Related Articles[Effect of electronic moxibustion on activity of parapharyngeal wall in patients with achalasia of cricopharyngeus muscle after stroke based on musculoskeletal ultrasound]. Zhongguo Zhen Jiu. 2020 Feb 12;40(2):119-22 Authors: Ruan CL, Lin ZH, Huang M, Chen RL Abstract OBJECTIVE: To observe the clinical effect of electronic moxibustion on dysphagia in patients with achalasia of cricopharyngeus muscle after stroke. METHODS: Sixty...
Thu Feb 27, 2020 13:56
Related ArticlesCoordination of tongue pressure production, hyoid movement, and suprahyoid muscle activity during squeezing of gels. Arch Oral Biol. 2020 Mar;111:104631 Authors: Murakami K, Hori K, Minagi Y, Uehara F, Salazar SE, Ishihara S, Nakauma M, Funami T, Ikebe K, Maeda Y, Ono T Abstract OBJECTIVE: The aim of this study was to evaluate tongue movement and its biomechanical effects during squeezing, one of the oral strategies for processing soft...
Thu Feb 27, 2020 13:56
Nature Communications, Published online: 27 February 2020; doi:10.1038/s41467-020-14855-3In vivo reprogramming of reactive glia using transfection of a single transcription factor has been described before by these authors and applied to models of neurodegeneration. Here the authors use this procedure in the R6/2 mouse model of Huntington’s disease, targeting astrocytes in the striatum, converting them to GABAergic neurons.
Thu Feb 27, 2020 02:00
Nature Communications, Published online: 27 February 2020; doi:10.1038/s41467-020-14852-6Palm oil biofuels are touted as a sustainable alternative to fossil fuels. Meijide and colleagues use greenhouse gas measurements to update life cycle assessments of oil palm growth scenarios and show that despite the promise, emission savings do not meet sustainability standards.
Thu Feb 27, 2020 02:00
Nature Communications, Published online: 27 February 2020; doi:10.1038/s41467-020-14892-yIncorporation of supramolecular macrocycles into porous organic polymers can increase uptake of guest molecules through host−guest interactions. Here the authors report a pillar[5]quinone derived multi-microporous organic polymer, which show a superior performance in radioactive iodomethane capture and storage.
Thu Feb 27, 2020 02:00
Nature Communications, Published online: 27 February 2020; doi:10.1038/s41467-020-14786-zStructural and molecular elucidation of cerebrovascular network is promising for understanding energy supply system in the brain. Here, the authors describe labeling and tissue clearing techniques that visualize the whole-brain vasculature in a molecularly characterizable manner.
Thu Feb 27, 2020 02:00
Nature Communications, Published online: 27 February 2020; doi:10.1038/s41467-020-14897-7Interaural timing and level differences had been considered the two important cues for horizontal sound localization. Here, the authors show that the third cue, spectral information, plays an essential role in the encoding of the azimuthal auditory map in the mouse superior colliculus.
Thu Feb 27, 2020 02:00
Nature Communications, Published online: 27 February 2020; doi:10.1038/s41467-020-14791-2GWAS analysis currently relies mostly on linear mixed models, which do not account for linkage disequilibrium (LD) between tested variants. Here, Sesia et al. propose KnockoffZoom, a non-parametric statistical method for the simultaneous discovery and fine-mapping of causal variants, assuming only that LD is described by hidden Markov models (HMMs).
Thu Feb 27, 2020 02:00
A comparative genomics methodology reveals a widespread family of membrane-disrupting T6SS effectors
Nature Communications, Published online: 27 February 2020; doi:10.1038/s41467-020-14951-4Gram-negative bacteria deliver effectors via the type VI secretion system (T6SS) to outcompete their rivals. Here, Fridman et al. present an approach to identify T6SS effectors encoded in bacterial genomes without prior knowledge of their domain content or genetic neighbourhood, and identify a new family of membrane-disrupting effectors.
Thu Feb 27, 2020 02:00
Nature Communications, Published online: 27 February 2020; doi:10.1038/s41467-019-14051-yAspergillus fungi classified within the section Flavi include harmful and beneficial species. Here, Kjærbølling et al. analyse the genomes of 23 Flavi species, showing high genetic diversity and potential for synthesis of over 13,700 CAZymes and 1600 secondary metabolites.
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A comparative genomics methodology reveals a widespread family of membrane-disrupting T6SS effectors
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Related ArticlesDown-regulation of anti-inflammatory TIPE2 may aggravate adenoidal hypertrophy in children. FEBS Open Bio. 2020 Feb 25;: Authors: Gao K, Li Y, Yue Z, Han J, Zhou X, Wang X Abstract Adenoidal hypertrophy (AH) is a common disorder in the pediatric population, with common symptoms including mouth breathing, nasal congestion, hyponasal speech, snoring, and obstructive sleep apnea (OSA). Although the pathogenesis of AH has not been fully elucidated,...
Thu Feb 27, 2020 13:51
Related Articles[Sleep-disordered breathing as a consequence of vagus nerve stimulation]. Rev Neurol. 2020 Mar 01;70(5):179-182 Authors: Pérez-Carbonell L, Higgins S, Koutroumanidis M, Leschziner G Abstract INTRODUCTION: Vagus nerve stimulation (VNS) is indicated in cases of refractory epilepsy. Its side effects are frequently minor, however, breathing disturbances during sleep have been previously reported. CASE REPORTS: Our three cases are...
Thu Feb 27, 2020 13:51
Related ArticlesComparison of sleep structure in patients with fibromyalgia and healthy controls. Sleep Breath. 2020 Feb 25;: Authors: Çetin B, Sünbül EA, Toktaş H, Karaca M, Ulutaş Ö, Güleç H Abstract BACKGROUND: Sleep disturbances such as nonrestorative sleep and nighttime awakenings play a crucial role in fibromyalgia (FMS). Pain and sleep disturbances show a bidirectional relationship which affect outcomes in FMS. This study aims to compare sleep...
Thu Feb 27, 2020 13:51
Related ArticlesMandibular Advancement Devices Prevent the Adverse Cardiac Effects of Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS). Sci Rep. 2020 Feb 25;10(1):3394 Authors: Liu C, Kang W, Zhang S, Qiao X, Yang X, Zhou Z, Lu H Abstract Although considerable research highlights the interactions between obstructive sleep apnea-hypopnea syndrome (OSAHS) and cardiovascular diseases, the effect of mandibular advancement device (MAD) treatment on cardiovascular...
Thu Feb 27, 2020 13:51
Related ArticlesSleep Apnea, Hypertension and the Sympathetic Nervous System in the Adult Population. J Clin Med. 2020 Feb 21;9(2): Authors: Venkataraman S, Vungarala S, Covassin N, Somers VK Abstract Sleep apnea is very common in patients with cardiovascular disease, especially in patients with hypertension. Over the last few decades a number of discoveries have helped support a causal relationship between the two and even resistant hypertension. The...
Thu Feb 27, 2020 13:51
Related ArticlesATP Synthase Subunit a Supports Permeability Transition in Yeast Lacking Dimerization Subunits and Modulates yPTP Conductance. Cell Physiol Biochem. 2020 Feb 27;54(2):211-229 Authors: Niedzwiecka K, Baranowska E, Panja C, Kucharczyk R Abstract BACKGROUND/AIMS: Mitochondrial ATP synthase, in addition to being involved in ATP synthesis, is involved in permeability transition pore (PTP) formation, which precedes apoptosis in mammalian cells...
Thu Feb 27, 2020 13:51
Related ArticlesVestibular Schwannoma Causing Unilateral Facial Pain in 20-Year-Old Patient. Ear Nose Throat J. 2020 Feb 26;:145561320908479 Authors: Fahmy A, Mahmood A PMID: 32100559 [PubMed - as supplied by publisher]
Thu Feb 27, 2020 13:51
Related ArticlesRisk Factors for Pharyngocutaneous Fistula After Total Pharyngolaryngectomy. Ear Nose Throat J. 2020 Feb 25;:145561319901035 Authors: Lemaire E, Schultz P, Vergez S, Debry C, Sarini J, Vairel B, de Bonnecaze G, Takeda-Raguin C, Cabarrou B, Dupret-Bories A Abstract PURPOSE: To evaluate the risk factors of pharyngocutaneous fistula after total pharyngolaryngectomy (TPL) in order to reduce their incidence and propose a perioperative rehabilitation...
Thu Feb 27, 2020 13:51
Related ArticlesFrontiers in antiviral therapy and immunotherapy. Clin Transl Immunology. 2020;9(2):e1115 Authors: Heaton SM PMID: 32099652 [PubMed]
Thu Feb 27, 2020 13:50
Related ArticlesPerioperative Management of Patients With Hereditary Angioedema With Special Considerations for Cardiopulmonary Bypass. Anesth Analg. 2020 Feb 24;: Authors: Tanaka KA, Mondal S, Morita Y, Williams B, Strauss ER, Cicardi M Abstract Hereditary angioedema (HAE) is a rare autosomal dominant disorder mostly due to the deficiency of C1-esterase inhibitor (C1-INH). Reduced C1-INH activity below ~38% disrupts homeostasis of bradykinin (BK) formation...
Thu Feb 27, 2020 13:49
Related Articles[Effect of laryngeal closure on recurrent aspiration pneumonia in patients with neurodegenerative disease]. Rinsho Shinkeigaku. 2020 Feb 26;: Authors: Osako M, Saigusa H, Takeuchi C, Minatogawa M, Mochizuki Y Abstract Three patients with neurodegenerative diseases who had developed repeated aspiration pneumonia underwent laryngeal closure, a surgical procedure at the larynx to prevent aspiration. None of these patients have developed...
Thu Feb 27, 2020 13:49
Related ArticlesSuckling, Feeding, and Swallowing: Behaviors, Circuits, and Targets for Neurodevelopmental Pathology. Annu Rev Neurosci. 2020 Feb 26;: Authors: Maynard TM, Zohn IE, Moody SA, LaMantia AS Abstract All mammals must suckle and swallow at birth, and subsequently chew and swallow solid foods, for optimal growth and health. These initially innate behaviors depend critically upon coordinated development of the mouth, tongue, pharynx, and larynx...
Thu Feb 27, 2020 13:49
Related ArticlesEpiglottic granular cell tumour: a case report and literature review. J Surg Case Rep. 2020 Feb;2020(2):rjaa009 Authors: Bouayyad S, Ong J, Bouayyad H, Woodun H Abstract Granular cell tumour is a rare, benign tumour that may arise in the soft tissues of various locations. It is often asymptomatic; hence, it gets misdiagnosed as other conditions. This is a case of an asymptomatic 50-year-old male with an incidental finding of a supraglottic...
Thu Feb 27, 2020 13:49
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