Particles, Vol. 3, Pages 114-122: Particle Production in XeXe Collisions at the LHC within the Integrated Hydrokinetic Model+ Particles doi: 10.3390/particles3010010 Authors: Yuri Sinyukov Musfer Adzhymambetov Volodymyr Shapoval The paper is devoted to the theoretical study of particle production in the Large Hadron Collider (LHC) Xe+Xe collisions at the energy s N N = 5 . 44 TeV. The description of common bulk observables, such as mean charged particle multiplicity,...
Tue Feb 18, 2020 02:00
Pathogens, Vol. 9, Pages 134: To What Extent Should We Rely on Antibiotics to Reduce High Gonococcal Prevalence? Historical Insights from Mass-Meningococcal Campaigns Pathogens doi: 10.3390/pathogens9020134 Authors: Kenyon In the absence of a vaccine, current antibiotic-dependent efforts to reduce the prevalence of Neisseria gonorrhoeae in high prevalence populations have been shown to result in extremely high levels of antibiotic consumption. No randomized controlled trials have been...
Tue Feb 18, 2020 02:00
Pathogens, Vol. 9, Pages 132: Identification of a Neisseria gonorrhoeae Histone Deacetylase: Epigenetic Impact on Host Gene Expression Pathogens doi: 10.3390/pathogens9020132 Authors: Susu M. Zughaier Corinne E. Rouquette-Loughlin William M. Shafer Epigenetic reprogramming in macrophages is termed trained innate immunity, which regulates immune tolerance and limits tissue damage during infection. Neisseria gonorrhoeae is a strict human pathogen that causes the sexually transmitted...
Tue Feb 18, 2020 02:00
Pathogens, Vol. 9, Pages 133: HPV Oncoproteins and the Ubiquitin Proteasome System: A Signature of Malignancy? Pathogens doi: 10.3390/pathogens9020133 Authors: Anamaria Đukić Lucija Lulić Miranda Thomas Josipa Skelin Nathaniel Edward Bennett Saidu Magdalena Grce Lawrence Banks Vjekoslav Tomaić Human papillomavirus (HPV) E6 and E7 oncoproteins are critical for development and maintenance of the malignant phenotype in HPV-induced cancers. These two viral oncoproteins...
Tue Feb 18, 2020 02:00
Pathogens, Vol. 9, Pages 131: Metabolic Changes of Mycobacterium tuberculosis during the Anti-Tuberculosis Therapy Pathogens doi: 10.3390/pathogens9020131 Authors: Bespyatykh Shitikov Bespiatykh Guliaev Klimina Veselovsky Arapidi Dogonadze Zhuravlev Ilina Govorun Tuberculosis, caused by Mycobacterium tuberculosis complex bacteria, remains one of the most pressing health problems. Despite the general trend towards reduction of the disease incidence...
Tue Feb 18, 2020 02:00
Pathogens, Vol. 9, Pages 130: Host Factors Affecting Generation of Immunity against Porcine Epidemic Diarrhea Virus in Pregnant and Lactating Swine and Passive Protection of Neonates Pathogens doi: 10.3390/pathogens9020130 Authors: Langel Wang Vlasova Saif Porcine epidemic diarrhea virus (PEDV) is a highly virulent re-emerging enteric coronavirus that causes acute diarrhea, dehydration, and up to 100% mortality in neonatal suckling piglets. Despite this, a safe and effective...
Tue Feb 18, 2020 02:00
Pharmaceutics, Vol. 12, Pages 170: pH-Sensitive Mixed Micelles Assembled from PDEAEMA-PPEGMA and PCL-PPEGMA for Doxorubicin Delivery: Experimental and DPD Simulations Study Pharmaceutics doi: 10.3390/pharmaceutics12020170 Authors: Yang Liu Xiao Yuan Chen Guo Yue Zhu Lin Tang Dong To decrease critical micelle concentration (CMC), improve stability, and keep high drug-loading capacity, three pH-sensitive mixed micelles applied for anticancer drug...
Tue Feb 18, 2020 02:00
Pharmaceutics, Vol. 12, Pages 171: Nanomaterials Designed for Antiviral Drug Delivery Transport across Biological Barriers Pharmaceutics doi: 10.3390/pharmaceutics12020171 Authors: Florina-Daniela Cojocaru Doru Botezat Ioannis Gardikiotis Cristina-Mariana Uritu Gianina Dodi Laura Trandafir Ciprian Rezus Elena Rezus Bogdan-Ionel Tamba Cosmin-Teodor Mihai Viral infections are a major global health problem, representing a significant cause of mortality with an...
Tue Feb 18, 2020 02:00
Pharmaceutics, Vol. 12, Pages 169: Zein/MCM-41 Nanocomposite Film Incorporated with Cinnamon Essential Oil Loaded by Modified Supercritical CO2 Impregnation for Long-Term Antibacterial Packaging Pharmaceutics doi: 10.3390/pharmaceutics12020169 Authors: Xiaojing Liu Jingfu Jia Shulei Duan Xue Zhou Anya Xiang Ziling Lian Fahuan Ge Antimicrobial medicine and food packages based on bio-based film containing essential oils have attracted great attention worldwide. However,...
Tue Feb 18, 2020 02:00
Pharmacy, Vol. 8, Pages 21: Adaptive Expertise in Continuing Pharmacy Professional Development Pharmacy doi: 10.3390/pharmacy8010021 Authors: Naomi Steenhof Pharmacists are facing rapid changes and increasing complexity in the workplace. The astounding rate of both the evolution and the development of knowledge in pharmacy practice requires that we develop continuing professional development (CPD) to foster and support innovation, creativity, and flexibility, alongside procedural expertise....
Tue Feb 18, 2020 02:00
Plants, Vol. 9, Pages 270: Rooibos (Aspalathus linearis) Genome Size Estimation Using Flow Cytometry and K-Mer Analyses Plants doi: 10.3390/plants9020270 Authors: Mgwatyu Stander Ferreira Williams Hesse Plant genomes provide information on biosynthetic pathways involved in the production of industrially relevant compounds. Genome size estimates are essential for the initiation of genome projects. The genome size of rooibos (Aspalathus linearis species complex) was estimated...
Tue Feb 18, 2020 02:00
Plants, Vol. 9, Pages 269: Combined Effects of UV-B and Drought on Native and Exotic Populations of Verbascum thapsus L. Plants doi: 10.3390/plants9020269 Authors: Hock Plos Sporbert Erfmeier During plant invasions, exotic species have to face new environmental challenges and are affected by interacting components of global change, which may include more stressful environmental conditions. We investigated an invasive species of New Zealand grasslands, commonly exposed to...
Tue Feb 18, 2020 02:00
Plants, Vol. 9, Pages 263: Metagenomic Insights of the Root Colonizing Microbiome Associated with Symptomatic and Non-Symptomatic Bananas in Fusarium Wilt Infected Fields Plants doi: 10.3390/plants9020263 Authors: Manoj Kaushal George Mahuku Rony Swennen Plants tissues are colonized by diverse communities of microorganisms called endophytes. They are key determinants of plant production and health, for example by facilitating nutrient exchanges or limiting disease development....
Tue Feb 18, 2020 02:00
Plants, Vol. 9, Pages 265: Chemical Composition of Aerial Parts Essential Oils from Six Endemic Malagasy Helichrysum Species Plants doi: 10.3390/plants9020265 Authors: Rabehaja Bezert Rakotonandrasana Ramanoelina Andrianjara Bighelli Tomi Paoli The essential oils of six endemic Malagasy Helichrysum species were investigated by GC (RI), GC–MS and 13C NMR spectrometry. In total, 153 compounds were identified accounting for 90.8% to 99.9% of the total...
Tue Feb 18, 2020 02:00
Plants, Vol. 9, Pages 267: In Vitro Anti-HSV-1 Activity of Polyphenol-Rich Extracts and Pure Polyphenol Compounds Derived from Pistachios Kernels (Pistacia vera L.) Plants doi: 10.3390/plants9020267 Authors: Musarra-Pizzo Pennisi Ben-Amor Smeriglio Mandalari Sciortino Natural compounds are a prominent source of novel antiviral drugs. Several reports have previously shown the antimicrobial activity of pistachio polyphenol extracts. Therefore, the aim of our research...
Tue Feb 18, 2020 02:00
Plants, Vol. 9, Pages 266: Endophytic Bacterial Microbiome Diversity in Early Developmental Stage Plant Tissues of Wheat Varieties Plants doi: 10.3390/plants9020266 Authors: Žiarovská Medo Kyseľ Zamiešková Kačániová Endophytic bacteria are an important part of different functions in plants that lead to plants’ production characteristics as well as their stress response mechanisms. Endophytic bacterial diversity was analyzed in this study to describe 16S rRNA...
Tue Feb 18, 2020 02:00
Plants, Vol. 9, Pages 264: Plant Growth Inhibitory Activities and Volatile Active Compounds of 53 Spices and Herbs Plants doi: 10.3390/plants9020264 Authors: Takayuki Sekine Kwame Sarpong Appiah Majid Azizi Yoshiharu Fujii The inhibitory activities of the leachates and volatiles from 53 plant species (spices and herbs) were evaluated against lettuce (Lactuca sativa “Great Lakes 366”) seedling growth using the sandwich and dish pack methods, respectively....
Tue Feb 18, 2020 02:00
Plants, Vol. 9, Pages 268: CRISPR/Cas9-Mediated Mutagenesis of RCO in Cardamine hirsuta Plants doi: 10.3390/plants9020268 Authors: Alvim Kamei Pieper Laurent Tsiantis Huijser The small crucifer Cardamine hirsuta bears complex leaves divided into leaflets. This is in contrast to its relative, the reference plant Arabidopsis thaliana, which has simple leaves. Comparative studies between these species provide attractive opportunities to study the diversification of form....
Tue Feb 18, 2020 02:00
Plants, Vol. 9, Pages 262: Long-Chain acyl-CoA Synthetase LACS2 Contributes to Submergence Tolerance by Modulating Cuticle Permeability in Arabidopsis Plants doi: 10.3390/plants9020262 Authors: Li-Juan Xie Wei-Juan Tan Yi-Cong Yang Yi-Fang Tan Ying Zhou De-Mian Zhou Shi Xiao Qin-Fang Chen In Arabidopsis thaliana, LONG-CHAIN ACYL-COA SYNTHETASEs (LACSs) catalyze the synthesis of long-chain acyl-CoAs and function in diverse biological processes. We have recently revealed...
Tue Feb 18, 2020 02:00
Plants, Vol. 9, Pages 261: Mitochondrial DNA Repair in an Arabidopsis thaliana Uracil N-Glycosylase Mutant Plants doi: 10.3390/plants9020261 Authors: Wynn Purfeerst Christensen Substitution rates in plant mitochondrial genes are extremely low, indicating strong selective pressure as well as efficient repair. Plant mitochondria possess base excision repair pathways; however, many repair pathways such as nucleotide excision repair and mismatch repair appear to be absent. In the...
Tue Feb 18, 2020 02:00
Plants, Vol. 9, Pages 260: Assessment of Genetic Diversity of the “Acquaviva Red Onion” (Allium cepa L.) Apulian Landrace Plants doi: 10.3390/plants9020260 Authors: Luigi Ricciardi Rosa Mazzeo Angelo Raffaele Marcotrigiano Guglielmo Rainaldi Paolo Iovieno Vito Zonno Stefano Pavan Concetta Lotti Onion (Allium cepa L.) is the second most important vegetable crop worldwide and is widely appreciated for its health benefits. Despite its significant economic importance...
Tue Feb 18, 2020 02:00
Plants, Vol. 9, Pages 259: Co-Suppression of NbClpC1 and NbClpC2, Encoding Clp Protease Chaperons, Elicits Significant Changes in the Metabolic Profile of Nicotiana benthamiana Plants doi: 10.3390/plants9020259 Authors: Ali Baek Metabolites in plants are the products of cellular metabolic processes, and their differential amount can be regarded as the final responses of plants to genetic, epigenetic, or environmental stresses. The Clp protease complex, composed of the chaperonic...
Tue Feb 18, 2020 02:00
Plasma, Vol. 3, Pages 12-26: Modelling of an Atmospheric–Pressure Air Glow Discharge Operating in High–Gas Temperature Regimes: The Role of the Associative Ionization Reactions Involving Excited Atoms Plasma doi: 10.3390/plasma3010003 Authors: Cejas Mancinelli Prevosto A model of a stationary glow-type discharge in atmospheric-pressure air operated in high-gas-temperature regimes (1000 K < Tg < 6000 K), with a focus on the role of associative ionization reactions...
Tue Feb 18, 2020 02:00
Religions, Vol. 11, Pages 94: Religion and the Limits of Metatheatre in Our Town and Sunday in the Park with George Religions doi: 10.3390/rel11020094 Authors: Larry D. Bouchard This essay explores theatrical drama alongside aspects of religious dimensionality David Tracy analyzes in terms of limit experience, limit language, and limit questions. The claim is that metatheatrical forms can correlate with limit dimensions, a correlation which may prove as pertinent as ritual for linking...
Tue Feb 18, 2020 02:00
Religions, Vol. 11, Pages 93: The Burka Ban: Islamic Dress, Freedom and Choice in The Netherlands in Light of the 2019 Burka Ban Law Religions doi: 10.3390/rel11020093 Authors: Hass This article, part of an evolving and large project, examines the relationship between clothing, freedom and choice, and specifically Islamic dress in shaping the identity of Dutch Muslim women after the Burka Ban that was voted into law on 1 August 2019 in the Netherlands. It discusses the debates before...
Tue Feb 18, 2020 02:00
Religions, Vol. 11, Pages 92: Religious Diversity in Australia: Rethinking Social Cohesion Religions doi: 10.3390/rel11020092 Authors: Ezzy Bouma Barton Halafoff Banham Jackson Beaman This paper argues for a reconsideration of social cohesion as an analytical concept and a policy goal in response to increasing levels of religious diversity in contemporary Australia. In recent decades, Australian has seen a revitalization of religion, increasing numbers of those...
Tue Feb 18, 2020 02:00
Sports, Vol. 8, Pages 23: Validating Physiological and Biomechanical Parameters during Intermittent Swimming at Speed Corresponding to Lactate Concentration of 4 mmol·L‒1 Sports doi: 10.3390/sports8020023 Authors: Arsoniadis Nikitakis Botonis Malliaros Toubekis Background: Physiological and biomechanical parameters obtained during testing need validation in a training setting. The purpose of this study was to compare parameters calculated by a 5 × 200-m test...
Tue Feb 18, 2020 02:00
Sports, Vol. 8, Pages 24: Retraction: Stein, J.A. et al. The Effects of Acute Caffeine Supplementation on Performance in Trained CrossFit Athletes. Sports 2019, 7, 95 Sports doi: 10.3390/sports8020024 Authors: Stein Ramirez Heinrich All authors of the published article [1] have agreed to retract it based on the basis of a data entry error (Figure 1) [...]
Tue Feb 18, 2020 02:00
Toxins, Vol. 12, Pages 127: Efficacy and Safety of OnabotulinumtoxinA 400 Units in Patients with Post-Stroke Upper Limb Spasticity: Final Report of a Randomized, Double-Blind, Placebo-Controlled Trial with an Open-Label Extension Phase Toxins doi: 10.3390/toxins12020127 Authors: Masahiro Abo Takashi Shigematsu Hiroyoshi Hara Yasuko Matsuda Akinori Nimura Yoshiyuki Yamashita Kaoru Takahashi In many countries, 400 units (U) is the maximum dose of onabotulinumtoxinA available...
Tue Feb 18, 2020 02:00
Toxins, Vol. 12, Pages 128: Comparing the Efficacy of OnabotulinumtoxinA, Sacral Neuromodulation, and Peripheral Tibial Nerve Stimulation as Third Line Treatment for the Management of Overactive Bladder Symptoms in Adults: Systematic Review and Network Meta-Analysis Toxins doi: 10.3390/toxins12020128 Authors: Chi-Wen Lo Mei-Yi Wu Stephen Shei-Dei Yang Fu-Shan Jaw Shang-Jen Chang The American Urological Association guidelines for the management of non-neurogenic overactive...
Tue Feb 18, 2020 02:00
Toxins, Vol. 12, Pages 129: Mechanism of Action of Botulinum Toxin A in Treatment of Functional Urological Disorders Toxins doi: 10.3390/toxins12020129 Authors: Yu-Hua Lin Bing-Juin Chiang Chun-Hou Liao Intravesical botulinum toxin (BoNT) injection is effective in reducing urgency and urinary incontinence. It temporarily inhibits the detrusor muscle contraction by blocking the release of acetylcholine (Ach) from the preganglionic and postganglionic nerves in the efferent nerves....
Tue Feb 18, 2020 02:00
Toxins, Vol. 12, Pages 126: Phytotoxic Metabolites Isolated from Neufusicoccum batangarum, the Causal Agent of the Scabby Canker of Cactus Pear (Opuntia ficus-indica L.) Toxins doi: 10.3390/toxins12020126 Authors: Masi Aloi Nocera Cacciola Surico Evidente Six phytotoxins were obtained from the culture filtrates of the ascomycete Neofusicoccum batangarum, the causal agent of the scabby canker of cactus pear (Opuntia ficus-indica L.) in minor Sicily islands. The phytotoxins...
Tue Feb 18, 2020 02:00
Veterinary Sciences, Vol. 7, Pages 25: Schirmer Tear Test Value and Corneal Lesions’ Incidence during General Anesthesia for Non-Ophthalmic Surgery in Non-Brachycephalic Dogs: A Pilot Study Comparing Three Different Lubricant Eye Drop Formulations Veterinary Sciences doi: 10.3390/vetsci7010025 Authors: Cristina Di Palma Fabiana Micieli Barbara Lamagna Annalisa Nieddu Valeria Uccello Gerardo Fatone Giancarlo Vesce Aim of this blinded, prospective, randomized clinical...
Tue Feb 18, 2020 02:00
Viruses, Vol. 12, Pages 225: An Oleanolic Acid Derivative Inhibits Hemagglutinin-Mediated Entry of Influenza A Virus Viruses doi: 10.3390/v12020225 Authors: Mengdie Ye Yixian Liao Li Wu Wenbao Qi Namrta Choudhry Yahong Liu Weisan Chen Gaopeng Song Jianxin Chen Influenza A viruses (IAV) have been a major public health threat worldwide, and options for antiviral therapy become increasingly limited with the emergence of drug-resisting virus strains. New and effective...
Tue Feb 18, 2020 02:00
Viruses, Vol. 12, Pages 227: The Major Capsid Protein, VP1, of the Mouse Polyomavirus Stimulates the Activity of Tubulin Acetyltransferase 1 by Microtubule Stabilization Viruses doi: 10.3390/v12020227 Authors: Horníková Bruštíková Ryabchenko Zhernov Fraiberk Mariničová Lánský Forstová Viruses have evolved mechanisms to manipulate microtubules (MTs) for the efficient realization of their replication programs. Studying the mechanisms of replication of mouse...
Tue Feb 18, 2020 02:00
Viruses, Vol. 12, Pages 226: Analytical Performance of the RIDASCREEN® Hantavirus Puumala IgG/IgM ELISA Assay Viruses doi: 10.3390/v12020226 Authors: Melissa Depypere Katrien Lagrou Marjan Van Esbroeck Els Houben Marc Van Ranst The National Reference Center for Hantavirus in Belgium is currently using the Hantavirus IgM/IgG ELISA Progen kit (Heidelberg, Germany) for the detection of the most prevalent Hantavirus in Western Europe, Puumala virus (PUUV). Two commercially available...
Tue Feb 18, 2020 02:00
Viruses, Vol. 12, Pages 228: A Novel Role for PX, a Structural Protein of Fowl Adenovirus Serotype 4 (FAdV4), as an Apoptosis-Inducer in Leghorn Male Hepatocellular Cell Viruses doi: 10.3390/v12020228 Authors: Zhao Duan Wang Gao Cao Li Zheng Hydropericardium-Hepatitis Syndrome (HHS) caused by Fowl Adenovirus Serotype 4 (FAdV4) infection is a severe threat to the poultry industry worldwide, especially in China since 2015. Recent studies show that FAdV4 induces...
Tue Feb 18, 2020 02:00
Viruses, Vol. 12, Pages 224: Visualizing Sacbrood Virus of Honey Bees via Transformation and Coupling with Enhanced Green Fluorescent Protein Viruses doi: 10.3390/v12020224 Authors: Lang Jin Shahid Mehmood Giikailang Zhang Yuwei Song Songkun Su Shaokang Huang Heliang Huang Yakun Zhang Haiyang Geng Wei-Fone Huang Sacbrood virus (SBV) of honey bees is a picornavirus in the genus Iflavirus. Given its relatively small and simple genome structure, single positive-strand...
Tue Feb 18, 2020 02:00
Water, Vol. 12, Pages 566: Social Innovations as A Response to Dispossession: Community Water Management in View of Socio-Metabolic Rift in Chile Water doi: 10.3390/w12020566 Authors: Ilka Roose Alexander Panez Chile has gone through more than four decades of neoliberalism, inaugurated by the civil–military dictatorship (1973–1990). One of the central aspects of the current model is the neoliberal exploitation of natural commons such as land, water and minerals....
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Water, Vol. 12, Pages 565: High-Resolution, In Situ Monitoring of Stable Isotopes of Water Revealed Insight into Hydrological Response Behavior Water doi: 10.3390/w12020565 Authors: Amir Sahraei Philipp Kraft David Windhorst Lutz Breuer High temporal resolution (20-min intervals) measurements of stable isotopes from groundwater, stream water and precipitation were investigated to understand the hydrological response behavior and control of precipitation and antecedent wetness...
Tue Feb 18, 2020 02:00
Water, Vol. 12, Pages 564: Future Landslide Characteristic Assessment Using Ensemble Climate Change Scenarios: A Case Study in Taiwan Water doi: 10.3390/w12020564 Authors: Chen Chen Chao Tung Liou Li Cheng Affected by climate change owing to global warming, the frequency of extreme rainfall events has gradually increased in recent years. Many studies have analyzed the impacts of climate change in various fields. However, uncertainty about the scenarios they used...
Tue Feb 18, 2020 02:00
Water, Vol. 12, Pages 561: Uncertainty Analysis of a 1D River Hydraulic Model with Adaptive Calibration Water doi: 10.3390/w12020561 Authors: Bessar Matte Anctil Water level modeling is a critical component of flood warning systems. A high-quality forecast requires the development of a hydraulic model that reliably accounts for the main sources of uncertainty. In this paper, a 1D hydraulic model with adaptive flow-based calibration was developed. This calibration resulted in...
Tue Feb 18, 2020 02:00
Water, Vol. 12, Pages 563: Geomorphology as a Driver of Heavy Metal Accumulation Patterns in a Floodplain Water doi: 10.3390/w12020563 Authors: Szabó Buró Szabó Tóth Baranyai Herman Prokisch Tomor Szabó The spatial complexity of floodplains is a function of several processes: hydrodynamics, flow direction, sediment transportation, and land use. Sediments can bind toxic elements, and as there are several pollution sources, the risk of heavy metal accumulation...
Tue Feb 18, 2020 02:00
Water, Vol. 12, Pages 562: Specific Types and Adaptability Evaluation of Managed Aquifer Recharge for Irrigation in the North China Plain Water doi: 10.3390/w12020562 Authors: Shuai Liu Weiping Wang Shisong Qu Yan Zheng Wenliang Li The North China Plain is the main grain production district in China, with a large area of well irrigation resulting in a large groundwater depression cone. In the 1970s and 1980s, small-scale managed aquifer recharge (MAR) projects were developed...
Tue Feb 18, 2020 02:00
Water, Vol. 12, Pages 560: Sound Velocity in a Thin Shallowly Submerged Terrestrial-Marine Quaternary Succession (Northern Adriatic Sea) Water doi: 10.3390/w12020560 Authors: Novak Šmuc Poglajen Celarc Vrabec Estimating sound velocity in seabed sediment of shallow near-shore areas submerged after the Last Glacial Maximum is often difficult due to the heterogeneous sedimentary composition resulting from sea-level changes affecting the sedimentary environments. The complex...
Tue Feb 18, 2020 02:00
Water, Vol. 12, Pages 559: Assessment of Biological and Sanitary Condition of Alien Fish from a High-Mountain Lake (Cottian Alps) Water doi: 10.3390/w12020559 Authors: Paolo Pastorino Marino Prearo Marco Bertoli Vasco Menconi Giuseppe Esposito Marzia Righetti Davide Mugetti Sabina Pederiva Maria Cesarina Abete Elisabetta Pizzul This study aimed to assess the biological and sanitary conditions of alien fish in a high-mountain lake (Balma Lake) located in the...
Tue Feb 18, 2020 02:00
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