New England Journal of Medicine, Ahead of Print.
Wed Feb 26, 2020 12:00
New England Journal of Medicine, Volume 382, Issue 9, Page 874-875, February 2020.
Wed Feb 26, 2020 12:00
New England Journal of Medicine, Volume 382, Issue 9, February 2020.
Wed Feb 26, 2020 12:00
New England Journal of Medicine, Ahead of Print.
Wed Feb 26, 2020 12:00
New England Journal of Medicine, Ahead of Print.
Wed Feb 26, 2020 12:00
Publication date: Available online 26 February 2020Source: NeuroImageAuthor(s): Wojciech Pietrasik, Ivor Cribben, Fraser Olsen, Yushan Huang, Nikolai V. Malykhin
Thu Feb 27, 2020 11:57
Publication date: Available online 26 February 2020Source: NeuroImageAuthor(s): Nicholas Furl, Forida Begum, Justin Sulik, Francesca Pizzorni Ferrarese, Sarah Jans, Caroline Woolley
Thu Feb 27, 2020 11:57
Publication date: Available online 26 February 2020Source: NeuroImageAuthor(s): David T. Field, Nicolo Biagi, Laura A. Inman
Thu Feb 27, 2020 11:57
Acute spinal cord infarct in childhood is extremely rare, generally secondary to spinal/cardiovascular surgery or severe vertebral injuries. However, spontaneous spinal cord infarct cases have been described. We present a clinical case of a teenager who developed an acute weakness and paraesthesia in lower limbs after playing piggyback. Laboratory tests and MRI (magnetic resonance imaging) were normal. During her hospital admission, her motor strength improved. After 10 days, MRI was repeated, and...
Thu Feb 27, 2020 06:05
Presentation of Case. Dr. Douglas S. Micalizzi (Medicine): A 52-year-old man was referred to the multidisciplinary breast clinic of this hospital for evaluation and management of invasive ductal carcinoma of the left breast. Seven weeks before the current evaluation, the patient felt a nontender…
Thu Feb 27, 2020 02:00
To become the first-line treatment for patients with aortic stenosis, transcatheter aortic-valve replacement (TAVR) must not only mitigate periprocedural events but also be as effective as surgical aortic-valve replacement in the long term. Makkar et al. examined this question and report in this…
Thu Feb 27, 2020 02:00
AbstractLeiomyosarcomas are rare, primary malignancies that can be found in the small bowel in a minority of cases. The management of these visceral sarcomas remains controversial, with surgical resection forming the mainstay, being optimally achieved in a unit familiar with the management of sarcomas. These tumours are difficult to diagnose based on history and are challenging to localize on conventional imaging modalities. We report a case of a 61-year-old female who proceeded to emergent laparotomy...
Thu Feb 27, 2020 02:00
Abstract Objectives Human language represents an extreme form of communicative complexity. Primate facial display complexity, which depends upon facial mobility, can be used as a model for the study of the evolution of communicative complexity. The gelada (Theropithecus gelada) is the only primate that can produce a lip‐flip eversion. This study investigates the role of the lip‐flip relative to the bared‐teeth display to understand its role in generating communicative complexity. Materials...
Thu Feb 27, 2020 11:27
Abstract Intraductal papillary neoplasm of the bile duct (IPNB) is a grossly visible papillary biliary neoplasm with morphological variations and occasional invasion. Recently, a new classification of IPNB into type 1 and type 2 was proposed in which the type 1 IPNBs consist of fine papillary neoplastic glands whereas the type 2 IPNBs consist of complex branching glands seldom with foci of solid‐tubular components. However, clinicopathological and molecular characteristics of these types of IPNBs...
Thu Feb 27, 2020 10:47
Abstract Our genomes contain the blueprint of what makes us human and many indications as to why we develop disease. Until the last ten years, most studies had focussed on protein‐coding genes, more specifically DNA sequences coding for proteins. However, this represents less than 5% of our genomes. The other 95% is referred to as the ‘dark matter’ of our genomes, our understanding of which is extremely limited. Part of this ‘dark matter’ includes regions that give rise to RNAs that do not code...
Thu Feb 27, 2020 10:47
Background Despite the well‐defined role of minimal residual disease (MRD) monitoring by real‐time quantitative polymerase chain reaction (RT‐PCR) for RUNX1/RUNX1T1 and CBFB‐MYH11 transcripts in core binding factor (CBF) acute myeloid leukemia (AML) after intensive chemotherapy, there has been a paucity of data assessing the utility of MRD monitoring at and after allogeneic hematopoietic stem cell transplantation (HSCT). Methods Patients with CBF AML who underwent HSCT in complete remission...
Thu Feb 27, 2020 10:45
Background To the authors' knowledge, there are limited data regarding the epidemiology of malignant appendiceal tumors. It remains unknown whether the previously reported trends are occurring in different countries and/or continuing in recent years and/or whether they are possibly due to increasing rates of appendectomies. In the current study, the authors investigated the patterns and time trends of malignant appendiceal tumor diagnosis by age group, sex, stage of disease, and histology in Canada...
Thu Feb 27, 2020 10:45
Purpose of review The vessel-depleted neck is the ultimate challenge for the head and neck reconstructive surgeon. In patients who have had previous neck dissections or radiotherapy, the arterial and venous options for future reconstruction can be very limited, and it is important for the surgeon to consider alternative options for vessels. Recent findings Appropriate preoperative planning is crucial in these patients with a thorough history including previous operation notes, details of...
Tue Feb 25, 2020 02:00
Purpose of review Electrochemotherapy (ECT) is increasingly used in different settings in head and neck cancer patients when conventional treatment options are not available. Recent findings Recent improvements of electroporation and ECT include new advanced electrode probes, the combination with intratumorally injected supraphysiological doses of calcium and an update of the standard operating procedures. Summary ECT is a treatment modality that combines administration of a chemotherapeutic...
Tue Feb 25, 2020 02:00
Purpose of review Chordomas of the clival region are challenging tumors to treat due to their location and infiltrative behavior. The primary goal of treatment remains a gross total resection (GTR). Advances in surgical techniques, especially the adoption of endoscopic endonasal techniques, provide improved rates of surgical resection while minimizing secondary surgical morbidities. Recent findings Advances in the management of clival chordomas include further development of endoscopic endonasal...
Tue Feb 25, 2020 02:00
Purpose of review The progressive growth of endoscopic and robotic-assisted procedures provided the tools for development of remote approaches to the neck, which could avoid a visible large neck scar usually necessary for neck dissections. This review explores the current experience with robotic neck dissection, looking for pros and cons in surgical, oncologic and aesthetic outcomes. Recent findings Robotic neck dissection was shown to be feasible and well tolerated, with adequate oncological...
Tue Feb 25, 2020 02:00
Purpose of review The present review describes the latest development of 3D virtual surgical planning (VSP) and computer aided design (CAD) for reconstruction of maxillary defects with an aim of fully prosthetic rehabilitation. The purpose is to give an overview of different methods that use CAD in maxillary reconstruction in patients with head and neck cancer. Recent findings 3D VSP enables preoperative planning of resection margins and osteotomies. The current 3D VSP workflow is expanded...
Tue Feb 25, 2020 02:00
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