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Τετάρτη 26 Φεβρουαρίου 2020


Clinical outcome of post-chemotherapy retroperitoneal lymph node dissection in metastatic nonseminomatous germ cell tumour: A systematic review
Publication date: Available online 26 February 2020Source: European Journal of Surgical OncologyAuthor(s): Rianne Haarsma, Joost M. Blok, Kim van Putten, Richard P. Meijer
European Journal of Surgical Oncology (EJSO)
Wed Feb 26, 2020 15:05
Psychosocial well-being at time of diagnosis of breast cancer affects the decision whether or not to undergo breast reconstruction
Publication date: Available online 25 February 2020Source: European Journal of Surgical OncologyAuthor(s): Renée Miseré, Sander Schop, Esther Heuts, Andrzej Piatkowski de Grzymala, René Hulst van der
European Journal of Surgical Oncology (EJSO)
Wed Feb 26, 2020 15:05
Antioxidant, Antiproliferative and Apoptosis-Inducing Efficacy of Fractions from Cassia fistula L. Leaves.
Related ArticlesAntioxidant, Antiproliferative and Apoptosis-Inducing Efficacy of Fractions from Cassia fistula L. Leaves. Antioxidants (Basel). 2020 Feb 20;9(2): Authors: Kaur S, Kumar A, Thakur S, Kumar K, Sharma R, Sharma A, Singh P, Sharma U, Kumar S, Landi M, Brestič M, Kaur S Abstract : Cassia fistula L. is a highly admirable traditional medicinal plant used for the treatment of various diseases and disorders. The present study was performed to...
pubmed: cell cycle arrest
Wed Feb 26, 2020 15:02
Buxus alkaloid compound destabilizes mutant p53 through inhibition of the HSF1 chaperone axis.
Related ArticlesBuxus alkaloid compound destabilizes mutant p53 through inhibition of the HSF1 chaperone axis. Phytomedicine. 2020 Feb 08;68:153187 Authors: Wang YL, Wu W, Su YN, Ai ZP, Mou HC, Wan LS, Luo Y, Qiu MH, Zhang JH Abstract BACKGROUND: P53 is the most frequently mutated gene in most tumour types, and the mutant p53 protein accumulates at high levels in tumours to promote tumour development and progression. Thus, targeting mutant p53 for degradation...
pubmed: cell cycle arrest
Wed Feb 26, 2020 15:02
Ziyuglycoside II exerts antiproliferative and antimetastasis effects on hepatocellular carcinoma cells.
Related ArticlesZiyuglycoside II exerts antiproliferative and antimetastasis effects on hepatocellular carcinoma cells. Anticancer Drugs. 2020 Feb 22;: Authors: Liao W, Fan L, Zheng Z, Liu H, Deng H, Li M, Liu F, Yang A Abstract Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide. Phytochemicals are important candidates for developing anticancer agents. Ziyuglycoside II is a major active compound of Sanguisorba officinalis,...
pubmed: cell cycle arrest
Wed Feb 26, 2020 15:02
Down-regulation of lncRNA BLACAT1 inhibits ovarian cancer progression by suppressing the Wnt/β-catenin signaling pathway via regulating miR-519d-3p.
Related ArticlesDown-regulation of lncRNA BLACAT1 inhibits ovarian cancer progression by suppressing the Wnt/β-catenin signaling pathway via regulating miR-519d-3p. Mol Cell Biochem. 2020 Feb 24;: Authors: Yang H, Qi Y, Wang XL, Gu JJ, Shi TM Abstract Ovarian cancer has the highest mortality in gynecologic malignancies. LncRNA BLACAT1 serves crucial functions in various cancers, but its role in ovarian cancer has not been investigated. In this article,...
pubmed: cell cycle arrest
Wed Feb 26, 2020 13:00
MARCH5 requires MTCH2 to coordinate proteasomal turnover of the MCL1:NOXA complex.
Related ArticlesMARCH5 requires MTCH2 to coordinate proteasomal turnover of the MCL1:NOXA complex. Cell Death Differ. 2020 Feb 24;: Authors: Djajawi TM, Liu L, Gong JN, Huang AS, Luo MJ, Xu Z, Okamoto T, Call MJ, Huang DCS, van Delft MF Abstract MCL1, a BCL2 relative, is critical for the survival of many cells. Its turnover is often tightly controlled through both ubiquitin-dependent and -independent mechanisms of proteasomal degradation. Several cell...
pubmed: cell cycle arrest
Wed Feb 26, 2020 13:00
Suppressing STAT5 signaling affects osteosarcoma growth and stemness.
Related ArticlesSuppressing STAT5 signaling affects osteosarcoma growth and stemness. Cell Death Dis. 2020 Feb 24;11(2):149 Authors: Subramaniam D, Angulo P, Ponnurangam S, Dandawate P, Ramamoorthy P, Srinivasan P, Iwakuma T, Weir SJ, Chastain K, Anant S Abstract Osteosarcoma (OS) is the most common primary bone tumor that primarily affects children and adolescents. Studies suggested that dysregulation JAK/STAT signaling promotes the development of OS....
pubmed: cell cycle arrest
Wed Feb 26, 2020 13:00
Working on Genomic Stability: From the S-Phase to Mitosis.
Related ArticlesWorking on Genomic Stability: From the S-Phase to Mitosis. Genes (Basel). 2020 Feb 20;11(2): Authors: Ovejero S, Bueno A, Sacristán MP Abstract Fidelity in chromosome duplication and segregation is indispensable for maintaining genomic stability and the perpetuation of life. Challenges to genome integrity jeopardize cell survival and are at the root of different types of pathologies, such as cancer. The following three main sources of...
pubmed: cell cycle arrest
Wed Feb 26, 2020 13:00
Hexane Insoluble Fraction from Purple Rice Extract Retards Carcinogenesis and Castration-Resistant Cancer Growth of Prostate Through Suppression of Androgen Receptor Mediated Cell Proliferation and Metabolism.
Related ArticlesHexane Insoluble Fraction from Purple Rice Extract Retards Carcinogenesis and Castration-Resistant Cancer Growth of Prostate Through Suppression of Androgen Receptor Mediated Cell Proliferation and Metabolism. Nutrients. 2020 Feb 20;12(2): Authors: Yeewa R, Naiki-Ito A, Naiki T, Kato H, Suzuki S, Chewonarin T, Takahashi S Abstract Prostate cancer and castration-resistant prostate cancer (CRPC) remain major health challenges in men. In...
pubmed: cell cycle arrest
Wed Feb 26, 2020 13:00
The Effects of 5,6,7,8,3',4'-Hexamethoxyflavone on Apoptosis of Cultured Human Choriocarcinoma Trophoblast Cells.
Related ArticlesThe Effects of 5,6,7,8,3',4'-Hexamethoxyflavone on Apoptosis of Cultured Human Choriocarcinoma Trophoblast Cells. Molecules. 2020 Feb 20;25(4): Authors: Zhang M, Zhang R, Liu J, Wang H, Wang Z, Liu J, Shan Y, Yu H Abstract 5,6,7,8,3,4'-Hexamethoxyflavone, also called nobiletin (NOB), widely found in the citrus peel, is one of the main byproducts in citrus processing. NOB is considered safe, but its safety for women during pregnancy is...
pubmed: cell cycle arrest
Wed Feb 26, 2020 13:00
Transmembrane Channel-Like 5 (TMC5) promotes prostate cancer cell proliferation through cell cycle regulation.
Related ArticlesTransmembrane Channel-Like 5 (TMC5) promotes prostate cancer cell proliferation through cell cycle regulation. Biochimie. 2019 Oct;165:115-122 Authors: Zhang W, Wang S, Zhang X, Liu K, Song J, Leng X, Luo R, Ran L Abstract BACKGROUND: In this study, we aimed to investigate the biological functions of Transmembrane Channel-Like 5 (TMC5) by bioinformatics and molecular biology methods in prostate cancer (PCa). METHODS: We assessed...
pubmed: cell cycle arrest
Wed Feb 26, 2020 13:00
Electroporated recombinant proteins as tools for in vivo functional complementation, imaging and chemical biology.
Related ArticlesElectroporated recombinant proteins as tools for in vivo functional complementation, imaging and chemical biology. Elife. 2019 07 16;8: Authors: Alex A, Piano V, Polley S, Stuiver M, Voss S, Ciossani G, Overlack K, Voss B, Wohlgemuth S, Petrovic A, Wu Y, Selenko P, Musacchio A, Maffini S Abstract Delivery of native or chemically modified recombinant proteins into mammalian cells shows promise for functional investigations and various...
pubmed: cell cycle arrest
Wed Feb 26, 2020 13:00
Epigenetic modifiers 5-aza-2'-deoxycytidine and valproic acid differentially change viability, DNA damage and gene expression in metastatic and non-metastatic colon cancer cell lines.
Related ArticlesEpigenetic modifiers 5-aza-2'-deoxycytidine and valproic acid differentially change viability, DNA damage and gene expression in metastatic and non-metastatic colon cancer cell lines. Acta Biochim Pol. 2019 Jul 09;66(3):355-360 Authors: Ghecham A, Senator A, Pawlowska E, Bouafia W, Błasiak J Abstract DNA methylation and histone modifications are major components of cellular epigenetic pattern determining gene expression. Cancer cells...
pubmed: cell cycle arrest
Wed Feb 26, 2020 13:00
Catalpol inhibits cell proliferation, invasion and migration through regulating miR-22-3p/MTA3 signalling in hepatocellular carcinoma.
Related ArticlesCatalpol inhibits cell proliferation, invasion and migration through regulating miR-22-3p/MTA3 signalling in hepatocellular carcinoma. Exp Mol Pathol. 2019 08;109:51-60 Authors: Zhao L, Wang Y, Liu Q Abstract Hepatocellular carcinoma (HCC) is the most common type of liver malignancy with high rates of recurrence and mortality worldwide. Unfortunately, effective strategies for the management of HCC are still unsatisfactory. The aim of...
pubmed: cell cycle arrest
Wed Feb 26, 2020 13:00
Bone morphogenetic protein 4 regulates immortalized chicken preadipocyte proliferation by promoting G1/S cell cycle progression.
Related ArticlesBone morphogenetic protein 4 regulates immortalized chicken preadipocyte proliferation by promoting G1/S cell cycle progression. FEBS Open Bio. 2019 06;9(6):1109-1118 Authors: Chen H, Liu C, Chen C, Su Z, Shu J, Zhang M, Li H, Cheng B Abstract Bone morphogenetic protein 4 (BMP4) has been reported to regulate adipose development, but its role in preadipocyte proliferation has not been explored in vitro. Here, we investigated the effect...
pubmed: cell cycle arrest
Wed Feb 26, 2020 13:00
Hemithioindigos for Cellular Photopharmacology: Desymmetrised Molecular Switch Scaffolds Enabling Design Control over the Isomer-Dependency of Potent Antimitotic Bioactivity.
Related ArticlesHemithioindigos for Cellular Photopharmacology: Desymmetrised Molecular Switch Scaffolds Enabling Design Control over the Isomer-Dependency of Potent Antimitotic Bioactivity. Chembiochem. 2019 05 15;20(10):1305-1314 Authors: Sailer A, Ermer F, Kraus Y, Lutter FH, Donau C, Bremerich M, Ahlfeld J, Thorn-Seshold O Abstract Druglike small molecules with photoswitchable bioactivity-photopharmaceuticals-allow biologists to perform studies...
pubmed: cell cycle arrest
Wed Feb 26, 2020 13:00
MiR-218-5p targets LHFPL3 to regulate proliferation, migration, and epithelial-mesenchymal transitions of human glioma cells.
Related ArticlesMiR-218-5p targets LHFPL3 to regulate proliferation, migration, and epithelial-mesenchymal transitions of human glioma cells. Biosci Rep. 2019 03 29;39(3): Authors: Li Z, Qian R, Zhang J, Shi X Abstract Glioblastoma (GBM) is a main subtype of high-grade gliomas with features in progressive brain tumor. Lipoma HMGIC fusion partner-like 3 (LHFPL3) is reported to be highly expressed in malignant glioma, but the relationship and mechanism...
pubmed: cell cycle arrest
Wed Feb 26, 2020 13:00
Astragaloside suppresses tumor necrosis factor receptor-associated factor 5 signaling pathway and alleviates neurodegenerative changes in retinal pigment epithelial cells induced by isoflurane.
Related ArticlesAstragaloside suppresses tumor necrosis factor receptor-associated factor 5 signaling pathway and alleviates neurodegenerative changes in retinal pigment epithelial cells induced by isoflurane. J Cell Biochem. 2019 01;120(1):1028-1037 Authors: Chen PJ, Shang AQ, Wang WW, Yang JP Abstract Epidemiological studies showed that isoflurane, a general anesthetic widely used in surgery including those for the children, is associated with impairment...
pubmed: cell cycle arrest
Wed Feb 26, 2020 13:00
Transcriptome mining of non-BRCA1/A2 and BRCA1/A2 familial breast cancer.
Related ArticlesTranscriptome mining of non-BRCA1/A2 and BRCA1/A2 familial breast cancer. J Cell Biochem. 2019 01;120(1):575-583 Authors: Akbari V, Kallhor M, Akbari MT Abstract About 10% of all breast cancer cases are the familial type. Mutations in two highly penetrance breast cancer susceptibility genes, BRCA1 and BRCA2, can only explain 20% to 25% of genetic susceptibility to breast cancer, and most familial breast cancer cases have intact BRCA1...
pubmed: cell cycle arrest
Wed Feb 26, 2020 13:00
The meaning of non-classical estrogen receptors and peroxisome proliferator-activated receptor for boar Leydig cell of immature testis.
Related ArticlesThe meaning of non-classical estrogen receptors and peroxisome proliferator-activated receptor for boar Leydig cell of immature testis. Acta Histochem. 2020 Feb 22;:151526 Authors: Kotula-Balak M, Duliban M, Pawlicki P, Tuz R, Bilinska B, Plachno BJ, Arent ZJ, Krakowska I, Tarasiuk K Abstract Communication in biological systems involves diverse-types of cell-cell interaction including cross-talk between receptors expressed by the target...
histochem
Wed Feb 26, 2020 15:00
An exploration of recorded otological manifestations in South African children with HIV/AIDS: A pilot study.
Related ArticlesAn exploration of recorded otological manifestations in South African children with HIV/AIDS: A pilot study. Int J Pediatr Otorhinolaryngol. 2020 Feb 18;133:109960 Authors: Khoza-Shangase K, Anastasiou J Abstract CONTEXT: The human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) is a pandemic currently presenting as one of South Africa's largest health challenges. Within the pediatric population, hearing plays a vital...
International journal of pediatric otorhinolaryngology,http://goo.gl/4YdRhz
Wed Feb 26, 2020 14:59
Is the spontaneous speech of 7-year-old cochlear implanted children as intelligible as that of their normally hearing peers?
Related ArticlesIs the spontaneous speech of 7-year-old cochlear implanted children as intelligible as that of their normally hearing peers? Int J Pediatr Otorhinolaryngol. 2020 Feb 15;133:109956 Authors: Boonen N, Kloots H, Gillis S Abstract OBJECTIVES: Studies on speech intelligibility usually focus on either individual words, sentences or longer sequences of speech. Since these different kinds of speech samples can be judged using different methodologies,...
International journal of pediatric otorhinolaryngology,http://goo.gl/4YdRhz
Wed Feb 26, 2020 14:59
A child with obstructive oral cavity hemorrhagic bullae and refusal to walk.
Related ArticlesA child with obstructive oral cavity hemorrhagic bullae and refusal to walk. Int J Pediatr Otorhinolaryngol. 2020 Feb 20;133:109963 Authors: Boone S, Stein F, Wilson PF, Musso MF PMID: 32097773 [PubMed - as supplied by publisher]
International journal of pediatric otorhinolaryngology,http://goo.gl/4YdRhz
Wed Feb 26, 2020 14:59
Politzer, otitis media with effusion and crenotherapy.
Related ArticlesPolitzer, otitis media with effusion and crenotherapy. Int J Pediatr Otorhinolaryngol. 2020 Feb 21;:109941 Authors: Mudry A PMID: 32093949 [PubMed - as supplied by publisher]
International journal of pediatric otorhinolaryngology,http://goo.gl/4YdRhz
Wed Feb 26, 2020 14:59
Consortium of Otolaryngology Journal Editors: Collegiality and contributions.
Related ArticlesConsortium of Otolaryngology Journal Editors: Collegiality and contributions. Int J Pediatr Otorhinolaryngol. 2020 Feb 19;:109959 Authors: Sataloff RT, Chandra R, Fisher EW, Goldenberg D, Hanna EY, Johnson J, Kennedy DW, Kraus DH, Krouse JH, Link M, Lustig LR, O'Malley BW, Piccirillo JF, Ruben R, Schwartz S, Selesnick SH, Sindwani R, Smith RJ, Stewart MG, Tysome J, Weber PC, Welling DB PMID: 32093948 [PubMed - as supplied by publisher]
International journal of pediatric otorhinolaryngology,http://goo.gl/4YdRhz
Wed Feb 26, 2020 14:59
La Revista Española de Medicina Nuclear e Imagen Molecular en 2020
Publication date: March–April 2020Source: Revista Española de Medicina Nuclear e Imagen Molecular, Volume 39, Issue 2Author(s): M. Mitjavila Casanovas, M.N. Cabrera, V. Camacho, C. De la Fuente, J.R. García, A. Jiménez
Revista Española de Medicina Nuclear e Imagen Molecular
Wed Feb 26, 2020 14:56
Oxidative stress-induced RAC autophagy can improve the HUVEC functions by releasing exosomes.
Related ArticlesOxidative stress-induced RAC autophagy can improve the HUVEC functions by releasing exosomes. J Cell Physiol. 2020 Feb 24;: Authors: Zhu L, Zang J, Liu B, Yu G, Hao L, Liu L, Zhong J Abstract Retinal neovascularization (RNV) is a common pathological feature in many kinds of fundus oculi diseases. Sometimes RNV can even lead to severe vision loss. Oxidative injury is one of the main predisposing factors for RNV occurrence and development....
pubmed: "j cell physiol"[jou...
Wed Feb 26, 2020 14:54
The selective estrogen receptor modulator raloxifene mitigates the effect of all-trans-retinal toxicity in photoreceptor degeneration.
Related ArticlesThe selective estrogen receptor modulator raloxifene mitigates the effect of all-trans-retinal toxicity in photoreceptor degeneration. J Biol Chem. 2019 06 14;294(24):9461-9475 Authors: Getter T, Suh S, Hoang T, Handa JT, Dong Z, Ma X, Chen Y, Blackshaw S, Palczewski K Abstract The retinoid cycle is a metabolic process in the vertebrate retina that continuously regenerates 11-cis-retinal (11-cisRAL) from the all-trans-retinal (atRAL)...
Alcohol and Homeostasis
Wed Feb 26, 2020 14:53
Correction.
Related ArticlesCorrection. Cancer Biol Ther. 2020 Feb 24;:1 Authors: PMID: 32093521 [PubMed - as supplied by publisher]
http://goo.gl/0msigD,Cancer biology and therapy
Wed Feb 26, 2020 14:46
Evaluation of Efficacy of a New Cryoprobe for Transbronchial Cryobiopsy: A Randomized, Controlled in vivo Animal Study
Background: Forceps biopsy (FB) is still the most popular procedure for the bronchoscopic sampling of lung tissue. However, it has limitations like inadequate sample size and crush artifacts. Cryobiopsy (CB) has been introduced to obtain bronchoscopic biopsies with improved diagnostic yield compared to FB. Limitations of CB are the need to retract the cryoprobe en bloc with bronchoscope because samples are larger than the working channel and the variations of the freezing power of the reusable CB...
Respiration
Wed Feb 26, 2020 13:35
Essential Image Acquisition Protocols for Thoracic Ultrasonography
Image acquisition is the technique of correct placement, holding, and manipulation of the ultrasound probe in an ultrasound examination for the purpose of answering a specific clinical question. We review the literature and discuss the image acquisition protocols used for thoracic ultrasound, explaining, where possible, the associated advantages, disadvantages, and alternatives. A better understanding of how to fine-tune image acquisition specifically for thoracic ultrasound will help physicians...
Respiration
Wed Feb 26, 2020 13:34
High-Phosphate Diet Improved the Skeletal Development of <b><i>Fam20c</i></b>-Deficient Mice
FAM20C (family with sequence similarity 20 – member C) is a protein kinase that phosphorylates secretory proteins, including the proteins that are essential to the formation and mineralization of calcified tissues. Previously, we reported that inactivation of Fam20c in mice led to hypophosphatemic rickets/osteomalacia along with increased circulating fibroblast growth factor 23 (FGF23) levels and dental defects. In this study, we examined whether a high-phosphate (hPi) diet could rescue the skeletal...
Cells Tissues Organs
Wed Feb 26, 2020 14:34
Primary lymph node sites in Hodgkin lymphoma and the risk of second primary cancers: a population-based study.
Related ArticlesPrimary lymph node sites in Hodgkin lymphoma and the risk of second primary cancers: a population-based study. Future Oncol. 2020 Feb 25;: Authors: Ebied A, Yousif M, Nam NH, Elhamamsy AR, Hassan OG, Mostafa EM, Nguyen GJ, Hirayama K, Huy NT Abstract Aim: Little is known about the association between specific primary lymph node (LN) sites and the risk of developing second primary cancers in Hodgkin lymphoma (HL) patients. Materials &...
Future Oncology.
Wed Feb 26, 2020 14:43
Sensitivity and specificity of SOAPP-SF questionnaire for predicting aberrant urine drug screen.
Related ArticlesSensitivity and specificity of SOAPP-SF questionnaire for predicting aberrant urine drug screen. Reg Anesth Pain Med. 2020 Feb 23;: Authors: Romman A, Doulatram G, Doctor N, Krishnamurthy P PMID: 32094240 [PubMed - as supplied by publisher]
anesth pain med
Wed Feb 26, 2020 14:42
Postdural puncture headache in the obstetric population: a new approach?
Related ArticlesPostdural puncture headache in the obstetric population: a new approach? Reg Anesth Pain Med. 2020 Feb 23;: Authors: Xavier J, Pinho S, Silva J, Nunes CS, Cabido H, Fortuna R, Araújo R, Lemos P, Machado H Abstract BACKGROUND AND OBJECTIVES: The gold standard for the treatment of postdural puncture headache (PDPH) is the epidural blood patch (EBP). Regional techniques-sphenopalatine ganglion block (SPGB), greater occipital nerve block...
anesth pain med
Wed Feb 26, 2020 14:42
upper respiratory tract infection; +38 new citations
38 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2020/02/26PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Upper respiratory tract infection
Wed Feb 26, 2020 14:32
Perinatal Antecedents of Sleep disturbances in Schoolchildren.
Related ArticlesPerinatal Antecedents of Sleep disturbances in Schoolchildren. Sleep. 2020 Feb 25;: Authors: Brockmann PE, Poggi H, Martinez A, D Apremont I, Moore R, Smith D, Gozal D Abstract STUDY OBJECTIVES: Prematurity has been associated with an increased risk for sleep apnea. However, sleep disturbances in children born preterm have not been extensively investigated. Considering that determinants of sleep may originate early in life, the potential...
pubmed: snoring
Wed Feb 26, 2020 14:32
Polysomnographic Characteristics of Snoring Children: A Familial Study of Obstructive Sleep Apnea Syndrome.
Related ArticlesPolysomnographic Characteristics of Snoring Children: A Familial Study of Obstructive Sleep Apnea Syndrome. Arch Bronconeumol. 2020 Feb 21;: Authors: Morell-Garcia D, Peña-Zarza JA, Sanchís P, Piérola J, de la Peña M, Bauça JM, Toledo-Pons N, Giménez P, Ribot C, Alonso-Fernández A, Barceló A Abstract BACKGROUND AND OBJECTIVES: Available evidence suggests a familial basis for OSA. The aim of the present study was to assess the potential...
pubmed: snoring
Wed Feb 26, 2020 14:32

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