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Τετάρτη 26 Φεβρουαρίου 2020


Intra-cavitary pulmonary cryptococcoma in poorly controlled diabetes mellitus
Publication date: Available online 24 February 2020Source: Medical Mycology Case ReportsAuthor(s): Najibu Kalyango, Richard Kwizera, Joseph B. Baluku, Felix Bongomin
Medical Mycology Case Reports
Tue Feb 25, 2020 21:30
The clinical outcomes of undifferentiated pleomorphic sarcoma (UPS): a single-centre experience of two decades with the assessment of PD-L1 expressions
Publication date: Available online 24 February 2020Source: European Journal of Surgical OncologyAuthor(s): Kyoungmin Lee, Joon Seon Song, Jeong Eun Kim, Wanlim Kim, Si Yeol Song, Min Hee Lee, Hye Won Chung, Kyung-Ja Cho, Jong-Seok Lee, Jin-Hee Ahn
European Journal of Surgical Oncology (EJSO)
Tue Feb 25, 2020 21:00
Καρκίνος ενδομητρίου: Ποιες γυναίκες διατρέχουν τριπλάσιο κίνδυνο νόσου
Βρετανοί επιστήμονες ανακάλυψαν 24 αρκετά κοινές μεταλλάξεις γονιδίων, που συνδέονται με αυξημένο κατά δύο έως τρεις φορές κίνδυνο για καρκίνο της μήτρας (ενδομητρίου) στις γυναίκες που έχουν στο γονιδίωμα τους αυτούς τους γενετικούς παράγοντες. Οι ερευνητές των πανεπιστημίων του Μάντσεστερ και του Κέιμπριτζ, με επικεφαλής την καθηγήτρια Έμα Κρόσμπι του πρώτου, που έκαναν τη σχετική δημοσίευση στο Journal of Medical Genetics, αξιολόγησαν συστηματικά όλες τις έρευνες γονιδιώματος έως τώρα (συνολικά...
Επιστημονικές Εξελίξεις – ygeiamou | Το αξιόπιστο site για την Υγεία, τη Διατροφή και την Ευεξία
Tue Feb 25, 2020 17:12
Η εθιστική συνήθεια που φέρνει τα πάνω κάτω στον εγκέφαλο
Σε ένα κόσμο όπου τα smartphones έχουν κατακλύσει κάθε μορφή επικοινωνίας και κάθε στιγμή της καθημερινότητας ενός ανθρώπου, η ανάπτυξη εθιστικών συμπεριφορών απέναντι στις συσκευές αυτές γίνεται ολοένα και πιο απειλητική. Μπορεί κάποιοι να πιστεύουν ότι πρόκειται απλώς για ένα ψυχολογικό ζήτημα, μια νέα μελέτη, όμως, υποδεικνύει ότι αυτή η συνεχής χρήση επηρεάζει άμεσα τον εγκέφαλο και μάλιστα με τρόπο παρόμοιο με τις άλλους εθισμούς. Σύμφωνα με τη μελέτη που δημοσιεύθηκε στο Addictive Behaviors,...
Επιστημονικές Εξελίξεις – ygeiamou | Το αξιόπιστο site για την Υγεία, τη Διατροφή και την Ευεξία
Tue Feb 25, 2020 14:19
Γιατί δεν κόβονται «μαχαίρι» τα αντικαταθλιπτικά
Οι ασθενείς που λαμβάνουν αντικαταθλιπτικά επί σειρά ετών καλούνται κάποια στιγμή να εξετάσουν το ενδεχόμενο διακοπής των φαρμάκων. Ωστόσο, ερευνητές αναφέρουν ότι είναι πιθανό να αντιμετωπίσουν δυσκολία ή ακόμα και επικίνδυνα συμπτώματα στέρησης λόγω της σωματικής εξάρτησης από αυτά. Σύμφωνα με τη σχετική μελέτη που δημοσιεύθηκε στο Journal of the American Osteopathic Association, η καλύτερη διαδικασία που μπορεί να ακολουθήσει κάποιος είναι ένα πρόγραμμα σταδιακής μείωσης, παράλληλα με τη συμβουλευτική...
Επιστημονικές Εξελίξεις – ygeiamou | Το αξιόπιστο site για την Υγεία, τη Διατροφή και την Ευεξία
Tue Feb 25, 2020 12:59
Μαστογραφία: Σε ποιες γυναίκες δεν παρέχουν όφελος
Οι γυναίκες άνω των 75 ετών δεν φαίνεται να έχουν κάποιο ουσιαστικό όφελος από τις τακτικές μαστογραφίες, αντίθετα με τις νεότερες γυναίκες που μπορούν να μειώσουν τον κίνδυνο θανάτου από καρκίνο του μαστού, σύμφωνα με μια νέα αμερικανική επιστημονική μελέτη. Ενώ προηγούμενες έρευνες έχουν δείξει ότι οι μαστογραφίες που ξεκινούν στα 50, μπορούν όντως να αποτρέψουν θανάτους από καρκίνο, έως τώρα ήταν ασαφές κατά πόσο αυτό ισχύει και για τις πολύ ηλικιωμένες γυναίκες, με αποτέλεσμα να αποτελεί θέμα...
Επιστημονικές Εξελίξεις – ygeiamou | Το αξιόπιστο site για την Υγεία, τη Διατροφή και την Ευεξία
Tue Feb 25, 2020 11:44
Ο κίνδυνος που απειλεί τα παιδιά με υπερκινητικότητα
Έρευνα που πραγματοποίησαν επιστήμονες από το Πανεπιστήμιο McGill δείχνει ότι τα αγόρια που παρουσιάζουν διαταραχή ελλειμματικής προσοχής-υπερκινητικότητας (ΔΕΠΥ) στην ηλικία των 10 ετών έχουν υψηλότερο κίνδυνο τραυματικής εγκεφαλικής βλάβης (ΤΕΒ) στην εφηβεία και την ενήλικη ζωή τους και ότι οι θεραπείες για τη μείωση τέτοιων συμπεριφορών μπορεί να μειώνουν αυτόν τον κίνδυνο. «Οι τραυματικές εγκεφαλικές βλάβες αποτελούν τη μεγαλύτερη αιτία θανάτου και ανικανότητας στα παιδιά και τους νέους ενήλικες,...
Επιστημονικές Εξελίξεις – ygeiamou | Το αξιόπιστο site για την Υγεία, τη Διατροφή και την Ευεξία
Tue Feb 25, 2020 09:30
Το μεσογειακό υπερτρόφιμο που νικά τη γήρανση
Ερευνητές από την Ιατρική Σχολή του Πανεπιστημίου της Minnesota ανακάλυψαν έναν πιθανώς νέο τρόπο με τον οποίο η διατροφή επηρεάζει τις ασθένειες που σχετίζονται με τη γήρανση, όπως αναφέρεται στη δημοσίευση της σχετικής μελέτης στο Molecular Cell. Επικεφαλής της ερευνητικής ομάδας ήταν ο καθηγητής Doug Mashek, ο οποίος μαζί με τους συνεργάτες του ανακάλυψε ότι το ελαιόλαδο, που βρίσκεται σε υψηλή θέση στη μεσογειακή διατροφή, μπορεί να αποτελεί το κλειδί για τη βελτίωση του προσδόκιμου ζωής και...
Επιστημονικές Εξελίξεις – ygeiamou | Το αξιόπιστο site για την Υγεία, τη Διατροφή και την Ευεξία
Tue Feb 25, 2020 09:00
ΧΑΠ: Αυτοί οι ασθενείς μένουν λιγότερο στο νοσοκομείο
Νέα έρευνα φαίνεται να ανακάλυψε τον τρόπο που ο χρόνος νοσηλείας για τους ασθενείς με Χρόνια Αποφρακτική Πνευμονοπάθεια (ΧΑΠ) μπορεί να μειωθεί σημαντικά, έως και 67%. Η διαδικασία που δύναται να εξασφαλίσει αυτή τη χρονική μείωση είναι εύλογη μα σπάνια συμβαίνει, όπως ισχυρίζονται οι επιστήμονες. Σύμφωνα με τα ευρήματα που δημοσιεύτηκαν στο The Journal of the American Osteopathic Association, ένα ιατρικό συμβούλιο σε καθημερινή βάση μεταξύ όλων των ειδικοτήτων που σχετίζονται με την πάθηση του...
Επιστημονικές Εξελίξεις – ygeiamou | Το αξιόπιστο site για την Υγεία, τη Διατροφή και την Ευεξία
Tue Feb 25, 2020 08:15
Comparison of sleep structure in patients with fibromyalgia and healthy controls
Abstract Background Sleep disturbances such as nonrestorative sleep and nighttime awakenings play a crucial role in fibromyalgia (FMS). Pain and sleep disturbances show a bidirectional relationship which affect outcomes in FMS. This study aims to compare sleep structures between patients with fibromyalgia and healthy controls. Methods We evaluated subjective...
Latest Results for Sleep and Breathing
Tue Feb 25, 2020 02:00
Fetal subependymal giant cell astrocytoma: A case report and review of the literature
Fetal subependymal giant cell astrocytoma: A case report and review of the literature Category: Article Type: Aikaterini Karagianni, Ploutarchos Karydakis, Dimitrios Giakoumettis, Ioannis Nikas, George Sfakianos, Marios ThemistocleousDepartment of Neurosurgery, “K.A.T.-N.R.C.” General Hospital of Attica,Department of Neurosurgery, 251 Hellenic Air Force General Hospital,Department of Neurosurgery,...
Surgical neurology international
Tue Feb 25, 2020 19:42
The relationship between preoperative predictive factors for clinical outcome in patients operated for lumbar spinal stenosis by decompressive laminectomy
The relationship between preoperative predictive factors for clinical outcome in patients operated for lumbar spinal stenosis by decompressive laminectomy Category: Article Type: Dobran Mauro, Davide Nasi, Riccardo Paracino, Mara Capece, Erika Carrassi, Denis Aiudi, Fabrizio Mancini, Simona Lattanzi, Roberto Colasanti, Maurizio Iacoangeli Departments of Neurosurgery, Università Politecnica delle...
Surgical neurology international
Tue Feb 25, 2020 19:41
Stenotrophomonas maltophilia spondylodiscitis following lumbar microdiscectomy mimicking a cotton granuloma: A case report and literature review
Stenotrophomonas maltophilia spondylodiscitis following lumbar microdiscectomy mimicking a cotton granuloma: A case report and literature review Category: Article Type: Nitin Maruti Adsul, Vishnu Panigrahi, Shankar Acharya, K. L. Kalra, R. S. ChahalDepartment of Ortho-Spine Surgery, Sir Ganga Ram Hospital, New Delhi, Delhi, India.DOI:10.25259/SNI_23_2020Copyright: © 2020 Surgical Neurology International...
Surgical neurology international
Tue Feb 25, 2020 19:40
Fabrication of the Composite Regenerative Peripheral Nerve Interface (C-RPNI) in the Adult Rat
The following manuscript describes a novel method for developing a biologic, closed loop neural feedback system termed the composite regenerative peripheral nerve interface (C-RPNI). This construct has the ability to integrate with peripheral nerves to amplify efferent motor signals while simultaneously providing afferent sensory feedback.
JoVE: Journal of Visualized Experiments
Tue Feb 25, 2020 20:00
Predictive Immune Modeling of Solid Tumors
The use of an RNA-based approach to determine quantitative immune profiles of solid tumor tissues and leverage clinical cohorts for immune-oncology biomarker discovery is described through a molecular and informatics protocols.
JoVE: Journal of Visualized Experiments
Tue Feb 25, 2020 19:00
Unique non-oxygen breathing animal discovered
Scientists have discovered a new non-oxygen breathing animal. The tiny, less than 10-celled parasite demonstrates that evolution can go in strange directions, the researchers say.
Evolutionary Biology News -- ScienceDaily
Tue Feb 25, 2020 18:44
Reconstruction of Complex Oromandibular Defects in Head and Neck Cancer: Role of the Chimeric Subscapular Free Flap
The purpose of this study is to present the chimeric scapula tip-free flap as a reconstructive choice in composite head and neck defects and to highlight the experiences of the authors in this field. A retrospective study and a literature review were conducted. Data about preoperative condition, intraoperative images, and radiological and clinical documentation were collected. Excision of head and neck advanced cancers may result in large composite defects containing different types of soft tissue...
Journal of Craniofacial Surgery - Published Ahead-of-Print
Mon Feb 24, 2020 02:00
Negative-Pressure Pulmonary Edema After Septoplasty
Negative-pressure pulmonary edema is a rare but life-threatening complication of septoplasty seen in the early-postoperative period. The main cause is laryngospasm; often with hypoxia and hemoptysis. In our case, a 36-year-old septoplasty recipient developed symptoms of hypotension, tachycardia and low oxygen saturation 3 hours after extubation. The patient was diagnosed with negative-pressure pulmonary edema. Treatment was applied with noninvasive positive pressure ventilation and diuretics. It...
Journal of Craniofacial Surgery - Published Ahead-of-Print
Mon Feb 24, 2020 02:00
A Novel Hump Reinsertion Technique to Reconstruct the Nasal Dorsum
Nasal hump removal and modification is a commonly performed procedure in rhinoplasty. The spreader flap is most commonly used in the reconstruction technique and involves suturing the medial end of the upper lateral cartilage (ULC) onto the septum. In this study, author presents a new hump removal technique that includes a novel procedure for hump reinsertion and suturing that is easy and comfortable to apply in hump removal operations. The records of the patients were assessed retrospectively from...
Journal of Craniofacial Surgery - Published Ahead-of-Print
Mon Feb 24, 2020 02:00
Simultaneous Restoration of Swallowing and Voice Function With Ileocolon Free Flap
Background: Free ileocolon flap is a reliable technique allowing simultaneous restoration of swallowing and speech. The aim is to report our 6-year experience in a single center. Methods: Thirty-seven patients treated between 2010 and 2015 were included in the study. Swallowing and speech function were evaluated in 27 patients with a 7-point and 5-point Likert scale, respectively. Moreover, 12 of them consented to voice spectrum analysis (VSA). Results: Complications noted were: aspiration...
Journal of Craniofacial Surgery - Published Ahead-of-Print
Mon Feb 24, 2020 02:00
Review of “Association of Overlapping, Nonconcurrent, Surgery With Patient Outcomes at a Large Academic Medical Center: A Coarsened Exact Matching Study” by Glauser G et al in: Ann Surg: 270:620-629, 2019
No abstract available
Journal of Craniofacial Surgery - Published Ahead-of-Print
Mon Feb 24, 2020 02:00
Delivery of Health Care to the Craniofacially Deformed: A Long Term Global View
No abstract available
Journal of Craniofacial Surgery - Published Ahead-of-Print
Mon Feb 24, 2020 02:00
Lacrimal Canalicular Reconstruction With Canalicular Transposition
Medial eyelid defects often damage the lacrimal drainage system, and reconstruction for these patients is challenging. The purpose of this report is to describe a new surgical technique for canalicular reconstruction using canalicular transposition. A 67-year-old female patient presented with an eyelid tumor diagnosed as a sebaceous cell carcinoma at the medial left lower eyelid. The tumor along with the lacrimal punctum and canaliculus was excised. The remnant of the canaliculus was transpositioned...
Journal of Craniofacial Surgery - Published Ahead-of-Print
Mon Feb 24, 2020 02:00
Systematic review of methods used to assess exposure to pesticides in occupational epidemiology studies, 1993-2017
ObjectiveNumerous exposure assessment methods (EAM) exist for investigating health effects of occupational exposure to pesticides. Direct (eg, biomonitoring) and indirect methods (eg, self-reported exposures) are however associated with degrees of exposure misclassification. We systematically reviewed EAM in studies of occupational pesticide exposure.MethodsWe searched for articles reporting observational epidemiological studies in MEDLINE and Embase published 1993 to 2017. The relative frequency...
OEM Online First
Tue Feb 25, 2020 19:00
Adaptation: Competition and predation may not be the driving force scientists thought
Species adapt to their local climates, but how often they adapt to their local communities remains a mystery. To find answers, researchers examined over 125 studies testing local adaptation in over 100 species of plants and animals.
Evolutionary Biology News -- ScienceDaily
Tue Feb 25, 2020 19:29
Discovery of bacterial ancestor yields new insight on calcium channels
The discovery of a calcium channel that is likely a 'missing link' in the evolution of mammalian calcium channels has been reported today.
Evolutionary Biology News -- ScienceDaily
Tue Feb 25, 2020 17:49
NOTCH3 T6746C and TP53 P72R Polymorphisms Are Associated with the Susceptibility to Diffuse Cutaneous Systemic Sclerosis
Introduction. NOTCH pathway and TP53 protein are involved in the development of fibrosis and autoimmune disorders, respectively. The aim of this study was to evaluate the role of single nucleotide polymorphisms (SNPs) of NOTCH3 and TP53 genes and serum anti-TP53 antibodies with the susceptibility, clinical subset of systemic sclerosis (SSc), and clinical profile of SSc patient, particularly with lung involvement and disease activity. Objects and Methods. 124 white Polish SSc patients (101 with limited...
BioMed Research International
Tue Feb 25, 2020 16:50
High TXLNA Expression Predicts Favourable Outcome for Pancreatic Adenocarcinoma Patients
TXLNA (taxilin alpha), a binding partner of the syntaxin family, was identified as a key factor in the coordination of intracellular vesicle trafficking and highly expressed in various tumor cells. However, the accurate relation between TXLNA and tumorigenesis and progression of pancreatic adenocarcinoma (PAAD) is still unclear. The present study was designed to examine the expression profile of TXLNA and explore its prognostic significance in PAAD patients and the possible molecular regulatory mechanism...
BioMed Research International
Tue Feb 25, 2020 16:35
Beneficial Effects of Pulsed Electromagnetic Field during Cast Immobilization in Patients with Distal Radius Fracture
To assess whether pulsed electromagnetic field therapy during cast immobilization of distal radius fractures has beneficial effects on pain and limb function, the study included 52 patients (mean age 60.8 ± 15.0 years) with distal radius fractures treated with cast immobilization. Patients were allocated to a pulsed electromagnetic field group (n = 27) or a control group (n = 25). Pain; forearm and arm circumference; range of motion; disabilities of the arm, shoulder, and hand score; and touch sensation...
BioMed Research International
Tue Feb 25, 2020 11:35
Green Tea Polyphenols Modulated Cerebral SOD Expression and Endoplasmic Reticulum Stress in Cardiac Arrest/Cardiopulmonary Resuscitation Rats
Background. Reducing cerebral ischemia-reperfusion injury is crucial for improving survival and neurologic outcomes after cardiac arrest/cardiopulmonary resuscitation (CA/CPR). The purpose of this study is to investigate the neuroprotective effects of green tea polyphenols (GTPs) concern with the modulation of endogenous antioxidation and endoplasmic reticulum stress. Methods. After subjecting to CA/CPR, rats were randomized into the saline group (NS, n = 40) and the GTPs group (GTPs, n = 40). Each...
BioMed Research International
Tue Feb 25, 2020 11:20
Antidepressant-Like Effects and Cognitive Enhancement of Coadministration of Chaihu Shugan San and Fluoxetine: Dependent on the BDNF-ERK-CREB Signaling Pathway in the Hippocampus and Frontal Cortex
Background. Fluoxetine (FLU) is the first-line and widely used medication for depression; however, FLU treatment is almost ineffective in 30%-40% of patients with depression. In addition, there are some problems in FLU treatment, such as delayed efficacy, large side effects, and poor tolerance. Chaihu Shugan San (CSS) is a classic and effective antidepressant Chinese herbal medicine that has been used in China for thousands of years. CSS or coadministration of CSS and FLU has become one of the most...
BioMed Research International
Tue Feb 25, 2020 09:05
Diagnosis of Patent Foramen Ovale: The Combination of Contrast Transcranial Doppler, Contrast Transthoracic Echocardiography, and Contrast Transesophageal Echocardiography
Objectives. To access the distinct values of contrast transcranial Doppler (cTCD), contrast transthoracic echocardiography (cTTE), and contrast transesophageal echocardiography (cTEE) in the diagnosis of right-to-left shunt (RLS) due to patent foramen ovale (PFO) and to define the most practical strategy for the diagnosis of PFO. Methods. 102 patients with a high clinical suspicion for PFO had simultaneous cTCD, cTTE, and cTEE performed. The agitated saline mixed with blood was used to detect right-to-left...
BioMed Research International
Tue Feb 25, 2020 08:50
A Comparative Study of the Bias Correction Methods for Differential Item Functioning Analysis in Logistic Regression with Rare Events Data
The logistic regression (LR) model for assessing differential item functioning (DIF) is highly dependent on the asymptotic sampling distributions. However, for rare events data, the maximum likelihood estimation method may be biased and the asymptotic distributions may not be reliable. In this study, the performance of the regular maximum likelihood (ML) estimation is compared with two bias correction methods including weighted logistic regression (WLR) and Firth's penalized maximum likelihood (PML)...
BioMed Research International
Tue Feb 25, 2020 08:05
Imaging right lower quadrant pain: Not always appendicitis
Publication date: Available online 25 February 2020Source: Clinical ImagingAuthor(s): Pranav Sharma, Rahul Hegde, Ashwini Kulkarni, Priti Soin, Puneet Kochar, Eran Rotem
Clinical Imaging
Tue Feb 25, 2020 19:43
Pleomorphic xanthoastrocytoma in the posterior fossa: a case report with advanced neuroimaging findings
Publication date: Available online 25 February 2020Source: Clinical ImagingAuthor(s): Licia Pacheco Luna, Isabelle Meneses da Ponte, Isabella Bezerra Oliveira, Francisco Ramos, Gunter Gerson
Clinical Imaging
Tue Feb 25, 2020 19:43
16S rRNA sequence data of Bombyx mori gut bacteriome after spermidine supplementation
The silkworm Bombyx mori (B. mori) is an important domesticated lepidopteran model for basic and applied research. They produce silk fibres that have great economic value. The gut microbiome plays an important ro...
BMC Research Notes
Mon Feb 24, 2020 02:00
Crohn’s disease: failure of a proprietary fluorescent in situ hybridization assay to detect M. avium subspecies paratuberculosis in archived frozen intestine from patients with Crohn’s disease.
Although controversial, there is increasing concern that Crohn’s disease may be a zoonotic infectious disease consequent to a mycobacterial infection. The most plausible candidate is M. avium subspecies paratuber...
BMC Research Notes
Mon Feb 24, 2020 02:00
Determining spa-type of methicillin-resistant Staphylococcus aureus (MRSA) via high-resolution melting (HRM) analysis, Shiraz, Iran
Molecular typing methods are useful for rapid detection and control of a disease. Recently, the use of high-resolution melting (HRM) for spa typing of MRSA isolates were reported. This technique is rapid, inexpen...
BMC Research Notes
Mon Feb 24, 2020 02:00

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