Related ArticlesParaganglioma of the Lumbar Spine: A case report and literature review. Neurochirurgie. 2019 Dec;65(6):387-392 Authors: Honeyman SI, Warr W, Curran OE, Demetriades AK Abstract INTRODUCTION: Lumbar paragangliomas are rare, vascular, neuroendocrine tumors. They are notoriously difficult to diagnose radiologically and can prove challenging to manage intraoperatively, if capable of catecholamine secretion. CASE REPORT: We report...
Thu Feb 27, 2020 13:29
Related ArticlesA mutation analysis of the EGFR pathway genes, RAS, EGFR, PIK3CA, AKT1 and BRAF, and TP53 gene in thymic carcinoma and thymoma type A/B3. Histopathology. 2019 Nov;75(5):755-766 Authors: Sakane T, Murase T, Okuda K, Saida K, Masaki A, Yamada T, Saito Y, Nakanishi R, Inagaki H Abstract AIMS: Thymic carcinoma is rare and usually has a fatal outcome. Gene mutations in the epidermal growth factor receptor (EGFR) signalling pathway and TP53...
Thu Feb 27, 2020 13:29
Related ArticlesThe role of adjuvant therapy for atypical bronchopulmonary carcinoids. Lung Cancer. 2019 05;131:90-94 Authors: Wegner RE, Abel S, Hasan S, Horne ZD, Colonias A, Weksler B, Verma V Abstract BACKGROUND: Atypical bronchopulmonary carcinoid tumors are rare but carry high recurrence rates following resection. The role of adjuvant therapy remains unclear owing to a lack of high-volume data. To address this knowledge gap, we examined predictors...
Thu Feb 27, 2020 13:29
Related ArticlesCytomegalovirus retinitis in children and adolescents with acute leukemia following allogeneic hematopoietic stem cell transplantation. Transpl Infect Dis. 2019 Oct;21(5):e13089 Authors: Zöllner SK, Herbrüggen H, Kolve H, Mihailovic N, Schubert F, Reicherts C, Rössig C, Groll AH Abstract Cytomegalovirus retinitis (CMVR) may occur after allogeneic hematopoietic stem cell transplantation (HSCT). However, little is known about its incidence,...
Thu Feb 27, 2020 13:29
Related ArticlesMultifunctional Nanosystem Based on Graphene Oxide for Synergistic Multistage Tumor-Targeting and Combined Chemo-Photothermal Therapy. Mol Pharm. 2019 05 06;16(5):1982-1998 Authors: Zhang H, Li Y, Pan Z, Chen Y, Fan Z, Tian H, Zhou S, Zhang Y, Shang J, Jiang B, Wang F, Luo F, Hou Z Abstract Locating nanomedicines at the active sites plays a pivotal role in the nanoparticle-based cancer therapy field. Herein, a multifunctional nanotherapeutic...
Thu Feb 27, 2020 13:29
Related ArticlesContrast-Enhanced Sonography in Patients with Hyposplenia: A Retrospective Analysis in Forty-Three Patients. Digestion. 2019;100(3):170-175 Authors: Trenker C, May L, Librizzi D, Neesse A, Görg C Abstract PURPOSE: In contrast to splenomegaly, the clinical value of a small spleen (hyposplenia) is unclear. Contrast-enhanced ultrasound (CEUS) has not been investigated systematically in hyposplenia. METHODS: Between February 2005...
Thu Feb 27, 2020 13:29
Related ArticlesIndirect percutaneous core needle biopsy of solid pancreatic or peripancreatic lesions. Abdom Radiol (NY). 2019 01;44(1):292-303 Authors: Chen PT, Liu KL, Cheng TY, Chang CC, Chang YC Abstract Solid pancreatic or peripancreatic lesions comprise a heterogeneous group of diseases that rely on a multimodality imaging approach for subsequent tissue procurement. Endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA)/biopsy is an...
Thu Feb 27, 2020 13:29
Related ArticlesGastrointestinal Manifestations of Hypereosinophilic Syndromes and Mast Cell Disorders: a Comprehensive Review. Clin Rev Allergy Immunol. 2019 Oct;57(2):194-212 Authors: Nanagas VC, Kovalszki A Abstract Hypereosinophilic syndrome and mastocytosis are relatively rare proliferative diseases encountered in the general population. However, allergists frequently consider these disorders in the differential of patients presenting with gastrointestinal,...
Thu Feb 27, 2020 13:29
Related ArticlesHemobilia after CT-guided radiofrequency ablation of liver tumors: frequency, risk factors, and clinical significance. Abdom Radiol (NY). 2019 01;44(1):337-345 Authors: Hsieh MF, Chen CB, Chen YL, Chou CT Abstract PURPOSE: The purpose of the study is to evaluate the frequency, risk factors, and clinical significance of hemobilia after percutaneous computed tomography (CT)-guided radiofrequency ablation (RFA) of liver tumors. ...
Thu Feb 27, 2020 13:29
Related ArticlesSlim electrodes for improved targeting in deep brain stimulation. J Neural Eng. 2020 Feb 26;: Authors: Villalobos J, McDermott HJ, McNeill P, Golod A, Rathi V, Bauquier S, Fallon JB Abstract OBJECTIVE: The efficacy of deep brain stimulation can be limited by factors including poor selectivity of stimulation, targeting error, and complications related to implant reliability and stability. We aimed to improve surgical outcomes by evaluating...
Thu Feb 27, 2020 13:26
Related ArticlesCorrelation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases. Radiology. 2020 Feb 26;:200642 Authors: Ai T, Yang Z, Hou H, Zhan C, Chen C, Lv W, Tao Q, Sun Z, Xia L Abstract Background Chest CT is used for diagnosis of 2019 novel coronavirus disease (COVID-19), as an important complement to the reverse-transcription polymerase chain reaction (RT-PCR) tests. Purpose To investigate the...
Thu Feb 27, 2020 13:24
Related ArticlesFatty Liver Disease: Artificial Intelligence Takes on the Challenge. Radiology. 2020 Feb 25;:200058 Authors: Lockhart ME, Smith AD PMID: 32101094 [PubMed - as supplied by publisher]
Thu Feb 27, 2020 13:24
Related ArticlesMyocardial Oxygenation Assessment at Myocardial Blood Oxygen Level-Dependent MRI: A Fresh Look at an Old Promise. Radiology. 2020 Feb 25;:200163 Authors: Almeida AG PMID: 32101093 [PubMed - as supplied by publisher]
Thu Feb 27, 2020 13:24
Related ArticlesIdentifying Effective Supplemental Screening Strategies for Women with a Personal History of Breast Cancer. Radiology. 2020 Feb 25;:200015 Authors: Lee CI, Lee JM PMID: 32101092 [PubMed - as supplied by publisher]
Thu Feb 27, 2020 13:24
Related ArticlesPhotoacoustic Imaging Addresses a Long-standing Challenge in Lymphedema. Radiology. 2020 Feb 25;:192824 Authors: Lillis AP, Krishnamurthy R PMID: 32101091 [PubMed - as supplied by publisher]
Thu Feb 27, 2020 13:24
Cancers, Vol. 12, Pages 551: The Clinicopathological Features and Genetic Mutations in Gastric Cancer Patients According to EMAST and MSI Status Cancers doi: 10.3390/cancers12030551 Authors: Fang Chen Huang Chang Lin Chao Lo Li Wu Shyr Background: There has been no report regarding the clinicopathological features and genetic mutations regarding elevated microsatellite alterations at selected tetranucleotide repeats (EMAST) in gastric cancer (GC)....
Thu Feb 27, 2020 02:00
Cancers, Vol. 12, Pages 552: Evaluation of the 8th Edition TNM Classification for Anaplastic Thyroid Carcinoma Cancers doi: 10.3390/cancers12030552 Authors: Onoda Sugitani Ito Suzuki Higashiyama Fukumori Suganuma Masudo Nakayama Uno Yane Yoshimoto Ebina Kawasaki Maeda Iwadate Suzuki Background: The tumor–node–metastasis (TNM) classification system to categorized anaplastic thyroid cancer (ATC) was revised....
Thu Feb 27, 2020 02:00
Cancers, Vol. 12, Pages 549: Sphere-Forming Culture for Expanding Genetically Distinct Patient-Derived Glioma Stem Cells by Cellular Growth Rate Screening Cancers doi: 10.3390/cancers12030549 Authors: Shin Shin Cho Kang Lee Seo Shin Kim Koo Kong Seol Lee Lee Nam Diffusely infiltrating gliomas (DIGs) are difficult to completely resect and are associated with a high rate of tumor relapse and progression from low- to high-grade glioma....
Thu Feb 27, 2020 02:00
Cancers, Vol. 12, Pages 547: Non-Surgical Cancer Risk Reduction in BRCA1 Mutation Carriers: Disabling the Remote Control Cancers doi: 10.3390/cancers12030547 Authors: Widschwendter Dubeau Women-specific cancers are a major health issue, particularly those associated with the BRCA1 germline mutation carrier state, which include triple-negative basal breast carcinomas and high-grade serous ovarian carcinomas (referred to as extra-uterine Müllerian carcinomas). Whereas many...
Thu Feb 27, 2020 02:00
Cancers, Vol. 12, Pages 544: Association of Cholecystectomy with the Risk of Prostate Cancer in Patients with Gallstones Cancers doi: 10.3390/cancers12030544 Authors: Chen Lin Kao Objectives: To assess the association of cholecystectomy with the risk of prostate cancer in patients with gallstones. Methods: This nationwide population-based cohort study was conducted by retrieving the Longitudinal Health Insurance Research Database (LHID2000) for inpatient claims in the Taiwan...
Thu Feb 27, 2020 02:00
Cancers, Vol. 12, Pages 546: Association of Steroids use with Survival in Patients Treated with Immune Checkpoint Inhibitors: A Systematic Review and Meta-Analysis Cancers doi: 10.3390/cancers12030546 Authors: Petrelli Signorelli Ghidini Ghidini Pizzutilo Ruggieri Cabiddu Borgonovo Dognini Brighenti De Toma Rijavec Garassino Grossi Tomasello Immune checkpoint inhibitors (ICIs) can elicit toxicities by inhibiting negative regulators...
Thu Feb 27, 2020 02:00
Cancers, Vol. 12, Pages 545: Photodynamic Therapy-Based Dendritic Cell Vaccination Suited to Treat Peritoneal Mesothelioma Cancers doi: 10.3390/cancers12030545 Authors: Trempolec Doix Degavre Brusa Bouzin Riant Feron The potential of dendritic cell (DC)-based immunotherapy to treat cancer is, nowadays, well documented. Still, the clinical success of immune checkpoint inhibitors has dampened the interest in anticancer DC vaccination. For highly life-threatening...
Thu Feb 27, 2020 02:00
Cancers, Vol. 12, Pages 548: Precision Medicine Tumor Boards: Clinical Applicability of Personalized Treatment Concepts in Ovarian Cancer Cancers doi: 10.3390/cancers12030548 Authors: Aust Schwameis Gagic Müllauer Langthaler Prager Grech Reinthaller Krainer Pils Grimm Polterauer Background: Treating cancer according to its molecular alterations (i.e., targeted treatment, TT) is the goal of precision medicine tumor boards (PTBs). Their clinical...
Thu Feb 27, 2020 02:00
Cancers, Vol. 12, Pages 550: The Effect of Cholecystectomy on the Risk of Colorectal Cancer in Patients with Gallbladder Stones Cancers doi: 10.3390/cancers12030550 Authors: Chen Lin Kao To evaluate the risk of colorectal cancer (CRC) after cholecystectomy for gallbladder stones (GBS). Methods: This nationwide population-based cohort study analyzed the inpatient data from the Taiwan National Health Insurance Research Database. The study cohort comprised of 83,963 patients aged...
Thu Feb 27, 2020 02:00
Cancers, Vol. 12, Pages 543: Autophagic Inhibition via Lysosomal Integrity Dysfunction Leads to Antitumor Activity in Glioma Treatment Cancers doi: 10.3390/cancers12030543 Authors: Hwang Cho Kim Yun Yoo Lee Kim Kwon Manipulating autophagy is a promising strategy for treating cancer as several autophagy inhibitors are shown to induce autophagic cell death. One of these, autophagonizer (APZ), induces apoptosis-independent cell death by binding an unknown target...
Thu Feb 27, 2020 02:00
Related ArticlesMapping the Steroid Response to Major Trauma From Injury to Recovery: A Prospective Cohort Study. J Clin Endocrinol Metab. 2020 Mar 01;105(3): Authors: Foster MA, Taylor AE, Hill NE, Bentley C, Bishop J, Gilligan LC, Shaheen F, Bion JF, Fallowfield JL, Woods DR, Bancos I, Midwinter MM, Lord JM, Arlt W Abstract CONTEXT: Survival rates after severe injury are improving, but complication rates and outcomes are variable. OBJECTIVE:...
Thu Feb 27, 2020 13:20
Publication date: Available online 26 February 2020Source: Revue des Maladies RespiratoiresAuthor(s):
Thu Feb 27, 2020 13:17
Related ArticlesClinical value of a set of neuropeptides in term and preterm neonates with seizures: Brain derived neurotrophic factor, galanin and neuropeptide Y. J Clin Neurosci. 2020 Feb 22;: Authors: Tanrıverdi M, Kultursay N, Tekgul H, Sozmen E, Altun Koroglu O, Aktan G, Yalaz M Abstract The aim of our study to investigate clinical value of a set of neuropeptides (brain derived neurotrophic factor-BDNF, galanin and neuropeptide Y-NPY) in critically...
Thu Feb 27, 2020 13:16
Related ArticlesVolumetric mapping of the functional neuroanatomy of the respiratory network in the perfused brainstem preparation of rats. J Physiol. 2020 Feb 25;: Authors: Dhingra RR, Dick TE, Furuya WI, Galán RF, Dutschmann M Abstract KEY POINTS: The functional neuroanatomy of the mammalian respiratory network is far from being understood since experimental tools that measure neural activity across this brainstem-wide circuit are lacking. Here, we...
Thu Feb 27, 2020 13:15
Related ArticlesUp-regulation of microRNA-30b/30d cluster represses hepatocyte apoptosis in mice with fulminant hepatic failure by inhibiting CEACAM1. IUBMB Life. 2020 Feb 26;: Authors: Zhao C, Dang Z, Sun J, Yuan S, Xie L Abstract Recently, impacts of microRNAs have been unraveled in human diseases, and we aimed to confirm the role of miR-30b/30d in fulminant hepatic failure (FHF). Expression of miR-30b/30d and CEACAM1 in serum of FHF patients and healthy...
Thu Feb 27, 2020 13:14
Related ArticlesTubulin Proteins in Cancer Resistance: A review. Curr Drug Metab. 2020 Feb 26;: Authors: Kamal MA, Al-Zahrani MH, Khan SH, Khan MH, Al Subhi HA, Kuerban A, Aslam M, Al Abassi FA, Anwar F Abstract Cancer cells are altered with cell cycle genes or they are mutated that lead to high rate of proliferation compared to normal cells. Alteration in these genes lead to mitosis dysregulation and becomes the very bases tumour progression and resistance...
Thu Feb 27, 2020 13:14
Related ArticlesAn NIR-Responsive DNA-Mediated Nanotetrahedron Enhances the Clearance of Senescent Cells. Adv Mater. 2020 Feb 25;:e2000184 Authors: Qu A, Wu X, Li S, Sun M, Xu L, Kuang H, Xu C Abstract Senescence is a state of stable cell cycle arrest that can escape apoptosis and lead to aging and numerous age-related diseases. In this study, an upconversion-nanoparticle (UCNP)-centered Au20 -Au30 nanoparticles tetrahedron (UAuTe) is prepared by DNA...
Thu Feb 27, 2020 13:14
Related ArticlesBioinformatic framework for analysis of transcription factor changes as the molecular link between replicative cellular senescence signaling pathways and carcinogenesis. Biogerontology. 2020 Feb 26;: Authors: Binenbaum I, Lefaki M, Chondrogianni N, Chatziioannou A Abstract Cellular senescence is a natural condition of irreversible cell cycle arrest and apoptotic resistance that occurs in cells exposed to various stress factors, such as...
Thu Feb 27, 2020 13:14
Related ArticlesFinding an efficient tetramethylated hydroxydiethylene of resveratrol analogue for potential anticancer agent. BMC Chem. 2020 Dec;14(1):13 Authors: Xin ZH, Meng YL, Jiang WJ, Li YP, Ge LP, Zhang CH, Liu LN, Kang YF Abstract With the improvement and advance in cancer diagnosis and treatment, the cancer is still a major cause of morbidity and mortality throughout the world. Obviously, new breakthroughs in therapies remain be urgent needed....
Thu Feb 27, 2020 13:14
Related ArticlesBioactive Compounds from Abelmoschus manihot L. Alleviate the Progression of Multiple Myeloma in Mouse Model and Improve Bone Marrow Microenvironment. Onco Targets Ther. 2020;13:959-973 Authors: Hou J, Qian J, Li Z, Gong A, Zhong S, Qiao L, Qian S, Zhang Y, Dou R, Li R, Yang Y, Gu C Abstract Purpose: Abelmoschus manihot (L.) Medik. (Malvaceae) derived Huangkui capsules (HKC) represent a traditional Chinese medicine that has been widely...
Thu Feb 27, 2020 13:14
Related ArticlesBiological and Clinical Significance of GATA3 Detected from TCGA Database and FFPE Sample in Bladder Cancer Patients. Onco Targets Ther. 2020;13:945-958 Authors: Wang C, Yang S, Jin L, Dai G, Yao Q, Xiang H, Zhang Y, Liu X, Xue B Abstract Purpose: The purpose of the present study was to investigate the biological and clinical significance of GATA binding protein 3 (GATA3) in bladder cancer patients. Patients and Methods: For...
Thu Feb 27, 2020 13:14
Related ArticlesIdentification of the Different Roles and Potential Mechanisms of T Isoforms in the Tumor Recurrence and Cell Cycle of Chordomas. Onco Targets Ther. 2019;12:11777-11791 Authors: Ma J, Chen W, Wang K, Tian K, Li Q, Zhao T, Zhang L, Wang L, Wu Z, Zhang J Abstract Purpose: The roles of T (brachyury) isoforms in chordomas remain unclear. This study aimed to investigate the different roles and mechanisms of them in chordomas. Patients...
Thu Feb 27, 2020 13:14
Related ArticlesEncapsulated n-Butylidenephthalide Efficiently Crosses the Blood-Brain Barrier and Suppresses Growth of Glioblastoma. Int J Nanomedicine. 2020;15:749-760 Authors: Lin YL, Huang XF, Chang KF, Liao KW, Tsai NM Abstract Background: n-Butylidenephthalide (BP) has anti-tumor effects on glioblastoma. However, the limitation of BP for clinical application is its unstable structure. A polycationic liposomal polyethylenimine (PEI) and polyethylene...
Thu Feb 27, 2020 13:14
Related ArticlesDistinct surfaces on Cdc5/PLK Polo-box domain orchestrate combinatorial substrate recognition during cell division. Sci Rep. 2020 Feb 25;10(1):3379 Authors: Almawi AW, Langlois-Lemay L, Boulton S, Rodríguez González J, Melacini G, D'Amours D, Guarné A Abstract Polo-like kinases (Plks) are key cell cycle regulators. They contain a kinase domain followed by a polo-box domain that recognizes phosphorylated substrates and enhances their phosphorylation....
Thu Feb 27, 2020 13:14
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