IJERPH, Vol. 17, Pages 1468: Environmental Impact of Dietary Choices: Role of the Mediterranean and Other Dietary Patterns in an Italian Cohort International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17051468 Authors: Grosso Fresán Bes-Rastrollo Marventano Galvano Background: Current scientific literature suggests healthy dietary patterns may have less environmental impact than current consumption patterns, but most of the studies rely on...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1579: Anti-Inflammatory and Anti-Oxidative Activity of Indole-3-Acetic Acid Involves Induction of HO-1 and Neutralization of Free Radicals in RAW264.7 Cells International Journal of Molecular Sciences doi: 10.3390/ijms21051579 Authors: Yun Ji Wenzhen Yin Yuan Liang Lijun Sun Yue Yin Weizhen Zhang The cellular and molecular mechanisms by which indole-3-acetic acid (IAA), a tryptophan-derived metabolite from gut microbiota, attenuates inflammation and...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1577: Genomic Prediction Accuracy of Seven Breeding Selection Traits Improved by QTL Identification in Flax International Journal of Molecular Sciences doi: 10.3390/ijms21051577 Authors: Samuel Lan Chunfang Zheng Kyle Hauck Madison McCausland Scott D. Duguid Helen M. Booker Sylvie Cloutier Frank M. You Molecular markers are one of the major factors affecting genomic prediction accuracy and the cost of genomic selection (GS). Previous studies...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1578: Biomarkers of Liver Injury during Transplantation in an Era of Machine Perfusion International Journal of Molecular Sciences doi: 10.3390/ijms21051578 Authors: Ricky H. Bhogal Darius F. Mirza Simon C. Afford Hynek Mergental Liver ischaemia–reperfusion injury (IRI) is an intrinsic part of the transplantation process and damages the parenchymal cells of the liver including hepatocytes, endothelial cells and cholangiocytes. Many biomarkers of...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1573: Ethylene Biosynthesis Inhibition Combined with Cyanide Degradation Confer Resistance to Quinclorac in Echinochloa crus-galli var. mitis International Journal of Molecular Sciences doi: 10.3390/ijms21051573 Authors: Muhammad Zia Ul Zia Ul Haq Zheng Zhang Jiajia Wei Sheng Qiang Echinochloa crus-galli var. mitis has rarely been reported for herbicide resistance, and no case of quinclorac resistance has been reported so far. Synthetic auxin-type herbicide...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1575: Antioxidant Blueberry Anthocyanins Induce Vasodilation via PI3K/Akt Signaling Pathway in High-Glucose-Induced Human Umbilical Vein Endothelial Cells International Journal of Molecular Sciences doi: 10.3390/ijms21051575 Authors: Wuyang Huang Ruth Paulina Hutabarat Zhi Chai Tiesong Zheng Weimin Zhang Dajing Li Blueberries are rich in antioxidant anthocyanins. The hypotensive effects of blueberry anthocyanins in endothelial cells was investigated...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1574: Synergistic Upregulation of Target Genes by TET1 and VP64 in the dCas9–SunTag Platform International Journal of Molecular Sciences doi: 10.3390/ijms21051574 Authors: Sumiyo Morita Takuro Horii Mika Kimura Izuho Hatada Overexpression of a gene of interest is a general approach used in both basic research and therapeutic applications. However, the conventional approach involving overexpression of exogenous genes has difficulty achieving complete genome...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1576: Ticagrelor Increases SIRT1 and HES1 mRNA Levels in Peripheral Blood Cells from Patients with Stable Coronary Artery Disease and Chronic Obstructive Pulmonary Disease International Journal of Molecular Sciences doi: 10.3390/ijms21051576 Authors: Giorgio Aquila Francesco Vieceli Dalla Vieceli Dalla Sega Luisa Marracino Rita Pavasini Laura Sofia Cardelli Anna Piredda Alessandra Scoccia Valeria Martino Francesca Fortini Ilaria Bononi Fernanda...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1570: Deleterious Effect of NMDA Plus Kainate on the Inner Retinal Cells and Ganglion Cell Projection of the Mouse International Journal of Molecular Sciences doi: 10.3390/ijms21051570 Authors: Calvo Milla-Navarro Ortuño-Lizarán Gómez-Vicente Cuenca De la Villa Germain Combined administration of N-Methyl-D-Aspartate (NMDA) and kainic acid (KA) on the inner retina was studied as a model of excitotoxicity. The right eye of C57BL6J mice was...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1569: Elevated Systemic IL-10 Levels Indicate Immunodepression Leading to Nosocomial Infections after Aneurysmal Subarachnoid Hemorrhage (SAH) in Patients International Journal of Molecular Sciences doi: 10.3390/ijms21051569 Authors: Chaudhry Kahlert Kinfe Lamprecht Niemelä Hänggi Muhammad Background: Aneurysmal subarachnoid hemorrhage (SAH) is a highly complex disease with very high mortality and morbidity. About one-third of SAH patients...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1566: Transglutaminase 3 Reduces the Severity of Psoriasis in Imiquimod-Treated Mouse Skin International Journal of Molecular Sciences doi: 10.3390/ijms21051566 Authors: Piro Ventura Smirnov Saggini Lena Mauriello Bianchi Melino Candi Four transglutaminase (TG) isoforms have been detected in epidermal keratinocytes: TG1, TG2, TG3, and TG5. Except for TG1 and TG3, their contribution to keratinocyte development and structure remains...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1572: The Transcriptome of Pig Spermatozoa, and Its Role in Fertility International Journal of Molecular Sciences doi: 10.3390/ijms21051572 Authors: Alvarez-Rodriguez Martinez Wright Barranco Roca Rodriguez-Martinez In the study presented here we identified transcriptomic markers for fertility in the cargo of pig ejaculated spermatozoa using porcine-specific micro-arrays (GeneChip® miRNA 4.0 and GeneChip® Porcine Gene 1.0 ST)....
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1571: Corylifol A from Psoralea corylifolia L. Enhances Myogenesis and Alleviates Muscle Atrophy International Journal of Molecular Sciences doi: 10.3390/ijms21051571 Authors: Han Lee Li Ryu Inflammatory conditions caused by cancer, chronic diseases or aging can lead to skeletal muscle atrophy. We identified myogenic compounds from Psoralea corylifolia (PC), a medicinal plant that has been used for the treatment of inflammatory and skin diseases. C2C12...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1567: BDNF Expression in Cortical GABAergic Interneurons International Journal of Molecular Sciences doi: 10.3390/ijms21051567 Authors: Barreda Tomás Turko Heilmann Trimbuch Yanagawa Vida Münster-Wandowski Brain-derived neurotrophic factor (BDNF) is a major neuronal growth factor that is widely expressed in the central nervous system. It is synthesized as a glycosylated precursor protein, (pro)BDNF and post-translationally converted to the...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1565: Effects of SCCO2, Gamma Irradiation, and Sodium Dodecyl Sulfate Treatments on the Initial Properties of Tendon Allografts International Journal of Molecular Sciences doi: 10.3390/ijms21051565 Authors: Sun Lovric Wang Oliver Walsh Sterile and decellularized allograft tendons are viable biomaterials used in reconstructive surgeries for dense connective tissue injuries. Established allograft processing techniques including gamma irradiation and...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1561: Deviating from the Beaten Track: New Twists in Brassinosteroid Receptor Function International Journal of Molecular Sciences doi: 10.3390/ijms21051561 Authors: Wolf A key feature of plants is their plastic development tailored to the environmental conditions. To integrate environmental signals with genetic growth regulatory programs, plants rely on a number of hormonal pathways, which are intimately connected at multiple levels. Brassinosteroids (BRs), a class...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1564: Retrotransposons Manipulating Mammalian Skeletal Development in Chondrocytes International Journal of Molecular Sciences doi: 10.3390/ijms21051564 Authors: Kubota Ishikawa Kawata Hattori Nishida Retrotransposons are genetic elements that copy and paste themselves in the host genome through transcription, reverse-transcription, and integration processes. Along with their proliferation in the genome, retrotransposons inevitably modify host genes...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1563: Sewage Sludge ZnCl2-Activated Carbon Intercalated MgFe–LDH Nanocomposites: Insight of the Sorption Mechanism of Improved Removal of Phenol from Water International Journal of Molecular Sciences doi: 10.3390/ijms21051563 Authors: Mu’azu Zubair Jarrah Alagha Al-Harthi Essa Keywords: sludge-activated carbon; MgFe layered double hydroxide; nanocomposite materials; phenol aqueous uptake; mechanistic studies; reusability performance
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1562: Mut9p-LIKE KINASE Family Members: New Roles of the Plant-Specific Casein Kinase I in Plant Growth and Development International Journal of Molecular Sciences doi: 10.3390/ijms21051562 Authors: Kang Wang : Casein kinase I (CK1), a ubiquitous serine/threonine (Ser/Thr) protein kinase in eukaryotes, plays pivotal roles in a wide spectrum of cellular functions including metabolism, cell cycle progression, developmental control and stress responses. Plant CK1...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1568: Periodic Membrane Potential and Ca2+ Oscillations in T Cells Forming an Immune Synapse International Journal of Molecular Sciences doi: 10.3390/ijms21051568 Authors: Papp Hajdu Tajti Toth Nagy Fazekas Kovacs Vámosi Varga Panyi The immunological synapse (IS) is a specialized contact area formed between a T cell and an antigen presenting cell (APC). Besides molecules directly involved in antigen recognition such as the TCR/CD3...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1559: Podocyte Lysosome Dysfunction in Chronic Glomerular Diseases International Journal of Molecular Sciences doi: 10.3390/ijms21051559 Authors: Li Kidd Li Podocytes are visceral epithelial cells covering the outer surface of glomerular capillaries in the kidney. Blood is filtered through the slit diaphragm of podocytes to form urine. The functional and structural integrity of podocytes is essential for the normal function of the kidney. As a membrane-bound...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1558: The Effects of Essential Oils and Terpenes in Relation to Their Routes of Intake and Application International Journal of Molecular Sciences doi: 10.3390/ijms21051558 Authors: Koyama Heinbockel Essential oils have been used in multiple ways, i.e., inhaling, topically applying on the skin, and drinking. Thus, there are three major routes of intake or application involved: the olfactory system, the skin, and the gastro-intestinal system. Understanding these...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1557: Computational Models in Non-Coding RNA and Human Disease International Journal of Molecular Sciences doi: 10.3390/ijms21051557 Authors: Chen Wang Guan The central dogma of molecular biology has told that DNA sequences encode proteins through RNAs, which function as an information intermediary [...]
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1554: Obesity Affects the Microbiota–Gut–Brain Axis and the Regulation Thereof by Endocannabinoids and Related Mediators International Journal of Molecular Sciences doi: 10.3390/ijms21051554 Authors: Forte Fernández-Rilo Palomba Di Marzo Cristino The hypothalamus regulates energy homeostasis by integrating environmental and internal signals to produce behavioral responses to start or stop eating. Many satiation signals are mediated by microbiota-derived...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1560: Pathomechanisms of Posttraumatic Osteoarthritis: Chondrocyte Behavior and Fate in a Precarious Environment International Journal of Molecular Sciences doi: 10.3390/ijms21051560 Authors: Riegger Brenner Traumatic injuries of the knee joint result in a wide variety of pathomechanisms, which contribute to the development of so-called posttraumatic osteoarthritis (PTOA). These pathogenetic processes include oxidative stress, excessive expression of catabolic...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1553: Variability in HIV-1 Integrase Gene and 3’-Polypurine Tract Sequences in Cameroon Clinical Isolates, and Implications for Integrase Inhibitors Efficacy International Journal of Molecular Sciences doi: 10.3390/ijms21051553 Authors: Acharya Tagny Mbanya Fonsah Nchindap Kenmogne Jihyun Njamnshi Kanmogne : Integrase strand-transfer inhibitors (INSTIs) are now included in preferred first-line antiretroviral therapy (ART) for HIV-infected...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1552: Dynamics and Endocytosis of Flot1 in Arabidopsis Require CPI1 Function International Journal of Molecular Sciences doi: 10.3390/ijms21051552 Authors: Cao He Qi Zhang Lu Xue Li Li Membrane microdomains are nano-scale domains (10–200 nm) enriched in sterols and sphingolipids. They have many important biological functions, including vesicle transport, endocytosis, and pathogen invasion. A previous study reported that the...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1555: Cardiac Function is not Susceptible to Moderate Disassembly of Mitochondrial Respiratory Supercomplexes International Journal of Molecular Sciences doi: 10.3390/ijms21051555 Authors: Chapa-Dubocq Rodríguez-Graciani Guzmán-Hernández Jang Brookes Javadov : Mitochondrial respiratory chain supercomplexes (RCS), particularly, the respirasome, which contains complexes I, III, and IV, have been suggested to participate in facilitating electron...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1556: Low Doses of Methylmercury Induce the Proliferation of Thyroid Cells In Vitro Through Modulation of ERK Pathway International Journal of Molecular Sciences doi: 10.3390/ijms21051556 Authors: Maggisano Bulotta Celano Maiuolo Lepore Abballe Iannone Russo Exposure to environmental endocrine disruptors has been associated with an increased frequency of thyroid pathology. In this study, we evaluated the effects of various concentrations...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1551: Roles of Splicing Factors in Hormone-Related Cancer Progression International Journal of Molecular Sciences doi: 10.3390/ijms21051551 Authors: Takeiwa Mitobe Ikeda Horie-Inoue Inoue Splicing of mRNA precursor (pre-mRNA) is a mechanism to generate multiple mRNA isoforms from a single pre-mRNA, and it plays an essential role in a variety of biological phenomena and diseases such as cancers. Previous studies have demonstrated that cancer-specific...
Tue Feb 25, 2020 02:00
IJMS, Vol. 21, Pages 1550: In Silico Insights into Protein–protein Interaction Disruptive Mutations in the PCSK9-LDLR complex International Journal of Molecular Sciences doi: 10.3390/ijms21051550 Authors: William R. Martin Felice C. Lightstone Feixiong Cheng Gain-of-function mutations in PCSK9 (proprotein convertase subtilisin/kexin type 9) lead to reduced uptake of LDL (low density lipoprotein) cholesterol and, therefore, increased plasma LDL levels. However, the mechanism by...
Tue Feb 25, 2020 02:00
JCM, Vol. 9, Pages 620: Magnesium Sulfate Treatment During Total Knee Arthroplasty Decreases Postoperative Urinary Retention: A Retrospective Propensity Score-Matched Analysis Journal of Clinical Medicine doi: 10.3390/jcm9030620 Authors: Jin-Woo Park Eun-Kyoung Kim Dongsik Lim Tak Kyu Oh Seongjoo Park Sang-Hwan Do Postoperative urinary retention (POUR) is a common complication after total knee arthroplasty. Currently, there are no clinical data regarding the effects of...
Tue Feb 25, 2020 02:00
JCM, Vol. 9, Pages 617: Menstrual Cycle Changes in Vagally-Mediated Heart Rate Variability are Associated with Progesterone: Evidence from Two Within-Person Studies Journal of Clinical Medicine doi: 10.3390/jcm9030617 Authors: Schmalenberger Eisenlohr-Moul Jarczok Eckstein Schneider Brenner Duffy Schweizer Kiesner Thayer Ditzen A recent meta-analysis revealed that cardiac vagal activity (mostly indicated by vagally-mediated heart rate variability;...
Tue Feb 25, 2020 02:00
JCM, Vol. 9, Pages 619: Robust Association between Acute Kidney Injury after Radical Nephrectomy and Long-term Renal Function Journal of Clinical Medicine doi: 10.3390/jcm9030619 Authors: Won Ho Kim Kyung Won Shin Sang-Hwan Ji Young-Eun Jang Ji-Hyun Lee Chang Wook Jeong Cheol Kwak Young-Jin Lim The association between acute kidney injury (AKI) and long-term renal function after radical nephrectomy has not been evaluated fully. We reviewed 558 cases of radical nephrectomy....
Tue Feb 25, 2020 02:00
JCM, Vol. 9, Pages 621: Non-Pharmacological Interventions for Post-Stroke Fatigue: Systematic Review and Network Meta-Analysis Journal of Clinical Medicine doi: 10.3390/jcm9030621 Authors: Ya Su Michiko Yuki Mika Otsuki Post-stroke fatigue (PSF) is one of the most serious sequelae, which often interferes with the rehabilitation process and impairs the functional recovery of patients. Due to insufficient evidence, it is unclear which specific pharmacological interventions should...
Tue Feb 25, 2020 02:00
JCM, Vol. 9, Pages 618: OVOL2-Mediated ZEB1 Downregulation May Prevent Promotion of Actinic Keratosis to Cutaneous Squamous Cell Carcinoma Journal of Clinical Medicine doi: 10.3390/jcm9030618 Authors: Maho Murata Takamichi Ito Yuka Tanaka Kazuhiko Yamamura Kazuhisa Furue Masutaka Furue Progression of actinic keratosis (AK) to cutaneous squamous cell carcinoma (cSCC) is rare. Most cases of AK remain as intraepidermal lesions, owing to the suppression of the epithelial-to-mesenchymal...
Tue Feb 25, 2020 02:00
JCM, Vol. 9, Pages 616: Neuropathophysiology of Lysosomal Storage Diseases: Synaptic Dysfunction as a Starting Point for Disease Progression Journal of Clinical Medicine doi: 10.3390/jcm9030616 Authors: Camila Pará Poulomee Bose Alexey V. Pshezhetsky About two thirds of the patients affected with lysosomal storage diseases (LSD) experience neurological manifestations, such as developmental delay, seizures, or psychiatric problems. In order to develop efficient therapies, it is...
Tue Feb 25, 2020 02:00
JCM, Vol. 9, Pages 615: Life Expectancy after Surgery for Ascending Aortic Aneurysm Journal of Clinical Medicine doi: 10.3390/jcm9030615 Authors: Hernandez-Vaquero Silva Escalera Álvarez-Cabo Morales Díaz Avanzas Moris Pascual Introduction: The life expectancy of patients who undergo ascending aortic replacement is unknown. The life expectancy of a population depends on a collection of environmental and socio-economic factors of the territory where they...
Tue Feb 25, 2020 02:00
JCM, Vol. 9, Pages 614: Heart Failure Is a Risk Factor for Suffering and Dying of Clostridium difficile Infection. Results of a 15-Year Nationwide Study in Spain Journal of Clinical Medicine doi: 10.3390/jcm9030614 Authors: Manuel Méndez-Bailón Rodrigo Jiménez-García Valentín Hernández-Barrera Javier de Miguel-Díez José M. de Miguel-Yanes Nuria Muñoz-Rivas Noel Lorenzo-Villalba David Carabantes-Alarcon José J. Zamorano-León Paloma Astasio-Arbiza Paloma Ortega-Molina...
Tue Feb 25, 2020 02:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου