Membranes, Vol. 10, Pages 28: The Function of Adsorption, Photo-Oxidation, and Humic Acid Using Air Backwashing in Integrated Water Treatment of Multichannel Ceramic MF and PP Particles Membranes doi: 10.3390/membranes10020028 Authors: Park Kim Park For advanced water treatment, function of microfiltration (MF), adsorption, photo-oxidation, humic acid (HA), and polypropylene (PP) particles on membrane fouling and decay effectiveness were investigated in an integrated water treatment,...
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Metabolites, Vol. 10, Pages 66: EFMviz: A COBRA Toolbox extension to visualize Elementary Flux Modes in Genome-Scale Metabolic Models Metabolites doi: 10.3390/metabo10020066 Authors: Chaitra Sarathy Martina Kutmon Michael Lenz Michiel E. Adriaens Chris T. Evelo Ilja C.W. Arts Elementary Flux Modes (EFMs) are a tool for constraint-based modeling and metabolic network analysis. However, systematic and automated visualization of EFMs, capable of integrating various data types...
Metabolites, Vol. 10, Pages 65: In Vivo Rate of Formaldehyde Condensation with Tetrahydrofolate Metabolites doi: 10.3390/metabo10020065 Authors: He Noor Ramos-Parra García-Valencia Patterson Díaz de la Garza Hanson Bar-Even Formaldehyde is a highly reactive compound that participates in multiple spontaneous reactions, but these are mostly deleterious and damage cellular components. In contrast, the spontaneous condensation of formaldehyde with tetrahydrofolate...
Metabolites, Vol. 10, Pages 64: Seminal Fluid Metabolomic Markers of Oligozoospermic Infertility in Humans Metabolites doi: 10.3390/metabo10020064 Authors: Murgia Corda Serrenti Usai Santoru Hurt Passaretti Monni Atzori Monni Infertility affects 12–15% of couples worldwide, and male factors are the cause of nearly half of all cases. Studying seminal fluid composition could lead to additional diagnostic accuracy and a better understanding...
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MPs, Vol. 3, Pages 16: Antimicrobial Lock Therapy in Clinical Practice: A Scoping Review Protocol Methods and Protocols doi: 10.3390/mps3010016 Authors: Alfieri Di Franco Passavanti Pace Stanga Simeon Chiodini Leone Niyas Fiore Our objective is to review the scientific literature on the use of antimicrobial lock therapy (ALT). To achieve this result, our scoping review will address the following seven key questions: 1) Who are the patients who will...
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Microorganisms, Vol. 8, Pages 246: Detection Methods for Aflatoxin M1 in Dairy Products Microorganisms doi: 10.3390/microorganisms8020246 Authors: Vaz Cabral Silva Rodrigues Venâncio Mycotoxins are toxic compounds produced mainly by fungi of the genera Aspergillus, Fusarium and Penicillium. In the food chain, the original mycotoxin may be transformed in other toxic compounds, reaching the consumer. A good example is the occurrence of aflatoxin M1 (AFM1) in dairy products,...
Microorganisms, Vol. 8, Pages 244: Responses of Acidobacteria Granulicella sp. WH15 to High Carbon Revealed by Integrated Omics Analyses Microorganisms doi: 10.3390/microorganisms8020244 Authors: Costa Zerillo Zühlke Kielak Pijl Riedel Kuramae The phylum Acidobacteria is widely distributed in soils, but few representatives have been cultured. In general, Acidobacteria are oligotrophs and exhibit slow growth under laboratory conditions. We sequenced the genome...
Microorganisms, Vol. 8, Pages 243: Propolis Affects Pseudomonas aeruginosa Growth, Biofilm Formation, eDNA Release and Phenazine Production: Potential Involvement of Polyphenols Microorganisms doi: 10.3390/microorganisms8020243 Authors: Meto Colombari Meto Boaretto Pinetti Marchetti Benvenuti Pellati Blasi Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic pathogen responsible for a wide range of clinical conditions, from mild infections to life-threatening...
Microorganisms, Vol. 8, Pages 242: Reply to Comment on “Enumeration of Escherichia coli in Probiotic Products. Microorganisms 2019, 7. 437” Microorganisms doi: 10.3390/microorganisms8020242 Authors: Zimmer Dorea We thank Wassenaar and colleagues for their Comment on our recent paper [1] and appreciate the opportunity to address it [...]
Microorganisms, Vol. 8, Pages 245: Comment on “Enumeration of Escherichia coli in Probiotic Products. Microorganisms 2019, 7, 437” Microorganisms doi: 10.3390/microorganisms8020245 Authors: Wassenaar von Bünau Zimmermann Recently, Zimmer and Dorea published a communication on the enumeration of Escherichia coli in probiotic products containing this species [...]
Microorganisms, Vol. 8, Pages 241: In Vitro Fumonisin Biosynthesis and Genetic Structure of Fusarium verticillioides Strains from Five Mediterranean Countries Microorganisms doi: 10.3390/microorganisms8020241 Authors: Beccari Stępień Onofri Lattanzio Ciasca Fatah Valente Urbaniak Covarelli Investigating the in vitro fumonisin biosynthesis and the genetic structure of Fusarium verticillioides populations can provide important insights into the relationships...
Microorganisms, Vol. 8, Pages 240: Interactions between Kazachstania humilis Yeast Species and Lactic Acid Bacteria in Sourdough Microorganisms doi: 10.3390/microorganisms8020240 Authors: Carbonetto Nidelet Guezenec Perez Segond Sicard Sourdoughs harbor simple microbial communities usually composed of a few prevailing lactic acid bacteria species (LAB) and yeast species. However, yeast and LAB found in sourdough have been described as highly diverse. Even if LAB...
Microorganisms, Vol. 8, Pages 239: High-Level Production of Bacteriotoxic Phospholipase A1 in Bacterial Host Pseudomonas fluorescens Via ABC Transporter-Mediated Secretion and Inducible Expression Microorganisms doi: 10.3390/microorganisms8020239 Authors: Park Eom Young Oh Hyun Park Kim Kwang Song Hoon Ahn : Bacterial phospholipase A1 (PLA1) is used in various industrial fields because it can catalyze the hydrolysis, esterification, and transesterification of...
Microorganisms, Vol. 8, Pages 238: Use of Lactic Acid Bacteria During Pikeperch (Sander lucioperca) Larval Rearing Microorganisms doi: 10.3390/microorganisms8020238 Authors: Yanes-Roca Leclercq Vesely Malinovskyi Policar This trial tested the use of lactic acid bacteria (LAB) on pikeperch (Sander lucioperca) larvae during their first feeding. The trial included the use of two probiotic treatments and one control (no probiotics). Pikeperch larvae were exposed to LAB as...
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Molecules, Vol. 25, Pages 802: Catalytic Production of Jet Fuels from Biomass Molecules doi: 10.3390/molecules25040802 Authors: Díaz-Pérez Serrano-Ruiz Concerns about depleting fossil fuels and global warming effects are pushing our society to search for new renewable sources of energy with the potential to substitute coal, natural gas, and petroleum. In this sense, biomass, the only renewable source of carbon available on Earth, is the perfect replacement for petroleum in producing...
Molecules, Vol. 25, Pages 800: Synthesis and Evaluation of Antileishmanial and Cytotoxic Activity of Benzothiopyrane Derivatives Molecules doi: 10.3390/molecules25040800 Authors: Cristian Ortiz Fernando Echeverri Sara Robledo Daniela Lanari Massimo Curini Wiston Quiñones Esteban Vargas In continuation of our efforts to identify promising antileishmanial agents based on the chroman scaffold, we synthesized several substituted 2H-thiochroman derivatives, including thiochromenes,...
Molecules, Vol. 25, Pages 799: 5-Trifluoromethyl-2-formylphenylboronic Acid Molecules doi: 10.3390/molecules25040799 Authors: Adamczyk-Woźniak Gozdalik Wieczorek Madura Kaczorowska Brzezińska Sporzyński Lipok 2-Formylphenylboronic acids display many interesting features, not only from synthetic but also from an application as well as structural points of view. 5-Trifluoromethyl-2-formyl phenylboronic acid has been synthesized and characterized in terms of...
Molecules, Vol. 25, Pages 798: Anion Recognition by Neutral and Cationic Iodotriazole Halogen Bonding Scaffolds Molecules doi: 10.3390/molecules25040798 Authors: Iribarren Sánchez-Sanz Trujillo A computational study of the iodide discrimination by different neutral and cationic iodotriazole halogen bonding hosts was carried out by means of Density Functional Theory. The importance of the size of the scaffold was highlighted and its impact observed in the binding energies and...
Molecules, Vol. 25, Pages 801: Two New Apotirucallane-Type Triterpenoids from the Pericarp of Toona sinensis and Their Ability to Reduce Oxidative Stress in Rat Glomerular Mesangial Cells Cultured under High-Glucose Conditions Molecules doi: 10.3390/molecules25040801 Authors: Liu Wang Xuan Wang Li Hyperglycemia is a strong risk factor for chronic complications of diabetes. Hyperglycemic conditions foster not only the production of reactive oxygen species (ROS), but also...
Molecules, Vol. 25, Pages 796: Towards the Preparation of Stable Cyclic Amino(ylide)Carbenes Molecules doi: 10.3390/molecules25040796 Authors: Steinert Schwarz Kroll Gessner Cyclic amino(ylide)carbenes (CAYCs) are the ylide-substituted analogues of N-heterocyclic Carbenes (NHCs). Due to the stronger π donation of the ylide compared to an amino moiety they are stronger donors and thus are desirable ligands for catalysis. However, no stable CAYC has been reported until...
Molecules, Vol. 25, Pages 789: Synthesis and Antibacterial Activity of Difluoromethyl Cinnamoyl Amides Molecules doi: 10.3390/molecules25040789 Authors: Martínez Riva Garcia Durán Burton Series of novel amides of isoferulic acid, where the phenolic hydroxyl was replaced by a difluoromethyl group, were synthesized and their in vitro antibacterial activities assayed against fourteen bacterial strains (six Gram-positive and eight Gram-negative). A one-pot methodology was...
Molecules, Vol. 25, Pages 795: Bioorthogonal Labeling Reveals Different Expression of Glycans in Mouse Hippocampal Neuron Cultures during Their Development Molecules doi: 10.3390/molecules25040795 Authors: Soares da Costa Sousa Dá Mesquita Petkova-Yankova Marques Reis Sousa Pashkuleva The expression of different glycans at the cell surface dictates cell interactions with their environment and other cells, being crucial for the cell fate. The development of...
Molecules, Vol. 25, Pages 794: Biological Activity Profiles of Multitarget Ligands from X-ray Structures Molecules doi: 10.3390/molecules25040794 Authors: Christian Feldmann Jürgen Bajorath In pharmaceutical research, compounds with multitarget activity receive increasing attention. Such promiscuous chemical entities are prime candidates for polypharmacology, but also prone to causing undesired side effects. In addition, understanding the molecular basis and magnitude of multitarget...
Molecules, Vol. 25, Pages 790: Design, Synthesis, and Antimicrobial Activities of 1,2,3-Triazole Glycoside Clickamers Molecules doi: 10.3390/molecules25040790 Authors: Tamer El Malah Hany F. Nour Amira A. E. Satti Bahaa A. Hemdan Wael A. El-Sayed Bacterial resistance remains a significant threat and a leading cause of death worldwide, despite massive attempts to control infections. In an effort to develop biologically active antibacterial and antifungal agents, six novel...
Molecules, Vol. 25, Pages 793: Metronidazole and Secnidazole Carbamates: Synthesis, Antiprotozoal Activity, and Molecular Dynamics Studies Molecules doi: 10.3390/molecules25040793 Authors: Rocha-Garduño Hernández-Martínez Colín-Lozano Estrada-Soto Hernández-Núñez Prieto-Martínez Medina-Franco Chale-Dzul Moo-Puc Navarrete-Vázquez We prepared a series of 10 carbamates derivatives based on two common antiprotozoal drugs: metronidazole (1–5)...
Molecules, Vol. 25, Pages 792: Listeria Monocytogenes Biofilm Removal Using Different Commercial Cleaning Agents Molecules doi: 10.3390/molecules25040792 Authors: Fagerlund Heir Møretrø Langsrud Effective cleaning and disinfection (C&D) is pivotal for the control of Listeria monocytogenes in food processing environments. Bacteria in biofilms are protected from biocidal action, and effective strategies for the prevention and removal of biofilms are needed. In this...
Molecules, Vol. 25, Pages 791: Characterization and Antioxidant Activity Determination of Neutral and Acidic Polysaccharides from Panax Ginseng C. A. Meyer Molecules doi: 10.3390/molecules25040791 Authors: Kim Song Hyun Long Park Hsieh Kwon Panax ginseng (P. ginseng) is the most widely consumed herbal plant in Asia and is well-known for its various pharmacological properties. Many studies have been devoted to this natural product. However, polysaccharide's components...
Molecules, Vol. 25, Pages 797: Synthetic Approaches to A Challenging and Unusual Structure—An Amino-Pyrrolidine Guanine Core Molecules doi: 10.3390/molecules25040797 Authors: Rippel Pinheiro Lopes Lourenço Ferreira Branco The synthesis of an unreported 2-aminopyrrolidine-1-carboxamidine unit is here described for the first time. This unusual and promising structure was attained through the oxidative decarboxylation of amino acids using the pair of reagents, silver(I)/peroxydisulfate...
Molecules, Vol. 25, Pages 782: Effect of Collagen Peptide, Alone and in Combination with Calcium Citrate, on Bone Loss in Tail-Suspended Rats Molecules doi: 10.3390/molecules25040782 Authors: Liu Wang Guo Oral administration of bovine collagen peptide (CP) combined with calcium citrate (CC) has been found to inhibit bone loss in ovariectomized rats. However, the protective effects of CP and CP–CC against bone loss have not been investigated in a tail-suspension simulated...
Molecules, Vol. 25, Pages 784: Kinetics Study of Microwave-Assisted Brine Extraction of Lipid from the Microalgae Nannochloropsis sp. Molecules doi: 10.3390/molecules25040784 Authors: Zghaibi Omar Kamal Biak Harun The kinetics of lipid extraction utilizing microwave-assisted extraction (MAE) from Nannochloropsis sp. microalgae were studied using a low cost and green solvent, namely brine (NaCl) solution. The kinetic modelling of the lipid extraction was performed to...
Molecules, Vol. 25, Pages 787: Optimization of Total Phenolic and Flavonoid Contents of Defatted Pitaya (Hylocereus polyrhizus) Seed Extract and Its Antioxidant Properties Molecules doi: 10.3390/molecules25040787 Authors: Zulkifli Abd Gani Zaidan Halmi The present study was conducted to optimize extraction process for defatted pitaya seed extract (DPSE) adopting response surface methodology (RSM). A five-level central composite design was used to optimize total phenolic...
Molecules, Vol. 25, Pages 788: In Vitro Propagation and Variation of Antioxidant Properties in Micropropagated Vaccinium Berry Plants—A Review Molecules doi: 10.3390/molecules25040788 Authors: Debnath Goyali The berry crops in genus Vacciniun L. are the richest sources of antioxidant metabolites which have high potential to reduce the incidence of several degenerative diseases. In vitro propagation or micropropagation has been attractive to researchers for its incredible potential...
Molecules, Vol. 25, Pages 786: PNA Clamping in Nucleic Acid Amplification Protocols to Detect Single Nucleotide Mutations Related to Cancer Molecules doi: 10.3390/molecules25040786 Authors: Fouz Appella This review describes the application of peptide nucleic acids (PNAs) as clamps that prevent nucleic acid amplification of wild-type DNA so that DNA with mutations may be observed. These methods are useful to detect single-nucleotide polymorphisms (SNPs) in cases where there is a...
Molecules, Vol. 25, Pages 783: First Report on Yield and Chemical Composition of Essential Oil Extracted from Myrcia eximia DC (Myrtaceae) from the Brazilian Amazon Molecules doi: 10.3390/molecules25040783 Authors: Ferreira da Cruz Franco Silva da Costa de Oliveira Andrade The essential oil (EO) of plants of the Myrtaceae family has diverse chemical composition and several applications. However, data on the oil yield, its composition, and its complete chemistry...
Molecules, Vol. 25, Pages 785: Demonstration of Solar Cell on a Graphite Sheet with Carbon Diffusion Barrier Evaluation Molecules doi: 10.3390/molecules25040785 Authors: Cho Kim Park Kim Kim Oh Ko An amorphous Si (a-Si) solar cell with a back reflector composed of zinc oxide (ZnO) and silver (Ag) is potentially the most plausible and flexible solar cell if a graphite sheet is used as the substrate. Graphite supplies lightness, conductivity and flexibility to...
Molecules, Vol. 25, Pages 781: Ready Access to Molecular Rotors Based on Boron Dipyrromethene Dyes-Coumarin Dyads Featuring Broadband Absorption Molecules doi: 10.3390/molecules25040781 Authors: Enríquez-Palacios Arbeloa Bañuelos Bautista-Hernández Becerra-González López-Arbeloa Peña-Cabrera Herein we report on a straightforward access method for boron dipyrromethene dyes (BODIPYs)-coumarin hybrids linked through their respective 8- and 6- positions, with wide...
Molecules, Vol. 25, Pages 780: Destabilization of NaBH4 by Transition Metal Fluorides Molecules doi: 10.3390/molecules25040780 Authors: Isabel Llamas Llamas Jansa Georgios N. Kalantzopoulos Kari Nordholm Bjørn C. Hauback In order to improve the suitability of NaBH4 as a clean fuel, its decomposition temperature needs to be decreased to below 535 °C, while its hydrogen release must be as high as possible. In this work, the influence of a collection of first and second...
Molecules, Vol. 25, Pages 778: Adsorption and Desorption Properties of Total Flavonoids from Oil Palm (Elaeis guineensis Jacq.) Mature Leaf on Macroporous Adsorption Resins Molecules doi: 10.3390/molecules25040778 Authors: Che Zain Lee Teo Shaari Three different macroporous resins (XAD7HP, DAX-8, and XAD4) were evaluated for their adsorption and desorption properties in preparing flavonoid-enriched oil palm (Elaeis guineensis Jacq.) leaf extract. The influences of initial...
Molecules, Vol. 25, Pages 779: Rapid Evaluation and Optimization of Medium Components Governing Tryptophan Production by Pediococcus acidilactici TP-6 Isolated from Malaysian Food via Statistical Approaches Molecules doi: 10.3390/molecules25040779 Authors: Lim Foo Loh Mohamad Abdul Rahim Tryptophan is one of the most extensively used amino acids in livestock industry owing to its effectiveness in enhancing the growth performance of animals. Conventionally, the production...
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