IJMS, Vol. 21, Pages 1423: Targeting Peripherally Restricted Cannabinoid Receptor 1, Cannabinoid Receptor 2, and Endocannabinoid-Degrading Enzymes for the Treatment of Neuropathic Pain Including Neuropathic Orofacial Pain International Journal of Molecular Sciences doi: 10.3390/ijms21041423 Authors: Hossain Ando Unno Kitagawa Neuropathic pain conditions including neuropathic orofacial pain (NOP) are difficult to treat. Contemporary therapeutic agents for neuropathic pain...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1421: Homocysteine: Its Possible Emerging Role in At-Risk Population Groups International Journal of Molecular Sciences doi: 10.3390/ijms21041421 Authors: Elena Azzini Stefania Ruggeri Angela Polito Increased plasma homocysteine is a risk factor for several pathological disorders. The present review focused on the role of homocysteine (Hcy) in different population groups, especially in risk conditions (pregnancy, infancy, old age), and on its relevance as a...
Thu Feb 20, 2020 02:00
IJMS, Vol. 21, Pages 1422: Plant Lipid Bodies Traffic on Actin to Plasmodesmata Motorized by Myosin XIs International Journal of Molecular Sciences doi: 10.3390/ijms21041422 Authors: Veerabagu K Paul Rinne van der Schoot Late 19th-century cytologists observed tiny oil drops in shoot parenchyma and seeds, but it was discovered only in 1972 that they were bound by a half unit-membrane. Later, it was found that lipid bodies (LBs) arise from the endoplasmic reticulum. Seeds...
Thu Feb 20, 2020 02:00
JCM, Vol. 9, Pages 580: Communicating the Risk of Death from Novel Coronavirus Disease (COVID-19) Journal of Clinical Medicine doi: 10.3390/jcm9020580 Authors: Tetsuro Kobayashi Sung-mok Jung Natalie M. Linton Ryo Kinoshita Katsuma Hayashi Takeshi Miyama Asami Anzai Yichi Yang Baoyin Yuan Andrei R. Akhmetzhanov Ayako Suzuki Hiroshi Nishiura To understand the severity of infection for a given disease, it is common epidemiological practice to estimate the...
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JCM, Vol. 9, Pages 579: Relationships Among and Predictive Values of Obesity, Inflammation Markers, and Disease Severity in Pediatric Patients with Obstructive Sleep Apnea Before and After Adenotonsillectomy Journal of Clinical Medicine doi: 10.3390/jcm9020579 Authors: Hai-Hua Chuang Chung-Guei Huang Li-Pang Chuang Yu-Shu Huang Ning-Hung Chen Hsueh-Yu Li Tuan-Jen Fang Jen-Fu Hsu Hsin-Chih Lai Jau-Yuan Chen Li-Ang Lee Both obstructive sleep apnea (OSA) and...
Thu Feb 20, 2020 02:00
JCM, Vol. 9, Pages 573: Identification of Clonality Through Genomic Profile Analysis in Multiple Lung Cancers Journal of Clinical Medicine doi: 10.3390/jcm9020573 Authors: Higuchi Nakagomi Goto Hirotsu Shikata Yokoyama Otake Amemiya Oyama Mochizuki Omata In cases of multiple lung cancers, individual tumors may represent either a primary lung cancer or both primary and metastatic lung cancers. In this study, we investigated the differences between...
Thu Feb 20, 2020 02:00
JCM, Vol. 9, Pages 577: Sex-Sparing Robot-Assisted Radical Cystectomy with Intracorporeal Padua Ileal Neobladder in Female: Surgical Technique, Perioperative, Oncologic and Functional Outcomes Journal of Clinical Medicine doi: 10.3390/jcm9020577 Authors: Gabriele Tuderti Riccardo Mastroianni Simone Flammia Mariaconsiglia Ferriero Costantino Leonardo Umberto Anceschi Aldo Brassetti Salvatore Guaglianone Michele Gallucci Giuseppe Simone Our aim was to illustrate...
Thu Feb 20, 2020 02:00
JCM, Vol. 9, Pages 576: Surgical Outcomes of Secondary Alveolar Bone Grafting and Extensive Gingivoperiosteoplasty Performed at Mixed Dentition Stage in Unilateral Complete Cleft Lip and Palate Journal of Clinical Medicine doi: 10.3390/jcm9020576 Authors: Yu-Ying Chu Frank Chun-Shin Chang Ting-Chen Lu Che-Hsiung Lee Philip Kuo-Ting Chen Secondary alveolar bone grafting (SABG) is associated with donor site morbidities. We aimed to compare the outcomes of SABG and extensive...
Thu Feb 20, 2020 02:00
JCM, Vol. 9, Pages 578: Classic and Novel Biomarkers as Potential Predictors of Ventricular Arrhythmias and Sudden Cardiac Death Journal of Clinical Medicine doi: 10.3390/jcm9020578 Authors: Shomanova Ohnewein Schernthaner Höfer Pogoda Frommeyer Wernly Brandt Dieplinger Reinecke Hoppe Strohmer Pistulli Motloch Sudden cardiac death (SCD), most often induced by ventricular arrhythmias, is one of the main reasons for cardiovascular-related...
Thu Feb 20, 2020 02:00
JCM, Vol. 9, Pages 575: Characteristics of and Public Health Responses to the Coronavirus Disease 2019 Outbreak in China Journal of Clinical Medicine doi: 10.3390/jcm9020575 Authors: Sheng-Qun Deng Hong-Juan Peng In December 2019, cases of unidentified pneumonia with a history of exposure in the Huanan Seafood Market were reported in Wuhan, Hubei Province. A novel coronavirus, SARS-CoV-2, was identified to be accountable for this disease. Human-to-human transmission is confirmed,...
Thu Feb 20, 2020 02:00
JCM, Vol. 9, Pages 574: Preeclampsia: The Interplay Between Oxygen-Sensitive miRNAs and Erythropoietin Journal of Clinical Medicine doi: 10.3390/jcm9020574 Authors: Vladislava Gusar Angelika Timofeeva Vitaliy Chagovets Nataliya Kan Oksana Vasilchenko Kseniya Prozorovskaya Tatyana Ivanets Gennadiy Sukhikh Changes in the oxygen partial pressure caused by a violation of uteroplacental perfusion are considered a powerful inducer of a cascade of reactions leading to the...
Thu Feb 20, 2020 02:00
JFB, Vol. 11, Pages 10: Synthesis and Properties of Zinc-Modified Hydroxyapatite Journal of Functional Biomaterials doi: 10.3390/jfb11010010 Authors: Daria Lytkina Anastasiya Gutsalova Dmitriy Fedorishin Natalya Korotchenko Rafik Akhmedzhanov Vladimir Kozik Irina Kurzina Hydroxyapatites modified with metal ions are the main inorganic components of bone tissue and are approved for use as components for biocomposites and coatings for surgical implants. This study examined...
Thu Feb 20, 2020 02:00
Medicina, Vol. 56, Pages 86: Timing between Breast Reconstruction and Oncologic Mastectomy—One Center Experience Medicina doi: 10.3390/medicina56020086 Authors: Adelaida Avino Laura Răducu Lăcrămioara Aurelia Brînduşe Cristian-Radu Jecan Ioan Lascăr Background and objectives: Breast cancer is the most common cancer in women. The immunohistochemical profile, but also the stage of the tumor determines the therapeutic management, which varies from conservative surgery to mastectomy...
Thu Feb 20, 2020 02:00
Medicines, Vol. 7, Pages 9: Efficacy of Antihypertensive Therapy in a Child with Unilateral Focal Fibromuscular Dysplasia of the Renal Artery: A Case Study and Review of Literature Medicines doi: 10.3390/medicines7020009 Authors: Ratna Acharya Savannah Ellenwood Kiran Upadhyay Background: Fibromuscular dysplasia (FMD) is one of the important etiologies of renovascular hypertension in children. It is usually resistant to multiple antihypertensive agents and can cause extreme elevation...
Thu Feb 20, 2020 02:00
Metabolites, Vol. 10, Pages 77: The Determinants of the Human Milk Metabolome and Its Role in Infant Health Metabolites doi: 10.3390/metabo10020077 Authors: Anna Ojo-Okunola Stefano Cacciatore Mark P. Nicol Elloise du du Toit Human milk is needed for optimal growth as it satisfies both the nutritional and biological needs of an infant. The established relationship between breastfeeding and an infant’s health is attributable to the nutritional and non-nutritional, functional...
Thu Feb 20, 2020 02:00
Metabolites, Vol. 10, Pages 76: Independent and Opposite Associations Between Branched-Chain Amino Acids and Lysophosphatidylcholines With Incident Diabetes in Thais Metabolites doi: 10.3390/metabo10020076 Authors: La-or Chailurkit Nitchawat Paiyabhroma Piyamit Sritara Prin Vathesatogkit Sukit Yamwong Nisakron Thonmung Boonsong Ongphiphadhanakul Branched-chain amino acids (BCAAs) and lysophosphatidylcholines (LPCs) have been reported to be associated with diabetes....
Thu Feb 20, 2020 02:00
MPs, Vol. 3, Pages 17: Determining the Age of Terrace Formation Using Luminescence Dating—A Case of the Yellow River Terraces in the Baode Area, China Methods and Protocols doi: 10.3390/mps3010017 Authors: Jia-Fu Zhang Wei-Li Qiu Gang Hu Li-Ping Zhou Dating fluvial terraces has long been a challenge for geologists and geomorphologists, because terrace straths and treads are not usually directly dated. In this study, the formation ages of the Yellow River terraces in the Baode...
Thu Feb 20, 2020 02:00
Microorganisms, Vol. 8, Pages 296: DNA Methylation Changes Induced by Cold in Psychrophilic and Psychrotolerant Naganishia Yeast Species Microorganisms doi: 10.3390/microorganisms8020296 Authors: Benedetta Turchetti Gianpiero Marconi Ciro Sannino Pietro Buzzini Emidio Albertini The involvement of DNA methylation in the response to cold stress of two different yeast species (Naganishia antarctica, psychrophilic, and Naganishia albida, psychrotolerant), exhibiting different...
Thu Feb 20, 2020 02:00
Microorganisms, Vol. 8, Pages 288: Antimicrobial Resistance in Members of the Bacterial Bovine Respiratory Disease Complex Isolated from Lung Tissue of Cattle Mortalities Managed with or without the Use of Antimicrobials Microorganisms doi: 10.3390/microorganisms8020288 Authors: Kim Stanford Rahat Zaheer Cassidy Klima Tim McAllister Delores Peters Yan D. Niu Brenda Ralston Over a two-year period, Mannheimia haemolytica (MH; n = 113), Pasteurella multocida (PM; n = 47),...
Thu Feb 20, 2020 02:00
Microorganisms, Vol. 8, Pages 291: A Rotational Slurry Bioreactor Accelerates Biodegradation of A-fuel in Oil-Contaminated Soil even under Low Temperature Conditions Microorganisms doi: 10.3390/microorganisms8020291 Authors: Yuna Miyoshi Jo Okada Tomotaka Urata Masaki Shintani Kazuhide Kimbara An effective bioaugmentation system for oil-contaminated soil under low-temperature conditions was developed with a rotational slurry bioreactor. Mixtures of two Rhodococcus oil-degraders,...
Thu Feb 20, 2020 02:00
Microorganisms, Vol. 8, Pages 295: Proteomic and Transcriptional Profiles of Human Stem Cell-Derived β Cells Following Enteroviral Challenge Microorganisms doi: 10.3390/microorganisms8020295 Authors: Julius O. Nyalwidhe Agata Jurczyk Basanthi Satish Sambra Redick Natasha Qaisar Melanie I. Trombly Pranitha Vangala Riccardo Racicot Rita Bortell David M. Harlan Dale L. Greiner Michael A. Brehm Jerry L. Nadler Jennifer P. Wang Enteroviral infections...
Thu Feb 20, 2020 02:00
Microorganisms, Vol. 8, Pages 292: Construction of a Tetracycline Degrading Bacterial Consortium and Its Application Evaluation in Laboratory-Scale Soil Remediation Microorganisms doi: 10.3390/microorganisms8020292 Authors: Xueling Wu Yichao Gu Xiaoyan Wu Xiangyu Zhou Han Zhou Charles Amanze Li Shen Weimin Zeng As an environmental pollutant, tetracycline (TC) can persist in the soil for years and damage the ecosystem. So far, many methods have been developed to handle...
Thu Feb 20, 2020 02:00
Microorganisms, Vol. 8, Pages 293: Discovery of Two Brominated Oxindole Alkaloids as Staphylococcal DNA Gyrase and Pyruvate Kinase Inhibitors via Inverse Virtual Screening Microorganisms doi: 10.3390/microorganisms8020293 Authors: Ahmed M. Sayed Hani A. Alhadrami Seham S. El-Hawary Rabab Mohammed Hossam M. Hassan Mostafa E. Rateb Usama Ramadan Abdelmohsen Walid Bakeer In the present study, a small marine-derived natural products library was assessed for antibacterial...
Thu Feb 20, 2020 02:00
Microorganisms, Vol. 8, Pages 290: Scientific Prospects for Cannabis-Microbiome Research to Ensure Quality and Safety of Products Microorganisms doi: 10.3390/microorganisms8020290 Authors: Vladimir Vujanovic Darren R. Korber Silva Vujanovic Josko Vujanovic Suha Jabaji Cannabis legalization has occurred in several countries worldwide. Along with steadily growing research in Cannabis healthcare science, there is an increasing interest for scientific-based knowledge in plant...
Thu Feb 20, 2020 02:00
Microorganisms, Vol. 8, Pages 289: Human Cytomegalovirus (HCMV) Reactivation in the Mammary Gland Induces a Proinflammatory Cytokine Shift in Breast Milk Microorganisms doi: 10.3390/microorganisms8020289 Authors: Tabea Rabe Katrin Lazar Christoffer Cambronero Rangmar Goelz Klaus Hamprecht A locally restricted human cytomegalovirus (HCMV) reactivation in the mammary gland commonly occurs in nearly every IgG-seropositive breastfeeding mother. This unique phenomenon can therefore...
Thu Feb 20, 2020 02:00
Microorganisms, Vol. 8, Pages 294: Occurrence, Diversity of Listeria spp. Isolates from Food and Food-Contact Surfaces and the Presence of Virulence Genes Microorganisms doi: 10.3390/microorganisms8020294 Authors: Rossi Amadoro Conficoni Giaccone Colavita This study evaluates the hazards posed by foodborne bacteria of the Listeria genus by analyzing the occurrence, diversity and virulence of Listeria spp.in food and food-manufacturing plants. Seventy-five isolates obtained...
Thu Feb 20, 2020 02:00
Microorganisms, Vol. 8, Pages 287: Colistin-Resistant Acinetobacter Baumannii Bacteremia: A Serious Threat for Critically Ill Patients Microorganisms doi: 10.3390/microorganisms8020287 Authors: Georgios Papathanakos Ioannis Andrianopoulos Athanasios Papathanasiou Efthalia Priavali Despoina Koulenti Vasilios Koulouras The prevalence of acinetobacter baumannii (AB) as a cause of hospital infections has been rising. Unfortunately, emerging colistin resistance limits therapeutic...
Thu Feb 20, 2020 02:00
Microorganisms, Vol. 8, Pages 286: pH and Phosphate Induced Shifts in Carbon Flow and Microbial Community during Thermophilic Anaerobic Digestion Microorganisms doi: 10.3390/microorganisms8020286 Authors: Nina Lackner Andreas O. Wagner Rudolf Markt Paul Illmer pH is a central environmental factor influencing CH4 production from organic substrates, as every member of the complex microbial community has specific pH requirements. Here, we show how varying pH conditions (5.0–8.5,...
Thu Feb 20, 2020 02:00
Molecules, Vol. 25, Pages 968: Isolation and Purification of Glucans from an Italian Cultivar of Ziziphus jujuba Mill. and In Vitro Effect on Skin Repair Molecules doi: 10.3390/molecules25040968 Authors: Alessia Fazio Chiara La Torre Maria Cristina Caroleo Paolino Caputo Pierluigi Plastina Erika Cione Glucans possess a broad spectrum of biological activities. In this context, the present study was performed to isolate glucans from an Italian cultivar of Ziziphus jujuba...
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Molecules, Vol. 25, Pages 966: A Step-by-Step Guide for the Novel Radiometal Production for Medical Applications: Case Studies with 68Ga, 44Sc, 177Lu and 161Tb Molecules doi: 10.3390/molecules25040966 Authors: Zeynep Talip Chiara Favaretto Susanne Geistlich Nicholas P. van der Meulen The production of novel radionuclides is the first step towards the development of new effective radiopharmaceuticals, and the quality thereof directly affects the preclinical and clinical phases....
Thu Feb 20, 2020 02:00
Molecules, Vol. 25, Pages 967: Chemical Composition, Algicidal, Antimicrobial, and Antioxidant Activities of the Essential Oils of Taiwania flousiana Gaussen Molecules doi: 10.3390/molecules25040967 Authors: Hongmei Liu Jiguang Huang Sifan Yang Jialin Li Lijuan Zhou Taiwania flousiana (T. flousiana) Gaussen is a precious wood in the family Taxodiaceae. This study investigated the chemical components of the essential oil from the stem bark of T. flousiana and its algicidal,...
Thu Feb 20, 2020 02:00
Molecules, Vol. 25, Pages 964: Bersavine: A Novel Bisbenzylisoquinoline Alkaloid with Cytotoxic, Antiproliferative and Apoptosis‐ Inducing Effects on Human Leukemic Cells Molecules doi: 10.3390/molecules25040964 Authors: Koutova Kulhava Havelek Majorosova Královec Habartova Hošťálková Opletal Cahlikova Řezáčová Bersavine is the new bisbenzylisoquinoline alkaloid isolated from the Berberis vulgaris L.(Berberidaceae) plant. The results of cytotoxicity...
Thu Feb 20, 2020 02:00
Molecules, Vol. 25, Pages 963: Discovery of Antifungal and Biofilm Preventative Compounds from Mycelial Cultures of a Unique North American Hericium sp. Fungus Molecules doi: 10.3390/molecules25040963 Authors: Xun Song François Gaascht Claudia Schmidt-Dannert Christine E. Salomon Edible mushrooms are an important source of nutraceuticals and for the discovery of bioactive metabolites as pharmaceuticals. In this work, the OSMAC (One Strain, Many Active Compounds) approach was...
Thu Feb 20, 2020 02:00
Molecules, Vol. 25, Pages 962: Exploration of Rapid Evaporative-Ionization Mass Spectrometry as a Shotgun Approach for the Comprehensive Characterization of Kigelia Africana (Lam) Benth. Fruit Molecules doi: 10.3390/molecules25040962 Authors: Katia Arena Francesca Rigano Domenica Mangraviti Francesco Cacciola Francesco Occhiuto Laura Dugo Paola Dugo Luigi Mondello Rapid evaporative-ionization mass spectrometry (REIMS) coupled with an electroknife as a sampling device...
Thu Feb 20, 2020 02:00
Molecules, Vol. 25, Pages 965: Alpha-Glucosidase- and Lipase-Inhibitory Phenalenones from a New Species of Pseudolophiostoma Originating from Thailand Molecules doi: 10.3390/molecules25040965 Authors: Allan Patrick G. Macabeo Luis Agustin E. Pilapil Katherine Yasmin M. Garcia Mark Tristan J. Quimque Chayanard Phukhamsakda Allaine Jean C. Cruz Kevin D. Hyde Marc Stadler The alpha-glucosidase- and lipase-inhibitory activities of three phenalenones (1–3) and...
Thu Feb 20, 2020 02:00
Molecules, Vol. 25, Pages 957: Probing Reversible Guest Binding with Hyperpolarized 129Xe-NMR: Characteristics and Applications for Cucurbit[n]urils Molecules doi: 10.3390/molecules25040957 Authors: Jabadurai Jayapaul Leif Schröder Cucurbit[n]urils (CB[n]s) are a family of macrocyclic host molecules that find various applications in drug delivery, molecular switching, and dye displacement assays. The CB[n]s with n = 5–7 have also been studied with 129Xe-NMR. They bind the...
Thu Feb 20, 2020 02:00
Molecules, Vol. 25, Pages 960: Metal Organic Frameworks: Synthesis and Application Molecules doi: 10.3390/molecules25040960 Authors: Samanidou Deliyanni The concept of metal–organic frameworks (MOFs) was first introduced in 1990; nowadays they are among the most promising novel materials. MOFs belong to a new class of crystalline materials that consist of coordination bonds between metal clusters (e.g., metal-carboxylate clusters and metal-azolate clusters), metal atoms,...
Thu Feb 20, 2020 02:00
Molecules, Vol. 25, Pages 959: Unsymmetrical 1,1-Bisboryl Species: Valuable Building Blocks in Synthesis Molecules doi: 10.3390/molecules25040959 Authors: K. Naresh Babu Fedaa Massarwe Rajasekhar Reddy Nadim Eghbarieh Manuella Jakob Ahmad Masarwa Unsymmetrical 1,1-bis(boryl)alkanes and alkenes are organo-bismetallic equivalents, which are synthetically important because they allow for sequential selective transformations of C–B bonds. We reviewed the synthesis...
Thu Feb 20, 2020 02:00
Molecules, Vol. 25, Pages 961: One- and Two-Electron Oxidations of β-Amyloid25-35 by Carbonate Radical Anion (CO3•−) and Peroxymonocarbonate (HCO4−): Role of Sulfur in Radical Reactions and Peptide Aggregation Molecules doi: 10.3390/molecules25040961 Authors: Antonio Francioso Alessia Baseggio Conrado Carla Blarzino Cesira Foppoli Elita Montanari Simone Dinarelli Alessandra Giorgi Luciana Mosca Mario Fontana The β-amyloid (Aβ) peptide plays a...
Thu Feb 20, 2020 02:00
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