frigeri Translational readthrough (TRT) of aquaporin-4 (AQP4) has remarkably expanded the importance of this new post-transcriptional mechanism, as well as the regulation potential of...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1533: Strategy of Hepatic Metabolic Defects Induced by beclin1 Heterozygosity in Adult Zebrafish International Journal of Molecular Sciences doi: 10.3390/ijms21041533 Authors: Suzan Attia Mawed Yan He Jin Zhang Jie Mei Hepatic disorders have been increasing in recent years because of high carbohydrate diets. Hepatocytes depend mainly on the basal autophagy to maintain hepatic glucose/lipid homeostasis in mammals. However, the regulatory mechanisms of autophagy...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1528: PbMYB120 Negatively Regulates Anthocyanin Accumulation in Pear International Journal of Molecular Sciences doi: 10.3390/ijms21041528 Authors: Linyan Song Xiaoli Wang Wei Han Yingying Qu Zhigang Wang Rui Zhai Chengquan Yang Fengwang Ma Lingfei Xu Subgroup 4 R2R3 MYBs play vital roles in the regulation of anthocyanin biosynthesis. However, there is limited knowledge regarding the functions of MYB repressors in pear (Pyrus × bretschneideri)....
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1527: Adaptation to Hypoxia: A Chimera? International Journal of Molecular Sciences doi: 10.3390/ijms21041527 Authors: Michele Samaja Giuseppina Milano “The Chimera was, according to Greek mythology, a monstrous fire-breathing hybrid creature of Lycia in Asia Minor, composed of the parts of more than one animal [...]
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1526: The Administration of 4-Hexylresorcinol Accelerates Orthodontic Tooth Movement and Increases the Expression Level of Bone Turnover Markers in Ovariectomized Rats International Journal of Molecular Sciences doi: 10.3390/ijms21041526 Authors: Kwang-Hyo Choi Dae-Won Kim Suk Keun Lee Seong-Gon Kim Tae-Woo Kim Surgical methods for accelerating orthodontic tooth movement are limited by possible damage to the tooth root and patient discomfort. 4-Hexylresorcinol...
Mon Feb 24, 2020 02:00
IJMS, Vol. 21, Pages 1522: Serum Levels and Removal by Haemodialysis and Haemodiafiltration of Tryptophan-Derived Uremic Toxins in ESKD Patients International Journal of Molecular Sciences doi: 10.3390/ijms21041522 Authors: Joosep Paats Annika Adoberg Jürgen Arund Annemieke Dhondt Anders Fernström Ivo Fridolin Griet Glorieux Liisi Leis Merike Luman Emilio Gonzalez-Parra Vanessa Maria Perez-Gomez Kristjan Pilt Didier Sanchez-Ospina Mårten Segelmark Fredrik...
Sun Feb 23, 2020 02:00
IJMS, Vol. 21, Pages 1524: Review of Three-Dimensional Liquid Chromatography Platforms for Bottom-Up Proteomics International Journal of Molecular Sciences doi: 10.3390/ijms21041524 Authors: Van-An Duong Jong-Moon Park Hookeun Lee Proteomics is a large-scale study of proteins, aiming at the description and characterization of all expressed proteins in biological systems. The expressed proteins are typically highly complex and large in abundance range. To fulfill high accuracy and...
Sun Feb 23, 2020 02:00
IJMS, Vol. 21, Pages 1525: Molecular Mechanisms: Connections between Nonalcoholic Fatty Liver Disease, Steatohepatitis and Hepatocellular Carcinoma International Journal of Molecular Sciences doi: 10.3390/ijms21041525 Authors: Kanda Goto Hirotsu Masuzaki Moriyama Omata Nonalcoholic fatty liver disease (NAFLD), including nonalcoholic steatohepatitis (NASH), causes hepatic fibrosis, cirrhosis and hepatocellular carcinoma (HCC). The patatin-like phospholipase-3 (PNPLA3)...
Sun Feb 23, 2020 02:00
IJMS, Vol. 21, Pages 1523: Discovery of Small-Molecule Activators for Glucose-6-Phosphate Dehydrogenase (G6PD) Using Machine Learning Approaches International Journal of Molecular Sciences doi: 10.3390/ijms21041523 Authors: Madhu Sudhana Saddala Anton Lennikov Hu Huang Glucose-6-Phosphate Dehydrogenase (G6PD) is a ubiquitous cytoplasmic enzyme converting glucose-6-phosphate into 6-phosphogluconate in the pentose phosphate pathway (PPP). The G6PD deficiency renders the inability...
Sun Feb 23, 2020 02:00
IJMS, Vol. 21, Pages 1521: Characterization of a Novel Rice Dynamic Narrow-Rolled Leaf Mutant with Deficiencies in Aromatic Amino Acids International Journal of Molecular Sciences doi: 10.3390/ijms21041521 Authors: Huimei Wang Yongfeng Shi Xiaobo Zhang Xia Xu Jian-Li Wu The leaf blade is the main photosynthetic organ and its morphology is related to light energy capture and conversion efficiency. We isolated a novel rice Dynamic Narrow-Rolled Leaf 1 (dnrl1) mutant showing...
Sun Feb 23, 2020 02:00
IJMS, Vol. 21, Pages 1520: Augmenting Vacuolar H+-ATPase Function Prevents Cardiomyocytes from Lipid-Overload Induced Dysfunction International Journal of Molecular Sciences doi: 10.3390/ijms21041520 Authors: Shujin Wang Li-Yen Wong Dietbert Neumann Yilin Liu Aomin Sun Gudrun Antoons Agnieszka Strzelecka Jan F.C. Glatz Miranda Nabben Joost J.F.P. Luiken The diabetic heart is characterized by a shift in substrate utilization from glucose to lipids, which may...
Sun Feb 23, 2020 02:00
IJMS, Vol. 21, Pages 1519: Oestrogenic Endocrine Disruptors in the Placenta and the Fetus International Journal of Molecular Sciences doi: 10.3390/ijms21041519 Authors: Zi-Run Tang Xue-Ling Xu Shou-Long Deng Zheng-Xing Lian Kun Yu Endocrine disrupting chemicals (EDCs) are exogenous substances that interfere with the stability and regulation of the endocrine system of the body or its offspring. These substances are generally stable in chemical properties, not easy to be biodegraded,...
Sun Feb 23, 2020 02:00
IJMS, Vol. 21, Pages 1518: The Molecular Mechanism of Perillaldehyde Inducing Cell Death in Aspergillus flavus by Inhibiting Energy Metabolism Revealed by Transcriptome Sequencing International Journal of Molecular Sciences doi: 10.3390/ijms21041518 Authors: Chao Pan Yong-Xin Li Kunlong Yang Erhunmwunsee Famous Yan Ma Xiaona He Qingru Geng Man Liu Jun Tian Perillaldehyde (PAE), an essential oil in Perilla plants, serves as a safe flavor ingredient in foods, and...
Sun Feb 23, 2020 02:00
IJMS, Vol. 21, Pages 1517: Mucopolysaccharidosis IVA: Diagnosis, Treatment, and Management International Journal of Molecular Sciences doi: 10.3390/ijms21041517 Authors: Kazuki Sawamoto José Víctor Álvarez González Matthew Piechnik Francisco J. Otero Maria L. Couce Yasuyuki Suzuki Shunji Tomatsu Mucopolysaccharidosis type IVA (MPS IVA, or Morquio syndrome type A) is an inherited metabolic lysosomal disease caused by the deficiency of the N-acetylglucosamine-6-sulfate...
Sun Feb 23, 2020 02:00
IJMS, Vol. 21, Pages 1501: Extranodal NK/T-Cell Lymphomas: The Role of Natural Killer Cells and EBV in Lymphomagenesis International Journal of Molecular Sciences doi: 10.3390/ijms21041501 Authors: Saleem Natkunam Keywords: NK cells, extranodal NK/T-cell lymphoma, EBV
Sat Feb 22, 2020 02:00
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