Antibiotics, Vol. 9, Pages 98: Effective Photodynamic Inactivation of 26 Escherichia coli Strains with Different Antibiotic Susceptibility Profiles: a Planktonic and Biofilm StudyAntibiotics doi: 10.3390/antibiotics9030098Authors:Òscar GulíasGiselle McKenzieMiquel BayóMontserrat AgutSanti NonellThe emergence of multidrug-resistant bacteria is a growing problem and alternative therapies are being sought to effectively address this issue. The aim of this study is to assess a range of Escherichia coli...
Tue Feb 25, 2020 02:00
Antioxidants, Vol. 9, Pages 193: Potential Applications of NRF2 Modulators in Cancer Therapy Antioxidants doi: 10.3390/antiox9030193 Authors: Panieri Buha Telkoparan-Akillilar Cevik Kouretas Veskoukis Skaperda Tsatsakis Wallace Suzen Saso The nuclear factor erythroid 2-related factor 2 (NRF2)–Kelch-like ECH-associated protein 1 (KEAP1) regulatory pathway plays an essential role in protecting cells and tissues from oxidative, electrophilic,...
Tue Feb 25, 2020 02:00
Antioxidants, Vol. 9, Pages 192: Anti–Inflammatory and Antioxidant Properties of the Ethanol Extract of Clerodendrum Cyrtophyllum Turcz in Copper Sulfate-Induced Inflammation in Zebrafish Antioxidants doi: 10.3390/antiox9030192 Authors: Nguyen Le Kim The Nguyen Cornet Lambert Kestemont Oxidative stress and inflammation are commonly present in many chronic diseases. These responses are closely related to pathophysiological processes. The inflammatory process...
Tue Feb 25, 2020 02:00
Antioxidants, Vol. 9, Pages 194: Emodin Scavenging of Superoxide Radical Includes π–π Interaction. X-Ray Crystal Structure, Hydrodynamic Voltammetry and Theoretical Studies Antioxidants doi: 10.3390/antiox9030194 Authors: Rossi Wen Caruso Belli The naturally occurring anthraquinone emodin is found in many plants that have been part of traditional Chinese medicine (TCM) for thousands of years. Recent pharmacological studies suggest that emodin might be a valuable therapeutic...
Tue Feb 25, 2020 02:00
Antioxidants, Vol. 9, Pages 191: Utilizing Iron for Targeted Lipid Peroxidation as Anticancer Option of Integrative Biomedicine: A Short Review of Nanosystems Containing Iron Antioxidants doi: 10.3390/antiox9030191 Authors: Jaganjac Borovic Sunjic Zarkovic Traditional concepts of life sciences consider oxidative stress as a fundamental process of aging and various diseases including cancer, whereas traditional medicine recommends dietary intake of iron to support physiological...
Tue Feb 25, 2020 02:00
Antioxidants, Vol. 9, Pages 188: Resveratrol in Autism Spectrum Disorders: Behavioral and Molecular Effects Antioxidants doi: 10.3390/antiox9030188 Authors: Malaguarnera Khan Cauli Resveratrol (RSV) is a polyphenolic stillbenoid with significant anti-oxidative and anti-inflammatory properties recently tested in animal models of several neurological diseases. Altered immune alteration and oxidative stress have also been found in patients with autism spectrum disorders (ASD),...
Tue Feb 25, 2020 02:00
Antioxidants, Vol. 9, Pages 190: Comparative Study on Phytochemical Profiles and Antioxidant Capacities of Chestnuts Produced in Different Geographic Area in China Antioxidants doi: 10.3390/antiox9030190 Authors: Ziyun Xu Maninder Meenu Pengyu Chen Baojun Xu This study aimed to systematically assess the phenolic profiles and antioxidant capacities of 21 chestnut samples collected from six geographical areas of China. All these samples exhibit significant differences (p <...
Tue Feb 25, 2020 02:00
Antioxidants, Vol. 9, Pages 189: Computational Study of Ortho-Substituent Effects on Antioxidant Activities of Phenolic Dendritic Antioxidants Antioxidants doi: 10.3390/antiox9030189 Authors: Lee Sharma Semenya Anamoah Chapman Barone Antioxidants are an important component of our ability to combat free radicals—an excess of which leads to oxidative stress, which is related to aging and numerous human diseases. Oxidative damage also shortens the shelf-life...
Tue Feb 25, 2020 02:00
Arts, Vol. 9, Pages 29: Filling History, Consolidating the Origins. The First Female Architects of the Barcelona School of Architecture (1964–1975) Arts doi: 10.3390/arts9010029 Authors: Muxí Arias Laurino After Francisco Franco’s death, the process of democratisation of public institutions was a key factor in the evolution of the architectural profession in Spain. The approval of the creation of neighbourhood associations, the first municipal governments, and the modernisation...
Tue Feb 25, 2020 02:00
Arts, Vol. 9, Pages 28: Art Criticism and the State of Feminist Art Criticism Arts doi: 10.3390/arts9010028 Authors: Deepwell This essay is in four parts. The first offers a critique of James Elkins and Michael Newman’s book The State of Art Criticism (Routledge, 2008) for what it tells us about art criticism in academia and journalism and feminism; the second considers how a gendered analysis measures the “state” of art and art criticism as a feminist...
Tue Feb 25, 2020 02:00
Arts, Vol. 9, Pages 27: Staging Proto-Zionism. Jewish Quarter of Zemun, Serbia: Historical Evidence, Structure, Meaning Arts doi: 10.3390/arts9010027 Authors: Marinković Zemun is an old Central European town on the right bank of the Danube River, today one of the boroughs of Belgrade, the capital of Serbia. There has been a small Jewish community in Zemun dating back to the mid-18th century. Some of the Jews who lived in Zemun in the 19th century contributed to the emergence of Zionism....
Tue Feb 25, 2020 02:00
Atmosphere, Vol. 11, Pages 224: Assessing Peak-to-Mean Ratios of Odour Intensity in the Atmosphere Near Swine Operations Atmosphere doi: 10.3390/atmos11030224 Authors: Zhang Zhou Odour in the atmosphere is usually characterized by an intermittent time series of high peaks and periods of low (or zero) concentrations. The peak-to-mean ratio (PMR) is commonly used to estimate short-term peaks from long-term averages to assess the odour impact. The objective of this study was to quantify...
Tue Feb 25, 2020 02:00
Atmosphere, Vol. 11, Pages 223: Relationships between Exposure to Bioaerosols, Moldy Surface and Symptoms in French Mold-Damaged Homes Atmosphere doi: 10.3390/atmos11030223 Authors: Antoine Delanoë Natacha Heutte Stéphanie Gente Virginie Séguin David Garon Air quality in homes is a major concern in Europe, where people spend most of their time indoors. According to the World Health Organization, numerous houses are subject to dampness that can lead to mold growth, with associated...
Tue Feb 25, 2020 02:00
Atmosphere, Vol. 11, Pages 222: Model Inter-Comparison for PM2.5 Components over urban Areas in Japan in the J-STREAM Framework Atmosphere doi: 10.3390/atmos11030222 Authors: Yamaji Chatani Itahashi Saito Takigawa Morikawa Kanda Miya Komatsu Sakurai Morino Kitayama Nagashima Shimadera Uranishi Fujiwara Hashimoto Sudo Misaki Hayami A model inter-comparison of secondary pollutant simulations over urban areas in...
Tue Feb 25, 2020 02:00
Beverages, Vol. 6, Pages 13: Functional Efficacy of Probiotic Lactobacillus sanfranciscensis in Apple, Orange and Tomato Juices with Special Reference to Storage Stability and In Vitro Gastrointestinal Survival Beverages doi: 10.3390/beverages6010013 Authors: Wenjie Zhu Fengzhi Lyu Nenad Naumovski Said Ajlouni Chaminda Senaka Ranadheera There is an increasing demand for non-dairy probiotic carriers such as fruit and vegetable juices. Probiotic Lactobacillus sanfranciscensis...
Tue Feb 25, 2020 02:00
Beverages, Vol. 6, Pages 12: An approach of the Madeira Wine Chemistry Beverages doi: 10.3390/beverages6010012 Authors: Rosa Perestrelo Catarina Silva Carolina Gonçalves Mariangie Castillo José S. Câmara Madeira wine is a fortified Portuguese wine, which has a crucial impact on the Madeira Island economy. The particular properties of Madeira wine result from the unique and specific winemaking and ageing processes that promote the occurrence of chemical reactions among acids,...
Tue Feb 25, 2020 02:00
Biology, Vol. 9, Pages 41: Comparative Ergot Alkaloid Elaboration by Selected Plectenchymatic Mycelia of Claviceps purpurea through Sequential Cycles of Axenic Culture and Plant Parasitism Biology doi: 10.3390/biology9030041 Authors: Mantle Ergot alkaloids have an established place in plant pathology and toxicology. As pharmaceuticals, their sourcing is via natural or managed agricultural occurrence of sclerotia of Claviceps purpurea (Fr.) Tul. or through industrial fermentation processes...
Tue Feb 25, 2020 02:00
Biology, Vol. 9, Pages 40: Effects of Fish Predators on the Mass-Related Energetics of a Keystone Freshwater Crustacean Biology doi: 10.3390/biology9030040 Authors: Douglas S. Glazier Jonathan J. Borrelli Casandra L. Hoffman Little is known about how predators or their cues affect the acquisition and allocation of energy throughout the ontogeny of prey organisms. To address this question, we have been comparing the ontogenetic body-mass scaling of various traits related to energy...
Tue Feb 25, 2020 02:00
Biomedicines, Vol. 8, Pages 43: Comparative Study of the Effects of GLP1 Analog and SGLT2 Inhibitor against Diabetic Cardiomyopathy in Type 2 Diabetic Rats: Possible Underlying Mechanisms Biomedicines doi: 10.3390/biomedicines8030043 Authors: Hussein Eid Taha Elshazli Bedir Lashin The present study investigated the possible cardioprotective effects of GLP1 and SGLT2i against diabetic cardiomyopathy (DCM) in type 2 diabetic rats and the possible underlying mechanisms....
Tue Feb 25, 2020 02:00
Biomedicines, Vol. 8, Pages 42: A Comparative Study of The Effects of Anticoagulants on Pure Platelet-Rich Plasma Quality and Potency Biomedicines doi: 10.3390/biomedicines8030042 Authors: Aizawa Kawabata Sato Masuki Watanabe Tsujino Isobe Nakamura Nakata Kawase It is generally accepted that citrate or the A-form of acid-citrate-dextrose (ACD-A) are suitable for preparing platelet-rich plasma (PRP) for regenerative therapy. However, this is based...
Tue Feb 25, 2020 02:00
Biomolecules, Vol. 10, Pages 352: Traditional Uses, Bioactive Chemical Constituents, and Pharmacological and Toxicological Activities of Glycyrrhiza glabra L. (Fabaceae) Biomolecules doi: 10.3390/biom10030352 Authors: El-Saber Batiha Magdy Beshbishy El-Mleeh Abdel-Daim Prasad Devkota Traditional herbal remedies have been attracting attention as prospective alternative resources of therapy for diverse diseases across many nations. In recent decades, medicinal plants have...
Tue Feb 25, 2020 02:00
Biomolecules, Vol. 10, Pages 351: Bacterial Enhancer Binding Proteins—AAA+ Proteins in Transcription Activation Biomolecules doi: 10.3390/biom10030351 Authors: Gao Danson Ye Jovanovic Buck Zhang Bacterial enhancer-binding proteins (bEBPs) are specialised transcriptional activators. bEBPs are hexameric AAA+ ATPases and use ATPase activities to remodel RNA polymerase (RNAP) complexes that contain the major variant sigma factor, σ54 to convert the initial...
Tue Feb 25, 2020 02:00
Biomolecules, Vol. 10, Pages 350: Current and Novel Therapies Against Helminthic Infections: The Potential of Antioxidants Combined with Drugs Biomolecules doi: 10.3390/biom10030350 Authors: Vale Gouveia Gärtner Infections caused by Schistosoma haematobium and Opisthorchis viverrini are classified as Group 1 biological carcinogen and it has been postulated that parasites produce oxysterol and estrogen-like metabolites that might be considered as initiators of infection-associated...
Tue Feb 25, 2020 02:00
Biosensors, Vol. 10, Pages 15: Food Sensing: Detection of Bacillus cereus Spores in Dairy Products Biosensors doi: 10.3390/bios10030015 Authors: Jasmina Vidic Carole Chaix Marisa Manzano Marc Heyndrickx Milk is a source of essential nutrients for infants and adults, and its production has increased worldwide over the past years. Despite developments in the dairy industry, premature spoilage of milk due to the contamination by Bacillus cereus continues to be a problem and causes...
Tue Feb 25, 2020 02:00
Brain Sciences, Vol. 10, Pages 129: Neuropeptides’ Hypothalamic Regulation of Sleep Control in Children Affected by Functional Non-Retentive Fecal Incontinence Brain Sciences doi: 10.3390/brainsci10030129 Authors: Vincenzo Monda Marco Carotenuto Francesco Precenzano Diego Iacono Antonietta Messina Monica Salerno Francesco Sessa Valentina Lanzara Giovanni Messina Giuseppe Quatrosi Rosaria Nardello Francesca Felicia Operto Claudia Santoro Fiorenzo Moscatelli...
Tue Feb 25, 2020 02:00
Cancers, Vol. 12, Pages 531: Reduced SKP1 Expression Induces Chromosome Instability through Aberrant Cyclin E1 Protein Turnover Cancers doi: 10.3390/cancers12030531 Authors: Thompson Baergen Lichtensztejn McManus Chromosome instability (CIN), or progressive changes in chromosome numbers, is an enabling feature of many cancers; however, the mechanisms giving rise to CIN remain poorly understood. To expand our mechanistic understanding of the molecular determinants of CIN...
Tue Feb 25, 2020 02:00
Cancers, Vol. 12, Pages 532: Role of Akt Activation in PARP Inhibitor Resistance in Cancer Cancers doi: 10.3390/cancers12030532 Authors: Gallyas Jr Sumegi Szabo Poly(ADP-ribose) polymerase (PARP) inhibitors have recently been introduced in the therapy of several types of cancers not responding to conventional treatments. However, de novo and acquired PARP inhibitor resistance is a significant limiting factor in the clinical therapy, and the underlying mechanisms are not fully...
Tue Feb 25, 2020 02:00
Cancers, Vol. 12, Pages 530: The Disturbed Iron Phenotype of Tumor Cells and Macrophages in Renal Cell Carcinoma Influences Tumor Growth Cancers doi: 10.3390/cancers12030530 Authors: Schnetz Meier Rehwald Mertens Urbschat Tomat Akam Baer Roos Brüne Jung Accumulating evidence suggests that iron homeostasis is disturbed in tumors. We aimed at clarifying the distribution of iron in renal cell carcinoma (RCC). Considering the pivotal role of macrophages...
Tue Feb 25, 2020 02:00
Cancers, Vol. 12, Pages 528: The Role of p53-Mediated Signaling in the Therapeutic Response of Colorectal Cancer to 9F, a Spermine-Modified Naphthalene Diimide Derivative Cancers doi: 10.3390/cancers12030528 Authors: Gao Ge Wang Xu Feng Li Wang Wang Dai Xie Colorectal cancer (CRC) is one of the most prevalent cancers due to its frequency and high rate of mortality. Polyamine-vectorized anticancer drugs possess multiple biological properties. Of these...
Tue Feb 25, 2020 02:00
Cancers, Vol. 12, Pages 529: Highly Expressed miR-375 is not an Intracellular Oncogene in Merkel Cell Polyomavirus-Associated Merkel Cell Carcinoma Cancers doi: 10.3390/cancers12030529 Authors: Fan Zebisch Horny Schrama Becker miR-375 is a highly abundant miRNA in Merkel cell carcinoma (MCC). In other cancers, it acts as either a tumor suppressor or oncogene. While free-circulating miR-375 serves as a surrogate marker for tumor burden in patients with advanced MCC, its...
Tue Feb 25, 2020 02:00
Cancers, Vol. 12, Pages 526: Efficacy of Crizotinib, Ceritinib, and Alectinib in ALK-Positive Non-Small Cell Lung Cancer Treatment: A Meta-Analysis of Clinical Trials Cancers doi: 10.3390/cancers12030526 Authors: Hoang Myung Pham Park This study aimed to evaluate the efficacy of anaplastic lymphoma kinase (ALK)-inhibitors in the treatment of ALK-positive non-small cell lung cancer (NSCLC) by using a meta-analysis of clinical trials. We searched PubMed, EMBASE, Cochrane Library,...
Tue Feb 25, 2020 02:00
Cancers, Vol. 12, Pages 527: Animal Models in Microbeam Radiation Therapy: A Scoping Review Cancers doi: 10.3390/cancers12030527 Authors: Fernandez-Palomo Fazzari Trappetti Smyth Janka Laissue Djonov Background: Microbeam Radiation Therapy (MRT) is an innovative approach in radiation oncology where a collimator subdivides the homogeneous radiation field into an array of co-planar, high-dose beams which are tens of micrometres wide and separated by a few hundred...
Tue Feb 25, 2020 02:00
Cancers, Vol. 12, Pages 525: Cannabinoids and Hormone Receptor-Positive Breast Cancer Treatment Cancers doi: 10.3390/cancers12030525 Authors: Dobovišek Krstanović Borštnar Debeljak Breast cancer (BC) is the most common cancer in women worldwide. Approximately 70–80% of BCs express estrogen receptors (ER), which predict the response to endocrine therapy (ET), and are therefore hormone receptor-positive (HR+). Endogenous cannabinoids together with cannabinoid receptor...
Tue Feb 25, 2020 02:00
Cells, Vol. 9, Pages 534: Functions of Vertebrate Ferlins Cells doi: 10.3390/cells9030534 Authors: Bulankina Thoms Ferlins are multiple-C2-domain proteins involved in Ca2+-triggered membrane dynamics within the secretory, endocytic and lysosomal pathways. In bony vertebrates there are six ferlin genes encoding, in humans, dysferlin, otoferlin, myoferlin, Fer1L5 and 6 and the long noncoding RNA Fer1L4. Mutations in DYSF (dysferlin) can cause a range of muscle diseases with various...
Tue Feb 25, 2020 02:00
Cells, Vol. 9, Pages 535: Glaucoma: A Degenerative Optic Neuropathy Related to Neuroinflammation? Cells doi: 10.3390/cells9030535 Authors: Mélik Parsadaniantz Réaux-le Goazigo Sapienza Habas Baudouin Glaucoma is one of the leading causes of irreversible blindness in the world and remains a major public health problem. To date, incomplete knowledge of this disease’s pathophysiology has resulted in current therapies (pharmaceutical or surgical) unfortunately...
Tue Feb 25, 2020 02:00
Cells, Vol. 9, Pages 533: Circumventing AKT-Associated Radioresistance in Oral Cancer by Novel Nanoparticle-Encapsulated Capivasertib Cells doi: 10.3390/cells9030533 Authors: Lang Lam Chen Jensen Duncan Kong Kurago Shay Teng Background: Development of radioresistance in oral squamous cell carcinoma (OSCC) remains a significant problem in cancer treatment, contributing to the lack of improvement in survival trends in recent decades. Effective strategies...
Tue Feb 25, 2020 02:00
Cells, Vol. 9, Pages 530: Defocused Images Change Multineuronal Firing Patterns in the Mouse Retina Cells doi: 10.3390/cells9030530 Authors: Banerjee Wang So Pan Myopia is a major public health problem, affecting one third of the population over 12 years old in the United States and more than 80% of people in Hong Kong. Myopia is attributable to elongation of the eyeball in response to defocused images that alter eye growth and refraction. It is known that the retina can...
Tue Feb 25, 2020 02:00
Cells, Vol. 9, Pages 531: Memory CD4+ T Cells in Immunity and Autoimmune Diseases Cells doi: 10.3390/cells9030531 Authors: Raphael Joern Forsthuber CD4+ T helper (Th) cells play central roles in immunity in health and disease. While much is known about the effector function of Th cells in combating pathogens and promoting autoimmune diseases, the roles and biology of memory CD4+ Th cells are complex and less well understood. In human autoimmune diseases such as multiple sclerosis...
Tue Feb 25, 2020 02:00
Cells, Vol. 9, Pages 532: miRNA-Based Rapid Differentiation of Purified Neurons from hPSCs Advancestowards Quick Screening for Neuronal Disease Phenotypes In Vitro Cells doi: 10.3390/cells9030532 Authors: Ishikawa Aoyama Shibata Sone Miyoshi Watanabe Nakamura Morota Uchino Yoo Okano Obtaining differentiated cells with high physiological functions by an efficient, but simple and rapid differentiation method is crucial for modeling neuronal diseases...
Tue Feb 25, 2020 02:00
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