Publication date: Available online 24 February 2020Source: Medical Mycology Case ReportsAuthor(s): Najibu Kalyango, Richard Kwizera, Joseph B. Baluku, Felix Bongomin
Tue Feb 25, 2020 21:30
Publication date: Available online 24 February 2020Source: European Journal of Surgical OncologyAuthor(s): Kyoungmin Lee, Joon Seon Song, Jeong Eun Kim, Wanlim Kim, Si Yeol Song, Min Hee Lee, Hye Won Chung, Kyung-Ja Cho, Jong-Seok Lee, Jin-Hee Ahn
Tue Feb 25, 2020 21:00
Βρετανοί επιστήμονες ανακάλυψαν 24 αρκετά κοινές μεταλλάξεις γονιδίων, που συνδέονται με αυξημένο κατά δύο έως τρεις φορές κίνδυνο για καρκίνο της μήτρας (ενδομητρίου) στις γυναίκες που έχουν στο γονιδίωμα τους αυτούς τους γενετικούς παράγοντες. Οι ερευνητές των πανεπιστημίων του Μάντσεστερ και του Κέιμπριτζ, με επικεφαλής την καθηγήτρια Έμα Κρόσμπι του πρώτου, που έκαναν τη σχετική δημοσίευση στο Journal of Medical Genetics, αξιολόγησαν συστηματικά όλες τις έρευνες γονιδιώματος έως τώρα (συνολικά...
Tue Feb 25, 2020 17:12
Σε ένα κόσμο όπου τα smartphones έχουν κατακλύσει κάθε μορφή επικοινωνίας και κάθε στιγμή της καθημερινότητας ενός ανθρώπου, η ανάπτυξη εθιστικών συμπεριφορών απέναντι στις συσκευές αυτές γίνεται ολοένα και πιο απειλητική. Μπορεί κάποιοι να πιστεύουν ότι πρόκειται απλώς για ένα ψυχολογικό ζήτημα, μια νέα μελέτη, όμως, υποδεικνύει ότι αυτή η συνεχής χρήση επηρεάζει άμεσα τον εγκέφαλο και μάλιστα με τρόπο παρόμοιο με τις άλλους εθισμούς. Σύμφωνα με τη μελέτη που δημοσιεύθηκε στο Addictive Behaviors,...
Tue Feb 25, 2020 14:19
Οι ασθενείς που λαμβάνουν αντικαταθλιπτικά επί σειρά ετών καλούνται κάποια στιγμή να εξετάσουν το ενδεχόμενο διακοπής των φαρμάκων. Ωστόσο, ερευνητές αναφέρουν ότι είναι πιθανό να αντιμετωπίσουν δυσκολία ή ακόμα και επικίνδυνα συμπτώματα στέρησης λόγω της σωματικής εξάρτησης από αυτά. Σύμφωνα με τη σχετική μελέτη που δημοσιεύθηκε στο Journal of the American Osteopathic Association, η καλύτερη διαδικασία που μπορεί να ακολουθήσει κάποιος είναι ένα πρόγραμμα σταδιακής μείωσης, παράλληλα με τη συμβουλευτική...
Tue Feb 25, 2020 12:59
Οι γυναίκες άνω των 75 ετών δεν φαίνεται να έχουν κάποιο ουσιαστικό όφελος από τις τακτικές μαστογραφίες, αντίθετα με τις νεότερες γυναίκες που μπορούν να μειώσουν τον κίνδυνο θανάτου από καρκίνο του μαστού, σύμφωνα με μια νέα αμερικανική επιστημονική μελέτη. Ενώ προηγούμενες έρευνες έχουν δείξει ότι οι μαστογραφίες που ξεκινούν στα 50, μπορούν όντως να αποτρέψουν θανάτους από καρκίνο, έως τώρα ήταν ασαφές κατά πόσο αυτό ισχύει και για τις πολύ ηλικιωμένες γυναίκες, με αποτέλεσμα να αποτελεί θέμα...
Tue Feb 25, 2020 11:44
Έρευνα που πραγματοποίησαν επιστήμονες από το Πανεπιστήμιο McGill δείχνει ότι τα αγόρια που παρουσιάζουν διαταραχή ελλειμματικής προσοχής-υπερκινητικότητας (ΔΕΠΥ) στην ηλικία των 10 ετών έχουν υψηλότερο κίνδυνο τραυματικής εγκεφαλικής βλάβης (ΤΕΒ) στην εφηβεία και την ενήλικη ζωή τους και ότι οι θεραπείες για τη μείωση τέτοιων συμπεριφορών μπορεί να μειώνουν αυτόν τον κίνδυνο. «Οι τραυματικές εγκεφαλικές βλάβες αποτελούν τη μεγαλύτερη αιτία θανάτου και ανικανότητας στα παιδιά και τους νέους ενήλικες,...
Tue Feb 25, 2020 09:30
Ερευνητές από την Ιατρική Σχολή του Πανεπιστημίου της Minnesota ανακάλυψαν έναν πιθανώς νέο τρόπο με τον οποίο η διατροφή επηρεάζει τις ασθένειες που σχετίζονται με τη γήρανση, όπως αναφέρεται στη δημοσίευση της σχετικής μελέτης στο Molecular Cell. Επικεφαλής της ερευνητικής ομάδας ήταν ο καθηγητής Doug Mashek, ο οποίος μαζί με τους συνεργάτες του ανακάλυψε ότι το ελαιόλαδο, που βρίσκεται σε υψηλή θέση στη μεσογειακή διατροφή, μπορεί να αποτελεί το κλειδί για τη βελτίωση του προσδόκιμου ζωής και...
Tue Feb 25, 2020 09:00
Νέα έρευνα φαίνεται να ανακάλυψε τον τρόπο που ο χρόνος νοσηλείας για τους ασθενείς με Χρόνια Αποφρακτική Πνευμονοπάθεια (ΧΑΠ) μπορεί να μειωθεί σημαντικά, έως και 67%. Η διαδικασία που δύναται να εξασφαλίσει αυτή τη χρονική μείωση είναι εύλογη μα σπάνια συμβαίνει, όπως ισχυρίζονται οι επιστήμονες. Σύμφωνα με τα ευρήματα που δημοσιεύτηκαν στο The Journal of the American Osteopathic Association, ένα ιατρικό συμβούλιο σε καθημερινή βάση μεταξύ όλων των ειδικοτήτων που σχετίζονται με την πάθηση του...
Tue Feb 25, 2020 08:15
Abstract Background Sleep disturbances such as nonrestorative sleep and nighttime awakenings play a crucial role in fibromyalgia (FMS). Pain and sleep disturbances show a bidirectional relationship which affect outcomes in FMS. This study aims to compare sleep structures between patients with fibromyalgia and healthy controls. Methods We evaluated subjective...
Tue Feb 25, 2020 02:00
The following manuscript describes a novel method for developing a biologic, closed loop neural feedback system termed the composite regenerative peripheral nerve interface (C-RPNI). This construct has the ability to integrate with peripheral nerves to amplify efferent motor signals while simultaneously providing afferent sensory feedback.
Tue Feb 25, 2020 20:00
The use of an RNA-based approach to determine quantitative immune profiles of solid tumor tissues and leverage clinical cohorts for immune-oncology biomarker discovery is described through a molecular and informatics protocols.
Tue Feb 25, 2020 19:00
Scientists have discovered a new non-oxygen breathing animal. The tiny, less than 10-celled parasite demonstrates that evolution can go in strange directions, the researchers say.
Tue Feb 25, 2020 18:44
The purpose of this study is to present the chimeric scapula tip-free flap as a reconstructive choice in composite head and neck defects and to highlight the experiences of the authors in this field. A retrospective study and a literature review were conducted. Data about preoperative condition, intraoperative images, and radiological and clinical documentation were collected. Excision of head and neck advanced cancers may result in large composite defects containing different types of soft tissue...
Mon Feb 24, 2020 02:00
Negative-pressure pulmonary edema is a rare but life-threatening complication of septoplasty seen in the early-postoperative period. The main cause is laryngospasm; often with hypoxia and hemoptysis. In our case, a 36-year-old septoplasty recipient developed symptoms of hypotension, tachycardia and low oxygen saturation 3 hours after extubation. The patient was diagnosed with negative-pressure pulmonary edema. Treatment was applied with noninvasive positive pressure ventilation and diuretics. It...
Mon Feb 24, 2020 02:00
Nasal hump removal and modification is a commonly performed procedure in rhinoplasty. The spreader flap is most commonly used in the reconstruction technique and involves suturing the medial end of the upper lateral cartilage (ULC) onto the septum. In this study, author presents a new hump removal technique that includes a novel procedure for hump reinsertion and suturing that is easy and comfortable to apply in hump removal operations. The records of the patients were assessed retrospectively from...
Mon Feb 24, 2020 02:00
Background: Free ileocolon flap is a reliable technique allowing simultaneous restoration of swallowing and speech. The aim is to report our 6-year experience in a single center. Methods: Thirty-seven patients treated between 2010 and 2015 were included in the study. Swallowing and speech function were evaluated in 27 patients with a 7-point and 5-point Likert scale, respectively. Moreover, 12 of them consented to voice spectrum analysis (VSA). Results: Complications noted were: aspiration...
Mon Feb 24, 2020 02:00
Mon Feb 24, 2020 02:00
No abstract available
Mon Feb 24, 2020 02:00
Medial eyelid defects often damage the lacrimal drainage system, and reconstruction for these patients is challenging. The purpose of this report is to describe a new surgical technique for canalicular reconstruction using canalicular transposition. A 67-year-old female patient presented with an eyelid tumor diagnosed as a sebaceous cell carcinoma at the medial left lower eyelid. The tumor along with the lacrimal punctum and canaliculus was excised. The remnant of the canaliculus was transpositioned...
Mon Feb 24, 2020 02:00
ObjectiveNumerous exposure assessment methods (EAM) exist for investigating health effects of occupational exposure to pesticides. Direct (eg, biomonitoring) and indirect methods (eg, self-reported exposures) are however associated with degrees of exposure misclassification. We systematically reviewed EAM in studies of occupational pesticide exposure.MethodsWe searched for articles reporting observational epidemiological studies in MEDLINE and Embase published 1993 to 2017. The relative frequency...
Tue Feb 25, 2020 19:00
Species adapt to their local climates, but how often they adapt to their local communities remains a mystery. To find answers, researchers examined over 125 studies testing local adaptation in over 100 species of plants and animals.
Tue Feb 25, 2020 19:29
The discovery of a calcium channel that is likely a 'missing link' in the evolution of mammalian calcium channels has been reported today.
Tue Feb 25, 2020 17:49
Introduction. NOTCH pathway and TP53 protein are involved in the development of fibrosis and autoimmune disorders, respectively. The aim of this study was to evaluate the role of single nucleotide polymorphisms (SNPs) of NOTCH3 and TP53 genes and serum anti-TP53 antibodies with the susceptibility, clinical subset of systemic sclerosis (SSc), and clinical profile of SSc patient, particularly with lung involvement and disease activity. Objects and Methods. 124 white Polish SSc patients (101 with limited...
Tue Feb 25, 2020 16:50
TXLNA (taxilin alpha), a binding partner of the syntaxin family, was identified as a key factor in the coordination of intracellular vesicle trafficking and highly expressed in various tumor cells. However, the accurate relation between TXLNA and tumorigenesis and progression of pancreatic adenocarcinoma (PAAD) is still unclear. The present study was designed to examine the expression profile of TXLNA and explore its prognostic significance in PAAD patients and the possible molecular regulatory mechanism...
Tue Feb 25, 2020 16:35
To assess whether pulsed electromagnetic field therapy during cast immobilization of distal radius fractures has beneficial effects on pain and limb function, the study included 52 patients (mean age 60.8 ± 15.0 years) with distal radius fractures treated with cast immobilization. Patients were allocated to a pulsed electromagnetic field group (n = 27) or a control group (n = 25). Pain; forearm and arm circumference; range of motion; disabilities of the arm, shoulder, and hand score; and touch sensation...
Tue Feb 25, 2020 11:35
Background. Reducing cerebral ischemia-reperfusion injury is crucial for improving survival and neurologic outcomes after cardiac arrest/cardiopulmonary resuscitation (CA/CPR). The purpose of this study is to investigate the neuroprotective effects of green tea polyphenols (GTPs) concern with the modulation of endogenous antioxidation and endoplasmic reticulum stress. Methods. After subjecting to CA/CPR, rats were randomized into the saline group (NS, n = 40) and the GTPs group (GTPs, n = 40). Each...
Tue Feb 25, 2020 11:20
Background. Fluoxetine (FLU) is the first-line and widely used medication for depression; however, FLU treatment is almost ineffective in 30%-40% of patients with depression. In addition, there are some problems in FLU treatment, such as delayed efficacy, large side effects, and poor tolerance. Chaihu Shugan San (CSS) is a classic and effective antidepressant Chinese herbal medicine that has been used in China for thousands of years. CSS or coadministration of CSS and FLU has become one of the most...
Tue Feb 25, 2020 09:05
Objectives. To access the distinct values of contrast transcranial Doppler (cTCD), contrast transthoracic echocardiography (cTTE), and contrast transesophageal echocardiography (cTEE) in the diagnosis of right-to-left shunt (RLS) due to patent foramen ovale (PFO) and to define the most practical strategy for the diagnosis of PFO. Methods. 102 patients with a high clinical suspicion for PFO had simultaneous cTCD, cTTE, and cTEE performed. The agitated saline mixed with blood was used to detect right-to-left...
Tue Feb 25, 2020 08:50
The logistic regression (LR) model for assessing differential item functioning (DIF) is highly dependent on the asymptotic sampling distributions. However, for rare events data, the maximum likelihood estimation method may be biased and the asymptotic distributions may not be reliable. In this study, the performance of the regular maximum likelihood (ML) estimation is compared with two bias correction methods including weighted logistic regression (WLR) and Firth's penalized maximum likelihood (PML)...
Tue Feb 25, 2020 08:05
Publication date: Available online 25 February 2020Source: Clinical ImagingAuthor(s): Pranav Sharma, Rahul Hegde, Ashwini Kulkarni, Priti Soin, Puneet Kochar, Eran Rotem
Tue Feb 25, 2020 19:43
Publication date: Available online 25 February 2020Source: Clinical ImagingAuthor(s): Licia Pacheco Luna, Isabelle Meneses da Ponte, Isabella Bezerra Oliveira, Francisco Ramos, Gunter Gerson
Tue Feb 25, 2020 19:43
The silkworm Bombyx mori (B. mori) is an important domesticated lepidopteran model for basic and applied research. They produce silk fibres that have great economic value. The gut microbiome plays an important ro...
Mon Feb 24, 2020 02:00
Although controversial, there is increasing concern that Crohn’s disease may be a zoonotic infectious disease consequent to a mycobacterial infection. The most plausible candidate is M. avium subspecies paratuber...
Mon Feb 24, 2020 02:00
Molecular typing methods are useful for rapid detection and control of a disease. Recently, the use of high-resolution melting (HRM) for spa typing of MRSA isolates were reported. This technique is rapid, inexpen...
Mon Feb 24, 2020 02:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου