Antibiotics, Vol. 9, Pages 88: Concerted Efforts Are Needed to Control and Mitigate Antibiotic Pollution in Coastal Waters of China Antibiotics doi: 10.3390/antibiotics9020088 Authors: Xie Du Chen Antibiotics have been applied for decades and antibiotic pollution is of great concern due to the risk for promoting resistant genes. Human activities such as mariculture and land-based discharge can lead to the antibiotic pollution in coastal area and it is of importance to assess...
Sun Feb 16, 2020 02:00
Antibiotics, Vol. 9, Pages 87: Antimicrobial Usage and Resistance in Companion Animals: A Cross-Sectional Study in Three European Countries Antibiotics doi: 10.3390/antibiotics9020087 Authors: Philip Joosten Daniela Ceccarelli Evelien Odent Steven Sarrazin Haitske Graveland Liese Van Gompel Antonio Battisti Andrea Caprioli Alessia Franco Jaap A. Wagenaar Dik Mevius Jeroen Dewulf Companion animals have been described as potential reservoirs of antimicrobial...
Sun Feb 16, 2020 02:00
Antibiotics, Vol. 9, Pages 86: Use of Micellar Liquid Chromatography to Determine Mebendazole in Dairy Products and Breeding Waste from Bovine Animals Antibiotics doi: 10.3390/antibiotics9020086 Authors: Prasad Pawar Mishra Durgbanshi Bose Albiol-Chiva Peris-Vicente García-Ferrer Esteve-Romero Mebendazole is an anthelmintic drug used in cattle production. However, residues may occur in produced food and in excretions, jeopardizing population health. A method...
Fri Feb 14, 2020 02:00
Antibiotics, Vol. 9, Pages 85: Brevinin-2GHk from Sylvirana guentheri and the Design of Truncated Analogs Exhibiting the Enhancement of Antimicrobial Activity Antibiotics doi: 10.3390/antibiotics9020085 Authors: Chen Miao Ma Zhou Shi Chen Burrows Xi Chen Wang Brevinins are an important antimicrobial peptide (AMP) family discovered in the skin secretions of Ranidae frogs. The members demonstrate a typical C-terminal ranabox, as well as a diverse range...
Fri Feb 14, 2020 02:00
Antibiotics, Vol. 9, Pages 84: Tigecycline Interferes with Fibrinogen Polymerization Independent of Peripheral Interactions with the Coagulation System Antibiotics doi: 10.3390/antibiotics9020084 Authors: Brandtner Bachler Fries Hermann Ruehlicke Fux Griesmacher Niederwanger Hell Treml Tigecycline offers broad anti-bacterial coverage for critically ill patients with complicated infections. A described but less researched side effect is coagulopathy....
Fri Feb 14, 2020 02:00
Antioxidants, Vol. 9, Pages 160: Chrysin Reduces Oxidative Stress but Does Not Affect Polyol Pathway in the Lenses of Type 1 Diabetic Rats Antioxidants doi: 10.3390/antiox9020160 Authors: Weronika Wojnar Maria Zych Sławomir Borymski Ilona Kaczmarczyk-Sedlak Prolonged hyperglycemia is one of the main causes of reactive oxygen species and free radicals generation in diabetes which may affect various organs, including the eye. Oxidative damage to proteins and lipids in the eye...
Sun Feb 16, 2020 02:00
Antioxidants, Vol. 9, Pages 159: Liposomal Resveratrol and/or Carvedilol Attenuate Doxorubicin-Induced Cardiotoxicity by Modulating Inflammation, Oxidative Stress and S100A1 in Rats Antioxidants doi: 10.3390/antiox9020159 Authors: Abeer M. Alanazi Laila Fadda Ahlam Alhusaini Rehab Ahmad Iman H. Hasan Ayman M. Mahmoud Doxorubicin (DOX) is a cytotoxic anthracycline antibiotic and one of the important chemotherapeutic agents for different types of cancers. DOX treatment is...
Sun Feb 16, 2020 02:00
Antioxidants, Vol. 9, Pages 158: Development of a Phytomelatonin-Rich Extract from Cultured Plants with Excellent Biochemical and Functional Properties as an Alternative to Synthetic Melatonin Antioxidants doi: 10.3390/antiox9020158 Authors: Francisca Pérez-Llamas Josefa Hernández-Ruiz Alberto Cuesta Salvador Zamora Marino B. Arnao Melatonin is a pleiotropic molecule with multiple and various functions. In recent years, there has been a considerable increase in the consumption...
Sun Feb 16, 2020 02:00
Antioxidants, Vol. 9, Pages 157: Free Radical Research in Cancer Antioxidants doi: 10.3390/antiox9020157 Authors: Ana Čipak Gašparović It can be challenging to find efficient therapy for cancer due to its biological diversity [...]
Sat Feb 15, 2020 02:00
Antioxidants, Vol. 9, Pages 156: Prediction of Antioxidant Activity of Cherry Fruits from UAS Multispectral Imagery Using Machine Learning Antioxidants doi: 10.3390/antiox9020156 Authors: Christos Karydas Miltiadis Iatrou Dimitrios Kouretas Anastasia Patouna George Iatrou Nikolaos Lazos Sandra Gewehr Xanthi Tseni Fotis Tekos Zois Zartaloudis Evangelos Mainos Spiros Mourelatos In this research, a model for the estimation of antioxidant content in cherry...
Fri Feb 14, 2020 02:00
Antioxidants, Vol. 9, Pages 155: Biological Redox Impact of Tocopherol Isomers Is Mediated by Fast Cytosolic Calcium Increases in Living Caco-2 Cells Antioxidants doi: 10.3390/antiox9020155 Authors: Miltha Hidalgo Vania Rodríguez Christine Kreindl Omar Porras Most of the biological impacts of Vitamin E, including the redox effects, have been raised from studies with α-tocopherol only, despite the fact that tocopherol-containing foods carry mixed tocopherol isomers....
Fri Feb 14, 2020 02:00
Antioxidants, Vol. 9, Pages 154: Fragaria vesca L. Extract: A Promising Cosmetic Ingredient with Antioxidant Properties Antioxidants doi: 10.3390/antiox9020154 Authors: Joana Couto Artur Figueirinha Maria Teresa Batista António Paranhos Carla Nunes Lídia Maria Gonçalves Joana Marto Manuel Fitas Pedro Pinto Helena Margarida Ribeiro Maria Eugénia Pina Fragaria vesca L. (F. vesca), popularly known as wild strawberry, is a plant from the Rosaceae family, found...
Fri Feb 14, 2020 02:00
Arts, Vol. 9, Pages 24: When the Image Takes over the Real: Holography and Its Potential within Acts of Visual Documentation Arts doi: 10.3390/arts9010024 Authors: Angela Bartram In Camera Lucida, Roland Barthes discusses the capacity of the photographic image to represent “flat death”. Documentation of an event, happening, or time is traditionally reliant on the photographic to determine its ephemeral existence and to secure its legacy within history. However, the...
Sat Feb 15, 2020 02:00
Arts, Vol. 9, Pages 23: Dance That “Suggested Nothing but Itself”: Josephine Baker and Abstraction Arts doi: 10.3390/arts9010023 Authors: Joanna Dee Das This article reconsiders Josephine Baker’s legacy for the field of dance by emphasizing the principles of abstraction that she developed through performance. Although she is considered to be a modernist, Baker is rarely discussed as an abstractionist. Doing so requires a rethinking of the relationship between race and abstraction,...
Fri Feb 14, 2020 02:00
Atmosphere, Vol. 11, Pages 207: Parameterization of Wave-Induced Mixing Using the Large Eddy Simulation (LES) (I) Atmosphere doi: 10.3390/atmos11020207 Authors: Wang Dong Yang Gao Turbulent motions in the thin ocean surface boundary layer control exchanges of momentum, heat and trace gases between the atmosphere and ocean. However, present parametric equations of turbulent motions that are applied to global climate models result in systematic or substantial errors in the...
Sat Feb 15, 2020 02:00
Atmosphere, Vol. 11, Pages 206: Near-Surface Ozone Variations in East Asia during Boreal Summer Atmosphere doi: 10.3390/atmos11020206 Authors: Jieun Wie Hyo-Jin Park Hyomee Lee Byung-Kwon Moon This study examined the variability of near-surface (850 hPa) ozone during summer in East Asia using simulations from 12 models participating in the Chemistry–Climate Model Initiative (CCMI). The empirical orthogonal function (EOF) analysis of non-detrended ozone shows that the...
Sat Feb 15, 2020 02:00
Atmosphere, Vol. 11, Pages 205: Sensitivity of Radiative Fluxes to Aerosols in the ALADIN-HIRLAM Numerical Weather Prediction System Atmosphere doi: 10.3390/atmos11020205 Authors: Laura Rontu Emily Gleeson Daniel Martin Perez Kristian Pagh Nielsen Velle Toll The direct radiative effect of aerosols is taken into account in many limited-area numerical weather prediction models using wavelength-dependent aerosol optical depths of a range of aerosol species. We studied the impact...
Fri Feb 14, 2020 02:00
Atmosphere, Vol. 11, Pages 204: Regulated and Non-Regulated Emissions from Euro 6 Diesel, Gasoline and CNG Vehicles under Real-World Driving Conditions Atmosphere doi: 10.3390/atmos11020204 Authors: Ricardo Suarez-Bertoa Martin Pechout Michal Vojtíšek Covadonga Astorga The transport sector is one of the main sources air pollutants. Different exhaust after-treatment systems have been implemented over the years to control the emissions of criteria pollutants. However, while reducing...
Fri Feb 14, 2020 02:00
Atmosphere, Vol. 11, Pages 203: Coupling Large Eddies and Waves in Turbulence: Case Study of Magnetic Helicity at the Ion Inertial Scale Atmosphere doi: 10.3390/atmos11020203 Authors: Annick Pouquet Julia E. Stawarz Duane Rosenberg In turbulence, for neutral or conducting fluids, a large ratio of scales is excited because of the possible occurrence of inverse cascades to large, global scales together with direct cascades to small, dissipative scales, as observed in the atmosphere...
Fri Feb 14, 2020 02:00
Atmosphere, Vol. 11, Pages 202: Characteristics of Black Carbon Particle-Bound Polycyclic Aromatic Hydrocarbons in Two Sites of Nanjing and Shanghai, China Atmosphere doi: 10.3390/atmos11020202 Authors: Cui Lei Wu Huang Shen Wang Qiao Zhou Zhu Ma Ge Airborne polycyclic aromatic hydrocarbons (PAHs) are of great concern to human health due to their potential high toxicity. Understanding the characteristics and sources of PAHs, as well as the governing...
Fri Feb 14, 2020 02:00
Biomedicines, Vol. 8, Pages 33: McArdle Disease: Clinical, Biochemical, Histological and Molecular Genetic Analysis of 60 Patients Biomedicines doi: 10.3390/biomedicines8020033 Authors: Pushpa Raj Joshi Marcus Deschauer Stephan Zierz A clinical, biochemical, histological and molecular genetic analysis of 60 McArdle patients (33 males and 27 females; mean age at diagnosis: 37 years) was performed. The objective of this study was to identify a possible genotype–phenotype...
Sat Feb 15, 2020 02:00
Biomolecules, Vol. 10, Pages 311: Integrative Transcriptomic and Metabolic Analyses Provide Insights into the Role of Trichomes in Tea Plant (Camellia Sinensis) Biomolecules doi: 10.3390/biom10020311 Authors: Hongli Cao Jiamin Li Yijun Ye Hongzheng Lin Zhilong Hao Naixing Ye Chuan Yue Trichomes, which develop from epidermal cells, are regarded as one of the key features that are involved in the evaluation of tea quality and tea germplasm resources. The metabolites from...
Sun Feb 16, 2020 02:00
Biomolecules, Vol. 10, Pages 310: Production, Characterization, and Bioactivity of Fish Protein Hydrolysates from Aquaculture Turbot (Scophthalmus maximus) Wastes Biomolecules doi: 10.3390/biom10020310 Authors: Vázquez Rodríguez-Amado Sotelo Sanz Pérez-Martín Valcárcel The valorization of wastes generated in the processing of farmed fish is currently an issue of extreme relevance for the industry, aiming to accomplish the objectives of circular bioeconomy. In the...
Sat Feb 15, 2020 02:00
Biomolecules, Vol. 10, Pages 309: Fluorescein Derivatives as Antibacterial Agents Acting via Membrane Depolarization Biomolecules doi: 10.3390/biom10020309 Authors: Nazarov Kirsanov Denisov Khailova Karakozova Lyamzaev Korshunova Lukyanov Kotova Antonenko Appending a lipophylic alkyl chain by ester bond to fluorescein has been previously shown to convert this popular dye into an effective protonophoric uncoupler of oxidative phosphorylation in mitochondria,...
Sat Feb 15, 2020 02:00
Biomolecules, Vol. 10, Pages 308: Regulation of Electromagnetic Perceptive Gene Using Ferromagnetic Particles for the External Control of Calcium Ion Transport Biomolecules doi: 10.3390/biom10020308 Authors: Jangsun Hwang Yonghyun Choi Kyungwoo Lee Vijai Krishnan Galit Pelled Assaf A. Gilad Jonghoon Choi Developing synthetic biological devices to allow the noninvasive control of cell fate and function, in vivo can potentially revolutionize the field of regenerative...
Sat Feb 15, 2020 02:00
Biomolecules, Vol. 10, Pages 307: p53’s Extended Reach: The Mutant p53 Secretome Biomolecules doi: 10.3390/biom10020307 Authors: Evangelos Pavlakis Thorsten Stiewe p53 suppresses tumorigenesis by activating a plethora of effector pathways. While most of these operate primarily inside of cells to limit proliferation and survival of incipient cancer cells, many extend to the extracellular space. In particular, p53 controls expression and secretion of numerous extracellular factors that...
Sat Feb 15, 2020 02:00
Biomolecules, Vol. 10, Pages 306: System-Based Differential Gene Network Analysis for Characterizing a Sample-Specific Subnetwork Biomolecules doi: 10.3390/biom10020306 Authors: Yoshihisa Tanaka Yoshinori Tamada Marie Ikeguchi Fumiyoshi Yamashita Yasushi Okuno Gene network estimation is a method key to understanding a fundamental cellular system from high throughput omics data. However, the existing gene network analysis relies on having a sufficient number of samples and...
Fri Feb 14, 2020 02:00
Biomolecules, Vol. 10, Pages 304: Targeting the Class A Carbapenemase GES-5 via Virtual Screening Biomolecules doi: 10.3390/biom10020304 Authors: Klein Cendron Montanari Bellio Celenza Maso Tondi Brenk The worldwide spread of β-lactamases able to hydrolyze last resort carbapenems contributes to the antibiotic resistance problem and menaces the successful antimicrobial treatment of clinically relevant pathogens. Class A carbapenemases include members...
Fri Feb 14, 2020 02:00
Biomolecules, Vol. 10, Pages 305: Phytochemicals in Garlic Extract Inhibit Therapeutic Enzyme DPP-4 and Induce Skeletal Muscle Cell Proliferation: A Possible Mechanism of Action to Benefit the Treatment of Diabetes Mellitus Biomolecules doi: 10.3390/biom10020305 Authors: Poonam Kalhotra Veera C.S.R. Chittepu Guillermo Osorio-Revilla Tzayhri Gallardo-Velazquez Diabetes mellitus is a severe health problem in Mexico, and its prevalence is increasing exponentially every year. Recently,...
Fri Feb 14, 2020 02:00
Biomolecules, Vol. 10, Pages 303: Follow the Mutations: Toward Class-Specific, Small-Molecule Reactivation of p53 Biomolecules doi: 10.3390/biom10020303 Authors: Loh The mutational landscape of p53 in cancer is unusual among tumor suppressors because most of the alterations are of the missense type and localize to a single domain: the ~220 amino acid DNA-binding domain. Nearly all of these mutations produce the common effect of reducing p53’s ability to interact with DNA and...
Fri Feb 14, 2020 02:00
Biomolecules, Vol. 10, Pages 302: Sodium Thiosulfate in the Pregnant Dahl Salt-Sensitive Rat, a Model of Preeclampsia Biomolecules doi: 10.3390/biom10020302 Authors: Terstappen Clarke Joles Ross Garrett Minnion Feelisch Goor Sasser Lely Aberrant production of hydrogen sulfide (H2S) has been linked to preeclampsia. We hypothesized that sodium thiosulfate (STS), a H2S donor, reduces hypertension and proteinuria, and diminishes fetal growth restriction...
Fri Feb 14, 2020 02:00
Biomolecules, Vol. 10, Pages 301: Recent Advances in Molecular Mechanisms of the NKG2D Pathway in Hepatocellular Carcinoma Biomolecules doi: 10.3390/biom10020301 Authors: Wang Li Sun Hepatocellular carcinoma is a common malignant tumor with high mortality. Its malignant proliferation, invasion, and metastasis are closely related to the cellular immune function of the patients. NKG2D is a key activated and type II membrane protein molecule expressed on the surface of almost all...
Fri Feb 14, 2020 02:00
Biomolecules, Vol. 10, Pages 300: Increased Arginase Expression and Decreased Nitric Oxide in Pig Donor Lungs after Normothermic Ex Vivo Lung Perfusion Biomolecules doi: 10.3390/biom10020300 Authors: Tavasoli Liu Machuca Bonato Grant Cypel Keshavjee Grasemann An established pig lung transplantation model was used to study the effects of cold ischemia time, normothermic acellular ex vivo lung perfusion (EVLP) and reperfusion after lung transplantation on l-arginine/NO...
Fri Feb 14, 2020 02:00
Biomolecules, Vol. 10, Pages 299: Biochemical and Behavioral Characterization of IN14, a New Inhibitor of HDACs with Antidepressant-Like Properties Biomolecules doi: 10.3390/biom10020299 Authors: Martínez-Pacheco Picazo López-Torres Morin Castro-Cerritos Zepeda Roldán-Roldán Evidence suggests that histone deacetylases (HDACs) inhibitors could be used as an effective treatment for some psychiatric and neurological conditions such as depression, anxiety and age-related...
Fri Feb 14, 2020 02:00
Biosensors, Vol. 10, Pages 13: Detection of the Ovarian Cancer Biomarker Lysophosphatidic Acid in Serum Biosensors doi: 10.3390/bios10020013 Authors: Brian De La Franier Michael Thompson Lysophosphatidic acid (LPA) is present during the medical condition of ovarian cancer at all stages of the disease, and, therefore possesses considerable potential as a biomarker for screening its presence in female patients. Unfortunately, there is currently no clinically employable assay for this...
Fri Feb 14, 2020 02:00
Brain Sciences, Vol. 10, Pages 105: Focus on Clozapine Withdrawal- and Misuse-Related Cases as Reported to the European Medicines Agency (EMA) Pharmacovigilance Database Brain Sciences doi: 10.3390/brainsci10020105 Authors: Stefania Chiappini Fabrizio Schifano John Martin Corkery Amira Guirguis Background: Clozapine is of high clinical relevance for the management of both treatment-resistant schizophrenia and psychotic disturbances with concurrent drug misuse. Although the molecule...
Sun Feb 16, 2020 02:00
Brain Sciences, Vol. 10, Pages 104: Emotional Response Inhibition: A Shared Neurocognitive Deficit in Eating Disorder Symptoms and Nonsuicidal Self-Injury Brain Sciences doi: 10.3390/brainsci10020104 Authors: Kenneth J. D. Allen M. McLean Sammon Kathryn R. Fox Jeremy G. Stewart Eating disorder (ED) symptoms often co-occur with non-suicidal self-injury (NSSI). This comorbidity is consistent with evidence that trait negative urgency increases risk for both of these phenomena....
Sat Feb 15, 2020 02:00
Brain Sciences, Vol. 10, Pages 103: Sex Stratified Treatment of Neurological Disorders: Challenges and Perspectives Brain Sciences doi: 10.3390/brainsci10020103 Authors: Nalvarte Despite the obvious sex differences in many of the most common neuropsychiatric and neurodegenerative disorders, males and females are still often treated the same from a clinical perspective. Why is that? The simple answer is that there is still too little known about this very complex matter. Sex hormone...
Fri Feb 14, 2020 02:00
Cancers, Vol. 12, Pages 457: Cold Atmospheric Plasma and Gold Quantum Dots Exert Dual Cytotoxicity Mediated by the Cell Receptor-Activated Apoptotic Pathway in Glioblastoma Cells Cancers doi: 10.3390/cancers12020457 Authors: Nagendra Kumar Kaushik Neha Kaushik Rizwan Wahab Pradeep Bhartiya Nguyen Nhat Linh Farheen Khan Abdulaziz A. Al-Khedhairy Eun Ha Choi Brain cancer malignancies represent an immense challenge for research and clinical oncology. Glioblastoma is...
Sun Feb 16, 2020 02:00
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