This study aimed to assess the validity and reliability of a dish-based, semi-quantitative food frequency questionnaire (DFFQ) for epidemiological studies in Iran. The DFFQ included 142 items (84 foods and 58 ...
The biological interpretation of gene expression measurements is a challenging task. While ordination methods are routinely used to identify clusters of samples or co-expressed genes, these methods do not take...
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Publication date: Available online 24 February 2020Source: Magnetic Resonance ImagingAuthor(s): Niema M. Pahlevan, Timothy Yao, Karen Chu, Soren Cole, Thao Tran, John C. Wood, Kevin S. King
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Objectives: Immunotherapy (IO) has become standard of care (SOC) for many advanced malignancies, although identifying patients likely to benefit remains difficult. We sought to assess whether demographic factors are associated with response to IO, compared with SOC systemic therapy, using stratified meta-analysis. Methods: A systematic review of MEDLINE, PubMed, Embase, and Scopus from inception to October 2, 2018. Randomized controlled trials comparing IO to SOC in patients with advanced...
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Aim/Objectives/Background: The American College of Radiology (ACR) and the American Society for Radiation Oncology (ASTRO) have jointly developed the following practice parameter for proton beam radiation therapy. Proton radiotherapy is the application of a high-energy proton beam to a patient in a clinical setting with therapeutic intent. Proton radiotherapy may permit improved therapeutic ratios with lower doses to sensitive normal structures and greater dose to target tumor tissues. Methods:...
Objectives: We sought to evaluate sociodemographic disparities in insurance coverage among nonelderly adults with a common cancer after Affordable Care Act (ACA) implementation. Patients and Methods: In total, 109,182 patients aged 18 to 64 years diagnosed with a common cancer (lung, breast, or prostate cancer) were identified from 2010 to 2014. Multivariable logistic regressions analyzed associations between ACA implementation and uninsured rates on the basis of state approach to Medicaid...
Background: The aim of this study was to elucidate a curable subgroup among patients with non–small cell lung cancer (NSCLC) who developed postoperative recurrence. Patients and Methods: Between 1986 and 2012, among the 1408 patients who underwent complete anatomic lung resection for NSCLC at our institution, 420 developed recurrence. After excluding 14 patients with insufficient information about recurrence, 406 were included in this retrospective study. We investigated the association between...
Objectives: We studied a cohort of cancer patients that underwent curative-intent radiation within the last year of life (LYOL). Given the unexpectedly short survival, we evaluated the proportion with relapsed/refractory disease, determined causes of death, and explored whether treatment intent was associated with aggressiveness of care at the end of life. Materials and Methods: We extracted and linked claims data and radiotherapy records for patients seen at a single academic institution...
Purpose/Objective: The purpose of this study was to evaluate the role of external radiation therapy following resection of pancreatic cancer. Patients and Methods: Patients who underwent either Whipple procedure or distal pancreatectomy and treated with either chemo-radiotherapy (chemo-rad) or chemotherapy alone (R0 chemo) were enrolled in this study. The chemotherapy (chemo) was based on cisplatin and either gemcitabine or 5 FU/leukovorin. The total radiation dose was 50.4 Gy given in 1.8 Gy...
Purpose: NRG/RTOG 0848 was designed to determine whether adjuvant radiation with fluoropyrimidine sensitization improved survival following gemcitabine-based adjuvant chemotherapy for patients with resected pancreatic head adenocarcinoma. In step 1 of this protocol, patients were randomized to adjuvant gemcitabine versus the combination of gemcitabine and erlotinib. This manuscript reports the final analysis of these step 1 data. Methods: Eligibility—within 10 weeks of curative intent pancreaticoduodenectomy...
Objective: Chemotherapy has been proposed as an adjunct to primary local therapy in esthesioneuroblastoma (ENB)/olfactory neuroblastoma (ON), but its role has not been precisely defined. Here, we evaluated its role in ENB treatment. Materials and Methods: The Surveillance Epidemiology and End Results (SEER) database was queried for ENB/ON (International Classification of Diseases-3 9522). Cases met criteria for inclusion if they were unique, had a primary location in the nasal cavity, and...
Objective: To investigate the clinical outcomes and failure patterns of patients with unresectable cholangiocarcinoma (CC) who had been treated with proton beam therapy (PBT). Methods: The authors retrospectively examined 30 patients with unresectable CC who had undergone PBT between November 2015 and December 2017. Survival curves were plotted with the Kaplan-Meier method. Independent predictors of survival were identified by multivariate Cox proportional hazard regression analyses. Complications...
The understanding of localized radiation therapy’s immunostimulatory properties combined with its well-known effects on the cell cycle and insights into the immunomodulation mechanisms that occur at the molecular and cellular levels has changed our traditional view of the anticancer effects of ionizing radiation. The potential interactions between the tumor’s immune system and radiation therapy have revealed that local radiation has the ability to induce systemic antitumor responses in patients with...
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Follicular lymphoma is an indolent non-Hodgkin lymphoma that is most commonly diagnosed in elderly individuals. The majority of patients with follicular lymphoma present with advanced disease. Despite the rece...
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In this study, using new approach (laser diffraction + biological dyes), we have demonstrated the decrease of cells viability in vitro in the deuterated growth medium, whereas in the deuterium-depleted medium, there was an increase of cell viability. We have also found that not all dyes are equally sensitive to the D/H ratios in the culture medium (system) as well as to the different cell types (cancer vs normal cells).
Among agricultural soil amendment that can enhance crop productivity and soil sustainability is biochar. Hence, two-year field experiments were conducted on a sandy loam Alfisol at Owo, southwest Nigeria, to evaluate the effects of biochar produced from hardwood on soil physical and chemical characteristics, erosion potential, and cocoyam (Xanthosoma sagittifolium (L.) Schott) yield. The study was a 2 × 4 factorial experiment with two years (2017 and 2018) and four biochar levels (0 (control), 10,...
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Publication date: February 2020Source: Journal of Allergy and Clinical Immunology, Volume 145, Issue 2, SupplementAuthor(s): Carole Le Coz, Brian Nolan, Piyush Pillarisetti, Caroline Khanna, David Nguyen, Titus Boggon, Sarah Nicholas, James Verbsky, Joud Hajjar, Gregory Poon, Ivan Chinn, Alexander Marson, Neil Romberg
Publication date: February 2020Source: Journal of Allergy and Clinical Immunology, Volume 145, Issue 2, SupplementAuthor(s):
Publication date: February 2020Source: Journal of Allergy and Clinical Immunology, Volume 145, Issue 2, SupplementAuthor(s):
Publication date: February 2020Source: Journal of Allergy and Clinical Immunology, Volume 145, Issue 2, SupplementAuthor(s): Ninabahen Dave, Jenyfeer Blanco, Jessica Perkins
Publication date: February 2020Source: Journal of Allergy and Clinical Immunology, Volume 145, Issue 2, SupplementAuthor(s): Kristine Vanijcharoenkarn, William Sharp, Brian Vickery
Publication date: February 2020Source: Journal of Allergy and Clinical Immunology, Volume 145, Issue 2, SupplementAuthor(s): Nam Sze Cheng, Janita Pak Chun Chau, Ellis Kam Lun Hon, Chung Mo Chow, Kai Chow Choi, Suzanne Hoi Shan Lo, Ting Fan Leung
Publication date: February 2020Source: Journal of Allergy and Clinical Immunology, Volume 145, Issue 2, SupplementAuthor(s): Subhashini Srivatsan
Publication date: February 2020Source: Journal of Allergy and Clinical Immunology, Volume 145, Issue 2, SupplementAuthor(s): Moumita Bhowmik, Moumita Biswas Sarkar, Gaurab Sircar, Swati Gupta Bhattacharya
Publication date: February 2020Source: Journal of Allergy and Clinical Immunology, Volume 145, Issue 2, SupplementAuthor(s): Anne Lesage, Brigitte Loenders, Jochen Knolle
Publication date: February 2020Source: Journal of Allergy and Clinical Immunology, Volume 145, Issue 2, SupplementAuthor(s): Avery DeVries, Kei Fujimura, Debra Stern, Anne Wright, Marilyn Halonen, Susan Lynch, Donata Vercelli
Publication date: February 2020Source: Journal of Allergy and Clinical Immunology, Volume 145, Issue 2, SupplementAuthor(s): Anita Roach, Christopher Warren, Nurry Hong, Ruchi Gupta, Thomas Casale
Publication date: February 2020Source: Journal of Allergy and Clinical Immunology, Volume 145, Issue 2, SupplementAuthor(s): David Dworaczyk, Allen Hunt
Publication date: February 2020Source: Journal of Allergy and Clinical Immunology, Volume 145, Issue 2, SupplementAuthor(s): Vaidehi Bhatt, Vince Wu, Kristiina Frechette, Tarin Moni, Wardha Wardha
Publication date: February 2020Source: Journal of Allergy and Clinical Immunology, Volume 145, Issue 2, SupplementAuthor(s): Audrey Dunn-Galvin, Kuang-Chih Hsiao, Christine Axelrad, Sigrid Pitkin
Publication date: February 2020Source: Journal of Allergy and Clinical Immunology, Volume 145, Issue 2, SupplementAuthor(s): Neelam Phadke, Anna Wolfson, Mark Matza, Eli Miloslavsky, Ohn Chow, Lacey Robinson, Aidan Long, Kimberly Blumenthal, Aleena Banerji
Publication date: February 2020Source: Journal of Allergy and Clinical Immunology, Volume 145, Issue 2, SupplementAuthor(s): Hong Ji, Xue Zhang, Jocelyn Biagini Myers, Xiaoting Chen, Matthew Weirauch, Theresa Guilbert, Gurjit Khurana Hershey
Publication date: February 2020Source: Journal of Allergy and Clinical Immunology, Volume 145, Issue 2, SupplementAuthor(s): Wei-Tian Zhang, Guang-Yi Ba, Ru Tang, Ming-Xian Li, Hai Lin
Publication date: February 2020Source: Journal of Allergy and Clinical Immunology, Volume 145, Issue 2, SupplementAuthor(s): David Coleman, Cosby Stone, Wei-Qi Wei, Elizabeth Phillips
Publication date: February 2020Source: Journal of Allergy and Clinical Immunology, Volume 145, Issue 2, SupplementAuthor(s): Hannah Brown, Bobby Tajudeen, Hannah Kuhar, Pete Batra, Paolo Gattuso, Mahboobeh Mahdavinia
Publication date: February 2020Source: Journal of Allergy and Clinical Immunology, Volume 145, Issue 2, SupplementAuthor(s): Pooja Jhaveri, Kristin Lambert, Faoud Ishmael, Punit Jhaveri, Chandran Alexander, Steve Hicks
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