Cells, Vol. 9, Pages 414: Activation of Astroglial Connexin is Involved in Concentration-Dependent Double-Edged Sword Clinical Action of Clozapine Cells doi: 10.3390/cells9020414 Authors: Fukuyama Okubo Murata Shiroyama Okada Clozapine (CLZ) is a gold-standard antipsychotic against treatment-refractory schizophrenia, but is one of the most toxic antipsychotic agents. Pharmacological mechanisms of the double-edged sword clinical action of CLZ remain to be clarified. To...
Tue Feb 11, 2020 02:00
Cells, Vol. 9, Pages 418: Paracrine Signaling from Breast Cancer Cells Causes Activation of ID4 Expression in Tumor-Associated Macrophages Cells doi: 10.3390/cells9020418 Authors: Donzelli Sacconi Turco Gallo Milano Iosue Blandino Fazi Fontemaggi Background: Tumor-associated macrophages (TAMs) constitute a major portion of the leukocyte infiltrate found in breast cancer (BC). BC cells may reprogram TAMs in a pro-angiogenic and immunosuppressive sense....
Tue Feb 11, 2020 02:00
Cells, Vol. 9, Pages 412: Astrocyte Infection during Rabies Encephalitis Depends on the Virus Strain and Infection Route as Demonstrated by Novel Quantitative 3D Analysis of Cell Tropism Cells doi: 10.3390/cells9020412 Authors: Potratz Zaeck Christen te Kamp Klein Nolden Freuling Müller Finke Although conventional immunohistochemistry for neurotropic rabies virus (RABV) usually shows high preference for neurons, non-neuronal cells are also potential targets,...
Tue Feb 11, 2020 02:00
Cells, Vol. 9, Pages 413: Shaping Pancreatic β-Cell Differentiation and Functioning: The Influence of Mechanotransduction Cells doi: 10.3390/cells9020413 Authors: Galli Algerta Marciani Schulte Lenardi Milani Maffioli Tedeschi Perego Embryonic and pluripotent stem cells hold great promise in generating β-cells for both replacing medicine and novel therapeutic discoveries in diabetes mellitus. However, their differentiation in vitro is still inefficient,...
Tue Feb 11, 2020 02:00
Cells, Vol. 9, Pages 409: Tendon Extracellular Matrix Remodeling and Defective Cell Polarization in the Presence of Collagen VI Mutations Cells doi: 10.3390/cells9020409 Authors: Antoniel Traina Merlini Andrenacci Tigani Santi Cenni Sabatelli Faldini Squarzoni Mutations in collagen VI genes cause two major clinical myopathies, Bethlem myopathy (BM) and Ullrich congenital muscular dystrophy (UCMD), and the rarer myosclerosis myopathy. In addition to...
Tue Feb 11, 2020 02:00
Cells, Vol. 9, Pages 411: Matrix Metalloproteinases Retain Soluble FasL-mediated Resistance to Cell Death in Fibrotic-Lung Myofibroblasts Cells doi: 10.3390/cells9020411 Authors: Nareznoi Konikov-Rozenman Petukhov Breuer Wallach-Dayan A prominent feature of obstructed tissue regeneration following injury in general, and fibrotic lung tissue in particular, is fibroblast proliferation and accumulation. The Fas/FasL apoptotic pathway has been shown to be involved in human...
Tue Feb 11, 2020 02:00
Cells, Vol. 9, Pages 408: ER-to-Golgi Trafficking and Its Implication in Neurological Diseases Cells doi: 10.3390/cells9020408 Authors: Wang Stanford Kundu Membrane and secretory proteins are essential for almost every aspect of cellular function. These proteins are incorporated into ER-derived carriers and transported to the Golgi before being sorted for delivery to their final destination. Although ER-to-Golgi trafficking is highly conserved among eukaryotes, several layers...
Tue Feb 11, 2020 02:00
Cells, Vol. 9, Pages 410: Long-Term Survival of Transplanted Autologous Canine Liver Organoids in a COMMD1-Deficient Dog Model of Metabolic Liver Disease Cells doi: 10.3390/cells9020410 Authors: Kruitwagen Oosterhoff van Wolferen Chen Nantasanti Assawarachan Schneeberger Kummeling van Straten Akkerdaas Vinke van Steenbeek van Bruggen Wolfswinkel Grinwis Fuchs Gehart Geijsen Vries Clevers Rothuizen Schotanus ...
Tue Feb 11, 2020 02:00
Cells, Vol. 9, Pages 407: Complex Mitochondrial Dysfunction Induced by TPP+-Gentisic Acid and Mitochondrial Translation Inhibition by Doxycycline Evokes Synergistic Lethality in Breast Cancer Cells Cells doi: 10.3390/cells9020407 Authors: Fuentes-Retamal Sandoval-Acuña Peredo-Silva Guzmán-Rivera Pavani Torrealba Truksa Castro-Castillo Catalán Kemmerling Urra Ferreira The mitochondrion has emerged as a promising therapeutic target for novel...
Tue Feb 11, 2020 02:00
Cells, Vol. 9, Pages 405: Tumor Necrosis Factor-Like Weak Inducer of Apoptosis (TWEAK)/Fibroblast Growth Factor-Inducible 14 (Fn14) Axis in Cardiovascular Diseases: Progress and Challenges Cells doi: 10.3390/cells9020405 Authors: Méndez-Barbero Gutiérrez-Muñoz Blázquez-Serra Martín-Ventura Blanco-Colio Cardiovascular diseases (CVD) are the leading cause of mortality in Western countries. CVD include several pathologies, such as coronary artery disease, stroke, peripheral...
Tue Feb 11, 2020 02:00
Cells, Vol. 9, Pages 406: Future Therapeutic Directions for Smac-Mimetics Cells doi: 10.3390/cells9020406 Authors: Morrish Brumatti Silke It is well accepted that the ability of cancer cells to circumvent the cell death program that untransformed cells are subject to helps promote tumor growth. Strategies designed to reinstate the cell death program in cancer cells have therefore been investigated for decades. Overexpression of members of the Inhibitor of APoptosis (IAP) protein...
Tue Feb 11, 2020 02:00
Cells, Vol. 9, Pages 404: mTOR Regulation of Metabolism in Hematologic Malignancies Cells doi: 10.3390/cells9020404 Authors: Mirabilii Ricciardi Tafuri Neoplastic cells rewire their metabolism, acquiring a selective advantage over normal cells and a protection from therapeutic agents. The mammalian Target of Rapamycin (mTOR) is a serine/threonine kinase involved in a variety of cellular activities, including the control of metabolic processes. mTOR is hyperactivated in a large...
Tue Feb 11, 2020 02:00
Chemosensors, Vol. 8, Pages 12: Towards an Integrated System as Point-of-Care Device for the Optical Detection of Sepsis Biomarkers Chemosensors doi: 10.3390/chemosensors8010012 Authors: Giannetti Trono Porro Domenici Puntoni Baldini Severe infection and sepsis are a common, expensive, and frequently fatal conditions in critically ill patients. The sepsis diagnosis is not trivial, since it is an extremely complex chain of events involving inflammatory and anti-inflammatory...
Tue Feb 11, 2020 02:00
Climate, Vol. 8, Pages 32: Correction: Péres, W. E., et al. The Association between Air Temperature and Mortality in Two Brazilian Health Regions. Climate, 2020, 8, 1 Climate doi: 10.3390/cli8020032 Authors: Péres Ribeiro Russo Nunes The authors wish to make the following correction to this paper [1] [...]
Wed Feb 12, 2020 02:00
Clocks & Sleep, Vol. 2, Pages 54-60: Lucid Dreaming and the Feeling of Being Refreshed in the Morning: A Diary Study Clocks & Sleep doi: 10.3390/clockssleep2010007 Authors: Schredl Dyck Kühnel REM periods with lucid dreaming show increased brain activation, especially in the prefrontal cortex, compared to REM periods without lucid dreaming and, thus, the question of whether lucid dreaming interferes with the recovery function of sleep arises. Cross-sectional studies...
Wed Feb 12, 2020 02:00
Cosmetics, Vol. 7, Pages 10: Non-Traditional and Non-Invasive Approaches in Facial Rejuvenation: A Brief Review Cosmetics doi: 10.3390/cosmetics7010010 Authors: M. Smith Ferris K. Nahar Sharma While injectables, lasers, and surgical interventions have traditionally been used to reverse the changes associated with facial aging, other alternative therapies such as facial acupuncture and facial exercises are now being studied for facial rejuvenation. In this paper, we both...
Wed Feb 12, 2020 02:00
Cosmetics, Vol. 7, Pages 11: Multivariate Analysis of Olfactory Profiles for 140 Perfumes as a Basis to Derive a Sensory Wheel for the Classification of Feminine Fragrances Cosmetics doi: 10.3390/cosmetics7010011 Authors: Zarzo In order to guide consumers in their purchase of a new fragrance, one approach is to visualize the spectrum of men’s or women’s fragrances on a two-dimensional plot. One of such sensory maps available is the Hexagon of Fragrance Families....
Wed Feb 12, 2020 02:00
Diagnostics, Vol. 10, Pages 101: Diagnostic Performance of 18F-FDG PET or PET/CT for Detection of Post-Transplant Lymphoproliferative Disorder: A Systematic Review and a Bivariate Meta-Analysis Diagnostics doi: 10.3390/diagnostics10020101 Authors: Ballova Muoio Albano Bertagna Canziani Ghielmini Ceriani Treglia Background: Some studies evaluated the diagnostic performance of fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomography or positron...
Wed Feb 12, 2020 02:00
Diagnostics, Vol. 10, Pages 100: Skeletal Muscle Metastasis in Papillary Thyroid Microcarcinoma Evaluated by F18-FDG PET/CT Diagnostics doi: 10.3390/diagnostics10020100 Authors: Hitu Cainap Apostu Gabora Bonci Badan Mester Piciu Papillary thyroid cancer (PTC) is the most common type of thyroid malignancy and is characterized by slow growth and an indolent biological behavior. Papillary thyroid microcarcinoma is the PTC with the maximum size of the tumor <1cm,...
Wed Feb 12, 2020 02:00
Diagnostics, Vol. 10, Pages 98: Multidisciplinary Diagnostic Algorithm for Evaluation of Patients Presenting with a Prosthetic Problem in the Hip or Knee: A Prospective Study Diagnostics doi: 10.3390/diagnostics10020098 Authors: Khalid Schønheyder Larsen Nielsen Kappel Thomsen Aleksyniene Lorenzen Ørsted Simonsen Jordal Rasmussen The predominant indications for revision surgery after total hip (THA) or knee arthroplasty (TKA) are an aseptic...
Tue Feb 11, 2020 02:00
Diagnostics, Vol. 10, Pages 99: A Rare Case of Sigmoid Colon Carcinoma in Incarcerated Inguinal Hernia Diagnostics doi: 10.3390/diagnostics10020099 Authors: Baldi Alfano Punzo Tramontano Baselice Spidalieri Micera Cavaliere Incarcerated inguinal hernia is a common diagnosis in patients presenting a painful and nonreducible groin mass. Although the diagnosis is usually made by physical examination, the content of the hernia sac and the extent of the surgical...
Tue Feb 11, 2020 02:00
Diagnostics, Vol. 10, Pages 97: Detection of Occult Metastases in Patients with T1 and T2 Stage Lower Lip Squamous Cell Carcinomas after Positive Lymphoscintigraphy Diagnostics doi: 10.3390/diagnostics10020097 Authors: Loxha Stubljar Jukic Rusinovci The aim of this study was to detect lower lip squamous cell carcinomas (SCC) that had metastasized to the lymph nodes and to evaluate if neck dissection was necessary for patients with T1 or T2-stage lip cancer after a sentinel...
Tue Feb 11, 2020 02:00
Diagnostics, Vol. 10, Pages 96: Diagnostic Dilemma of Recurrent Pulmonary Embolism Diagnostics doi: 10.3390/diagnostics10020096 Authors: Dadarlat-Pop Burian Cadis Tomoaia Oprea Popliteal venous aneurysms are rare vascular disorders associated with a high risk of pulmonary embolism. We present the case of a 56-year-old woman hospitalized for a third episode of unprovoked pulmonary embolism. Venous ultrasonography identified a popliteal aneurysm, repeatedly missed by two-point...
Tue Feb 11, 2020 02:00
Diversity, Vol. 12, Pages 73: Respiration by the Opportunistic Spionid Polychaete Streblospio gynobranchiata during Adjustment to and Recovery from Moderate Hypoxia Diversity doi: 10.3390/d12020073 Authors: Bennett Rakocinski Understanding the capacity of estuarine organisms to acclimate to stressful conditions provides insights into how communities cope within fluctuating environments. The opportunistic spionid polychaete, Streblospio gynobranchiata Rice and Levin, 1998, regularly...
Wed Feb 12, 2020 02:00
Diversity, Vol. 12, Pages 74: Livelihood, Food and Nutrition Security in Southern Africa: What Role Do Indigenous Cattle Genetic Resources Play? Diversity doi: 10.3390/d12020074 Authors: Mapiye Chikwanha Makombe Dzama Mapiye Of the 345 million people in the Southern African Development Community (SADC), 30.6% are severely food insecure, 8% malnourished and 50% live with less than US $1 per day, respectively. Livelihood, food and nutrition security have, therefore, become...
Wed Feb 12, 2020 02:00
Diversity, Vol. 12, Pages 72: Urbanization and Human Population Favor Species Richness of Alien Birds Diversity doi: 10.3390/d12020072 Authors: Lazarina Tsianou Boutsis Andrikou – Charitidou Karadimou Kallimanis Human activities like urbanization and agriculture affect spatial biodiversity patterns. The presence and activities of humans richly benefit alien species, but native species usually decline in human-impacted areas. Considering that the richness of alien...
Tue Feb 11, 2020 02:00
Diversity, Vol. 12, Pages 71: Priority Treatment Leaves Grassland Restoration Vulnerable to Invasion
Diversity, Vol. 12, Pages 71: Priority Treatment Leaves Grassland Restoration Vulnerable to Invasion Diversity doi: 10.3390/d12020071 Authors: Stuble Young Priority effects can be used to promote target species during restoration. Early planting can provide an advantage over later-arriving species, increasing abundance of these early-arrivers in restored communities. However, we have limited knowledge of the indirect impacts of priority effects in restoration. In particular, we...
Tue Feb 11, 2020 02:00
Environments, Vol. 7, Pages 13: Cyanobacteria: Review of Current Potentials and Applications Environments doi: 10.3390/environments7020013 Authors: Zahra Choo Lee Parveen Continual increases in the human population and growing concerns related to the energy crisis, food security, disease outbreaks, global warming, and other environmental issues require a sustainable solution from nature. One of the promising resources is cyanobacteria, also known as blue-green algae. They...
Wed Feb 12, 2020 02:00
Environments, Vol. 7, Pages 14: Hydrological and Environmental Impact of Wastewater Treatment and Reuse on Zarqa River Basin in Jordan Environments doi: 10.3390/environments7020014 Authors: Almanaseer Hindiyeh Al-Assaf Treated wastewater is an important component of the water resource in Jordan. As Samra wastewater treatment plant—the largest treatment plant in Jordan—discharges ~110 MCM per year of secondary treated municipal wastewater to Zarqa River, and...
Wed Feb 12, 2020 02:00
Environments, Vol. 7, Pages 12: Measurements of 22Na in the Atmosphere: Ground Level Activity Concentration Values from Wet and Dry Deposition Samples Environments doi: 10.3390/environments7020012 Authors: Magnoni Bellina Bertino Bellotto Ghione Losana Sodium-22 (22Na, half-life 2.603 years) is a cosmogenic radionuclide mainly produced in the stratosphere by nuclear spallation reactions of cosmic rays on 40Ar. Due to the very low concentration levels normally reached...
Tue Feb 11, 2020 02:00
Fermentation, Vol. 6, Pages 24: Assessment of Pomegranate Juice as an Alternative “Substrate” for Probiotic Delivery. Recent Advances and Prospects Fermentation doi: 10.3390/fermentation6010024 Authors: Kazakos Mantzourani Plessas The probiotic products in the market are mostly milk-based products, such as yoghurts, cheese and fermented milk. However, lately, there has been an increasing demand for non-dairy probiotic products due to various reasons such as allergies, lactose...
Wed Feb 12, 2020 02:00
Foods, Vol. 9, Pages 182: The Physicochemical Characterization of Unconventional Starches and Flours Used in Asia Foods doi: 10.3390/foods9020182 Authors: Grace Henry Starches and flours used commonly in Asia (tapioca, sweet potato, sago, water chestnut, and high amylose maize starch, red rice and kithul flour) were characterized in terms of their chemical composition, morphological, functional, pasting, thermal, gelling and in vitro digestibility properties. It was observed that...
Wed Feb 12, 2020 02:00
Foods, Vol. 9, Pages 181: Enhancement of the Anti-Inflammatory Effect of Mustard Kimchi on RAW 264.7 Macrophages by the Lactobacillus plantarum Fermentation-Mediated Generation of Phenolic Compound Derivatives Foods doi: 10.3390/foods9020181 Authors: Bao Le Pham Thi Ngoc Anh Seung Hwan Yang Mustard leaf kimchi contains numerous functional compounds that have various health benefits. However, the underlying mechanisms of their anti-inflammatory effects are unclear. In this study,...
Wed Feb 12, 2020 02:00
Foods, Vol. 9, Pages 179: Effect of High Pressure, Calcium Chloride and ZnO-Ag Nanoparticles on Beef Color and Shear Stress Foods doi: 10.3390/foods9020179 Authors: Panea Albertí Ripoll This study investigates how the use of a combination of high-pressure treatment, steak marination and active packaging influences beef color and shear stress. A 2 × 2 × 2 × 3 factorial design was applied, including pressure, marination, packaging and storage time....
Wed Feb 12, 2020 02:00
Foods, Vol. 9, Pages 178: Table Olives More than A Fermented Food Foods doi: 10.3390/foods9020178 Authors: Perpetuini Prete Garcia-Gonzalez Khairul Alam Corsetti Table olives are one of the oldest vegetable fermented foods in the Mediterranean area. Beside their economic impact, fermented table olives represent also an important healthy food in the Mediterranean diet, because of their high content of bioactive and health-promoting compounds. However, olive fermentation...
Wed Feb 12, 2020 02:00
Foods, Vol. 9, Pages 180: Changes in the Physical Properties of Calcium Alginate Gel Beads Under a Wide Range of Gelation Temperature Conditions Foods doi: 10.3390/foods9020180 Authors: Jeong Kim Lee Cho Kim Until now, most studies using calcium alginate gel (CAG) have been conducted primarily at room temperature (20 °C) without considering gelation temperature. Moreover, the effects of gelation temperature on the physical properties of CAG beads have not been...
Wed Feb 12, 2020 02:00
Foods, Vol. 9, Pages 176: Sensory and Physicochemical Analysis of Meat from Bovine Breeds in Different Livestock Production Systems, Pre-Slaughter Handling Conditions and Ageing Time Foods doi: 10.3390/foods9020176 Authors: López-Pedrouso Rodríguez-Vázquez Purriños Oliván García-Torres Sentandreu Lorenzo Zapata Franco Different bovine breeds and production systems are used worldwide, giving rise to differences in intrinsic and extrinsic characteristics...
Tue Feb 11, 2020 02:00
Foods, Vol. 9, Pages 177: Exploring Consumer Palatability of Australian Beef Fajita Meat Enhanced with Phosphate or Sodium Bicarbonate Foods doi: 10.3390/foods9020177 Authors: Garmyn Hardcastle Bendele Polkinghorne Miller The objective of this study was to determine the consumer eating quality of five Australian beef muscles (outside skirt/diaphragm, inside skirt/transversus abdominis, inside round cap/gracilis, bottom sirloin flap/obliquus abdominis internus, and flank...
Tue Feb 11, 2020 02:00
Foods, Vol. 9, Pages 175: Proximate Analysis and Nutritional Evaluation of Twenty Canadian Lentils by Principal Component and Cluster Analyses Foods doi: 10.3390/foods9020175 Authors: Ramdath Lu Maharaj Winberg Brummer Hawke Proximate composition and starch nutritional properties of twenty cooked lentils were assessed to identify unique varieties that could be used in value added foods. Significant variations exist among the lentil varieties (p < 0.05) with...
Tue Feb 11, 2020 02:00
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