Microorganisms, Vol. 8, Pages 253: Salmonella Extracellular Polymeric Substances Modulate Innate Phagocyte Activity and Enhance Tolerance of Biofilm-Associated Bacteria to Oxidative Stress Microorganisms doi: 10.3390/microorganisms8020253 Authors: Hahn Gunn Salmonella enterica serovar Typhi causes 14.3 million acute cases of typhoid fever that are responsible for 136,000 deaths each year. Chronic infections occur in 3%–5% of those infected and S. Typhi persists primarily...
Thu Feb 13, 2020 02:00
Microorganisms, Vol. 8, Pages 249: Interactions between Magnaporthiopsis maydis and Macrophomina phaseolina, the Causes of Wilt Diseases in Maize and Cotton Microorganisms doi: 10.3390/microorganisms8020249 Authors: Degani Dor Abraham Cohen Fungal pathogens are a significant threat to crops worldwide. The soil fungus, Magnaporthiopsis maydis, severely affects sensitive maize hybrids by causing the rapid wilting of plants at the maturity stage. Similarly, the soil fungus,...
Thu Feb 13, 2020 02:00
Microorganisms, Vol. 8, Pages 252: Antimicrobial Activity of Essential Oils against Staphylococcus and Malassezia Strains Isolated from Canine Dermatitis Microorganisms doi: 10.3390/microorganisms8020252 Authors: Ebani Bertelloni Najar Nardoni Pistelli Mancianti Staphylococcus spp. bacteria are the most frequently involved agents in canine cutaneous infections. Treatment of these infections is based on antibiotic therapy, that often is not effective because of the...
Thu Feb 13, 2020 02:00
Microorganisms, Vol. 8, Pages 251: The Helicobacter pylori HspR-Modulator CbpA Is a Multifunctional Heat-Shock Protein Microorganisms doi: 10.3390/microorganisms8020251 Authors: Pepe Scarlato Roncarati The medically important human pathogen Helicobacter pylori relies on a collection of highly conserved heat-shock and chaperone proteins to preserve the integrity of cellular polypeptides and to control their homeostasis in response to external stress and changing environmental...
Thu Feb 13, 2020 02:00
Microorganisms, Vol. 8, Pages 248: Antimicrobial and Fermentation Potential of Himanthalia elongata in Food Applications Microorganisms doi: 10.3390/microorganisms8020248 Authors: Francesco Martelli Claudia Favari Pedro Mena Stefano Guazzetti Annalisa Ricci Daniele Del Rio Camilla Lazzi Erasmo Neviani Valentina Bernini Himanthalia elongata is a brown oceanic seaweed rich in bioactive compounds. It could play an important role in food production because of its...
Thu Feb 13, 2020 02:00
Microorganisms, Vol. 8, Pages 250: A Novel Moderately Thermophilic Type Ib Methanotroph Isolated from an Alkaline Thermal Spring in the Ethiopian Rift Valley Microorganisms doi: 10.3390/microorganisms8020250 Authors: Islam Gessesse Garcia-Moyano Murrell Øvreås Aerobic moderately thermophilic and thermophilic methane-oxidizing bacteria make a substantial contribution in the control of global warming through biological reduction of methane emissions and have a unique capability...
Thu Feb 13, 2020 02:00
Microorganisms, Vol. 8, Pages 247: Application of a Broad Range Lytic Phage LPST94 for Biological Control of Salmonella in Foods Microorganisms doi: 10.3390/microorganisms8020247 Authors: Md. Sharifull Islam Yang Zhou Lu Liang Ishatur Nime Ting Yan Stephan P. Willias Md. Zakaria Mia Weicheng Bei Ian F. Connerton Vincent A. Fischetti Jinquan Li Salmonella, one of the most common food-borne pathogens, is a significant public health and economic burden worldwide....
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 826: Special Issue “Chemical Speciation of Organic and Inorganic Components of Environmental and Biological Interest in Natural Fluids: Behaviour, Interaction and Sequestration” Molecules doi: 10.3390/molecules25040826 Authors: Crea Pettignano Several different definitions were in the past proposed to describe the term chemical speciation, and some of them were accepted from the scientific community [...]
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 828: Boron Chemistry for Medical Applications Molecules doi: 10.3390/molecules25040828 Authors: Ali Hosmane Zhu Boron compounds now have many applications in a number of fields, including Medicinal Chemistry. Although the uses of boron compounds in pharmacological science have been recognized several decades ago, surprisingly few are found in pharmaceutical drugs. The boron-containing compounds epitomize a new class for medicinal chemists to use in...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 827: Essential Oil Yield and Composition of the Balkan Endemic Satureja pilosa Velen. (Lamiaceae) Molecules doi: 10.3390/molecules25040827 Authors: Semerdjieva Zheljazkov Cantrell Astatkie Ali Satureja pilosa Velen. senso lato is a Balkan endemic plant that is not well characterized and is found on rocky outcrops of limestone base in Stara Planina (the Balkan Mountains) and the Rhodope Mountains. The objective of this study was to assess the...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 822: Analysis of Pollution in High Voltage Insulators via Laser-Induced Breakdown Spectroscopy Molecules doi: 10.3390/molecules25040822 Authors: Wang Lu Wang Qin Wang Jia Surface pollution deposition in a high voltage surface can reduce the surface flashover voltage, which is considered to be a serious accident in the transmission of electric power for the high conductivity of pollution in wet weather, such as rain or fog. Accordingly, a...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 825: Ferritin Nanocages for Protein Delivery to Tumor Cells Molecules doi: 10.3390/molecules25040825 Authors: Palombarini Di Fabio Boffi Macone Bonamore The delivery of therapeutic proteins is one of the greatest challenges in the treatment of human diseases. In this frame, ferritins occupy a very special place. Thanks to their hollow spherical structure, they are used as modular nanocages for the delivery of anticancer drugs. More recently,...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 829: Measuring Sulforaphane and Its Metabolites in Human Plasma: A High Throughput Method Molecules doi: 10.3390/molecules25040829 Authors: Annie Langston-Cox Dovile Anderson Darren J. Creek Kirsten Palmer Euan M. Wallace Sarah A. Marshall (1) Background: There is increasing understanding of the potential health benefits of cruciferous vegetables. In particular sulforaphane (SFN), found in broccoli, and its metabolites sulforaphane-glutathione...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 824: Excited State Dynamics of 8-Vinyldeoxyguanosine In Aqueous Solution Studied by Time-Resolved Fluorescence Spectroscopy and Quantum Mechanical Calculations Molecules doi: 10.3390/molecules25040824 Authors: Martinez-Fernandez Gustavsson Diederichsen Improta The fluorescent base guanine analog, 8-vinyl-deoxyguanosine (8vdG), is studied in solution using a combination of optical spectroscopies, notably femtosecond fluorescence upconversion and...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 823: Virtual Screening Approach to Identify High-Affinity Inhibitors of Serum and Glucocorticoid-Regulated Kinase 1 among Bioactive Natural Products: Combined Molecular Docking and Simulation Studies Molecules doi: 10.3390/molecules25040823 Authors: Mohammad Siddiqui Shamsi Alajmi Hussain Islam Ahmad Hassan Serum and glucocorticoid-regulated kinase 1 (SGK1) is a serine/threonine kinase that works under acute transcriptional control...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 821: Anti-Neuraminidase Bioactives from Manggis Hutan (Garcinia celebica L.) Leaves: Partial Purification and Molecular Characterization Molecules doi: 10.3390/molecules25040821 Authors: Muchtaridi Sugijanto Mohd Gazzali Wahab The neuraminidase enzyme (NA) from the influenza virus is responsible for the proliferation and infections of the virus progeny, prompting several efforts to discover and optimize effective neuraminidase inhibitors. The main...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 817: Lipid Droplet Composition Varies Based on Medaka Fish Eggs Development as Revealed by NIR-, MIR-, and Raman Imaging Molecules doi: 10.3390/molecules25040817 Authors: Bik Ishigaki Blat Jasztal Ozaki Malek Baranska In fertilized fish eggs, lipids are an energy reservoir for the embryo development and substrate for organogenesis. They occur in the cytoplasmic area and form lipid droplets (LDs), but also the yolk egg is composed of...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 819: Green Synthesis of Ag-MnO2 Nanoparticles using Chelidonium majus and Vinca minor Extracts and Their In Vitro Cytotoxicity Molecules doi: 10.3390/molecules25040819 Authors: Ciorîță Suciu Macavei Kacso Lung Soran Pârvu Medicinal plants are often used as reducing agents to prepare metal nanoparticles through green-synthesis due to natural compounds and their potential as chemotherapeutic drugs. Thus, three types of eco-friendly Ag-MnO2...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 820: Effect of Copper on the Mitochondrial Carnitine/Acylcarnitine Carrier Via Interaction with Cys136 and Cys155. Possible Implications in Pathophysiology Molecules doi: 10.3390/molecules25040820 Authors: Nicola Giangregorio Annamaria Tonazzi Lara Console Mario Prejanò Tiziana Marino Nino Russo Cesare Indiveri The effect of copper on the mitochondrial carnitine/acylcarnitine carrier (CAC) was studied. Transport function was assayed as [3H]carnitine/carnitine...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 815: Halogenated Metabolites from the Diet of Aplysia dactylomela Rang Molecules doi: 10.3390/molecules25040815 Authors: Kishneth Palaniveloo Mohammed Rizman-Idid Thilahgavani Nagappan Shariza Abdul Abdul Razak Invertebrates are an important source of structurally-diverse and biologically-active halogenated metabolites. The sea hare Aplysia dactylomela Rang has long been known to possess halogenated metabolites of dietary origin that are used as a self-defense...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 816: Colicin N Mediates Apoptosis and Suppresses Integrin-Modulated Survival in Human Lung Cancer Cells Molecules doi: 10.3390/molecules25040816 Authors: Wanatchaporn Arunmanee Gea Abigail U. Ecoy Hnin Ei Ei Khine Methawee Duangkaew Eakachai Prompetchara Pithi Chanvorachote Chatchai Chaotham The inherent limitations, including serious side-effects and drug resistance, of current chemotherapies necessitate the search for alternative treatments...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 818: Characterization of the Volatiles and Quality of Hybrid Grouper and Their Relationship to Changes of Microbial Community During Storage at 4 °C Molecules doi: 10.3390/molecules25040818 Authors: Huang Xie To investigate the effects of spoilage bacteria on aquatic product quality and volatile organic compounds (VOCs) in hybrid grouper (Epinephelus fuscoguttatus ♀×Epinephelus lanceolatus ♂), the physical conditions were evaluated, the chemical...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 814: Focus on Chemistry of the 10-Dioxane-nido-7,8-dicarba-undecahydrido Undecaborate Zwitterion; Exceptionally Easy Abstraction of Hydrogen Bridge and Double-Action Pathways Observed in Ring Cleavage Reactions with OH− as Nucleophile Molecules doi: 10.3390/molecules25040814 Authors: Mário Bakardjiev Suzan El Anwar Dmytro Bavol Zdeňka Růžičková Bohumír Grűner Ring cleavage of cyclic ether substituents attached to a boron cage via an oxonium oxygen...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 812: Flavonoid Profile of the Genista tridentata L., a Species Used Traditionally to Treat Inflammatory Processes Molecules doi: 10.3390/molecules25040812 Authors: Mark A. M. Simões Diana C. G. A. Pinto Bruno M. R. Neves Artur M. S. Silva Ethnopharmacological surveys on Portuguese flora reveal that Genista tridentata L. is a shrub used in traditional medicine for the treatment of various inflammation-related health problems, although scientific support...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 811: Synthesis of Lactam-Bridged and Lipidated Cyclo-Peptides as Promising Anti-Phytopathogenic Agents Molecules doi: 10.3390/molecules25040811 Authors: Aldrin V. Vasco Martina Brode Yanira Méndez Oscar Valdés Daniel G. Rivera Ludger A. Wessjohann Antimicrobial resistance to conventional antibiotics and the limited alternatives to combat plant-threatening pathogens are worldwide problems. Antibiotic lipopeptides exert remarkable membrane activity,...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 813: Synthesis of the Novel Covalent Cysteine Proteases Inhibitor with Iodoacetic Functional Group Molecules doi: 10.3390/molecules25040813 Authors: Kinga Hartman Przemyslaw Mielczarek Jerzy Silberring This work presents the synthesis of the novel covalent inhibitor of cysteine proteases where epoxide has been replaced by the iodoacetyl functional group. The molecule, similar in action to E-64 and DCG-04, the commonly applied inhibitors, is additionally...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 809: Development of a Unified Reversed-Phase HPLC Method for Efficient Determination of EP and USP Process-Related Impurities in Celecoxib Using Analytical Quality by Design Principles Molecules doi: 10.3390/molecules25040809 Authors: Tim Tome Zdenko Časar Aleš Obreza This article presents the development of a reversed-phase (RP) high-performance liquid chromatographic (HPLC) method for determination of process-related impurities in a celecoxib drug substance...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 810: Effect of Different Green Extraction Methods and Solvents on Bioactive Components of Chamomile (Matricaria chamomilla L.) Flowers Molecules doi: 10.3390/molecules25040810 Authors: Jana Šic Žlabur Ivanka Žutić Sanja Radman Maja Pleša Mladen Brnčić Francisco J. Barba Gabriele Rocchetti Luigi Lucini Jose M. Lorenzo Rubén Domínguez Suzana Rimac Brnčić Ante Galić Sandra Voća Chamomile (Matricaria chamomilla L.) dried flowers...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 806: 1H NMR Metabolic Profile of Scyphomedusa Rhizostoma pulmo (Scyphozoa, Cnidaria) in Female Gonads and Somatic Tissues: Preliminary Results Molecules doi: 10.3390/molecules25040806 Authors: Federica Angilè Laura Del Coco Chiara Roberta Girelli Lorena Basso Lucia Rizzo Stefano Piraino Loredana Stabili Francesco Paolo Fanizzi The Mediterranean basin is one of the regions heavily affected by jellyfish bloom phenomena, mainly due to the presence...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 807: New Ionic Carbosilane Dendrons Possessing Fluorinated Tails at Different Locations on the Skeleton Molecules doi: 10.3390/molecules25040807 Authors: Gabriel Mencia Tania Lozano-Cruz Mercedes Valiente Javier de la Mata Jesús Cano Rafael Gómez The fluorination of dendritic structures has attracted special attention in terms of self-assembly processes and biological applications. The presence of fluorine increases the hydrophobicity of the molecule,...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 808: Targeting Tumors Using Peptides Molecules doi: 10.3390/molecules25040808 Authors: Pablo Scodeller Eliana K. Asciutto To penetrate solid tumors, low molecular weight (Mw < 10 KDa) compounds have an edge over antibodies: their higher penetration because of their small size. Because of the dense stroma and high interstitial fluid pressure of solid tumors, the penetration of higher Mw compounds is unfavored and being small thus becomes an advantage....
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 805: Analysis of Phospholipids, Lysophospholipids, and Their Linked Fatty Acyl Chains in Yellow Lupin Seeds (Lupinus luteus L.) by Liquid Chromatography and Tandem Mass Spectrometry Molecules doi: 10.3390/molecules25040805 Authors: Cosima Damiana Calvano Mariachiara Bianco Giovanni Ventura Ilario Losito Francesco Palmisano Tommaso R.I. Cataldi Hydrophilic interaction liquid chromatography (HILIC) and electrospray ionization (ESI) coupled to either...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 804: Components of Volatile Fractions from Eucalyptus camaldulensis Leaves from Iraqi–Kurdistan and Their Potent Spasmolytic Effects Molecules doi: 10.3390/molecules25040804 Authors: Dlzar A. Kheder Omar A. M. Al-Habib Gianluca Gilardoni Giovanni Vidari Inhalation of vapors from a hot tea of Eucalyptus camaldulensis Dehnh. leaves is considered by Iraqi–Kurdistan people an effective spasmolytic and antipyretic remedy for the treatment of respiratory...
Thu Feb 13, 2020 02:00
Molecules, Vol. 25, Pages 803: Carbon-Supported Raney Nickel Catalyst for Acetone Hydrogenation with High Selectivity Molecules doi: 10.3390/molecules25040803 Authors: Lu Wu Peng Chen Catalysts with high selectivity play key roles in green chemistry. In this work, a granularRaney Ni catalyst using carbon as support (Raney Ni/C) was developed by mixing phenolic resinwith Ni‐Al alloy, conducting carbonization at high temperature, and leaching with alkaline liquor.The as‐prepared...
Thu Feb 13, 2020 02:00
Nanomaterials, Vol. 10, Pages 321: Facile One-Step Hydrothermal Fabrication of (Sr0.6Bi0.305)2Bi2O7/SnO2 Heterojunction with Excellent Photocatalytic Activity Nanomaterials doi: 10.3390/nano10020321 Authors: Zhu Wang An Zhong Wang Tang Hu The pyrochlore-type (Sr0.6Bi0.305)2Bi2O7 (SBO), containing Bi3+ and Bi5+ mixed valent states, was recently found to be used as a new visible light responsive photocatalyst. Novel SBO/SnO2 heterostructured composites were synthesized...
Thu Feb 13, 2020 02:00
Nanomaterials, Vol. 10, Pages 322: Fabrication of Supercritical Antisolvent (SAS) Process-Assisted Fisetin-Encapsulated Poly (Vinyl Pyrrolidone) (PVP) Nanocomposites for Improved Anticancer Therapy Nanomaterials doi: 10.3390/nano10020322 Authors: Chen Xu Fu Kankala Chen Wang Due to its hydrophobicity, fisetin (FIS) often suffers from several limitations in terms of its applicability during the fabrication of pharmaceutical formulations. To overcome this intrinsic...
Thu Feb 13, 2020 02:00
Nanomaterials, Vol. 10, Pages 320: Surface-Dependent Osteoblasts Response to TiO2 Nanotubes of Different Crystallinity Nanomaterials doi: 10.3390/nano10020320 Authors: Khrunyk Belikov Tsurkan Vyalykh Markaryan Karabanalov Popov Wysokowski One of the major challenges of implantology is to design nanoscale modifications of titanium implant surfaces inducing osseointegration. The aim of this study was to investigate the behavior of rat osteoblasts cultured on...
Thu Feb 13, 2020 02:00
Nanomaterials, Vol. 10, Pages 319: Quantitative Flow Cytometric Evaluation of Oxidative Stress and Mitochondrial Impairment in RAW 264.7 Macrophages after Exposure to Pristine, Acid Functionalized, or Annealed Carbon Nanotubes Nanomaterials doi: 10.3390/nano10020319 Authors: Odile Sabido Agathe Figarol Jean-Philippe Klein Valérie Bin Valérie Forest Jérémie Pourchez Bice Fubini Michèle Cottier Maura Tomatis Delphine Boudard Conventional nanotoxicological assays...
Thu Feb 13, 2020 02:00
Nutrients, Vol. 12, Pages 479: Methylglyoxal, Glycated Albumin, PAF, and TNF-α: Possible Inflammatory and Metabolic Biomarkers for Management of Gestational Diabetes Nutrients doi: 10.3390/nu12020479 Authors: Gabriele Piuri Katia Basello Gabriele Rossi Chiara Maria Soldavini Silvia Duiella Giulia Privitera Angela Spadafranca Andrea Costanzi Emiliana Tognon Mattia Cappelletti Paola Antonia Corsetto Angela Maria Rizzo Attilio Francesco Speciani Enrico Ferrazzi...
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